27 research outputs found
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis Martin
- Dennis Martin S
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
- Dickinson Christina
- Dickson Christine
- Dima Sofia
- Dinsmore Lynn
- Dixon Lynn
- Dobson Tracey
- Dodd Angela
- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johann C
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
- Hazel Beth
- Hedstrom Amanda
- Hedstrom Amanda
- Hemsley Anthony
- Henry Margo
- Herman Jane
- Hervey Simon
- Hewitt Jonathan
- Hiden Joanne
- Hogan Caroline
- Hogg Valerie
- Holden Melinda
- Holmes Clare
- Homan Jane
- Hooley Michaela
- Horan Kathleen
- Horton Sarah
- Hostettler Isabel
- Hove Dionne
- Howaniec Laura
- Howard Gabriella
- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
- Humphreys Louise
- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shazad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
- Jones Kirsty
- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
- Keegan Breffni
- Keeling Elizabeth
- Keenan Samantha
- Kelavkar Shyam
- Kelly Christine
- Kelly Debs
- Kelly Jim
- Kelly Siobhan
- Keltos Marketa
- Kennedy James
- Kennedy Kate
- Kenton Antony
- Kerin Lourda
- Kerr Enda
- Kerr Gillian
- Keshvara Rekha
- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- Macleod Malcolm
- MacLeod Mary
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Minks David P.
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
- Muddegowda Girish
- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray Gordon D
- Musarrat Kashif
- Myint Min
- Naeem Muhammad
- Naing Zin
- Nair Anand
- Nallasivan Arumugam
- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby David E
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
- Nisar Nabeela
- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- OConnell Janice
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
- Peters Jenny
- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
- Ponnambath Suheil
- Poultney Una
- Pound Susan
- Power Michael
- Pressly Vanessa
- Price Fiona
- Proeschel Harald
- Punekar Shuja
- Punter Martin
- Pusalkar Aparna
- Putterill Janet
- Quinn Leanne
- Quinn Outi
- Qureshi Sammie
- Ragab Suzanne
- Raghunathan Senthil
- Rahman Bithi
- Rai Baljinder
- Raj Sonia
- Rajapakse Anoja
- Rajkumar Chakravarthi
- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodrigues Mark A
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock Peter A G
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg Nikola
- Sprigg Nikola
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen Jacqueline
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow Cathie
- Sudlow Cathie L M
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw Joanna M
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring David
- Werring David J
- Whitcher Alison
- White James
- White Julie
- White Philip M
- White Susan
- Whiteley William
- Whiteley William N
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 22/05/2019
- Field of study
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan Kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis MS
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
- Dickinson Christina
- Dickson Christine
- Dima Sofia
- Dinsmore Lynn
- Dixon Lynn
- Dobson Tracey
- Dodd Angela
- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
- Hazel Beth
- Hedstrom Amanda
- Hedstrom Amanda
- Hemsley Anthony
- Henry Margo
- Herman Jane
- Hervey Simon
- Hewitt Jonathan
- Hiden Joanne
- Hogan Caroline
- Hogg Valerie
- Holden Melinda
- Holmes Clare
- Homan Jane
- Hooley Michaela
- Horan Kathleen
- Horton Sarah
- Hostettler Isabel
- Hove Dionne
- Howaniec Laura
- Howard Gabriella
- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
- Humphreys Louise
- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shahzad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
- Jones Kirsty
- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
- Keegan Breffni
- Keeling Elizabeth
- Keenan Samantha
- Kelavkar Shyam
- Kelly Christine
- Kelly Debs
- Kelly Jim
- Kelly Siobhan
- Keltos Marketa
- Kennedy James
- Kennedy Kate
- Kenton Antony
- Kerin Lourda
- Kerr Enda
- Kerr Gillian
- Keshvara Rekha
- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- MacLeod Mary
- Macleod MR
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
- Muddegowda Girish
- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray GD
- Musarrat Kashif
- Myint Min
- Naeem Muhammad
- Naing Zin
- Nair Anand
- Nallasivan Arumugam
- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby DE
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
- Nisar Nabeela
- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Janice
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
- Peters Jenny
- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
- Ponnambath Suheil
- Poultney Una
- Pound Susan
- Power Michael
- Pressly Vanessa
- Price Fiona
- Proeschel Harald
- Punekar Shuja
- Punter Martin
- Pusalkar Aparna
- Putterill Janet
- Quinn Leanne
- Quinn Outi
- Qureshi Sammie
- Ragab Suzanne
- Raghunathan Senthil
- Rahman Bithi
- Rai Baljinder
- Raj Sonia
- Rajapakse Anoja
- Rajkumar Chakravarthi
- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock PAG
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg N
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen J
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow CLM
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan Kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis MS
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
- Dickinson Christina
- Dickson Christine
- Dima Sofia
- Dinsmore Lynn
- Dixon Lynn
- Dobson Tracey
- Dodd Angela
- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
- Hazel Beth
- Hedstrom Amanda
- Hedstrom Amanda
- Hemsley Anthony
- Henry Margo
- Herman Jane
- Hervey Simon
- Hewitt Jonathan
- Hiden Joanne
- Hogan Caroline
- Hogg Valerie
- Holden Melinda
- Holmes Clare
- Homan Jane
- Hooley Michaela
- Horan Kathleen
- Horton Sarah
- Hostettler Isabel
- Hove Dionne
- Howaniec Laura
- Howard Gabriella
- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
- Humphreys Louise
- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shahzad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
- Jones Kirsty
- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
- Keegan Breffni
- Keeling Elizabeth
- Keenan Samantha
- Kelavkar Shyam
- Kelly Christine
- Kelly Debs
- Kelly Jim
- Kelly Siobhan
- Keltos Marketa
- Kennedy James
- Kennedy Kate
- Kenton Antony
- Kerin Lourda
- Kerr Enda
- Kerr Gillian
- Keshvara Rekha
- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- MacLeod Mary
- Macleod MR
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
- Muddegowda Girish
- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray GD
- Musarrat Kashif
- Myint Min
- Naeem Muhammad
- Naing Zin
- Nair Anand
- Nallasivan Arumugam
- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby DE
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
- Nisar Nabeela
- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Janice
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
- Peters Jenny
- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
- Ponnambath Suheil
- Poultney Una
- Pound Susan
- Power Michael
- Pressly Vanessa
- Price Fiona
- Proeschel Harald
- Punekar Shuja
- Punter Martin
- Pusalkar Aparna
- Putterill Janet
- Quinn Leanne
- Quinn Outi
- Qureshi Sammie
- Ragab Suzanne
- Raghunathan Senthil
- Rahman Bithi
- Rai Baljinder
- Raj Sonia
- Rajapakse Anoja
- Rajkumar Chakravarthi
- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock PAG
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg N
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen J
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow CLM
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study
- Author
- Abbas Abeera
- Abbas Imran
- Abbott Nick
- Abdalla El-Rasheed
- Absar Mohammed
- Achuthan Raj
- Adwani Asha
- Agabiti Ennio
- Agrawal Amit
- Ainsworth Rachel
- Aitken Jane
- Akolekar Deepika
- Al-Ishaq Zaid
- Al-Mufti Ragheed
- AL-Zawi Abdalla Saad Abdalla
- Alder Louise
- Alkistawi Firas Eddin Bachir
- Allen Michael J.
- Allum William H.
- Amin Khalid
- Ansari Aonghus
- Asgeirsson Kristjan
- Athanasiou Irene
- Athwal Ruvinder
- Azmy Iman
- Bakri Nur Amalina Che
- Banerjee Dibyesh
- Banks Jenny
- Barkeji Musa
- Barker Sarah
- Barnes Nicola
- Barry Peter A.
- Barua Ellora
- Bathla Sonia
- Batt Jeremy
- Benson John
- Bentley James
- Betal Dibendu
- Betambeau Nadine
- Bezzaa Sabrina
- Bichoo Raouef Ahmed
- Bonomi Riccardo
- Bosch Karen
- Boundouki George
- Bramley Maria
- Brown Iain
- Bunza Ralia
- Burrah Rajaram
- Byrne Gerard
- Cain Henry
- Callaghan Maria
- Camacho Elizabeth M.
- Cariati Massimiliano
- Carmichael Amtul
- Cartlidge Christopher W. J.
- Chagla Leena
- Chalmers Ritchie
- Chambers Alice
- Chandrasekharan Sankaran
- Chandrashekar Mysore
- Charalampoudis Petros
- Chatterjee Sumohan
- Chaudhry Anushka
- Cheung Kwok-Leung
- Chong Kelvin
- Chopra Sharat
- Chouhan Ashok
- Chrysafi Ada
- Clayton Elizabeth
- Clayton Gillian
- Coles Charlotte E.
- Cook James
- Cook Lorna
- Coombs Nathan
- Copson Ellen
- Courtney Alona
- Courtney Carol-Ann
- Cox Karina
- Critchley Adam
- Cuffolo Giulio
- Cutress Ramsey I.
- Daltrey Ian
- Dani Mohsin
- Dash Isabella
- Dave Rajiv V.
- Davies Eleri
- de Silva Tania S.
- Dent Helen
- Devalia Haresh
- Dimopoulos Nikitas
- Dodwell David
- Douek Michael
- Doughty Julie
- Drew Philip
- Dua Sascha
- Dumitru Dorin
- Dunn Julie
- Egbeare Donna
- Eid Raja
- Elahi M. Bilal
- Elamass Mohamed
- Elfadl Dalia
- Elkorety Mohamed
- Elsberger Beatrix
- English Rachel Elizabeth
- Exarchos Georgios
- Fafemi Oladapo
- Fairbrother Patricia
- Fairhurst Katherine
- Fatayer Hiba
- Ferguson Douglas
- Forouhi Parto
- Franks Joanna
- Fuller Mairi
- Gahir Jasdeep
- Gallegos Nicholas
- Gandamihardja Tasha
- Gandhi Ashu
- Garreffa Emanuele
- Gathani Toral
- Gill Jasper
- Girgis Mina
- Goh Ngee-Ming
- Gopalan Vallipuran
- Govindarajulu Sasi
- Gowda Manoj
- Goyal Amit
- Goyal Sumit
- Gui Gerald
- Gvaramadze Anzors
- Hadjiminas Demetrios
- Hague Matthew
- Hamad Ahmed
- Hamed Hisham
- Harborough Kathryn E.
- Harding-Mackean Claudia
- Hardy Rob
- Hargreaves Anita
- Harries Simon
- Harvey James
- Hawkins Simon
- Heeney Anna
- Henderson Julia
- Highton Lyndsey
- Hill Arnold D. K.
- Hogan Brian
- Hogben Katy
- Holcombe Chris
- Hollywood Ciaran
- Horgan Kieran
- Horne Sarah
- Horsnell Jonathan D.
- Hurley Anna R.
- Hussien Maged
- Imran Abbas
- Irvine Tracey
- Irwin Gareth W.
- Isgar Brian
- Ives Charlotte
- Jacklin Rosamond
- Jafferbhoy Sadaf
- Jain Urvashi
- James Karen
- James Ruth
- Jenkins Stephanie C.
