A Rare Cause of Abdominal Pain in a Patient with Acute Necrotizing Pancreatitis.

INTRODUCTION: Walled-off necrosis (WON) is a potentially lethal late complication of acute pancreatitis (AP) and occurs in less than 10% of AP cases. It can be located in or outside the pancreas. When infected, the mortality rate increases and can reach 100% if the collection is not drained. Its treatment is complex and includes, at the beginning, intravenous antibiotics, which permit sepsis control and a delay in the therapeutic intervention, like drainage. Nowadays, a minimally invasive approach is advised. Depending on the location of the collection, computed tomography (CT)-guided drainage or endoscopic necrosectomy are the primary options, then complemented by surgical necrosectomy if needed. Infected WON of the abdominal wall has been rarely described in the literature and there is no report of any infection with Citrobacter freundii. CASE: We present the case of a 61-year-old man with necrotizing AP complicated by WON of the left abdominal wall, infected with Citrobacter freundii that was successfully treated with CT-guided percutaneous drainage and intravenous antibiotics. CONCLUSION: Infected WON accounts for considerable mortality and its location in the abdominal wall is rare; it can be treated with antibiotics and CT-guided drainage with no need for further intervention.info:eu-repo/semantics/publishedVersio

T-Life: um programa de treino da capacidade de reconhecimento emocional em pessoas com perturbações do espectro autista

Os indivíduos com défices de relacionamento interpessoal, especificamente com Perturbação do Espectro Autista (PEA), apresentam dificuldades em reconhecer emoções em si e nos outros, evidenciando claro prejuízo no funcionamento social e tarefas interpessoais do quotidiano. O Reconhecimento das Expressões Faciais (REF) tem sido estudado na tentativa de compreensão dos défices no reconhecimento emocional. Inúmeros trabalhos tentam promover o reconhecimento emocional facial em indivíduos com PEA, mas não através da síntese da face em tempo real. As novas tecnologias, nomeadamente a Realidade Virtual, parecem ser muito promissoras no trabalho com as PEA (Eynon, 1997, cit. in Beardon et al., 2001; Strickland et al., 1996), pois vão ao encontro das necessidades/características destes indivíduos ao permitirem: o controlo na apresentação dos estímulos; a introdução de modificações graduais para permitir a generalização; a garantia de situações seguras de aprendizagem, a intervenção individualizada e customizada e a interacção com computadores, factor motivador que permite a aprendizagem de forma não ansiogénica (Strickland, 1997). A abordagem que estamos a desenvolver e a testar reflecte todos estes pressupostos e enquadra-se numa tipologia de jogo. What a feeling é um videojogo que apresenta como finalidade melhorar a capacidade de indivíduos, social e emocionalmente diminuídos, no reconhecimento de emoções através da expressão facial. O jogo desenvolvido permite, através de um conjunto de exercícios, que qualquer pessoa de qualquer idade possa interagir com modelos 3D e aprender sobre as expressões da face. O jogo é baseado em síntese facial em tempo real. Nesta comunicação descreveremos a mecânica da nossa metodologia de aprendizagem e apresentaremos algumas linhas de orientação para trabalho futuro, resultante dos estudos desenvolvidos com os protótipos testados

Trauma quality indicators: internationally approved core factors for trauma management quality evaluation

ntroduction: Quality in medical care must be measured in order to be improved. Trauma management is part of health care, and by definition, it must be checked constantly. The only way to measure quality and outcomes is to systematically accrue data and analyze them. Material and methods: A systematic revision of the literature about quality indicators in trauma associated to an international consensus conference Results: An internationally approved base core set of 82 trauma quality indicators was obtained: Indicators were divided into 6 fields: prevention, structure, process, outcome, post-traumatic management, and society integrational effects. Conclusion: Present trauma quality indicator core set represents the result of an international effort aiming to provide a useful tool in quality evaluation and improvement. Further improvement may only be possible through international trauma registry development. This will allow for huge international data accrual permitting to evaluate results and compare outcomes

The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation

<p>Abstract</p> <p>Background</p> <p>This study evaluated the relationship between ulcerative colitis and obesity, which are both chronic diseases characterized by inflammation and increases in immune cells and pro-inflammatory cytokines.</p> <p>Methods</p> <p>Mice with chronic ulcerative colitis induced by 2 cycles of dextran sodium sulfate (DSS) in the first and fourth week of the experiment were fed a high-fat diet (HFD) to induce obesity by 8 weeks. The animals were divided into 4 groups (control, colitis, HFD and colitis + HFD).</p> <p>Results</p> <p>Obesity alone did not raise histopathology scores, but the combination of obesity and colitis worsened the scores in the colon compared to colitis group. Despite the reduction in weight gain, there was increased inflammatory infiltrate in both the colon and visceral adipose tissue of colitis + HFD mice due to increased infiltration of macrophages, neutrophils and lymphocytes. Intravital microscopy of VAT microvasculature showed an increase in leukocyte adhesion and rolling and overexpression of adhesion molecules compared to other groups. Moreover, circulating lymphocytes, monocytes and neutrophils in the spleen and cecal lymph nodes were increased in the colitis + HFD group.</p> <p>Conclusion</p> <p>Our results demonstrated the relationship between ulcerative colitis and obesity as aggravating factors for each disease, with increased inflammation in the colon and adipose tissue and systemic alterations observed in the spleen, lymph nodes and bloodstream.</p

Estudos epidemiológicos entre grupos indígenas de Rondônia: IV. Inquérito sorológico para rotavírus entre os Suruí e Karitiána

The authors present the results of a sero-epidemiological survey for rotavirus antibodies conducted among the Suruí and Kantiána, two amerindian groups of Rondônia, Brazilian Amazonia. The results indicate high percentages of seropositivity for both groups (67.8% among the Surui and 77.4% among the Kantiana using ELISA and 45.5% for the Suruí and 56.7% for the Karitiána using indirect immunofluorescence). Chi square tests indicated no statistically significant association between group and seropositivity. The results are discussed in the light of other studies conducted among Brazilian amerindian groups.São apresentados os dados de um inquérito soro epidemiológico para anticorpos anti-rotavírus conduzido entre os Suruí e Karitiána, dois grupos indígenas de Rondônia, Brasil. Os resultados indicam que as porcentagens de soropositividade são elevadas (67,8% para os Suruí e 77,4% para os Karitiána, através da técnica ELISA, e 45,5% para os Suruí e 56,7% para os Karitiána, através de imunofluorescência indireta). Testes de qui-quadrado indicam não haver associação estatisticamente significante entre grupo e positividade sorológica. São discutidos os resultados à luz de outros estudos conduzidos com grupos indígenas brasileiros

Could the variation in quasar luminosity, due to extra dimension 3-brane in RS model, be measurable?

We propose an alternative theoretical approach showing how the existence of an extra dimension in RS model can estimate the correction in the Schwarzschild radius of black holes, and consequently its measurability in terms of the variation of quasar luminosity, which can be caused by a imprint of an extra dimension endowing the geometry of a brane-world scenario in an AdS_5 bulk. This paper is intended to investigate the variation of luminosity due to accretion of gas in black holes (BHs) in the center of quasars, besides also investigating the variation of luminosity in supermassive BHs by brane-world effects, using RS model.Comment: Revtex4, 7 Pages, 6 Figures, v2 has minor change