197 research outputs found
Recommended from our members
Enantioselective organocatalytic synthesis of bicyclic resorcinols via an intramolecular Friedel-Crafts-type 1,4-addition: access to cannabidiol analogues
The organocatalytic transformation of resorcinols is extremely rare. In this article, we report a highly enantioselective, organocatalytic intramolecular cyclization of these systems by a FriedelâCrafts-type 1,4-addition using a JĂžrgensen-Hayashi-like organocatalyst with a large silyl protecting group, and show that heat improves reaction yield with virtually no detriment to enantioselectivity. A variety of bicyclic resorcinols were obtained with excellent enantioselectivities (up to 94%). To show the utility of these constructs, and as part of a wider project involving the synthesis of cannabinoid-like compounds, the resorcinol formed was used to generate both ânormalâ and âabnormalâ cannabidiol (CBD) derivatives which were shown to have anticonvulsant activity
Morphology and foliar chemistry of containerized Abies fraseri (Pursh) Poir. seedlings as affected by water availability and nutrition
âą We present the results of a two-year (2007â2008) greenhouse study investigating the
effect of water availability and nitrogen fertilization on the growth, biomass
partitioning, and foliar nutrient content of Abies fraseri (Pursh)
Poir.
âą Fertilizer and moisture content (irrigation) were varied in a factorial experiment
combining four levels of irrigation and three levels of fertilization to evaluate growth
and foliar nutrient content. In addition, a numerical optimization was used to estimate
appropriate levels of each factor necessary to achieve simulated goals for response
variables.
âą Irrigation increased the height growth by 12 to 35% depending on the fertilization
treatment (p = 0.0001). Fertilization increased height growth by 10 to
26% (p = 0.02). A similar response was observed for stem diameter growth
(SDG). Total biomass accumulation increased as result of positive response of stem and
root biomass development, and foliar nitrogen content was positively affected by nitrogen
fertilization and negatively affected by irrigation. The numerical optimization for
simulated target growth and nitrogen content responses produced levels of input
combinations with high desirability factors to achieve the target responses.
âą These results suggest that nutrient addition is a strong determining factor for early
development of this species. The improved growth efficiency in this study is likely
attributed to a combination of factors including, improved photosynthetic capacity,
decreased stomatal limitations, or increased resource allocation to stems
Multimessenger astronomy with the Einstein Telescope
Gravitational waves (GWs) are expected to play a crucial role in the
development of multimessenger astrophysics. The combination of GW observations
with other astrophysical triggers, such as from gamma-ray and X-ray satellites,
optical/radio telescopes, and neutrino detectors allows us to decipher science
that would otherwise be inaccessible. In this paper, we provide a broad review
from the multimessenger perspective of the science reach offered by the third
generation interferometric GW detectors and by the Einstein Telescope (ET) in
particular. We focus on cosmic transients, and base our estimates on the
results obtained by ET's predecessors GEO, LIGO, and Virgo.Comment: 26 pages. 3 figures. Special issue of GRG on the Einstein Telescope.
Minor corrections include
A multi-species synthesis of physiological mechanisms in drought-induced tree mortality
Widespread tree mortality associated with drought 92 has been observed on all forested continents, and global change is expected to exacerbate vegetation vulnerability. Forest mortality has implications for future biosphere-atmosphere interactions of carbon, water, and energy balance, and is poorly represented in dynamic vegetation models. Reducing uncertainty requires improved mortality projections founded on robust physiological processes. However, the proposed mechanisms of drought-induced mortality, including hydraulic failure and carbon starvation, are unresolved. A growing number of empirical studies have investigated these mechanisms, but data have not been consistently analyzed across species and biomes using a standardized physiological framework. Here we show that xylem hydraulic failure was ubiquitous across multiple tree taxa at drought induced mortality. All species assessed had 60% or higher loss of xylem hydraulic conductivity, consistent with proposed theoretical and modelled survival thresholds. We found diverse responses in non-structural carbohydrate reserves at mortality, indicating that evidence supporting carbon starvation was not universal. Reduced non-structural carbohydrates were more common for gymnosperms than angiosperms, associated with xylem hydraulic vulnerability, and may have a role in reducing hydraulic function. Our finding that hydraulic failure at drought-induced mortality was persistent across species indicates that substantial improvement in vegetation modelling can be achieved using thresholds in hydraulic function
A multi-species synthesis of physiological mechanisms in drought-induced tree mortality
Widespread tree mortality associated with drought 92 has been observed on all forested continents, and global change is expected to exacerbate vegetation vulnerability. Forest mortality has implications for future biosphere-atmosphere interactions of carbon, water, and energy balance, and is poorly represented in dynamic vegetation models. Reducing uncertainty requires improved mortality projections founded on robust physiological processes. However, the proposed mechanisms of drought-induced mortality, including hydraulic failure and carbon starvation, are unresolved. A growing number of empirical studies have investigated these mechanisms, but data have not been consistently analyzed across species and biomes using a standardized physiological framework. Here we show that xylem hydraulic failure was ubiquitous across multiple tree taxa at drought induced mortality. All species assessed had 60% or higher loss of xylem hydraulic conductivity, consistent with proposed theoretical and modelled survival thresholds. We found diverse responses in non-structural carbohydrate reserves at mortality, indicating that evidence supporting carbon starvation was not universal. Reduced non-structural carbohydrates were more common for gymnosperms than angiosperms, associated with xylem hydraulic vulnerability, and may have a role in reducing hydraulic function. Our finding that hydraulic failure at drought-induced mortality was persistent across species indicates that substantial improvement in vegetation modelling can be achieved using thresholds in hydraulic function
Recommended from our members
Energetic particle influence on the Earth's atmosphere
This manuscript gives an up-to-date and comprehensive overview of the effects of energetic particle precipitation (EPP) onto the whole atmosphere, from the lower thermosphere/mesosphere through the stratosphere and troposphere, to the surface. The paper summarizes the different sources and energies of particles, principally
galactic cosmic rays (GCRs), solar energetic particles (SEPs) and energetic electron precipitation (EEP). All the proposed mechanisms by which EPP can affect the atmosphere
are discussed, including chemical changes in the upper atmosphere and lower thermosphere, chemistry-dynamics feedbacks, the global electric circuit and cloud formation. The role of energetic particles in Earthâs atmosphere is a multi-disciplinary problem that requires expertise from a range of scientific backgrounds. To assist with this synergy, summary tables are provided, which are intended to evaluate the level of current knowledge of the effects of energetic particles on processes in the entire atmosphere
- âŠ