- Jibril Jibril
- Johnson Richard
- Jones Lucie
- Joshi Sanjay
- Kalakouti Eliana
- Kallaway Charlotte
- Kalra Loraine
- Kantola Venla
- Karagiannidis Georgios
- Kattakayam Arjun
- Kaushik Monika
- Kenny Frances
- Khalifa Eiman
- Khan Lucy R.
- Khout Hazem
- Kiernan Tamara
- Kim Baek
- King Polly
- Kirkham Jamie J.
- Kirkpatrick Katharine
- Kirwan Cliona C.
- Knight Alex
- Knowles Hannah
- Kothari Ashutosh
- Krupa Jaroslaw
- Krupa Katherine
- Krzyzanowska Catherine
- Laban Christiana
- Lafi Mohamed
- Lai Lee-Min
- Lambert Kelly
- Laurence Nicola
- Law Rebekah
- Lee Rachel Xue Ning
- Leff Daniel R.
- Liptay-Wagner Peter
- Lobo Cheryl
- Lund Jonathan
- Maalo Joseph
- Macinnes Emma
- MacLean Gael
- Macmillan Robert
- Mallidis Evangelos
- Mallon Peter
- Marla Sekhar
- Marsh Simon
- Martin Lee
- Masannat Yazan
- Massey Julia
- Matey Pilar
- Mathen Vinod
- Mathers Helen
- Mazari Fayyaz
- McCulley Stephen
- McEvoy Kat
- McGoldrick Ciara
- McIntosh Jamie
- McIntosh Stuart A.
- Mckenzie Shireen
- McManus Penelope
- Mehta Disha
- Merker Louise
- Mikhael Youhana
- Mirshekar-Syahkal Bahar
- Mitchell Geraldine
- Mondani Giuseppina
- Monib Sherif
- Moody Alice
- Mortimer Caroline
- Mullan Michelle
- Mullen Russell
- Murphy John
- Mylvaganam Senthurun
- Nair Rajive
- Najeeb Erum
- Narayanan Sankaran
- Nasir Nabila
- Navin Channegowda
- Noor Lubna
- Noronha Jarin Louis
- Ntakomyti Eleni
- Odofin Olubunmi
- Olsen Sisse
- Oni Georgette
- Ooi Jane
- O’Connell Rachel
- Pain Simon
- Pakzad Farrokh
- Parmeshwar Rishikesh
- Partlett Polly
- Patani Neill
- Peck Jennifer
- Peerlink Inga
- Pereira Bernadette
- Phyu Saung Hnin
- Pieri Andrew
- Pilgrm Simon
- Podesta Carl
- Pogson Caroline
- Poonawala Shabbir
- Potter Shelley
- Potter Shelley
- Power Colm
- Prusty Lydia
- Quinn Edel
- Ralph Jane
- Ramzi Sa’ed
- Rana Dheer Singh
- Rapisarda Fabio
- Rasheed Tuabin
- Rathinaezhil Rathi
- Rattay Tim
- Ravichandran Duraisamy
- Ray Atanu
- Rayter Zenon
- Remoundos Dennis
- Rew David
- Robb Henry Douglas
- Robertson Stuart
- Roche Nicola
- Romics Laszlo
- Rowland Matthew
- Roy Pankaj
- Rusby Jennifer E.
- Rutherford Claire Louise
- Saha Sunita
- Sahu Ajay
- Sait Mohamed Razick
- Sakellariou Vasileios
- Salem Fathi
- Salih Ali
- Salman Muhammad
- Salman Reem
- Salvador Reginald
- Sami Amtul
- Sarakbi Wail Al
- Sardar Mini V.
- Sarker Masuma
- Sasi Walid
- Satpathy Anjana
- Scally Norah
- Segaran Ashvina
- Sein Tin Aung
- Seward Joanna
- Shaheed Samy
- Sharif Mohammad Amir
- Sharma Anita
- Sharma Anup
- Sharma Nisha
- Shere Mike
- Shin Hyunjin
- Shokuhi Sheila
- Shrotri Anu
- Sibbering David Mark
- Simonca Claudiu
- Sircar Tapan
- Sloan Samantha A.
- Smith Simon
- Smyth Elizabeth
- Somasundaram Santosh
- Sotheran Wendy
- Soulsby Rachel
- Soumian Soni
- Sousa Emma de
- St John Edward R. C.
- Stallard Sheila
- Stanilov Noyko
- Suleiman Usama
- Sulieman Mona
- Sutton Richard
- Sweetland Helen M.
- Tabbakh Rami
- Tanhueco Angeline
- Tansley Anne
- Taraki Zarghuna
- Taxiarchi Vicky P.
- Taylor Amanda
- Thekkinkattil Dinesh
- Thiruchelvam Paul
- Thomas Robert
- Thomson Simon
- Thorne Amanda
- Tillett Rachel
- Touqan Nader
- Tuffaha Hussein
- Turner Jane
- Turton Philip
- Urquhart Gordon
- Valassiadou Kalliope
- Vashisht Rajiv
- Vatish Jamie
- Verroiotou Maria
- Vidya Raghavan
- Vinayagam Raman
- Wahedna Yasmin
- Waheed Shamaela
- Wallace Sharon
- Walsh Adam
- Wardle Stacy
- Whisker Lisa
- Whitehead Ian
- Wignarajah Primeera
- Williams Chloe
- Williams Kate E.
- Williams Samantha K.
- Williams-Jones Susan
- Wilson Christopher
- Young Ian
- Youssef Mina M. G.
- Zammit Charles
- Zechmeister Katalin
- Zeidan Bashar
- Publication venue
- British Journal of Cancer
- Publication date
- 10/12/2020
- Field of study
Abstract: Background: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. Methods: This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated ‘standard’ or ‘COVID-altered’, in the preoperative, operative and post-operative setting. Findings: Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had ‘COVID-altered’ management. ‘Bridging’ endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidance, immediate breast reconstruction was avoided (n = 299). Where adjuvant chemotherapy was omitted (n = 81), the median benefit was only 3% (IQR 2–9%) using ‘NHS Predict’. There was the rapid adoption of new evidence-based hypofractionated radiotherapy (n = 781, from 46 units). Only 14 patients (1%) tested positive for SARS-CoV-2 during their treatment journey. Conclusions: The majority of ‘COVID-altered’ management decisions were largely in line with pre-COVID evidence-based guidelines, implying that breast cancer survival outcomes are unlikely to be negatively impacted by the pandemic. However, in this study, the potential impact of delays to BC presentation or diagnosis remains unknown
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Aberami Chandrakumar
- Abhijit Mate
- Adam Hague
- Adam Webber
- Adrian Barry
- Adrian Bergin
- Adrian Blight
- Adrian Butler
- Adrian Parry-Jones
- Afaq Saulat
- Afaq Saulat
- Afnan Chaudhry
- Afraim Salek-Haddadi
- Aguilar
- Ahamad Hassan
- Ahmad Maatouk
- Ahmed Osman
- Aidan Hutchison
- Aileen McGrath
- Ailsa Fulton
- Aine Wallace
- Ajay Bhalla
- Ajmal Anversha
- Al-Shahi Salman
- Al-Shahi Salman
- Al-Shahi Salman
- Alda Remegoso
- Alex Blades
- Alex Ramshaw
- Alex Shah
- Alexandra Pitt-Ford
- Alfonso Tanate
- Ali Ali
- Ali James
- Alicia Rodgers
- Alison McLoughlin
- Alison Whitcher
- Alison Wiltshire
- Allan MacRaild
- Allan Walker
- Alpha Anthony
- Amanda Buck
- Amanda Hedstrom
- Amanda Hedstrom
- Amanda Smart
- Amber Siddiqui
- Amit Mistri
- Amy Ashton
- Amy Steele
- Anand Nair
- Andrea Hall
- Andrea Ingham
- Andrew Moores
- Andrew Sigsworth
- Andrew Smith
- Andrew Stanners
- Andrew Stone
- Andrew Young
- Anette David
- Angela Bell
- Angela Bowring
- Angela Chamberlain
- Angela Cook
- Angela Dodd
- Angela Stevens
- Angela Welch
- Angela Willberry
- Anita Goff
- Anja Ljubez
- Ann Deary
- Ann Needle
- Anna Verrion
- Anne Hardwick
- Anne Hayes
- Anne Nicolson
- Anne Oshodi
- Anne Suttling
- Annemarie Hunter
- Anoja Rajapakse
- Anthea Parry
- Anthony Byrne
- Anthony Hemsley
- Antony Kenton
- Anu Joyson
- Anwer Siddiqui
- Aparna Pusalkar
- Aravind Manoj
- Arindam Kar
- Arshad Majis
- Arshi Iqbal
- Arumugam Nallasivan
- Arun Singh
- Arunkumar Annamalai
- Aryelly Rodriguez
- Ashish Macaden
- Ashleigh Walters
- Ashraf Ahmed
- Ashraf Nasim
- Audrey Thomson
- Avani Shukla
- Azlisham Mohd Nor
- Azra Banaras
- Baigent
- Balakrishna Kumar
- Baljinder Rai
- Baljit Jagpal
- Bander Dallol
- Barbara Longland
- Barbara Madigan
- Barbara Williams-Yesson
- Barry Moynihan
- Basaam Aweid
- Becky Jupp
- Bejot
- Belinda Wroath
- Bella Richard
- Benjamin Hunt
- Benjamin Hyams
- Benjamin Jackson
- Benjamin Jelley
- Benjamin Tomlinson
- Bernard Esisi
- Bernard Esisi
- Beth Hazel
- Bethan Charles
- Bethan Morse
- Betty Mokoena
- Bev Maund
- Beverley McClelland
- Beverly MacLennan
- Bharath Kumar Cheripelli
- Bhavini Patel
- Biffi
- Biju Bhaskaran
- Bindu Gregory
- Bithi Rahman
- Breffni Keegan
- Brian Clarke
- Brian MacInnes
- Brigid Hairsine
- Brigitte Yip
- Bruno
- Carinna Vickers
- Carla Jordan
- Carmen Constantin
- Carol Denniss
- Carol Graham
- Carol Jeffs
- Carol Williams
- Carole Green
- Carole Hays
- Caroline Bagnall
- Caroline Blair
- Caroline Blair
- Caroline Clarke
- Caroline Clay
- Caroline Crosbie
- Caroline Davies
- Caroline Hogan
- Caroline Lambert
- Caroline Lovelock
- Caroline McGhee
- Caroline Roughan
- Caroline Watchurst
- Cassilda Peixoto
- Catherine Ovington
- Catherine Plewa
- Cathy Mason
- Catrin Blank
- Chakravarthi Rajkumar
- Champa Patel
- Chantel Cox
- Charde Naylor
- Charlotte Barr
- Charlotte Culmsee
- Charlotte Eglinton
- Charlotte Eglinton
- Charlotte Fox
- Charlotte Perkins
- Chelsea Causley
- Cherish Boxall
- Chloe Cox
- Chloe Hughes
- Chloe van Someren
- Chong
- Chris Patterson
- Christian Hansen
- Christina Dickinson
- Christine Dickson
- Christine Kamara
- Christine Kelly
- Christine Lerpiniere
- Christine Lerpiniere
- Christine McAlpine
- Christine Roffe
- Christine Schofield
- Christopher Allen
- Christopher Matthews
- Chukwuka Orefo
- Claire Brown
- Claire Copeland
- Claire Cullen
- Claire Hughes
- Claire James
- Claire Nott
- Claire Nott
- Claire Stephens
- Claire Sutton
- Claire Triscott
- Claire Triscott
- Clare Buckley
- Clare Doyle
- Clare Holmes
- Clark
- CLM Sudlow
- Colin Baigent
- Colin Jenkins
- Connor McGill
- Corinne Pawley
- Counsell
- Damian McArdle
- Daniel Epstein
- Daniel Lasserson
- Daniela Shackcloth
- Danielle Gilmour
- David Broughton
- David Bruce
- David Buchanan
- David Cohen
- David Eveson
- David Jarrett
- David Mangion
- David Minks
- David Ngo
- David Perry
- David Strain
- David Wilson
- Dawn Tomlin
- DE Newby
- Dean Waugh
- Debbie Morgan
- Deborah Howcroft
- Deborah Walstow
- Deborah Walter
- Deborah Ward
- Debs Kelly
- Deepa Jose
- Denise Button
- Denise Donaldson
- Denise Mead
- Dennis
- Derek Esson
- Derek Esson
- Devesh Sinha
- Dheeraj Kalladka
- Diane Gulliver
- Diane Havard
- Diane Wood
- Dinesh Chadha
- Dinesh Tryambake
- Ding
- Dionne Hove
- Dipankar Dutta
- Dipayan Mitra
- Divya Tiwari
- DJ Werring
- Dominic Handley
- Don Sims
- Donna Butler
- Donna Doyle
- Duke Phiri
- Duncan Bailey
- Duncan Wilson
- Ed Gamble
- Edith Wood
- Edward Littleton
- Elaine Amis
- Eleni Sakka
- Elio Giallombardo
- Eliza Foster
- Elizabeth Barrie
- Elizabeth Keeling
- Ellen Brown
- Ellie Gilham
- Elodie Murali
- Eluzai Hakim
- Emelda Veraque
- Emily Beaves
- Emily Dodd
- Emily Osborne
- Emily Rogers
- Emma Barbon
- Emma Battersby-Wood
- Emma Clarkson
- Emma Elliott
- Emma Jinks
- Emma Richards
- Emma Tallantyre
- Emmanuelle Owoyele
- Enda Kerr
- Enoch Orugun
- Eoin O'Brien
- Esther Erumere
- Eva Beranova
- Evangelos Vasileiadis
- Evelyne Burssens
- Faith Kibutu
- Farrukh Baig
- Farzana Patel
- Faye Shelton
- Fenglin Guo
- Ferghal McVerry
- Fergus Doubal
- Fiona Brodie
- Fiona Davis
- Fiona Humphries
- Fiona Moreton
- Fiona Price
- Fiona Smith
- Fiona Wright
- Flynn
- Fran Watson
- Frances Harrington
- Frances Hurford
- Frances Justin
- Francis Alipio
- Frank Sullivan
- Gabriel Rinkel
- Gabriella Howard
- Gail Hann
- Garcia-Yebenes
- Garth Ravenhill
- Gary Ford
- Gavin Bateman
- GD Murray
- Gemma Grimwood
- Gemma Marie Smith
- George Bunea
- George Ghaly
- George Harston
- George Zachariah
- Georgina Ayres
- Geraldine Landers
- Gill Rogers
- Gillian Cluckie
- Gillian Courtauld
- Gillian Kerr
- Gillian Mead
- Girish Muddegowda
- Giulia Lenti
- Glyn Fletcher
- Glyn Gainard
- Gokhale
- Gonzalez-Perez
- Gordon Blair
- Gordon Lowe
- Grace Auld
- Graeme Sangster
- Gwendoline Wilkes
- Hannah Beadle
- Hannah Crowther
- Hannah Rudenko
- Harald Proeschel
- Harbens Bhakri
- Hardi Hassan
- Hart
- Hawraman Ramadan
- Hayley Bridger
- Hayley Denic
- Hayley Kingwell
- Heather Gow
- Hedley Emsley
- Heidi Lawson
- Helen Bearne
- Helen Brew
- Helen Cochrane
- Helen Durman
- Helen Guy
- Helen Hayhoe
- Helen Moroney
- Helen Skinner
- Helen Thompson-Jones
- Hemphill
- Henry De Berker
- Hicks
- Hlaing Ni
- Hlaing Thant
- Holly Maguire
- Hróbjartsson
- Ian Reckless
- Ian Shread
- Ifan Jones
- Ifan Jones
- Ijaz Anwar
- Ilse Burger
- Iman Ahmed
- Imogen Gartrell
- Indra Chadbourn
- Indranil Mukherjee
- Inez Wynter
- Ingrid Kane
- Irene Martin
- Isabel Hostettler
- Isabel Huggett
- Isam Salih
- Isobel Amey
- Isobel Thomas
- Ivan Wiggam
- J Stephen
- Jack Perry
- Jack Roffe
- Jacqueline Furnace
- Jacqueline McKee
- Jacqui Leggett
- James Barker
- James Choulerton
- James Cunningham
- James Kennedy
- James McIlmoyle
- James Richard Marigold
- James White
- Jamie Walford
- Janak Saada
- Jane Armitage
- Jane Gaylard
- Jane Gray
- Jane Herman
- Jane Homan
- Jane Perez
- Jane Sword
- Jane Tandy
- Janet Putterill
- Janice Irvine
- Janice O'Connell
- Jason Appleton
- Javed Imam
- Javier Rojas
- Jayne Foot
- Jayne Spencer
- Jean Buxton
- Jeanette Grocott
- Jeb Palmer
- Jennifer Adil-Smith
- Jennifer Elliot
- Jennifer Hurley
- Jennifer Mitchell
- Jennifer Turfrey
- Jenny Jagger
- Jenny Peters
- Jenny Wilson
- Jessica Redgrave
- Jessica Whiteman
- Jessica Whiteman
- Jill Gallagher
- Jill Greig
- Jim Kelly
- JM Wardlaw
- Jo Bell
- Jo Fletcher
- Jo Howe
- Joanna Allison
- Joanna Breeds
- Joanna O'Reilly
- Joanne Avis
- Joanne Board
- Joanne Garfield-Smith
- Joanne Hiden
- Joanne Howard
- Joanne Mcgee
- Jobbin Francis
- Johanna Carrie
- Johannes du Plessis
- John Baker
- John Bamford
- Jon Glass
- Jonathan Birns
- Jonathan Drever
- Jonathan Emberson
- Jonathan Hewitt
- Jordan Ewing
- Jordi Morell
- Joseph Devine
- Joseph Vassallo
- Josette Milligan
- Josh Roberts
- Josin Jose
- Judith Clarke
- Judith Dube
- Juliana Sesay
- Julie Ball
- Julie Cageao
- Julie Cronin
- Julie Meir
- Julie Reddan
- Julie Reddan
- Julie White
- Justin Penge
- Kailash Krishnan
- Kamy Thavanesan
- Karen Crabtree
- Karen Dunne
- Karen Innes
- Kari Saastamoinen
- Karin Gupwell
- Karla Jennings-Preece
- Kashif Musarrat
- Kate Kennedy
- Kath Chapman
- Kath Pasco
- Katherine Marks
- Katherine Whittamore
- Kathleen Horan
- Kathryn Birchall
- Kathy Stocks
- Katja Adie
- Katrina Klaasen
- Katrina McCormick
- Katrina McCormick
- Katy Dakin
- Kausic Chatterjee
- Kay Finney
- Kayleigh Collins
- Keir
- Keith Muir
- Kelechi Njoku
- Kelly Amor
- Kelly Chan
- Kelly Marie Shaw
- Kelly Thomas
- Kelly Waterfield
- Kelly Waterfield
- Kelvin Stewart
- Ken Fotherby
- Keniesha Miller
- Kerry Pettitt
- Kerstin Knops
- Kevin Dynan
- Kevin Thorpe
- Khaled Elfandi
- Khalid Azhar
- Khalid Rashed
- Khalil Ullah
- Kheng Xiong Ng
- Kim
- Kiranjit Bharaj
- Kirsten Harvey
- Kirsty Bond
- Kirsty Harkness
- Kirsty Jones
- Kneale Metcalf
- Krishna Patel
- Lakshmanan Sekaran
- Larissa Cuenoud
- Latheef Kalathil
- Laura Burgess
- Laura Codd
- Laura Gleave
- Laura Howaniec
- Laura Latter
- Laura Tucker
- Leanne Foote
- Leanne Quinn
- Li
- Lillian Choy
- Lily Mercer
- Linda Balian
- Linda Cowie
- Linda Dunn
- Linda Jackson
- Linda Lucas
- Linda MacLiver
- Lindsey Dow
- Linetty Makawa
- Lisa Clayton-Evans
- Lisa Hyatt
- Lisa Manning
- Lisa Wilson
- Lisa Wood
- Louise Gallagher
- Louise Harrison
- Louise Humphreys
- Louise Shaw
- Lourda Kerin
- Luci Crook
- Lucia Argandona
- Lucy Belle Guthrie
- Lucy Brotherton
- Lucy Coward
- Lucy Sykes
- Luke Barron
- Lukuman Gbadamoshi
- Lynda Connor
- Lynn Dinsmore
- Lynn Dixon
- Lynne Dacey
- Léjeune Gardener
- Magdalini Krommyda
- Mahesh Dhakal
- Mahmud Sajid
- Mairead Osborn
- Malik Hussain
- Man Yee Lam
- Mandy Couser
- Mandy Doherty
- Mandy Doherty
- Mandy Edwards
- Maneesh Bhargava
- Manju Krishnan
- Manohar Kini
- Maqsud Salehin
- Marc Randall
- Margaret Ball
- Margaret Tate
- Margi Godfrey
- Margo Henry
- Maria Bokhari
- Maria Brezitski
- Marie Weinling
- Marion Walker
- Marius Venter
- Mark Barber
- Mark Garside
- Mark McCarron
- Mark Wilkinson
- Mark Willmot
- Marketa Keltos
- Martin Cooper
- Martin James
- Martin Punter
- Mary Johnes
- Mary Kambafwile
- Mary MacLeod
- Matthew Robinson
- Maxwell
- Maxwell
- Meena Chauhan
- Meena Srinivasan
- Mehran
- Mehran Maanoosi
- Melanie Harrison
- Melinda Holden
- Mellor Zoe
- Michael Carpenter
- Michael Power
- Michaela Hooley
- Michele Tribbeck
- Michelle Bates
- Michelle Davis
- Michelle Fawcett
- Michelle Tayler
- Min Myint
- Miriam Harvey
- Mirriam Sangombe
- Mishell Cunningham
- Mmua Ngwako
- Mo Albazzaz
- Mohammad Haque
- Mohammad Irfan Alam
- Mohammad Khan
- Mohammad Nasar
- Mohammad Shahzad Iqbal
- Mohammed Moqsith
- Mohana Maddula
- Moore Sally
- MR Macleod
- MS Dennis
- Mudhar Abbdul-saheb
- Muhammad Naeem
- Muhammad Siddiq
- Murdina Bell
- Mushiya Mpelembue
- Mushtaq Wani
- N Sprigg
- Nabeela Nisar
- Naomi Jeyaraj
- Naomi Robinson
- Nasar Ahmad
- Natalie Atkinson
- Natalie Temple
- Natasha Clarke
- Natasha Schumacher
- Naval Shinh
- Naveen Gadapa
- Naweed Sattar
- Neetish Goorah
- Neha Chopra
- Neil Hunter
- Nenette Abano
- Niamh Hannon
- Niaz Mohammed
- Nic Weir
- Nichola Crouch
- Nichola Motherwell
- Nicholas Hunt
- Nicola Butterworth-Cowin
- Nicola Chapman
- Nicola Day
- Nicola Devitt
- Nicola Gainsborough
- Nicola Gilzeane
- Nicola Persad
- Nigel Smyth
- Nikhil Majmudar
- Nikhil Sharma
- Nikki Gautam
- Nilofer Dayal
- Nina Francia
- Nisha Menon
- Nnebuife Oji
- Olesia Balitska
- Olga Balazikova
- Oliver Matias
- Olivia Geraghty
- Omid Halse
- Outi Quinn
- Owen David
- Ozlem Redjep
- PAG Sandercock
- Pam Crawford
- Pasquini
- Pat Taylor
- Patrick Sutton
- Paul Findlay
- Paul Fitzsimmons
- Paul Guyler
- Paul Mudd
- Paul Nicholas
- Paula Lopez
- Paula Owings
- Pauli Walker
- Pauline Baker
- Pauline Bayliss
- Pauline Brown
- Pauline Fitzell
- Pauline Weir
- Penelope Cox
- Perry
- Peter Howard
- Peter Langhorne
- Peter Murphy
- Peter Owusu-Agyei
- Peter Slade
- Peter Wilding
- Philip Mathieson
- Philip Poku
- Philip Thomas
- Philip Thompson
- Phillip Ferdinand
- PM White
- Poon
- Prabal Datta
- Pradeep Kumar
- Prasad Siddegowda
- Pratap Rana
- Priya Bhatnagar
- Procter Sarah
- Procter Sarah
- Puneet Dangri
- Puneet Kakar
- Rachael Jones
- Rachel Crown
- Rachel Evans
- Rachel Gallifent
- Rachel Gascoyne
- Rachel Glover
- Rachel Hayman
- Rachel Teal
- Racquel Carpio
- Radim Licenik
- Raj Shekhar
- Rajalakshmi Orath Prabakaran
- Rajaram Bathula
- Rajendra Yadava
- Ralf Lindert
- Ramesh Durairaj
- Ramesh Krishnamurthy
- Rangah Niranchanan
- Ranjan Sanyal
- Ratneshwari Jha
- Rayessa Rayessa
- Razik Fathima
- Rebecca Butler
- Rebecca Clarke
- Rebecca Grue
- Rebecca Wallace
- Rebecca Wallace
- Rebecca Williams
- Rebekah Perfitt
- Rehana Bakawala
- Rekha Keshvara
- Renuka Erande
- Resti Varquez
- Richard Davey
- Richard Dewar
- Richard Donnelly
- Richard Greenwood
- Richard Miller
- Richard O'Brien
- Richard O'Brien
- Richard Parker
- Rina Mardania
- Rita Ghatala
- Robert Ballantine
- Robert Campbell
- Robert Luder
- Robert Whiting
- Robyn Creeden
- Rohan Simon
- Rosanna Fong
- Rosemary Anderson
- Rowilson Jarapa
- Rustam Al-Shahi Salman
- Ruth Bellfield
- Ruth Davies
- Ruth Fennelly
- Ruth Fraser
- Ruth Fraser
- Ruth Graham
- Ruth Paulton
- Ruwan Parakramawansha
- Sagal Kullane
- Sageet Amlani
- Saikat Dhar
- Saima Sheikh
- Saira Sattar
- Sajjad Anwar
- Sakthivel Sethuraman
- Sally Marshall
- Sally Moseley
- Salwa El Tawil
- Sam Ellis
- Sam King
- Samantha Clarke
- Samantha Keenan
- Samantha Seagrave
- Samantha Stafford
- Samantha Stafford
- Sammie Qureshi
- Sandeep Ankolekar
- Sandip Ghosh
- Sandra Leason
- Sandra Nelson
- Sankaranarayanan Ramachandran
- Santhosh Subramonian
- Sarah Board
- Sarah Brown
- Sarah Caine
- Sarah Crisp
- Sarah Cuddy
- Sarah Finlay
- Sarah Horton
- Sarah O'Toole
- Sarah Ross
- Sarah Stevenson
- Sarah Thomas
- Sarah Thornthwaite
- Sarah Trippier
- Sarah Wilson
- Sean Mcauley
- Senthil Raghunathan
- Seona Burgess
- Shagufta Khan
- Shahrzad Shahmehri
- Shanni McDonald
- Shannon Amoils
- Sharon Johnson
- Sharon Storton
- Sharon Tysoe
- Sheila Mashate
- Sheila Nyabadza
- Shelley Treadwell
- Shez Feerick
- Shrivakumar Krishnamoorthy
- Shuja Punekar
- Shuna Egerton
- Shyam Kelavkar
- Silvie Davies
- Simon Hervey
- Simon Sharpe
- Simon Smith
- Simone Ivatts
- Sindhu Rashmi
- Siobhan Kelly
- Sissy Ispoglou
- Skarlet Markova
- Skelton Miriam
- Sofia Dima
- Sonia Raj
- Sophie Newton
- Sreeman Andole
- Srikanth Chenna
- Stacey Valentine
- Stefan Schwarz
- Steiner
- Steinhubl
- Stephanie Jones
- Stephanie Lee
- Stephanie McCann
- Stephanie Stevens
- Stephen Duberley
- Stephen Woodward
- Steve Buckle
- Steve Buckle
- Stuart Maguire
- Stuart Symonds
- Sue Evans
- Sue Lyjko
- Suheil Ponnambath
- Suja Cherian
- Sujata Blane
- Sulaiman Sultan
- Susan Clayton
- Susan Crawford
- Susan Downham
- Susan Maiden
- Susan McDonald
- Susan O'Connell
- Susan Pound
- Susan Szabo
- Susan Thompson
- Susan Tucker
- Susan White
- Susannah Walker
- Suzanne Lucas
- Suzanne Ragab
- Suzanne Tauro
- Swapna Kunhunny
- Sweni Shah
- Syed Haider
- Tajammal Zahoor
- Talal Al-Mayhani
- Talat Anjum
- Tanya Ingram
- Tara Lawrence
- Tarn Nozedar
- Tatiana Garcia
- Tatjana Roganova
- Temi Adedoyin
- Teo
- Teresa Beaty
- Teresa Thompson
- Terry Jones
- Thayalini Loganathan
- Thomas Gattringer
- Thomas Harrison
- Tim Cassidy
- Timothy England
- Timothy Webster
- Toby Black
- Tolu Adesina
- Tom Hughes
- Tom Webb
- Tony Rudd
- Tracey Cosier
- Tracey Dobson
- Tracy Fuller
- Tracy Marsden
- Tressy Pitt-Kerby
- Una Poultney
- Ursula Schulz
- Usman Khan
- Uzma Khan
- Val Jones
- Valerie Gott
- Valerie Hogg
- van Asch
- Vanessa Pressly
- Varthi Sukdeo
- Vasileios Papavasileiou
- Venetia Vettimootal Johnson
- Vera Cvoro
- Vicky Taylor
- Victoria Adell
- Victoria Little
- Victoria O'Loughlin
- Victoria Sutton
- Victoria Tilley
- Vidya Baliga
- Vinh Nguyen
- Vinodh Krishnamurthy
- Wilma Smith
- WN Whiteley
- Wong
- Wood
- Xuya Huang
- Yasmin Harrington-Davies
- Yogish Joshi
- Yogish Pai
- Yolanda Baird
- Zhe Law
- Zin Naing
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/05/2019
- Field of study
BACKGROUND: Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events. METHODS: The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627). FINDINGS: Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29-146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0- 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25-1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39-1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65-1·60]; p=0·92). INTERPRETATION: These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention. FUNDING: British Heart Foundation
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- Author
- Abani O.
- Abbas A.
- Abbas F.
- Abbas M.
- Abbasi S.
- Abbass H.
- Abbott A.
- Abdallah N.
- Abdelaziz A.
- Abdelfattah M.
- Abdelqader B.
- Abdul Rasheed A.
- Abdul B.
- Abdul-Kadir R.
- Abdul-Raheem R.
- Abdulakeem A.
- Abdulmumeen A.
- Abdulshukkoor N.
- Abdusamad K.
- Abed El Khaleq Y.
- Abedalla M.
- Abeer Ul Amna A.
- Abernethy K.
- Abo-Leyah H.
- Aboaba A.
- Abou-Haggar A.
- Abouibrahim M.
- Abraham M.
- Abraham T.
- Abraheem A.
- Abrams J.
- Abu H.-J.
- Abu-Arafeh A.
- Abubacker S.M.
- Abung A.
- Aceampong Y.
- Achara A.
- Acharya D.
- Acheampong S.
- Acheson J.
- Acosta A.
- Acton C.
- Adabie-Ankrah J.
- Adam F.
- Adam M.
- Adamali H.
- Adams C.
- Adams C.
- Adams K.
- Adams R.
- Adams T.
- Adcock K.
- Addai J.
- Adebiyi A.
- Adegoke K.
- Adell V.
- Adenwalla S.
- Adesemoye O.A.
- Adewunmi E.O.
- Adeyemi J.
- Adhikary R.
- Adkins G.
- Adnan A.
- Aeron-Thomas J.
- Affleck D.
- Afnan C.
- Afridi M.
- Aftab Z.A.
- Agarwal M.
- Agbeko R.
- Agbo C.
- Agent P.
- Aggarwal S.
- Aghababaie A.
- Ahamed Sadiq S.
- Ahammed Nazeer M.H.
- Ahmad M.
- Ahmad S.
- Ahmed Ali R.
- Ahmed A.
- Ahmed B.
- Ahmed F.
- Ahmed H.
- Ahmed I.
- Ahmed I.
- Ahmed K.
- Ahmed L.
- Ahmed M.
- Ahmed M.C.
- Ahmed M.S.
- Ahmed N.
- Ahmed N.
- Ahmed O.
- Ahmed R.
- Ahmed R.A.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.H.
- Ahmer S.
- Ail D.
- Ainsworth M.
- Aissa M.
- Aitken L.
- Ajay B.
- Ajibode A.
- Ajmi A.
- Akhtar N.
- Akhtar N.
- Akili S.
- Akindolie O.
- Akinfenwa Y.
- Akinkugbe O.
- Aktinade O.
- Al Aaraj A.
- Al Balushi A.
- Al Dakhola M.
- Al Swaifi A.
- Al-Abadi E.
- Al-Asadi A.
- Al-Fori J.
- Al-Hakim B.
- Al-Hity S.
- Al-Jibury M.
- Al-Juboori S.
- Al-Khalil M.
- Al-Moasseb H.
- Al-Obaidi M.
- Al-Rabahi A.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Shamkhani W.
- Al-Sheklly B.
- Aladangady N.
- Alam A.
- Alam S.
- Alatzoglou K.
- Albert P.
- Albon L.
- Alcorn G.
- Alcorn S.
- Aldana A.
- Alderdice D.
- Aldouri R.
- Aldridge J.
- Aldridge N.
- Alegria A.
- Alexander A.
- Alexander J.
- Alexander P.D.G.
- Alford C.
- Alghazawi L.
- Ali A.
- Ali A.
- Ali F.R.
- Ali J.
- Ali M.
- Ali M.
- Ali N.
- Ali O.
- Ali S.
- Ali S.
- Alina A.
- Aliyuda F.
- Alizaedeh K.
- Alkhusheh M.
- Allan F.
- Allanson A.
- Allcock R.
- Allen E.
- Allen K.
- Allen L.
- Allen P.
- Allen R.
- Allen S.
- Allen S.
- Allen S.
- Allison K.
- Allman B.
- Allsop L.
- Alomari L.
- Alshaer I.
- Altaf S.
- Alvarez M.
- Alzetani M.
- Amamou S.
- Amar N.
- Ambalavanan S.
- Ambler S.-J.
- Ambrogetti R.
- Ambrose C.
- Ameen A.
- Amenyah K.
- Amezaga M.R.
- Amin A.
- Amin A.
- Amin K.
- Amin S.
- Amin T.
- Amjad A.
- Amjad N.
- Amosun V.
- Amsha K.
- Amy P.
- Anand A.
- Anandappa S.
- Anderson J.
- Anderson L.
- Anderson M.
- Anderson N.
- Anderson R.
- Anderson R.
- Anderson W.
- Andreou P.
- Andrews A.
- Andrews A.
- Andrews J.
- Aneke K.
- Ang A.
- Ang W.W.
- Angel T.
- Angela A.
- Angelini P.
- Anguvaa L.
- Anichtchik O.
- Anim-Somuah M.
- Aniruddhan K.
- Anne Ledingham M.
- Annett J.
- Anstey P.J.
- Anstey R.
- Anthony A.
- Anthony-Pillai A.
- Antill P.
- Antonina Z.
- Anu V.
- Anwar M.
- Apostolopoulos A.
- Appleyard D.
- Aquino M.F.
- Araba B.
- Aransiola S.
- Araujo M.
- Archer A.
- Archer D.
- Archer S.
- Ardley C.
- Arias A.-M.
- Arimoto R.
- Arkley C.
- Armah C.
- Armata I.
- Armitage A.
- Armstrong C.
- Armstrong M.
- Armstrong S.
- Armtrong P.
- Arndt H.
- Arnison-Newgass C.
- Arnold D.
- Arnold R.
- Arora D.
- Arora K.
- Arora P.
- Arora R.
- Arter A.
- Arya A.
- Arya R.
- Asandei D.
- Asghar A.
- Ashbrook-Raby C.
- Ashby H.
- Ashcroft J.
- Ashcroft J.
- Ashcroft S.
- Asher D.
- Ashfaq A.
- Ashish A.
- Ashman-Flavell S.
- Ashok S.
- Ashour A.-E.-A.
- Ashraf M.Z.
- Ashraf S.
- Ashraq M.B.
- Ashton D.
- Ashton S.
- Ashworth A.
- Ashworth R.
- Aslam A.
- Asogan H.
- Asrar A.
- Assaf O.
- Astin-Chamberlain R.
- Athorne D.
- Atkins B.
- Atkins C.
- Atkins S.
- Atkinson J.
- Atkinson V.
- Atraskiewicz B.
- Attia A.A.
- Atugonza R.
- Aubrey P.
- Aujayeb A.
- Aung A.C.T.
- Aung H.
- Aung K.T.
- Aung Y.
- Aung Z.M.
- Austin E.
- Austin K.
- Auwal A.
- Avery M.
- Avis J.
- Aviss G.
- Avram C.
- Avram P.
- Awadzi G.
- Awan A.
- Aya A.
- Ayaz E.
- Ayers A.
- Azam J.
- Azharuddin M.
- Aziz G.
- Aziz N.
- Azkoul A.
- Azman Shah A.
- Azzopardi G.
- Azzoug H.
- Babatunde F.
- Babi M.
- Babiker B.
- Babington G.
- Babirecki M.
- Babores M.
- Babs-Osibodu A.O.
- Bacciarelli S.
- Bachar R.
- Bacon G.
- Bacon J.
- Badal B.
- Badhan G.R.
- Badhrinarayanan S.
- Bae J.P.
- Bafekr S.
- Baggaley A.
- Baggott A.
- Bagley G.
- Bagmane D.
- Bagshaw L.
- Bahadori K.
- Bailey J.
- Bailey K.
- Bailey L.
- Bailey L.
- Bailey M.
- Bailey P.
- Bailey S.
- Baillie H.
- Baillie J.K.
- Bain J.
- Bains V.
- Baird D.
- Baird S.
- Baird T.
- Baird Y.
- Bajandouh A.
- Baker E.
- Baker J.
- Baker J.
- Baker K.
- Baker R.
- Baker T.-A.
- Baker V.
- Baker-Moffatt M.
- Bakere H.
- Bakerly N.
- Bakhtiar N.
- Bakoulas P.
- Balachandran N.
- Balan A.
- Balaskas T.
- Balasubramaniam M.
- Balcombe A.
- Baldwin A.
- Baldwin A.
- Baldwin C.
- Baldwin D.
- Baldwin-Jones R.
- Balfour J.
- Ball C.
- Ballard K.
- Balluz I.
- Balmforth C.
- Balogh E.
- Baluwala A.
- Bambridge G.
- Bamford A.
- Bamford A.
- Bamford P.
- Bamgboye A.
- Bancroft E.
- Bancroft H.
- Bancroft T.
- Banda J.
- Bandaru K.
- Bandi S.
- Bandla N.
- Bandyopadhyam S.
- Banerjee A.
- Banerjee R.
- Banks H.
- Banks L.
- Banks P.
- Bannister O.
- Banton L.
- Baptist M.
- Baqai T.
- Baral A.M.
- Baramova D.
- Barber R.
- Barbon E.
- Barbosa M.
- Barbour J.
- Barclay A.
- Barclay C.
- Bardsley G.
- Bareford S.
- Bari S.
- Barker A.
- Barker D.
- Barker H.
- Barker J.B.
- Barker L.
- Barker O.
- Barker-Williams K.
- Barkha S.
- Barla J.
- Barlow G.
- Barlow R.
- Barlow V.
- Barnacle J.
- Barnard A.
- Barnes D.
- Barnes N.
- Barnes T.
- Barnetson C.
- Barnett A.
- Barnett M.
- Barnett-Vanes A.
- Barnsley W.
- Barr A.
- Barr D.
- Barratt S.
- Barrera M.
- Barrett A.
- Barrett F.
- Barrett J.
- Bartholomew J.
- Bartlett C.
- Bartlett G.
- Barton G.
- Barton J.
- Barton L.
- Barton R.
- Baruah R.
- Baryschpolec S.
- Bashyal A.
- Basker B.
- Basoglu A.
- Bassett G.
- Bassett J.
- Bassford C.
- Bassoy B.
- Bastion V.
- Basumatary A.
- Bate T.
- Bateman H.J.
- Bateman K.
- Bateman V.
- Bates E.
- Bates H.
- Bates M.
- Bates S.
- Batham S.
- Batista A.
- Batla A.
- Batra D.
- Batty H.
- Batty T.
- Baum M.
- Bautista C.
- Bawa F.
- Bawani F.S.
- Bax S.
- Baxter M.
- Baxter N.
- Baxter Z.
- Bayes H.
- Bazari F.
- Bazaz R.
- Bazli A.
- Beacham L.
- Beadles W.
- Beak P.
- Beale A.
- Bearpark J.
- Beaumont K.
- Beaumont-Jewell D.
- Beaver T.
- Beavis S.
- Beazley C.
- Beck S.
- Beckett V.
- Beckitt R.
- Beddall H.
- Beddows S.
- Beeby D.
- Beech G.
- Beecroft M.
- Beer S.
- Beety J.
- Bega G.
- Begg A.
- Begg S.
- Beghini S.
- Begum A.
- Begum S.
- Begum S.
- Behan T.
- Beharry J.
- Behrouzi R.
- Beishon J.
- Beith C.
- Belcher J.
- Belfield H.
- Belfield K.
- Belgaumkar A.
- Bell D.
- Bell G.
- Bell G.
- Bell J.L.
- Bell L.
- Bell L.
- Bell N.
- Bell P.
- Bell S.
- Bellamu J.
- Bellamy M.
- Bellini A.
- Bellis A.
- Bellis F.
- Bendall L.
- Benesh N.
- Benetti N.
- Benham L.
- Benison-Horner G.
- Bennett A.
- Bennett C.
- Bennett G.
- Bennett K.
- Bennett L.
- Bennett S.
- Bennion K.
- Benson V.
- Bentley A.
- Bentley J.
- Benton I.
- Beranova E.
- Beresford M.
- Bergin C.
- Bergstrom M.
- Bernatoniene J.
- Berriman T.
- Berry Z.
- Best K.
- Bester A.-M.
- Beuvink Y.
- Bevan E.
- Bevins S.
- Bewick T.
- Bexley A.
- Beyatli S.
- Beynon F.
- Bhadi A.
- Bhagani S.
- Bhakta S.
- Bhalla R.
- Bhandal K.
- Bhandal K.
- Bhandari A.
- Bhandari S.
- Bhanot A.
- Bhanot R.
- Bhat P.
- Bhatia N.
- Bhatnagar R.
- Bhatt K.
- Bhayani J.
- Bhojwani D.
- Bhuiyan S.
- Bibby A.
- Bibi F.
- Bibi N.
- Bibi S.
- Bicanic T.
- Bidgood S.
- Bigg J.
- Biggs S.
- Biju A.
- Bikov A.
- Billingham S.
- Billings J.
- Binney M.
- Binns A.
- BinRofaie M.
- Bintcliffe O.
- Birch C.
- Birch J.
- Birchall K.
- Bird S.
- Bird S.
- Birt M.
- Bishop K.
- Bishop L.
- Bishop L.
- Bisnauthsing K.
- Biswas N.
- Biuk S.
- Blachford K.
- Black E.
- Black H.
- Black K.
- Black M.
- Black P.
- Blackgrove H.
- Blackledge B.
- Blackler J.
- Blackley S.
- Blackman H.
- Blackstock C.
- Blackwood L.
- Blakemore F.
- Blamey H.
- Bland A.
- Blane S.
- Blankley S.
- Blaxill P.
- Blaylock K.
- Blazeby J.
- Blencowe N.
- Bloom B.
- Bloomfield J.
- Bloss A.
- Bloxham H.
- Blundell L.
- Blunsum A.
- Blunt M.
- Blyth I.
- Blyth K.
- Blythe A.
- Blythe K.
- Boampoaa M.
- Bobie B.
- Bobruk K.
- Bodalia P.
- Bodasing N.
- Bodenham T.
- Boehmer G.
- Boffito M.
- Bohmova K.
- Bokhandi S.
- Bokhar M.
- Bokhari S.
- Bokhari S.
- Bokhari S.O.
- Boles A.
- Bond C.
- Bond H.
- Bond S.
- Bond T.
- Bone A.
- Boniface G.
- Bonney L.
- Borbone J.
- Borman N.
- Bottrill F.
- Bough L.
- Boughton H.
- Boult Z.
- Bourke M.
- Bourke S.
- Bourne M.
- Bousfield R.
- Boustred L.
- Bowes A.
- Bowes A.
- Bowker P.
- Bowman L.
- Bowman S.
- Bowmer R.
- Bowring A.
- Bowyer H.
- Boyd J.
- Boyd L.
- Boyle N.
- Boyle P.
- Boyle R.
- Boyles L.
- Brace L.
- Bradder J.
- Bradley C.J.
- Bradley P.
- Bradley P.
- Bradley P.
- Bradley-Potts J.
- Bradshaw L.
- Bradshaw Z.
- Brady R.
- Brady S.
- Braganza D.
- Branch M.
- Brankin-Frisby T.
- Brannigan J.
- Brassington L.
- Brattan S.
- Bray F.
- Bray N.
- Brazil M.
- Brear L.
- Brear T.
- Brearey S.
- Bremner L.
- Brend M.
- Bretland G.
- Brewer C.
- Bridge H.
- Bridgwood G.
- Brigham S.
- Bright J.
- Brightling C.E.
- Brimfield L.
- Brinkworth E.
- Brittain-Long R.
- Britten V.
- Broad L.
- Broad S.
- Broadhurst R.
- Broadley A.
- Broadway M.
- Brockelsby C.
- Brocken M.
- Brockley T.
- Brodsky M.
- Brogan F.
- Brohan L.
- Brokke F.
- Brolly J.
- Bromley D.
- Brooke-Ball H.
- Brooker V.
- Brookes M.
- Brooks A.
- Brooks K.
- Brooks N.
- Brooks P.
- Brooks R.
- Brooks S.
- Broomhead N.
- Broughton C.
- Broughton N.
- Brouns M.
- Brown A.
- Brown A.
- Brown C.
- Brown C.
- Brown E.
- Brown H.
- Brown J.
- Brown L.
- Brown N.
- Brown P.
- Brown R.
- Brown R.
- Brown S.
- Brown T.
- Browne B.
- Browne C.
- Browne D.
- Browne M.
- Brownlee S.
- Brraka A.
- Bruce D.
- Bruce J.
- Bruce M.
- Brudlo W.
- Brunskill N.
- Brunton A.
- Brunton M.
- Bryan M.
- Bryant M.
- Buazon A.
- Buch M.H.
- Buchanan R.
- Buche D.
- Buck A.
- Buckland M.
- Buckley L.
- Buckley P.
- Buckley S.
- Buckman C.
- Buckmire K.
- Bugg G.
- Bujazia R.
- Bukhari M.
- Bukhari S.
- Bulbulia R.
- Bull A.
- Bull D.
- Bull R.
- Bull T.
- Bulteel N.
- Bumunarachchi K.
- Bungue-Tuble R.
- Burchett C.
- Burda D.
- Burden C.
- Burden T.G.
- Burgess M.
- Burgess R.
- Burgess S.
- Burgett P.
- Burman A.
- Burnard S.
- Burnett C.
- Burns A.
- Burns A.
- Burns C.
- Burns J.
- Burns K.
- Burrage D.
- Burrows K.
- Burston C.
- Burton B.
- Burton F.
- Burton M.
- Butcher D.
- Butler A.
- Butler J.
- Butler J.
- Butler J.
- Butler P.
- Butler S.
- Butt A.-T.
- Butt M.M.
- Butterworth C.
- Butterworth-Cowin N.
- Buttery R.
- Buttle T.
- Button H.
- Buttress D.
- Byrne J.
- Byrne W.
- Byrne-Watts V.
- Byworth E.
- Cabandugama A.
- Cade R.
- Cadwgan A.
- Cairney D.
- Calderwood J.
- Caldow D.
- Calisti G.
- Callaghan D.
- Callaghan J.
- Callens C.
- Callum D.
- Calver C.
- Cambell-Kelly M.
- Camburn T.
- Cameron D.R.
- Cameron E.
- Cameron F.
- Cameron S.
- Camm C.
- Cammack R.F.D.
- Campbell Hewson Q.
- Campbell A.
- Campbell A.
- Campbell B.
- Campbell B.
- Campbell D.
- Campbell H.
- Campbell H.
- Campbell J.
- Campbell M.
- Campbell R.
- Campbell W.
- Camsooksai J.
- Canclini L.
- Candido S.M.
- Candlish J.
- Caneja C.
- Cann J.
- Cannan R.
- Cannon E.
- Cannon M.
- Cannon P.
- Cannons V.
- Cantliff J.
- Caplin B.
- Capocci S.
- Caponi N.
- Capp A.
- Capps-Jenner A.
- Capstick T.
- Carboo I.
- Cardwell M.
- Carey R.
- Carley S.
- Carlin T.
- Carmichael S.
- Carnahan M.
- Caroline C.
- Carpenter J.
- Carr S.
- Carrasco A.
- Carrington Z.
- Carroll P.
- Carstairs A.
- Carter J.
- Carter M.
- Carter P.
- Carter P.
- Carter S.
- Cartwright D.
- Cartwright J.-A.
- Carty C.
- Carty S.
- Carungcong J.
- Casey S.
- Cassells A.
- Cassimon B.
- Castiello T.
- Castle G.
- Castles B.
- Caswell M.
- Catana A.M.
- Cate H.
- Cathcart S.
- Cathie K.
- Catley C.
- Catlow L.
- Caudwell M.
- Caulfield J.
- Cavazza A.
- Cave L.
- Cavinato S.
- Cawa F.
- Cawley K.
- Caws C.
- Cendl H.
- Century H.
- Cernova J.
- Cesay M.
- Cetti E.
- Chabane S.
- Chablani M.
- Chabo C.
- Chadwick D.
- Chadwick J.
- Chadwick R.
- Chakkarapani E.
- Chakraborty A.
- Chakraborty M.
- Chakravorty M.
- Chalmers J.
- Chalmers R.
- Chamberlain G.
- Chamberlain S.
- Chambers E.
- Chambers J.
- Chambers L.
- Chambers N.
- Chan A.
- Chan C.
- Chan C.
- Chan E.
- Chan K.
- Chan K.
- Chan P.
- Chan R.P.-C.
- Chan X.H.
- Chandler C.
- Chandler H.
- Chandler K.J.
- Chandler S.
- Chandler Z.
- Chandra S.
- Chandran N.
- Chandrasekaran B.
- Chang Y.
- Chaplin J.
- Chapman G.
- Chapman J.
- Chapman K.
- Chapman L.
- Chapman L.
- Chapman P.
- Chapman T.
- Chappell L.
- Chapple L.
- Charalambou A.
- Charles B.
- Charlton D.
- Chatar K.
- Chatha C.
- Chaube R.
- Chaudhary M.Y.N.
- Chaudhry I.
- Chaudhuri N.
- Chaudhury M.
- Chauhan A.
- Chauhan R.S.
- Chauhan V.
- Chavasse N.
- Chawla V.
- Cheater L.
- Cheaveau J.
- Cheeld C.
- Cheeseman M.
- Chen F.
- Chen H.M.
- Chen T.
- Cheng L.Y.
- Cheng Z.
- Chenoweth H.
- Cheong C.H.
- Cherian S.
- Cherrie M.
- Cheshire H.
- Chesterson B.
- Cheung C.K.
- Cheung E.
- Cheung M.
- Cheyne C.
- Chhabra S.
- Chia W.L.
- Chiang E.
- Chiapparino A.
- Chicano R.
- Chikwanha Z.A.
- Chilcott S.
- Chimbo P.
- Chin K.
- Chin W.J.
- Chineka R.
- Chingale A.
- Chiroma V.
- Chisem H.
- Chisenga C.
- Chisnall B.
- Chiswick C.
- Chita S.
- Chitalia N.
- Chiu M.
- Chivima B.
- Chmiel C.
- Choi S.
- Choon Kon Yune W.
- Choudhary V.
- Choudhury S.
- Chow B.-L.
- Chowdhury M.
- Chowdhury S.
- Christenssen V.
- Christian P.
- Christides A.
- Christie F.
- Christmas D.
- Christopherson T.
- Christy M.
- Chrysostomou P.
- Chua Y.
- Chudgar D.
- Chudleigh R.
- Chukkambotla S.
- Chukwu M.E.
- Chukwulobelu I.
- Chung C.Y.
- Church E.
- Church S.R.
- Churchill D.
- Cianci N.
- Cicconi P.
- Cinardo P.
- Cipinova Z.
- Cipriano B.
- Clamp S.
- Clapham M.
- Clare E.
- Clare S.
- Clark A.
- Clark C.
- Clark D.
- Clark F.
- Clark G.
- Clark J.
- Clark K.
- Clark K.
- Clark L.
- Clark L.
- Clark M.
- Clark P.
- Clark R.
- Clark T.
- Clark Z.
- Clarke A.
- Clarke H.
- Clarke P.
- Clarke R.
- Clarke R.
- Clarke S.
- Clarke S.
- Clarke T.
- Claxton A.
- Clay K.
- Clayton E.
- Clayton O.
- Clayton-Smith J.
- Cleaver C.
- Clemente de la Torre C.
- Clements J.
- Clements S.
- Clifford R.
- Clifford S.
- Clive A.
- Clueit S.
- Clyne A.
- Coakley M.
- Coakley P.G.L.
- Coates T.
- Cobain K.
- Cochrane A.
- Cochrane P.
- Cockerell M.
- Cockerill H.
- Cocks S.
- Codling R.
- Coe A.
- Coetzee S.
- Coey D.
- Cohen D.
- Cohen J.
- Cohen O.
- Cohn M.
- Coke L.
- Coker O.
- Colbeck N.
- Colbert R.
- Cole E.
- Cole J.
- Cole J.
- Cole J.
- Cole R.
- Coleman G.
- Coleman M.
- Coles H.
- Colin M.
- Colino-Acevedo A.
- Colley J.
- Collier D.
- Collier H.
- Collini P.
- Collins E.
- Collins J.
- Collins J.
- Collins N.
- Collins S.
- Collins V.
- Collinson A.
- Collinson B.
- Collinson J.
- Collis M.
- Colmar M.
- Colton H.E.
- Colton J.
- Colville K.
- Colvin C.
- Colwell R.
- Combes E.
- Comer D.
- Comerford A.
- Concannon D.
- Condliffe R.
- Connell L.
- Connell N.
- Connelly K.
- Connolly G.
- Connor E.
- Conroy A.
- Conteh V.
- Convery R.
- Conway F.
- Conway G.
- Conway R.
- Conyngham J.-A.
- Cook C.
- Cook E.
- Cook G.
- Cook H.
- Cook J.
- Cooke D.
- Cooke G.
- Cooke K.
- Cooke T.
- Cooper A.
- Cooper C.
- Cooper D.
- Cooper H.
- Cooper J.
- Cooper J.
- Cooper J.
- Cooper L.
- Cooper N.
- Cooper R.
- Cope T.
- Corbet S.
- Corbett C.
- Corcoran J.
- Cordell C.
- Cordle J.
- Corfield A.
- Corless J.
- Corlett A.
- Cornwell J.
- Cornwell M.
- Corogeanu D.
- Corredera M.
- Corrigan R.
- Corser R.
- Cosgrove D.
- Cosier T.
- Costa P.
- Coston C.
- Cotgrove S.
- Coton Z.
- Cottam L.-J.
- Cotter R.
- Cotterill D.
- Cotton C.
- Cotton K.
- Coull A.
- Coulson J.
- Counsell D.
- Counter D.
- Coupland C.
- Courtney E.
- Courtney J.
- Cousins R.
- Cowan A.
- Cowan E.
- Cowell R.
- Cowen L.
- Cowman S.
- Cowton A.
- Cox E.
- Cox G.
- Cox K.
- Cox M.
- Coy K.
- Craig B.
- Craig V.
- Craighead F.
- Cramp M.
- Crause J.
- Crawford A.
- Crawford A.
- Crawford E.
- Crawford I.
- Crawforth R.
- Crawshaw S.
- Creagh-Brown B.
- Creamer A.
- Cremona J.
- Cremona S.
- Cresswell J.
- Cribb M.
- Crichton C.
- Crilly D.
- Crisp L.
- Crisp N.
- Crocombe D.
- Croft M.
- Crooks J.
- Crosby H.
- Cross T.
- Crothers A.
- Crotty S.
- Crouch S.
- Crow M.
- Crowder A.
- Crowley K.
- Crowley T.
- Croysdill R.
- Cruickshank C.
- Cruickshank C.
- Cruickshank I.
- Cruise J.
- Cruz Cervera T.
- Cruz C.
- Cryans D.
- Cui G.
- Cui H.
- Cullen L.
- Cummings-Fosong G.
- Cundall M.
- Cunliffe V.
- Cunningham L.
- Cunningham N.
- Cunningham N.
- Cupitt J.
- Curgenven H.
- Curran D.
- Curran S.
- Currie C.
- Currie J.
- Currie S.
- Curtis J.
- Curtis K.
- Curtis O.
- Curtis T.
- Cuthbertson R.
- Cutler S.
- Czekaj M.
- Czylok P.
- D Ramdin D.
- D'Costa P.
- da Rocha J.
- Dagens A.
- Daggett H.
- Daglish J.
- Dahiya S.
- Dale A.
- Dale K.
- Dale M.
- Dale S.
- Dales J.
- Dalgleish H.
- Dallow H.
- Dalton D.
- Daly Z.
- Damian E.
- Danga A.
- Daniel A.
- Daniel P.
- Daniels A.
- Dann A.
- Danso-Bamfo S.
- Daoud N.
- Darbyshire A.
- Darbyshire J.
- Dargan P.
- Dark P.
- Darlington K.
- Darton T.
- Darylile G.
- Das M.
- Das S.
- Daschel M.
- Dasgin J.
- Datta D.
- Daunt A.
- Davenport E.
- Davey M.
- Davey M.
- Davey M.
- David M.
- Davidson A.
- Davidson L.
- Davidson N.D.
- Davidson R.
- Davies A.
- Davies A.
- Davies A.
- Davies A.
- Davies A.
- Davies C.
- Davies C.
- Davies C.
- Davies D.
- Davies E.
- Davies F.
- Davies H.
- Davies J.
- Davies J.
- Davies K.
- Davies K.
- Davies K.
- Davies L.
- Davies M.
- Davies M.
- Davies N.
- Davies O.
- Davies P.
- Davies R.
- Davies R.
- Davies R.
- Davies S.
- Davies S.
- Davis A.
- Davis G.
- Davis I.
- Davis J.-A.
- Davis K.
- Davis P.
- Davison A.
- Davy M.
- Dawe C.
- Dawe H.
- Dawkins M.
- Dawson D.
- Dawson E.
- Dawson J.
- Dawson S.
- Dawson T.
- Daxter A.
- Day A.
- Day J.
- Day J.
- de Fonseka D.
- Dey V.
- Vara S.
- Vardy S.J.
- Varghese A.
- Varghese M.
- Varney W.
- Varnier G.
- Vasadi V.
- Vass O.
- Vasu V.
- Vasudevan V.
- Vatish M.
- Vayalaman H.
- Vaz C.
- Veale N.
- Veerasamy S.
- Velan B.
- Velankar S.
- Velauthar L.
- Veli N.
- Vella N.
- Velusamy A.
- Venables I.
- Venditti M.
- Veniard D.
- Venkataramakrishnan R.
- Venn R.
- Venn R.
- Ventilacion L.
- Vere J.
- Veres M.
- Vergnano S.
- Verling W.
- Verma A.
- Vernall R.
- Vernon B.
- Vertue M.
- Verula J.
- Vethanayagam N.
- Veys L.
- Vickers C.
- Victor S.
- Vidler J.
- Vijayakumar B.
- Vijayaraghavan Nalini V.W.
- Vilcinskaite B.
- Vilimiene N.
- Vinall L.
- Vinay S.
- Vinayakarao L.
- Vincent R.
- Vincent R.
- Virdee P.
- Virgilio E.
- Virk A.M.
- Visentin E.
- Visuvanathan J.
- Vithian K.
- Vittoria S.
- Vlad E.
- Vlies B.
- Vuylsteke A.
- Vyras E.
- Wach R.
- Wadams B.
- Wadd S.
- Waddington N.
- Wadsworth K.
- Wafa S.E.I.
- Wagstaff D.
- Wagstaff L.
- Wahab D.
- Wahbi Z.
- Waheed Adigun A.
- Waidyanatha S.
- Wake R.
- Wakefield A.
- Wakeford W.
- Wakinshaw F.
- Walden A.
- Walding L.
- Waldron A.
- Walker G.
- Walker H.
- Walker I.
- Walker K.
- Walker K.
- Walker L.
- Walker M.
- Walker O.
- Walker R.
- Walker R.
- Walker S.
- Wallbutton R.
- Wallen J.
- Wallendszus K.
- Waller A.
- Waller R.
- Wallis G.
- Wallis L.
- Walsh D.
- Walsh E.
- Walsh L.
- Walstow D.
- Walter D.
- Walters A.
- Walters H.
- Walters J.
- Walters J.
- Walton E.
- Walton L.
- Walton O.
- Walton S.
- Walton S.
- Wan M.
- Wan T.
- Wands M.
- Wane R.
- Wang F.
- Wang N.
- Wang R.
- Warbrick D.
- Warburton S.
- Ward D.
- Ward E.
- Ward J.
- Ward L.
- Ward N.
- Ward R.
- Ward T.
- Ward T.
- Warden S.A.
- Wardle A.
- Wardle K.
- Wardle S.
- Wardy H.
- Waring S.
- Warmington J.
- Warner B.
- Warner C.
- Warnock L.
- Warran S.
- Warren J.
- Warren L.
- Warren Y.
- Warren-Miell H.
- Warwick G.
- Wassall H.
- Watchorn H.J.
- Waterfall H.
- Waters A.
- Waters D.
- Waterstone M.
- Watkins C.
- Watkins C.
- Watkins E.
- Watkins K.
- Watkins L.
- Watson A.
- Watson A.J.R.
- Watson E.
- Watson E.
- Watson P.
- Watson R.
- Watson R.
- Watters M.
- Watterson D.
- Watts D.
- Watts J.
- Watts M.
- Waugh V.
- Wayman E.
- Wazir A.
- Weatherhead M.
- Weatherly N.
- Webb H.
- Webb K.
- Webb K.
- Webb S.
- Websdale C.
- Webster D.
- Webster I.
- Webster T.
- Wee L.
- Weerakoon R.
- Weerasinghe T.
- Weeratunga J.
- Weetman M.
- Wei S.
- Weichert I.
- Welch H.
- Welch J.
- Welch L.
- Welch S.
- Weller S.
- Wellings L.
- Wells B.
- Wellstead S.
- Welsh B.
- Welsh R.I.
- Welters I.
- Welton R.
- Wentworth L.
- Wesseldine K.
- Wesson J.
- West M.
- West R.
- West R.
- West S.
- Western L.
- Westhead R.
- Weston H.
- Westwood A.
- Wetherill B.
- Wheaver S.
- Wheeler H.
- Whelan B.
- Whelband M.
- Whileman A.
- Whitcher A.
- White A.
- White B.
- White C.
- White D.
- White E.
- White J.
- White J.
- White K.
- White M.
- White N.
- White S.
- White S.
- White T.
- Whitehead C.
- Whitehouse A.
- Whitehouse C.
- Whitehouse T.
- Whiteley J.
- Whiteley S.
- Whitlingum G.
- Whitmore D.
- Whittaker E.
- Whittam L.
- Whittingham-Hirst A.
- Whittington A.
- Whittle H.
- Whittle R.
- Whyte S.
- Wiafe E.
- Wiblin L.
- Widdrington J.
- Wieboldt J.
- Wieringa H.
- Wiesender C.
- Wiffen L.
- Wight A.
- Wignall C.
- Wilcock D.
- Wilcock E.
- Wilcox L.
- Wild L.
- Wild S.
- Wilde M.
- Wilding P.
- Wildsmith T.
- Wileman J.
- Wiles D.
- Wiles J.
- Wiles K.
- Wilhelmsen E.
- Wiliams T.
- Wilkie J.
- Wilkin D.
- Wilkins H.
- Wilkins J.
- Wilkins S.
- Wilkinson I.
- Wilkinson L.
- Wilkinson N.
- Wilkinson S.
- Wilkinson S.
- Wilkinson T.
- Willetts S.
- Williams A.
- Williams A.
- Williams A.
- Williams A.
- Williams A.
- Williams C.
- Williams C.
- Williams C.V.
- Williams D.
- Williams G.
- Williams G.
- Williams G.
- Williams H.
- Williams J.
- Williams J.
- Williams J.
- Williams J.
- Williams K.
- Williams K.
- Williams M.
- Williams M.
- Williams P.
- Williams P.
- Williams R.
- Williams R.
- Williams S.
- Williams S.
- Williams S.
- Williams T.
- Williamson A.
- Williamson C.
- Williamson D.
- Williamson H.
- Williamson J.D.
- Williamson R.
- Willis E.
- Willis E.
- Willis H.
- Willis H.
- Willis J.
- Wills L.
- Willsher L.
- Willshire C.
- Willson F.
- Wilson A.
- Wilson A.
- Wilson A.
- Wilson B.
- Wilson E.
- Wilson J.
- Wilson K.
- Wilson K.
- Wilson L.
- Wilson M.
- Wilson T.
- Win M.
- Win T.T.
- Win W.Y.W.
- Winckworth L.
- Winder L.
- Winder P.
- Winham-Whyte K.
- Winmill H.
- Winn S.
- Winpenny C.
- Winslow H.
- Winter H.
- Winter J.
- Winter-Goodwin B.
- Wisdom S.
- Wise M.
- Wiselka M.
- Wiseman R.
- Wiseman S.
- Wishart S.
- Wissett H.
- Witele E.
- Withers N.
- Wittes J.
- Wixted D.
- Wodehouse T.
- Wolf W.
- Wolf-Roberts R.
- Wolff N.
- Wolffsohn K.
- Wolodimeroff E.
- Wolstencroft A.
- Wong A.
- Wong C.
- Wong C.-H.
- Wong E.
- Wong J.S.Y.
- Wong K.Y.
- Wong M.Y.
- Wong N.
- Wong S.
- Wood A.
- Wood C.
- Wood D.
- Wood F.
- Wood H.
- Wood J.
- Wood J.
- Wood K.
- Wood L.
- Wood L.
- Wood M.
- Wood S.
- Wood T.
- Woodfield R.
- Woodford C.
- Woodford E.
- Woodford J.
- Woodhead L.
- Woodhead T.
- Woodland P.
- Woodman M.
- Woods J.
- Woods K.
- Woods S.
- Woodward Z.
- Woolcock M.
- Wooldridge G.
- Woolf R.
- Woollard C.
- Woollard C.
- Woollen L.
- Woolley E.
- Woolley J.
- Wooodall K.
- Woosey D.
- Wootton D.
- Wootton J.
- Worley D.
- Worton S.
- Wraight J.
- Wray M.
- Wreford-Bush T.
- Wren J.
- Wren K.
- Wren L.
- Wrey Brown C.
- Wright C.
- Wright D.
- Wright F.
- Wright I.
- Wright L.
- Wright R.
- Wright R.
- Wright S.
- Wright T.
- Wroe C.
- Wroe H.
- Wu H.
- Wu P.
- Wu P.
- Wubetu J.
- Wulandari R.
- Wyatt C.
- Wyn-Griffiths F.
- Wynter I.
- Xavier B.
- Xhikola A.
- Xia Z.
- Yakubi M.
- Yan M.
- Yang F.
- Yang Y.
- Yanney M.
- Yap W.L.
- Yaqoob N.
- Yasmin S.
- Yates B.
- Yates D.
- Yates E.
- Yates H.
- Yates J.
- Yates M.
- Yearwood Martin C.
- Yein K.
- Yelnoorkar F.
- Yew P.
- Yip K.
- Ylquimiche Melly L.
- Ylquimiche L.
- Ynter I.
- Yong H.
- Yorke J.
- Youens J.
- Younes Ibrahim A.
- Young E.
- Young G.
- Young L.
- Yousafzar A.
- Youssouf S.
- Yousuf A.
- Yu C.
- Yung B.
- Yusef D.
- Yusef S.
- Yusuf I.
- Zafar A.-S.
- Zagalo S.
- Zaher S.
- Zahoor A.
- Zaki K.
- Zakir N.
- Zalewska K.
- Zamalloa A.
- Zaman M.
- Zaman R.
- Zaman S.
- Zamikula J.
- Zammit L.
- Zammit-Mangion M.
- Zebracki E.
- Zehnder D.
- Zeidan L.
- Zhao X.
- Zheng D.
- Zhu D.
- Zia M.
- Zibdeh O.
- Zill-E-Huma R.
- Zin E.T.
- Zinkin E.
- Zinyemba V.
- Zipitis C.
- Zmierczak A.
- Zubir A.
- Zuhra N.
- Zulaikha R.
- Zulfikar S.
- Zullo C.
- Zuriaga-Alvaro A.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/05/2021
- Field of study
Background:
In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.
Methods:
This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation (C-reactive protein ≥75 mg/L) were eligible for random assignment in a 1:1 ratio to usual standard of care alone versus usual standard of care plus tocilizumab at a dose of 400 mg–800 mg (depending on weight) given intravenously. A second dose could be given 12–24 h later if the patient's condition had not improved. The primary outcome was 28-day mortality, assessed in the intention-to-treat population. The trial is registered with ISRCTN (50189673) and ClinicalTrials.gov (NCT04381936).
Findings:
Between April 23, 2020, and Jan 24, 2021, 4116 adults of 21 550 patients enrolled into the RECOVERY trial were included in the assessment of tocilizumab, including 3385 (82%) patients receiving systemic corticosteroids. Overall, 621 (31%) of the 2022 patients allocated tocilizumab and 729 (35%) of the 2094 patients allocated to usual care died within 28 days (rate ratio 0·85; 95% CI 0·76–0·94; p=0·0028). Consistent results were seen in all prespecified subgroups of patients, including those receiving systemic corticosteroids. Patients allocated to tocilizumab were more likely to be discharged from hospital within 28 days (57% vs 50%; rate ratio 1·22; 1·12–1·33; p<0·0001). Among those not receiving invasive mechanical ventilation at baseline, patients allocated tocilizumab were less likely to reach the composite endpoint of invasive mechanical ventilation or death (35% vs 42%; risk ratio 0·84; 95% CI 0·77–0·92; p<0·0001).
Interpretation:
In hospitalised COVID-19 patients with hypoxia and systemic inflammation, tocilizumab improved survival and other clinical outcomes. These benefits were seen regardless of the amount of respiratory support and were additional to the benefits of systemic corticosteroids.
Funding:
UK Research and Innovation (Medical Research Council) and National Institute of Health Research
Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial
- Author
- Abani O.
- Abbas A.
- Abbas F.
- Abbas M.
- Abbasi S.
- Abbass H.
- Abbott A.
- Abdallah N.
- Abdelaziz A.
- Abdelfattah M.
- Abdelqader B.
- Abdo D.
- Abdul Rasheed A.
- Abdul B.
- Abdul-Kadir R.
- Abdul-Raheem R.
- Abdulakeem A.
- Abdulle A.
- Abdulmumeen A.
- Abdulshukkoor N.
- Abdusamad K.
- Abed El Khaleq Y.
- Abedalla M.
- Abeer Ul Amna A.U.A.
- Abernethy K.
- Abo-Leyah H.
- Aboaba A.
- Abou-Haggar A.
- Abouibrahim M.
- Abraham M.
- Abraham T.
- Abraheem A.
- Abrams J.
- Abu H.-J.
- Abu-Arafeh A.
- Abubacker S.M.
- Abung A.
- Aceampong Y.
- Achara A.
- Acharya D.
- Acheampong S.
- Acheson J.
- Acosta A.
- Acton C.
- Adabie-Ankrah J.
- Adair S.
- Adam F.
- Adam M.
- Adamali H.
- Adams C.
- Adams C.
- Adams K.
- Adams L.
- Adams R.
- Adams T.
- Adcock K.
- Addai J.
- Adebiyi A.
- Adegoke K.
- Adell V.
- Ademokun D.
- Adenwalla S.
- Adesemoye O.A.
- Adewunmi E.O.
- Adeyemi J.
- Adhikary R.
- Adkins G.
- Adnan A.
- Aeron-Thomas J.
- Affleck D.
- Affron D.
- Afnan C.
- Afridi M.
- Aftab Z.A.
- Agarwal M.
- Agbeko R.
- Agbo C.
- Agent P.
- Aggarwal S.
- Aghababaie A.
- Ahamed Sadiq S.
- Ahammed Nazeer M.H.
- Ahmad H.
- Ahmad M.
- Ahmad S.
- Ahmed Ali R.
- Ahmed A.
- Ahmed B.
- Ahmed F.
- Ahmed H.
- Ahmed I.
- Ahmed I.
- Ahmed K.
- Ahmed L.
- Ahmed M.
- Ahmed M.C.
- Ahmed M.S.
- Ahmed N.
- Ahmed N.
- Ahmed O.
- Ahmed R.
- Ahmed R.A.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.
- Ahmed S.H.
- Ahmer S.
- Ail D.
- Ainsworth M.
- Airoldi G.
- Aissa M.
- Aitken L.
- Ajay B.
- Ajeneye F.
- Ajibode A.
- Ajmi A.
- Akbar T.
- Akhtar N.
- Akhtar N.
- Akhtar N.
- Akili S.
- Akindolie O.
- Akinfenwa Y.
- Akinkugbe O.
- Akinpelu I.
- Akinwumiju O.
- Aktinade O.
- Al Aaraj A.
- Al Balushi A.
- Al Dakhola M.
- Al Swaifi A.
- Al-Abadi E.
- Al-Asadi A.
- Al-Asadi K.
- Al-Bayati M.
- Al-Fori J.
- Al-Hakim B.
- Al-Hity S.
- Al-Jibury M.
- Al-Juboori S.
- Al-Khalil M.
- Al-Moasseb H.
- Al-Obaidi M.
- Al-Rabahi A.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Shamkhani W.
- Al-Sheklly B.
- Aladangady N.
- Alam A.
- Alam S.
- Alatzoglou K.
- Albert P.
- Albon L.
- Alcorn G.
- Alcorn S.
- Aldana A.
- Alderdice D.
- Aldouri R.
- Aldridge J.
- Aldridge N.
- Alegria A.
- Alexander A.
- Alexander J.
- Alexander P.D.G.
- Alford C.
- Alghazawi L.
- Ali A.
- Ali A.
- Ali F.R.
- Ali H.
- Ali J.
- Ali M.
- Ali M.
- Ali N.
- Ali O.
- Ali S.
- Ali S.
- Ali S.
- Alina A.
- Aliyuda F.
- Alizadeh K.
- Alkhusheh M.
- Allameddine A.
- Allan F.
- Allan R.
- Allanson A.
- Allcock R.
- Allen B.
- Allen E.
- Allen J.
- Allen K.
- Allen L.
- Allen L.
- Allen P.
- Allen R.
- Allen S.
- Allen S.
- Allen S.
- Allison K.
- Allman B.
- Allsop L.
- Alomari L.
- Alshaer I.
- Altaf S.
- Alvarez M.
- Alyas B.
- Alzetani M.
- Amamou S.
- Amar N.
- Ambalavanan S.
- Ambler S.-J.
- Ambrogetti R.
- Ambrose C.
- Ameen A.
- Amenyah K.
- Amezaga M.R.
- Amin A.
- Amin A.
- Amin K.
- Amin S.
- Amin T.
- Amjad A.
- Amjad N.
- Ammoun M.
- Amosun V.
- Amsha K.
- Amy P.
- Anand A.
- Anand R.
- Anandappa S.
- Anderson J.
- Anderson K.
- Anderson L.
- Anderson M.
- Anderson N.
- Anderson R.
- Anderson R.
- Anderson W.
- Andreou P.
- Andrews A.
- Andrews A.
- Andrews J.
- Andrews S.
- Andrikopoulos G.
- Aneke K.
- Ang A.
- Ang W.W.
- Angel T.
- Angela A.
- Angelini P.
- Anguvaa L.
- Anichtchik O.
- Anim-Somuah M.
- Aniruddhan K.
- Annett J.
- Anstey P.J.
- Anstey R.
- Anthony A.
- Anthony-Pillai A.
- Antill P.
- Antonina Z.
- Anu V.
- Anwar M.
- Apostolides G.
- Apostolopoulos A.
- Appleby S.
- Appleyard D.
- Aquino M.F.
- Araba B.
- Aransiola S.
- Araujo M.
- