82 research outputs found
Is the evidence for dark energy secure?
Several kinds of astronomical observations, interpreted in the framework of
the standard Friedmann-Robertson-Walker cosmology, have indicated that our
universe is dominated by a Cosmological Constant. The dimming of distant Type
Ia supernovae suggests that the expansion rate is accelerating, as if driven by
vacuum energy, and this has been indirectly substantiated through studies of
angular anisotropies in the cosmic microwave background (CMB) and of spatial
correlations in the large-scale structure (LSS) of galaxies. However there is
no compelling direct evidence yet for (the dynamical effects of) dark energy.
The precision CMB data can be equally well fitted without dark energy if the
spectrum of primordial density fluctuations is not quite scale-free and if the
Hubble constant is lower globally than its locally measured value. The LSS data
can also be satisfactorily fitted if there is a small component of hot dark
matter, as would be provided by neutrinos of mass 0.5 eV. Although such an
Einstein-de Sitter model cannot explain the SNe Ia Hubble diagram or the
position of the `baryon acoustic oscillation' peak in the autocorrelation
function of galaxies, it may be possible to do so e.g. in an inhomogeneous
Lemaitre-Tolman-Bondi cosmology where we are located in a void which is
expanding faster than the average. Such alternatives may seem contrived but
this must be weighed against our lack of any fundamental understanding of the
inferred tiny energy scale of the dark energy. It may well be an artifact of an
oversimplified cosmological model, rather than having physical reality.Comment: 12 pages, 5 figures; to appear in a special issue of General
Relativity and Gravitation, eds. G.F.R. Ellis et al; Changes: references
reformatted in journal style - text unchange
LIMITS ON ANISOTROPY AND INHOMOGENEITY FROM THE COSMIC BACKGROUND RADIATION,
We consider directly the equations by which matter imposes anisotropies on
freely propagating background radiation, leading to a new way of using
anisotropy measurements to limit the deviations of the Universe from a
Friedmann-Robertson-Walker (FRW) geometry. This approach is complementary to
the usual Sachs-Wolfe approach: the limits obtained are not as detailed, but
they are more model-independent. We also give new results about combined
matter-radiation perturbations in an almost-FRW universe, and a new exact
solution of the linearised equations.Comment: 18 pages Latex
Statefinder and Om Diagnostics for Interacting New Holographic Dark Energy Model and Generalized Second Law of Thermodynamics
In this work, we have considered that the flat FRW universe is filled with
the mixture of dark matter and the new holographic dark energy. If there is an
interaction, we have investigated the natures of deceleration parameter,
statefinder and diagnostics. We have examined the validity of the first
and generalized second laws of thermodynamics under these interactions on the
event as well as apparent horizon. It has been observed that the first law is
violated on the event horizon. However, the generalized second law is valid
throughout the evolution of the universe enveloped by the apparent horizon.
When the event horizon is considered as the enveloping horizon, the generalized
second law is found to break down excepting at late stage of the universe.Comment: 9 pages, 13 figure
Running coupling: Does the coupling between dark energy and dark matter change sign during the cosmological evolution?
In this paper we put forward a running coupling scenario for describing the
interaction between dark energy and dark matter. The dark sector interaction in
our scenario is free of the assumption that the interaction term is
proportional to the Hubble expansion rate and the energy densities of dark
sectors. We only use a time-variable coupling (with the scale factor
of the universe) to characterize the interaction . We propose a
parametrization form for the running coupling in which the
early-time coupling is given by a constant , while today the coupling is
given by another constant, . For investigating the feature of the running
coupling, we employ three dark energy models, namely, the cosmological constant
model (), the constant model (), and the time-dependent
model (). We constrain the models with the current
observational data, including the type Ia supernova, the baryon acoustic
oscillation, the cosmic microwave background, the Hubble expansion rate, and
the X-ray gas mass fraction data. The fitting results indicate that a
time-varying vacuum scenario is favored, in which the coupling crosses
the noninteracting line () during the cosmological evolution and the sign
changes from negative to positive. The crossing of the noninteracting line
happens at around , and the crossing behavior is favored at about
1 confidence level. Our work implies that we should pay more attention
to the time-varying vacuum model and seriously consider the phenomenological
construction of a sign-changeable or oscillatory interaction between dark
sectors.Comment: 8 pages, 5 figures; refs added; to appear in EPJ
Dark energy as a mirage
Motivated by the observed cosmic matter distribution, we present the
following conjecture: due to the formation of voids and opaque structures, the
average matter density on the path of the light from the well-observed objects
changes from Omega_M ~ 1 in the homogeneous early universe to Omega_M ~ 0 in
the clumpy late universe, so that the average expansion rate increases along
our line of sight from EdS expansion Ht ~ 2/3 at high redshifts to free
expansion Ht ~ 1 at low redshifts. To calculate the modified observable
distance-redshift relations, we introduce a generalized Dyer-Roeder method that
allows for two crucial physical properties of the universe: inhomogeneities in
the expansion rate and the growth of the nonlinear structures. By treating the
transition redshift to the void-dominated era as a free parameter, we find a
phenomenological fit to the observations from the CMB anisotropy, the position
of the baryon oscillation peak, the magnitude-redshift relations of type Ia
supernovae, the local Hubble flow and the nucleosynthesis, resulting in a
concordant model of the universe with 90% dark matter, 10% baryons, no dark
energy, 15 Gyr as the age of the universe and a natural value for the
transition redshift z_0=0.35. Unlike a large local void, the model respects the
cosmological principle, further offering an explanation for the late onset of
the perceived acceleration as a consequence of the forming nonlinear
structures. Additional tests, such as quantitative predictions for angular
deviations due to an anisotropic void distribution and a theoretical derivation
of the model, can vindicate or falsify the interpretation that light
propagation in voids is responsible for the perceived acceleration.Comment: 33 pages, 2 figs; v2: minor clarifications, results unchanged; v3:
matches the version published in General Relativity and Gravitatio
Leptogenesis and rescattering in supersymmetric models
The observed baryon asymmetry of the Universe can be due to the
violating decay of heavy right handed (s)neutrinos. The amount of the asymmetry
depends crucially on their number density. If the (s)neutrinos are generated
thermally, in supersymmetric models there is limited parameter space leading to
enough baryons. For this reason, several alternative mechanisms have been
proposed. We discuss the nonperturbative production of sneutrino quanta by a
direct coupling to the inflaton. This production dominates over the
corresponding creation of neutrinos, and it can easily (i.e. even for a rather
small inflaton-sneutrino coupling) lead to a sufficient baryon asymmetry. We
then study the amplification of MSSM degrees of freedom, via their coupling to
the sneutrinos, during the rescattering phase which follows the nonperturbative
production. This process, which mainly influences the (MSSM) flat
directions, is very efficient as long as the sneutrinos quanta are in the
relativistic regime. The rapid amplification of the light degrees of freedom
may potentially lead to a gravitino problem. We estimate the gravitino
production by means of a perturbative calculation, discussing the regime in
which we expect it to be reliable.Comment: (20 pages, 6 figures), references added, typos corrected. Final
version in revte
Modified Chaplygin Gas as a Unified Dark Matter and Dark Energy Model and Cosmic Constraints
A modified Chaplygin gas model (MCG),
,
as a unified dark matter model and dark energy model is constrained by using
current available cosmic observational data points which include type Ia
supernovae, baryon acoustic oscillation and the seventh year full WMAP data
points. As a contrast to the consideration in the literatures, we {\it do not}
separate the MCG into two components, i.e. dark mater and dark energy
component, but we take it as a whole energy component-a unified dark sector. By
using Markov Chain Monte Carlo method, a tight constraint is obtained: , and .}Comment: 6 pages, 3 figure
Multi-system neurological disease is common in patients with OPA1 mutations
Additional neurological features have recently been described in seven families transmitting pathogenic mutations in OPA1, the most common cause of autosomal dominant optic atrophy. However, the frequency of these syndromal âdominant optic atrophy plusâ variants and the extent of neurological involvement have not been established. In this large multi-centre study of 104 patients from 45 independent families, including 60 new cases, we show that extra-ocular neurological complications are common in OPA1 disease, and affect up to 20% of all mutational carriers. Bilateral sensorineural deafness beginning in late childhood and early adulthood was a prominent manifestation, followed by a combination of ataxia, myopathy, peripheral neuropathy and progressive external ophthalmoplegia from the third decade of life onwards. We also identified novel clinical presentations with spastic paraparesis mimicking hereditary spastic paraplegia, and a multiple sclerosis-like illness. In contrast to initial reports, multi-system neurological disease was associated with all mutational subtypes, although there was an increased risk with missense mutations [odds ratio = 3.06, 95% confidence interval = 1.44â6.49; P = 0.0027], and mutations located within the guanosine triphosphate-ase region (odds ratio = 2.29, 95% confidence interval = 1.08â4.82; P = 0.0271). Histochemical and molecular characterization of skeletal muscle biopsies revealed the presence of cytochrome c oxidase-deficient fibres and multiple mitochondrial DNA deletions in the majority of patients harbouring OPA1 mutations, even in those with isolated optic nerve involvement. However, the cytochrome c oxidase-deficient load was over four times higher in the dominant optic atrophy + group compared to the pure optic neuropathy group, implicating a causal role for these secondary mitochondrial DNA defects in disease pathophysiology. Individuals with dominant optic atrophy plus phenotypes also had significantly worse visual outcomes, and careful surveillance is therefore mandatory to optimize the detection and management of neurological disability in a group of patients who already have significant visual impairment
Cosmic acceleration and phantom crossing in -gravity
In this paper, we propose two new models in gravity to realize
universe acceleration and phantom crossing due to dark torsion in the
formalism. The model parameters are constrained and the observational test are
discussed. The best fit results favors an accelerating universe with possible
phantom crossing in the near past or future followed respectively by matter and
radiation dominated era.Comment: 20 pages, 18 figures, Will appear in Astrophys Space Sc
Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)
BACKGROUND:
Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.
METHODS:
Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights.
FINDINGS:
5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease.
INTERPRETATION:
International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems
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