2,091,352 research outputs found
Age-dependent sensitization to the 7S-vicilin-like protein Cor a 11 from hazelnut (Corylus avellana) in a birch-endemic region
Background: Hazelnut (Corylus avellana) allergy exhibits age and geographically distinct sensitization patterns that have not yet been fully resolved.
Objective: To study sensitization to Cor a 11 in different age groups of hazelnut-allergic patients and infants with atopic dermatitis (AD) sensitized to hazelnut in a birch-endemic region.
Methods: Sera from 80 hazelnut-allergic patients, 33 infants under 1 year of age with AD (24 sensitized and 9 not sensitized to hazelnut), 32 healthy control individuals, and 29 birch pollenâallergic but hazelnut-tolerant individuals were tested for immunoglobulin (Ig) E reactivity to Cor a 11 by ImmunoCAP. IgE reactivity to Cor a 1.01, Cor a 1.04, Cor a 8, and Cor a 9 was studied by ISAC microarray.
Results: Forty patients (22 preschool children, 10 schoolchildren, and 8 adults) with systemic reactions on consumption of hazelnut were sensitized to Cor a 11 (respective rates of 36%, 40%, and 12.5%). Forty patients (6 preschool children, 10 schoolchildren, and 24 adults) reported oral allergy syndrome but only 2 of them (of preschool age) were sensitized to Cor a 11. Two (8%) of the AD infants sensitized to hazelnut showed IgE reactivity to Cor a 11. This reactivity was not observed in any of the AD infants without sensitization to hazelnut, in any of the birch-pollen allergic patients without hazelnut allergy, or in any of the healthy control individuals.
Conclusion: Sensitization to Cor a 11 in a birch-endemic region is predominantly found in children with severe hazelnut allergy, a finding that is consistent with observations concerning sensitization to Cor a 9
Cor triatriatum sinister with situs inversus totalis in an infant.
Cor triatriatum sinister is a rare congenital cardiac malformation characterized by a membrane in
the left atrium which separates the left atrium into the proximal and distal chambers.Association of
cor triatriatum is extremely rare with situs inversus totalis. This article reports a rare case of cor
triatriatum sinister with situs inversus totalis in a 5 month old female infantpeer-reviewe
Coronatine Facilitates Pseudomonas syringae Infection of Arabidopsis Leaves at Night.
In many land plants, the stomatal pore opens during the day and closes during the night. Thus, periods of darkness could be effective in decreasing pathogen penetration into leaves through stomata, the primary sites for infection by many pathogens. Pseudomonas syringae pv. tomato (Pst) DC3000 produces coronatine (COR) and opens stomata, raising an intriguing question as to whether this is a virulence strategy to facilitate bacterial infection at night. In fact, we found that (a) biological concentration of COR is effective in opening dark-closed stomata of Arabidopsis thaliana leaves, (b) the COR defective mutant Pst DC3118 is less effective in infecting Arabidopsis in the dark than under light and this difference in infection is reduced with the wild type bacterium Pst DC3000, and (c) cma, a COR biosynthesis gene, is induced only when the bacterium is in contact with the leaf surface independent of the light conditions. These findings suggest that Pst DC3000 activates virulence factors at the pre-invasive phase of its life cycle to infect plants even when environmental conditions (such as darkness) favor stomatal immunity. This functional attribute of COR may provide epidemiological advantages for COR-producing bacteria on the leaf surface
Metrical theory for -Rosen fractions
The Rosen fractions form an infinite family which generalizes the
nearest-integer continued fractions. In this paper we introduce a new class of
continued fractions related to the Rosen fractions, the -Rosen
fractions. The metrical properties of these -Rosen fractions are
studied. We find planar natural extensions for the associated interval maps,
and show that these regions are closely related to similar region for the
'classical' Rosen fraction. This allows us to unify and generalize results of
diophantine approximation from the literature
The Simulation of the Inelastic Impact
The coefficient of normal restitution (COR) in an oblique impact is
theoretically studied. Using a two-dimensional lattice models for an elastic
disk and an elastic wall, we investigate the dependency of COR on an incident
angle and demonstrate that COR can exceed one and have a peak against an
incident angle in our simulation. Finally, we explain these phenomena based
upon the phenomenological theory of elasticity.Comment: 2 pages, 3 figures, submitted as the proceedings of the international
conference on slow dynamics in complex systems(Sendai, Nov.3-8, 2003
Entropy quotients and correct digits in number-theoretic expansions
Expansions that furnish increasingly good approximations to real numbers are
usually related to dynamical systems. Although comparing dynamical systems
seems difficult in general, Lochs was able in 1964 to relate the relative speed
of approximation of decimal and regular continued fraction expansions (almost
everywhere) to the quotient of the entropies of their dynamical systems. He
used detailed knowledge of the continued fraction operator. In 2001, a
generalization of Lochs' result was given by Dajani and Fieldsteel in
\citeDajF, describing the rate at which the digits of one number-theoretic
expansion determine those of another. Their proofs are based on covering
arguments and not on the dynamics of specific maps. In this paper we give a
dynamical proof for certain classes of transformations, and we describe
explicitly the distribution of the number of digits determined when comparing
two expansions in integer bases. Finally, using this generalization of Lochs'
result, we estimate the unknown entropy of certain number theoretic expansions
by comparing the speed of convergence with that of an expansion with known
entropy.Comment: Published at http://dx.doi.org/10.1214/074921706000000202 in the IMS
Lecture Notes--Monograph Series
(http://www.imstat.org/publications/lecnotes.htm) by the Institute of
Mathematical Statistics (http://www.imstat.org
An algebra of deformation quantization for star-exponentials on complex symplectic manifolds
The cotangent bundle to a complex manifold is classically endowed
with the sheaf of \cor-algebras \W[T^*X] of deformation quantization, where
\cor\eqdot \W[\rmptt] is a subfield of \C[[\hbar,\opb{\hbar}]. Here, we
construct a new sheaf of \cor-algebras \TW[T^*X] which contains \W[T^*X]
as a subalgebra and an extra central parameter . We give the symbol calculus
for this algebra and prove that quantized symplectic transformations operate on
it. If is any section of order zero of \W[T^*X], we show that
\exp(t\opb{\hbar} P) is well defined in \TW[T^*X].Comment: Latex file, 24 page
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