1,459 research outputs found
Proposição de requisitos para provimento de cargos comissionados: um estudo na Justiça Eleitoral - Caso TRE-ES
O presente estudo propõe critérios para as nomeações de cargos em comissão, em especial por aqueles sem vínculo com a instituição, em correlação com níveis de motivação dos servidores públicos efetivos do TRE-ES. Para tanto, foram analisados os resultados da última pesquisa de clima organizacional realizada em 2015, bem como as práticas e inovações que estão sendo implementadas em razão de inovações legais e normativas, em consonância com os princípios constitucionais da impessoalidade e eficiência. De posse do resultado desta análise, foram desenvolvidos argumentos para propor requisitos mínimos para a definição dos profissionais a ocuparem tais cargos, através de um instrumento normativo, permitindo que tais nomeações sejam melhor legitimadas aos olhos dos demais colaboradores e da sociedade em geral. Por fim, buscou formular preceitos de um programa permanente de identificação de novas lideranças dentre os servidores efetivos, potencializado com cursos de formação e atualizações procedimentais na área de gestão, com o objetivo de buscar perfis profissionais alinhados com as mais modernas técnicas de gestão pública
Gene and miR Expression in the Yellow Fever Mosquito Aedes aegypti
When animals are exposed to new conditions they need to tune the expression of hundreds of genes in specific tissues and at a specific time requires the interplay of multiple processes. Females are required to locate suitable oviposition sites after acquiring a blood meal. Mosquitoes possess a variety of genes responsible for chemosensation, with four families standing out: Olfaction Receptors (ORs), Ionotropic Receptors (IRs), Odorant Binding Proteins (OBPs), and Gustatory Receptors (GRs). To investigate the genes that may be involved in host seeking behavior, mRNA was sequenced from samples of A. aegypti male and female tissues using RNA-seq analysis. Simultaneously, small RNA was isolated and sequenced. MicroRNAs (miRs) can regulate genes post-transcriptionally and are thought to be important for olfaction gene regulation in the antenna of mosquitoes. Or46 and Or99 are expressed only in unfed females, while Or49 is only expressed post blood meal. A total of 14 IRs, 6 ORs and 6 OBPs are up regulated post feeding, while 8 IRs, 4 ORs and 11 OBPs are down regulated post feeding. A total of 16 new miRs were discovered in the antenna of females. miR-34, miR-79, miR-929, and miR-965 are uniquely expressed in the female antenna; while miR-92b is uniquely expressed in male antenna, while miR-279 is up regulated in the antenna of both males and females. The expression of the miR-275, which is associated with blood meal digestion, increases 3h after blood feeding in the head and thorax and miR-305 displays a similar expression pattern. This is the first study to find miRs that are uniquely expressed in the antenna of mosquitoes. Although there are differences in the expression of olfaction genes in the antenna of 12h old females and 4-day-old females, no changes are observed after blood feeding and similar observations were noted for miRs. Changes may occur only in a specific subset of sensory neurons in the antenna of females and for this reason could not be detected. Olfaction transcripts with long 3’UTR may compete for miRs binding and gene regulation in the antenna of mosquitoes without dramatic changes at the transcript level
Caracterização química de azeites elementares da região de Trás-os-Montes.
Trás-os-Montes é uma das principais regiões produtoras de azeite a nível nacional, onde é produzido azeite com a Denominação de Origem Protegida “Azeite de Trás-os-Montes”. De uma forma geral, estes azeites resultam de uma mistura de diferentes cultivares, maioritariamente Cobrançosa, Madural e Verdeal Transmontana, sendo permitida a presença de outras, ainda que em menor proporção.
Com o presente trabalho pretendeu-se contribuir para a caracterização química de azeites elementares produzidos na região de Trás-os-Montes. Assim, foram analisadas 80 amostras de azeite das cultivares Cobrançosa (20), Verdeal Transmontana (11), Madural (11), Santulhana (11), Negrinha de Freixo (11), Cordovil (10), Borrenta (2), Bical (1), Cordovesa (1), Lentisca (1) e Madural Negra (1), num total de 11 cultivares, tendo sido caracterizados no que respeita à acidez, índice de peróxidos, absorvência no ultravioleta, teor em clorofilas e carotenóides e composição em ácidos gordos
Eficacia analgésica del diclofenaco sódico vs. ibuprofeno después de la extracción quirúrgica de un tercer molar inferior incluido
-Objetivo: En este estudio evaluamos la eficacia analgésica
del diclofenaco sódico en comparación con el ibuprofeno,
después de la extracción quirúrgica de un tercer molar inferior
incluido.
