71 research outputs found
Electronic Selection Rules Controlling Dislocation Glide in bcc Metals
The validity of the structure-property relationships governing the
deformation behavior of bcc metals was brought into question with recent {\it
ab initio} density functional studies of isolated screw dislocations in Mo and
Ta. These existing relationships were semiclassical in nature, having grown
from atomistic investigations of the deformation properties of the groups V and
VI transition metals. We find that the correct form for these
structure-property relationships is fully quantum mechanical, involving the
coupling of electronic states with the strain field at the core of long
screw dislocations.Comment: 4 pages, 2 figure
A Framework for Examining Social Stress and Susceptibility to Air Pollution in Respiratory Health
Objective: There is growing interest in disentangling the health effects of spatially clustered social and physical environmental exposures and in exploring potential synergies among them, with particular attention directed to the combined effects of psychosocial stress and air pollution. Both exposures may be elevated in lower-income urban communities, and it has been hypothesized that stress, which can influence immune function and susceptibility, may potentiate the effects of air pollution in respiratory disease onset and exacerbation. In this paper, we attempt to synthesize the relevant research from social and environmental epidemiology, toxicology, immunology, and exposure assessment to provide a useful framework for environmental health researchers aiming to investigate the health effects of environmental pollution in combination with social or psychological factors. Data synthesis: We review the existing epidemiologic and toxicologic evidence on synergistic effects of stress and pollution, and then describe the physiologic effects of stress and key issues related to measuring and evaluating stress as it relates to physical environmental exposures and susceptibility. Finally, we identify some of the major methodologic challenges ahead as we work toward disentangling the health effects of clustered social and physical exposures and accurately describing the interplay among these exposures. Conclusions: There is still tremendous work to be done toward understanding the combined and potentially synergistic health effects of stress and pollution. As this research proceeds, we recommend careful attention to the relative temporalities of stress and pollution exposures, to nonlinearities in their independent and combined effects, to physiologic pathways not elucidated by epidemiologic methods, and to the relative spatial distributions of social and physical exposures at multiple geographic scales
Does traffic exhaust contribute to the development of asthma and allergic sensitization in children: findings from recent cohort studies
The aim of this review was to assess the evidence from recent prospective studies that long-term traffic pollution could contribute to the development of asthma-like symptoms and allergic sensitization in children. We have reviewed cohort studies published since 2002 and found in PubMed in Oct 2008. In all, 13 papers based on data from 9 cohorts have evaluated the relationship between traffic exposure and respiratory health. All surveys reported associations with at least some of the studied respiratory symptoms. The outcome varied, however, according to the age of the child. Nevertheless, the consistency in the results indicates that traffic exhaust contributes to the development of respiratory symptoms in healthy children. Potential effects of traffic exhaust on the development of allergic sensitization were only assessed in the four European birth cohorts. Long-term exposure to outdoor air pollutants had no association with sensitization in ten-year-old schoolchildren in Norway. In contrast, German, Dutch and Swedish preschool children had an increased risk of sensitization related to traffic exhaust despite fairly similar levels of outdoor air pollution as in Norway. Traffic-related effects on sensitization could be restricted to individuals with a specific genetic polymorphism. Assessment of gene-environment interactions on sensitization has so far only been carried out in a subgroup of the Swedish birth cohort. Further genetic association studies are required and may identify individuals vulnerable to adverse effects from traffic-related pollutants. Future studies should also evaluate effects of traffic exhaust on the development and long term outcome of different phenotypes of asthma and wheezing symptoms
Scattering of He-3 Atoms from He-4 Surfaces
We develop a first principles, microscopic theory of impurity atom scattering
from inhomogeneous quantum liquids such as adsorbed films, slabs, or clusters
of He-4. The theory is built upon a quantitative, microscopic description of
the ground state of both the host liquid as well as the impurity atom. Dynamic
effects are treated by allowing all ground-state correlation functions to be
time-dependent.
