Cross-shelf and seasonal variation in larval fish assemblages on the southeast United States continental shelf off the coast of Georgia

Seasonal and cross-shelf patterns were investigated in larval fish assemblages on the continental shelf off the coast of Georgia. The influence of environmental factors on larval distributions also was examined, and larval transport processes on the shelf were considered. Ichthyoplankton and environmental data were collected approximately every other month from spring 2000 to winter 2002. Ten stations were repeatedly sampled along a 110-km cross-shelf transect, including four stations in the vicinity of Gray’s Reef National Marine Sanctuary. Correspondence analysis (CA) on untransformed community data identified two seasonal (warm weather [spring, summer, and fall] and winter) and three cross-shelf larval assemblages (inner-, mid-, and outer-shelf ). Five environmental factors (temperature, salinity, density, depth of the water column, and stratification) were related to larval cross-shelf distribution. Specifically, increased water column stratification was associated with the outer-shelf assemblage in spring, summer, and fall. The inner shelf assemblage was associated with generally lower temperatures and lower salinities in the spring and summer and higher salinities in the winter. The three cross-shelf regions indicated by the three assemblages coincided with the location of three primary water masses on the shelf. However, taxa occurring together within an assemblage were transported to different parts of the shelf; thus, transport across the continental shelf off the coast of Georgia cannot be explained solely by twodimensional physical factors

Vapor phase growth technique and system for several 3-5 compound semiconductors Quarterly technical report

Vapor phase growth technique and system for group 3A and 5A compound semiconductor

The relationship between mental toughness and cognitive control: evidence from the item-method directed forgetting task

Previous research by the authors found that mental toughness, as measured by the Mental Toughness Questionnaire 48 (MTQ48; Clough, P.J., Earle, K., & Sewell, D. [2002]. Mental toughness: the concept and its measurement. In I. Cockerill (Ed.), Solutions in sport psychology [pp. 32–43]. London: Thomson Publishing), was significantly associated with performance on the list-method directed forgetting task. The current study extends this finding to the item-method directed forgetting task in which the instruction to Remember or Forget is given after each item in the study list. A significant positive association was found between the correct recognition of Remember words and the emotional control subscale of the MTQ48. No significant associations were observed with other measures of mental toughness or personality. The findings are discussed in terms of the relationship between mental toughness and cognitive control

Radiation Damage Studies of Silicon Photomultipliers

We report on the measurement of the radiation hardness of silicon photomultipliers (SiPMs) manufactured by Fondazione Bruno Kessler in Italy (1 mm$^2$ and 6.2 mm$^2$), Center of Perspective Technology and Apparatus in Russia (1 mm$^2$ and 4.4 mm$^2$), and Hamamatsu Corporation in Japan (1 mm$^2$). The SiPMs were irradiated using a beam of 212 MeV protons at Massachusetts General Hospital, receiving fluences of up to $3 \times 10^{10}$ protons per cm$^2$ with the SiPMs at operating voltage. Leakage currents were read continuously during the irradiation. The delivery of the protons was paused periodically to record scope traces in response to calibrated light pulses to monitor the gains, photon detection efficiencies, and dark counts of the SiPMs. The leakage current and dark noise are found to increase with fluence. Te leakage current is found to be proportional to the mean square deviation of the noise distribution, indicating the dark counts are due to increased random individual pixel activation, while SiPMs remain fully functional as photon detectors. The SiPMs are found to anneal at room temperature with a reduction in the leakage current by a factor of 2 in about 100 days.Comment: 35 pages, 25 figure

Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii

Guanylate binding proteins (GBPs) are a family of large interferon‐inducible GTPases that are transcriptionally upregulated upon infection with intracellular pathogens. Murine GBPs (mGBPs) including mGBP1 and 2 localize to and disrupt pathogen‐containing vacuoles (PVs) resulting in the cell‐autonomous clearing or innate immune detection of PV‐resident pathogens. Human GBPs (hGBPs) are known to exert antiviral host defense and activate the NLRP3 inflammasome, but it is unclear whether hGBPs can directly recognize and control intravacuolar pathogens. Here, we report that endogenous or ectopically expressed hGBP1 fails to associate with PVs formed in human cells by the bacterial pathogens Chlamydia trachomatis or Salmonella typhimurium or the protozoan pathogen Toxoplasma gondii. While we find that hGBP1 expression has no discernible effect on intracellular replication of C. trachomatis and S. typhimurium, we observed enhanced early Toxoplasma replication in CRISPR hGBP1‐deleted human epithelial cells. We thus identified a novel role for hGBP1 in cell‐autonomous immunity that is independent of PV translocation, as observed for mGBPs. This study highlights fundamental differences between human and murine GBPs and underlines the need to study the functions of GBPs at cellular locations away from PVs

Vapor phase growth technique and system for several III-V compound semiconductors Interim scientific report

Vapor phase growth method for single crystalline preparation of gallium nitride, gallium arsenide alloy, and gallium antimonide allo

Making the case for green infrastructure : lessons from best practice

This report aims to provide built environment professionals with case study insights into the nature of GI decision making. Insights are shared from the project teams and stakeholders involved. These cover the GI benefits attained, the decision making process followed and the barriers, solutions and lessons learned. This report explores five Green Infrastructure (GI) case studies; Marks & Spencer Newcastle, Wild West End, Victory Oak, Kingsbrook and City of Trees. This report was prepared with funding from the Natural Environment Research Council (NERC) by the UK Green Building Council (UKGBC) with the University of Manchester and the University of Sheffield as part of project NE/N01748/1. The report compliments other outputs produced as part of the project. These include: • Practical how-to guide: Developing and implementing a green infrastructure strategy • Understanding Green Infrastructure at Different Scales The reports also features a ‘Green Infrastructure Best Practice: Route Map’. This provides a synthesis of the current GI best practice which applies to different decision making stages in the development life cycle. This was created based on interview centred research conducted for the Green Growth Project and follows the key steps set out in the Practical How-to-Guide