Axial-vector meson mixing in orthocharmonium decays

The new BES measurement on the two-body decays of J/psi and psi' into an axial-vector meson and a pseudoscalar meson is analyzed with the axial-K mixing including the one-photon annihilation contribution. A somewhat puzzling pattern of the K_1^+ K^- decay channels can be understood with no tight constraint on the mixing angle. The branching fractions of the K_1^0 K-bar^0 channels will be the cleanest source of information to determine the mixing angle from the 1^+ 0^- decays of J/psi and psi'.Comment: 14 pages with 4 eps figure

A possible hadronic excess in psi(2S) decay and rho-pi puzzle

We examine the so-called rho-pi puzzle of the psi(2S) decay by incorporating two inputs: One is the relative phase between the one-photon and the gluon decay amplitude, and the other is a possible anomaly in the inclusive nonelectromagnetic decay rate of psi(2S). We propose the possibility that in the psi(2S) decay a hadronic decay process of long distance origin is important in addition to the short-distance decay process. The amplitude of this additional process should nearly cancel the three-gluon amplitude in the exclusive psi(2S)---> 1-0- and turn the sum dominantly real in contrast to the J/psi decay. We present general consequences of this mechanism and then briefly look into two models which possibly explain the course of this additional amplitude.Comment: 14 pages, 2 Tables, and 3 eps figures. Replaces the original version with a minor change in the title and inclusion of more references. The version to appear in Phys. Rev.

Constraint on axial-vector meson mixing angle from nonrelativistic constituent quark model

In a nonrelativistic constituent quark model we find a constraint on the mixing angle of the strange axial-vector mesons, $35^o\stackrel{<}{\sim } \theta _K\stackrel{<}{\sim }55^o,$ determined solely by two parameters: the mass difference of the $a_1$ and $b_1$ mesons and the ratio of the constituent quark masses.Comment: 8 pages, LaTe

A Global Network of Science and Technology Advice in Foreign Ministries

This paper is a product of the International Dialogue on Science and Technology Advice in Foreign Ministries (Vienna Dialogue) in October 2016, involving more than twenty nations and several international organisations. The event was a key step to further develop the Foreign Minister Science and Technology Advisor Network (FMSTAN), growing from an initial group of five nations. The Vienna Dialogue was convened by the Fletcher School of Law and Diplomacy, Tufts University, and the International Institute for Applied Systems Analysis (IIASA) at the Vienna headquarters of IIASA, bringing together diplomats from foreign ministries to consider the value of evidence for informed decision-making by nations with regard to issues, impacts and resources within, across and beyond national boundaries. The evidence comes from the natural and social sciences with engineering and medicine as well as other areas of technology. By building common interests among nations, science is a tool of diplomacy, promoting cooperation and preventing conflict in our world. Science diplomacy was discussed as an international, interdisciplinary and inclusive process to help balance national interests and common interests in view of urgencies today and across generations in our globally-interconnected civilization

Towards resolution of the enigmas of P-wave meson spectroscopy

The mass spectrum of P-wave mesons is considered in a nonrelativistic constituent quark model. The results show the common mass degeneracy of the isovector and isodoublet states of the scalar and tensor meson nonets, and do not exclude the possibility of a similar degeneracy of the same states of the axial-vector and pseudovector nonets. Current experimental hadronic and \tau -decay data suggest, however, a different scenario leading to the a_1 meson mass \simeq 1190 MeV and the K_{1A}-K_{1B} mixing angle \simeq (37\pm 3)^o. Possible s\bar{s} states of the four nonets are also discussed.Comment: 22 pages, LaTe

Sustainable development discourse in Smart Specialization Strategies

Smart Specialization Strategies have been used to implement European Union Cohesion Policy in recent years, aiming to achieve economic, social and territorial development by reducing disparities between regions. The European Union often declares an alignment between Cohesion Policy, Smart Specialization Strategies and the United Nations Agenda 2030. However, and despite the recurrent Sustainable Development discourse present in the European political agenda, it is not evident that Smart Specialization Strategies integrate Sustainable Development goals and practices. Hence, this paper aims to explore and discuss the degree of embeddedness of the Sustainable Development discourse in the Research and Innovation Strategies for Smart Specialization, using the Portuguese Centro Region as an exploratory study. In this research a content analysis of the Centro Region Smart Specialization Strategy was used for data collection and analysis, framed by the 17 goals of Agenda 2030 and their targets. Results show a good embeddedness of the overall goals of Agenda 2030, but a lower integration of the targets, suggesting that this strategy needs to be revisited to further integrate Agenda 2030. Moreover, the Centro Smart Specialization Strategy has a strong alignment with the goals related with economic and environmental issues, almost disregarding social aspects. These findings are amplified by the fact that this strategy is mainly being implemented through projects financed under the economy pillar. Finally, there is evidence about the need of developing regional innovation policies towards sustainable development from the regional to the national level. Overall, it is critical to enlarge the debate on how Smart Specialization Strategies can be an effective engine for a new development trajectory for European regions assuming the Agenda 2030 as a framework for the necessary change.publishe

Biallelic variants of ATP13A3 cause dose-dependent childhood-onset pulmonary arterial hypertension characterised by extreme morbidity and mortality.

BACKGROUND: The molecular genetic basis of pulmonary arterial hypertension (PAH) is heterogeneous, with at least 26 genes displaying putative evidence for disease causality. Heterozygous variants in the ATP13A3 gene were recently identified as a new cause of adult-onset PAH. However, the contribution of ATP13A3 risk alleles to child-onset PAH remains largely unexplored. METHODS AND RESULTS: We report three families with a novel, autosomal recessive form of childhood-onset PAH due to biallelic ATP13A3 variants. Disease onset ranged from birth to 2.5 years and was characterised by high mortality. Using genome sequencing of parent-offspring trios, we identified a homozygous missense variant in one case, which was subsequently confirmed to cosegregate with disease in an affected sibling. Independently, compound heterozygous variants in ATP13A3 were identified in two affected siblings and in an unrelated third family. The variants included three loss of function variants (two frameshift, one nonsense) and two highly conserved missense substitutions located in the catalytic phosphorylation domain. The children were largely refractory to treatment and four died in early childhood. All parents were heterozygous for the variants and asymptomatic. CONCLUSION: Our findings support biallelic predicted deleterious ATP13A3 variants in autosomal recessive, childhood-onset PAH, indicating likely semidominant dose-dependent inheritance for this gene

A study of the reaction pim p --> omega pim p at 18 GeV/c: The D and S decay amplitudes for b1(1235) --> omega pi

The reaction pim p --> omega pim p, omega --> pip pim pi0 has been studied at 18 GeV/c. The omega pim mass spectrum is found to be dominated by the b1(1235). Partial Wave Analysis shows that b1 production is dominated by natural parity exchange. The S-wave and D-wave amplitudes for b1(1235) --> omega pi have been determined, and it is found that the amplitude ratio, |D/S| = 0.269 +/- (0.009)stat +/- (0.01)sys and the phase difference, phi(D-S) = 10.54 deg +/- (2.4)stat +/- (3.9)sys.Comment: 7 pages, 9 figures, revtex4 format, to be published in Physics Letters

Innovations for Sustainability: Pathways to an efficient and post-pandemic future

3rd Report prepared by The World in 2050 initiativ