Our description includes both the elastic and inelastic coupling of impurity
motion to the excitations of the host liquid. As a specific example, we study
the scattering of He-3 atoms from adsorbed He-4 films. We examine the
dependence of ``quantum reflection'' on the substrate, and the consequences of
impurity bound states, resonances, and background excitations for scattering
properties.
A thorough analysis of the theoretical approach and the physical
circumstances point towards the essential role played by inelastic processes
which determine almost exclusively the reflection probabilities. The coupling
to impurity resonances within the film leads to a visible dependence of the
reflection coefficient on the direction of the impinging particle.Comment: 36 pages, 16 figure
Urban air pollution and emergency room admissions for respiratory symptoms: a case-crossover study in Palermo, Italy
<p>Abstract</p> <p>Background</p> <p>Air pollution from vehicular traffic has been associated with respiratory diseases. In Palermo, the largest metropolitan area in Sicily, urban air pollution is mainly addressed to traffic-related pollution because of lack of industrial settlements, and the presence of a temperate climate that contribute to the limited use of domestic heating plants. This study aimed to investigate the association between traffic-related air pollution and emergency room admissions for acute respiratory symptoms.</p> <p>Methods</p> <p>From January 2004 through December 2007, air pollutant concentrations and emergency room visits were collected for a case-crossover study conducted in Palermo, Sicily. Risk estimates of short-term exposures to particulate matter and gaseous ambient pollutants including carbon monoxide, nitrogen dioxide, and sulfur dioxide were calculated by using a conditional logistic regression analysis.</p> <p>Results</p> <p>Emergency departments provided data on 48,519 visits for respiratory symptoms. Adjusted case-crossover analyses revealed stronger effects in the warm season for the most part of the pollutants considered, with a positive association for PM<sub>10 </sub>(odds ratio = 1.039, 95% confidence interval: 1.020 - 1.059), SO<sub>2 </sub>(OR = 1.068, 95% CI: 1.014 - 1.126), nitrogen dioxide (NO<sub>2</sub>: OR = 1.043, 95% CI: 1.021 - 1.065), and CO (OR = 1.128, 95% CI: 1.074 - 1.184), especially among females (according to an increase of 10 μg/m<sup>3 </sup>in PM<sub>10</sub>, NO<sub>2</sub>, SO<sub>2</sub>, and 1 mg/m<sup>3 </sup>in CO exposure). A positive association was observed either in warm or in cold season only for PM<sub>10</sub>.</p> <p>Conclusions</p> <p>Our findings suggest that, in our setting, exposure to ambient levels of air pollution is an important determinant of emergency room (ER) visits for acute respiratory symptoms, particularly during the warm season. ER admittance may be considered a good proxy to evaluate the adverse effects of air pollution on respiratory health.</p
Geography, generalisability, and susceptibility in clinical trials
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FDI in hot labour markets: The implications of the war for talent
This paper highlights an inherent contradiction that exists within investment promotion activities in rich countries. Since the financial crisis, many inward investment agencies have shifted their activities from job creation per se to seeking to attract investment in high-tech activities. Such knowledge-intensive sectors are engaged in what has become referred to as “the war for talent”, so locations need to understand their value proposition to firms, especially where labour is tight. This paper explores the implications of this, in terms of the impact on employment and earnings of high skilled labour. We show that, because skill shortages already exist in many of these sectors, seeking to attract inward investment in these sectors simply causes the earnings of such workers to be bid up, and employment in the incumbent sector to fall. We highlight the over-riding importance that firms place on the availability of skilled labour when determining locations, and how policies which promote labour market flexibility, particularly through investment in skills to address skill shortages, can significantly mitigate the adverse effects, which tend to be more keenly felt in poorer regions of Europe where skilled labour is in even shorter supply
Reestablishing Stability and Avoiding a Credit Crunch: Comparing Different Bad Bank Schemes
Psychosocial work factors and social inequalities in psychological distress: a population-based study
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