4 research outputs found
Motor, cognitive and mobility deficits in 1000 geriatric patients : protocol of a quantitative observational study before and after routine clinical geriatric treatment – the ComOn-study
© The Author(s). 2020 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany).
Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters.
Discussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort.info:eu-repo/semantics/publishedVersio
Exercise Performance Is a Prognostic Indicator in Elderly Patients With Chronic Heart Failure - Application of Metabolic Exercise Cardiac Kidney Indexes Score
In patients with chronic heart failure (HF) the Metabolic Exercise Cardiac Kidney Indexes (MECKI) score, is a predictor of cardiovascular death and urgent heart transplantation. We investigated the relationship between age, exercise tolerance and the prognostic value of the MECKI score
Prognostic role of atrial fibrillation in patients affected by chronic heart failure. Data from the MECKI score research group
Atrial fibrillation (AF) is common in heart failure (HF). It is unclear whether AF has an independent prognostic role in HF. The aim of the present study was to assess the prognostic role of AF in HF patients with reduced ejection fraction (EF)
The metabolic exercise test data combined with Cardiac And Kidney Indexes (MECKI) score and prognosis in heart failure. A validation study
51The Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score is a prognostic model to identify heart failure (HF) patients at risk for cardiovascular mortality (CVM) and urgent heart transplantation (uHT) based on 6 routine clinical parameters: hemoglobin, sodium, kidney function by the Modification of Diet in Renal Disease (MDRD) equation, left ventricle ejection fraction (LVEF), percentage of predicted peak oxygen consumption (VO2) and VE/VCO2 slope.nonenoneCorrà , Ugo; Agostoni, Piergiuseppe; Giordano, Andrea; Cattadori, Gaia; Battaia, Elisa; La Gioia, Rocco; Scardovi, Angela B; Emdin, Michele; Metra, Marco; Sinagra, Gianfranco; Limongelli, Giuseppe; Raimondo, Rosa; Re, Federica; Guazzi, Marco; Belardinelli, Romualdo; Parati, Gianfranco; Magrì, Damiano; Fiorentini, Cesare; Cicoira, Mariantonietta; Salvioni, Elisabetta; Giovannardi, Marta; Veglia, Fabrizio; Mezzani, Alessandro; Scrutinio, Domenico; Di Lenarda, Andrea; Ricci, Roberto; Apostolo, Anna; Iorio, Anna Maria; Paolillo, Stefania; Palermo, Pietro; Contini, Mauro; Vassanelli, Corrado; Passino, Claudio; Giannuzzi, Pantaleo; Piepoli, Massimo F; Antonioli, Laura; Segurini, Chiara; Bertella, Erica; Farina, Stefania; Bovis, Francesca; Pietrucci, Francesca; Malfatto, Gabriella; Roselli, Teo; Buono, Andrea; Calabrò, Raffaele; De Maria, Renata; Santoro, Daniela; Campanale, Saba; Caputo, Domenica; Bertipaglia, Donatella; Berton, EmanuelaCorrà , Ugo; Agostoni, Piergiuseppe; Giordano, Andrea; Cattadori, Gaia; Battaia, Elisa; La Gioia, Rocco; Scardovi, Angela B; Emdin, Michele; Metra, Marco; Sinagra, Gianfranco; Limongelli, Giuseppe; Raimondo, Rosa; Re, Federica; Guazzi, Marco; Belardinelli, Romualdo; Parati, Gianfranco; Magrì, Damiano; Fiorentini, Cesare; Cicoira, Mariantonietta; Salvioni, Elisabetta; Giovannardi, Marta; Veglia, Fabrizio; Mezzani, Alessandro; Scrutinio, Domenico; Di Lenarda, Andrea; Ricci, Roberto; Apostolo, Anna; Iorio, Anna Maria; Paolillo, Stefania; Palermo, Pietro; Contini, Mauro; Vassanelli, Corrado; Passino, Claudio; Giannuzzi, Pantaleo; Piepoli, Massimo F; Antonioli, Laura; Segurini, Chiara; Bertella, Erica; Farina, Stefania; Bovis, Francesca; Pietrucci, Francesca; Malfatto, Gabriella; Roselli, Teo; Buono, Andrea; Calabrò, Raffaele; De Maria, Renata; Santoro, Daniela; Campanale, Saba; Caputo, Domenica; Bertipaglia, Donatella; Berton, Emanuel