3,249 research outputs found

    Magnetic Linear Birefringence Measurements Using Pulsed Fields

    Full text link
    In this paper we present the realization of further steps towards the measurement of the magnetic birefringence of the vacuum using pulsed fields. After describing our experiment, we report the calibration of our apparatus using nitrogen gas and we discuss the precision of our measurement giving a detailed error budget. Our best present vacuum upper limit is Dn < 5.0x10^(-20) T^-2 per 4 ms acquisition time. We finally discuss the improvements necessary to reach our final goal.Comment: submitted to Phys. Rev.

    Following successful anti-leishmanial treatment, neutrophil counts, CD10 expression and phagocytic capacity remain reduced in visceral leishmaniasis patients co-infected with HIV

    Get PDF
    Visceral leishmaniasis (VL) patients co-infected with HIV (VL/HIV patients) experience frequent treatment failures, VL relapses, opportunistic infections, and higher mortality. Their immune system remains profoundly suppressed after clinical cure and they maintain higher parasite load. This is in contrast with patients with VL alone (VL patients). Since neutrophils play a critical role in the control of Leishmania replication and the regulation of immune responses, we tested the hypothesis that neutrophil activation status and effector functions are fully restored in VL, but not in VL/HIV patients. Our results show the neutrophil counts and all activation markers and effector functions tested in our study were reduced at the time of diagnosis in VL and VL/HIV patients as compared to controls. CD62L, CD63, arginase 1 expression levels and reactive oxygen species production were restored at the end of treatment in both groups. However, neutrophil counts, CD10 expression and phagocytosis remained significantly lower throughout follow-up in VL/HIV patients; suggesting that dysregulated neutrophils contribute to the impaired host defence against pathogens in VL/HIV patients

    Microphase separation in Pr0.67Ca0.33MnO3 by small angle neutron scattering

    Full text link
    We have evidenced by small angle neutron scattering at low temperature the coexistence of ferromagnetism (F) and antiferromagnetism (AF) in Pr0.67Ca0.33MnO3. The results are compared to those obtained in Pr0.80Ca0.20MnO3 and Pr0.63Ca0.37MnO3, which are F and AF respectively. Quantitative analysis shows that the small angle scattering is not due to a mesoscopic mixing but to a nanoscopic electronic and magnetic ''red cabbage'' structure, in which the ferromagnetic phase exists in form of thin layers in the AF matrix (stripes or 2D ''sheets'').Comment: 4 figure

    Are white storks addicted to junk food? Impacts of landfill use on the movement and behaviour of resident white storks (Ciconia ciconia) from a partially migratory population

    Get PDF
    Background: The migratory patterns of animals are changing in response to global environmental change with many species forming resident populations in areas where they were once migratory. The white stork (Ciconia ciconia) was wholly migratory in Europe but recently guaranteed, year-round food from landfill sites has facilitated the establishment of resident populations in Iberia. In this study 17 resident white storks were fitted with GPS/GSM data loggers (including accelerometer) and tracked for 9.1 ± 3.7 months to quantify the extent and consistency of landfill attendance by individuals during the non-breeding and breeding seasons and to assess the influence of landfill use on daily distances travelled, percentage of GPS fixes spent foraging and non-landfill foraging ranges. Results: Resident white storks used landfill more during non-breeding (20.1 % ± 2.3 of foraging GPS fixes) than during breeding (14.9 % ± 2.2). Landfill attendance declined with increasing distance between nest and landfill in both seasons. During non-breeding a large percentage of GPS fixes occurred on the nest throughout the day (27 % ± 3.0 of fixes) in the majority of tagged storks. This study provides first confirmation of year-round nest use by resident white storks. The percentage of GPS fixes on the nest was not influenced by the distance between nest and the landfill site. Storks travelled up to 48.2 km to visit landfills during non-breeding and a maximum of 28.1 km during breeding, notably further than previous estimates. Storks nesting close to landfill sites used landfill more and had smaller foraging ranges in non-landfill habitat indicating higher reliance on landfill. The majority of non-landfill foraging occurred around the nest and long distance trips were made specifically to visit landfill. Conclusions: The continuous availability of food resources on landfill has facilitated year-round nest use in white storks and is influencing their home ranges and movement behaviour. White storks rely on landfill sites for foraging especially during the non-breeding season when other food resources are scarcer and this artificial food supplementation probably facilitated the establishment of resident populations. The closure of landfills, as required by EU Landfill Directives, will likely cause dramatic impacts on white stork populations

    Developing sustainability learning in business school curricula–productive boundary objects and participatory processes

    Full text link
    © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Sustainability learning is holistic and complex as it draws on diverse disciplines and can be interpreted differently within individual pedagogies. Embedding sustainability across and within business schools relies on developing suitable boundary objects. These may include representations such as models, frameworks or classificatory schemes that are malleable enough to be adapted for use within the disparate disciplines and pedagogies, yet durable enough to be recognisable and to maintain consistency across them. Boundary objects thus allow the sharing of ways of knowing or practice across various social boundaries. This paper outlines how participatory curriculum development processes can enable sustainability to be embedded in a business school curriculum. Distinct phases of the process were marked by different ways of knowing, as disciplinary-specific academics developed and embedded sustainability into and across curricula. Boundary objects were both outcomes and productive facilitators of this process. They acted as catalysts and attracted ongoing processes of dialogue, debate and meaning-making between these academics. The institutional context provided enabling conditions to legitimize outcomes from the participatory process. The process may be replicable in other business schools by the use of boundary objects

    The MeerKAT Galaxy Clusters Legacy Survey: star formation in massive clusters at 0.15 < z < 0.35

    Full text link
    We investigate dust-unbiased star formation rates (SFR) as a function of the environment in 20 massive clusters (M200>4×1014M⊙M_{200}>4\times10^{14} {\rm M}_{\odot}) between 0.15<z<0.350.15<z<0.35 using radio luminosities (L1.4GHzL_{\rm 1.4GHz}) from the recently released MeerKAT Galaxy Cluster Legacy Survey catalogue. We use optical data from the Dark Energy Camera Legacy Survey to estimate photo-zzs and assign cluster membership. We observe a steady decline in the fraction (fSFf_{\rm SF}) of star-forming galaxies from 2R2002R_{200} to the cluster centres in our full cluster sample, but notice a significant difference in fSFf_{\rm SF} gradients between clusters hosting large-scale extended radio emission in the form of haloes and relics (associated with ongoing merger activity) and non-radio-halo/relic hosting clusters. For star-forming galaxies within R200R_{200}, the fSFf_{\rm SF} in clusters hosting radio haloes and relics (0.148±0.0160.148\pm0.016) is ≈23%\approx23\% higher than in non-radio-halo/relic hosting clusters (0.120±0.0110.120\pm0.011). We observe a 3σ3\sigma difference between the total SFR normalised by cluster mass for non-radio-halo/relic hosting clusters (21.5±1.921.5\pm1.9 M⊙_{\odot}yr−1^{-1}/101410^{14}M⊙_{\odot}) and for clusters with radio haloes and relics (26.1±1.426.1\pm1.4 M⊙_{\odot}yr−1^{-1}/101410^{14}M⊙_{\odot}). There is a ≈4×\approx4\times decline in the mass normalised total SFR of clusters for galaxies with SFR above the luminous infrared galaxies (LIRGs) SFR limit at our redshift slice, corresponding to 2 Gyr in look-back time. This is consistent with the rapid decline in SF activity with decreasing redshift amongst cluster LIRGs seen by previous studies using infrared-derived SFR.Comment: 13 pages, 9 figures. To be published in MNRA

    The Curious Case of the “Heartworm” Nebula

    Get PDF
    © 2022. The Author(s). Published by the American Astronomical Society. This work is licensed under the terms of the Creative Commons Attribution 4.0 licence. https://creativecommons.org/licenses/by/4.0/The curious Galactic features near G357.2−0.2 were observed with the MeerKAT radio interferometer array in the UHF and L bands (0.56–1.68 GHz). There are two possibly related features: a newly identified faint heart-shaped partial shell (the “heart”), and a series of previously known but now much better imaged narrow, curved features (the “worm”) interior to the heart. Polarized emission suggests that much of the emission is nonthermal and is embedded in a dense plasma. The filaments of the worm appear to be magnetic structures powered by embedded knots that are sites of particle acceleration. The morphology of the worm broadly resembles some known pulsar wind nebulae (PWNe) but there is no known pulsar or PWN which could be powering this structure. We also present eROSITA observations of the field; no part of the nebula is detected in X-rays, but the current limits do not preclude the existence of a pulsar/PWN of intermediate spin-down luminosity.Peer reviewe

    Monitoring of dabigatran anticoagulation and its reversal in vitro by thrombelastography.

    Get PDF
    Dabigatran etexilate, a pro-drug of a direct thrombin inhibitor, was approved a few years ago for non-valvular atrial fibrillation and deep venous thrombosis. Rapid monitoring of the dabigatran level is essential in trauma and bleeding patients but the traditional plasma-based assays may not sufficiently display the effect. Furthermore, no antidote exists and reversal of the anticoagulant effect is impossible or difficult. The present study investigated the in vitro effect of dabigatran on whole blood thromboelastography (TEG) and its reversal by recombinant activated factor VII and prothrombin complex concentrate
    • 

    corecore