-Diseño de estudio: Los pacientes que participaron en el estudio
fueron distribuidos de forma aleatoria en dos grupos. Uno fue
el grupo ibuprofeno y el otro el grupo diclofenaco. La intervención
practicada fue la extracción quirúrgica de un tercer molar
inferior cuya dificultad fue determinada en función del grado
de inclusión en todos los pacientes. Las variables registradas
fueron la intensidad del dolor y la necesidad de medicación
de rescate durante un periodo de una semana. Los registros se
realizaron una vez al día a la misma hora y registrados en un
cuaderno por parte del paciente.
-Resultados: Un total de 81 pacientes (87.1%) fueron incluidos
en el estudio. Los valores fueron similares en las primeras 48
horas postoperatorias, pero a partir del tercer día existió una
tendencia del grupo diclofenaco a mostrar valores de dolor
superiores, aunque sin llegar a existir diferencias estadísticamente
significativas (p>0.05). Esta tendencia a presentar mayor
dolor durante el periodo postoperatorio en el grupo diclofenaco
también se vio reflejada en el requerimiento del analgésico de
rescate y en el número de comprimidos empleados.
-Conclusiones: No se evidenciaron diferencias estadísticamente
significativas en cuanto a la eficacia analgésica del diclofenaco
sódico respecto al ibuprofeno, aunque sí pudo observarse una
mayor tendencia hacia la necesidad de más medicación suplementaria
durante los 2 primeros días del postoperatorio en el
grupo diclofenaco pero sin adquirir significación estadística
(p>0.05).-Objective: An evaluation is made of the analgesic efficacy of
diclofenac sodium versus ibuprofen after impacted lower third
molar surgery.
-Study design: The patients were randomly assigned to one of
two groups (ibuprofen or diclofenac). The difficulty of third
molar surgery, performed under local anesthesia, was assessed
by the degree of inclusion involved. The recorded study variables
were pain intensity and the need for rescue medication during
one week. The recordings were made once a day at the same
time, using a patient-completed questionnaire.
-Results: Eighty-one patients were finally included in the study
(87.1%). The results were similar in the first 48 postoperative
hours in both groups, though on the third day the diclofenac
group tended to show higher pain scores ' the differences being
nonsignificant, however (p>0.05). This tendency was also
reflected by an increased need for rescue medication and the
consumption of a larger number of tablets in the diclofenac
group.
-Conclusions: There were no statistically significant differences
in analgesic efficacy between diclofenac sodium and ibuprofen,
though the former was associated with an increased need for
supplementary medication in the first two postoperative days
(p>0.05)
Morbidity of third molar extraction in patients between 12 and 18 years of age
Objetivo: El propósito de este estudio fue analizar la incidencia de complicaciones después de la extracción quirúrgica de los terceros molares en pacientes de 12 a 18 años de edad. Pacientes y método: Se realizó un estudio retrospectivo de 390 extracciones quirúgicas de terceros molares superiores e inferiores en 173 pacientes en edades comprendidas entre los 12 y 18 años de edad, intervenidos bajo anestesia locorregional en el año 2000 en el Máster de Cirugía Bucal e Implantología Bucofacial de la Universidad de Barcelona. Los pacientes fueron divididos en tres grupos (A: 12-14 años, B:15-16 años, C: 17-18 años). Se registró la edad y el sexo del paciente, el motivo de la extracción, el grado de desarrollo dentario, la posición, la angulación y la inclusión del tercer molar. Finalmente se valoró la asociación entre dichas variables y la aparición de complicaciones postoperatorias. Resultados: La mayoría de los pacientes intervenidos fueron del sexo femenino (66,9%), y el grupo de edad en la que se realizó el mayor número de extracciones (62,8%) fue en el grupo C (17-18 años). El principal motivo de extracción fue la indicación por parte del ortodoncista (40,5%), seguido por la indicación profiláctica (39,5%). La presencia de clínica fue el motivo de extracción en un 20% de los casos. Se observó una incidencia del 15,6% de complicaciones postoperatorias tras la extracción de 390 terceros molares. En el grupo A el riesgo de complicaciones fue de 17,4%, en el grupo B de 19% y en el grupo C de 13,7%. Todas las complicaciones fueron reversibles y de corta duración como el dolor y la inflamación persistente, la infección, el trismo y la equimosis. Se presentó un caso de parestesia del nervio dentario inferior y un caso de parestesia del nervio lingual que remitieron a los 2 meses y al mes respectivamente. Conclusiones: este estudio demuestra que no hay diferencias significativas en las complicaciones observadas entre los tres grupos de edad, y por lo general, éstas son leves y reversibles. Se observó una mayor tendencia de complicaciones en las mujeres y el porcentaje de complicaciones aumenta cuanto menor es el espacio disponible para la erupció
Máster de cirugía e implantología bucal de la Universidad de Barcelona
La Universidad de Barcelona ante la ausencia del título oficial homologado equivalente, y de acuerdo con las recomendaciones de la Unión Europea (Directivas Ill/D/114/4/82 y lll/D/1374/5/84), desde el curso académico 1989-1990 estableció un programa de especialización en Cirugía Bucal de tres años de duración, tras el cual se obtiene el título de Máster en Cirugía e Implantología Bucal. De acuerdo con la normativa comunitaria ( CEE/lll/13 74/5/84), la Cirugía Bucal es la parte de la Odontología que se ocupa del diagnóstico y tratamiento quirúrgico de las enfermedades, anomalías y lesiones de los dientes, de la boca, de los maxilares y de los tejidos adyacentes..
A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction.
Background: To evaluate the use of guided bone regeneration with xenograft to prevent periodontal defect in the distal aspect of the second molar after the surgical removal of the mandibular third molar.Material and Methods: Three electronic databases (Pubmed, Cochrane Library and Scopus) were searched in April 2020. Randomized clinical trials in non-smokers and healthy patients, with at least six months follow-up, comparing periodontal probing depth, clinical attachment level, alveolar bone level and adverse events were selected by two independent investigators. The risk of bias assessment of the selected studies was evaluated by means of the Cochrane Collaboration's Tool. Finally, a meta-analysis of the outcomes of interest was performed.Results: Despite 795 articles were found in the initial search, only three randomized controlled clinical trials were included. Pooled results favoured the use of the xenograft plus collagen membrane over the spontaneous healing in terms of periodontal probing depth gain (MD=2.36; 95% CI 0.69 to 4.03; P=0.005) and clinical attachment level gain (MD=2.52; 95% CI 0.96 to 4.09; P=0.002). No other statistically significant differences were found. Conclusions: Within the limitations of the present review, the xenograft plus collagen membrane exhibited better periodontal results than spontaneous healing without increasing postoperative complications. However, future well-designed studies with larger samples are required to confirm our result
Development of a Brazilian maize core collection
The aim of this study was to evaluate methods for developing a Brazilian maize core collection. For an initial survey of the active collection, passport information, as well as characterization and evaluation of accessions, were taken into consideration, these then being divided according to geographic region and kernel-type. Multiple sampling methods were evaluated. The strategy of constant sampling generated extensive alterations in extract accession frequency. The multivariate strategy with dispersion graphs and principal components associated with the Tocher method was considered efficient for identifying the most divergent genotypes. The multivariate strategy generated greater alterations in the variance of traits. The average number of traits revealed few modifications with the various sampling strategies used. Therefore, the active collection could be considered as possessing a satisfactory amount of information for most of its accessions. Moreover, the multivariate strategy generated modifications in the variance of the traits, independent of sampling intensity
Modeling the effects of climate and land use change on carbon and trace gas budgets over the Amazon Region using NASA satellite products.
Abstract ID: 14. Publicado também on-line
Neutrinos Confronting Large Extra Dimensions
We study neutrino physics in a model with one large extra dimension. We
assume the existence of two four-dimensional branes in the five-dimensional
space-time, one for the ordinary particles and the other one for mirror
particles, and we investigate neutrino masses and mixings in this scheme.
Comparison of experimental neutrino data with the predictions of the model
leads to various restrictions on the parameters of the model. For instance, the
size of the extra dimension, R, turns out to be bounded from below.
Cosmological considerations seem to favor a large R. The usual mixing schemes
proposed as solutions to the solar and atmospheric neutrino anomalies are
compatible with our model.Comment: 19 pages, LATEX, 4 figure
- …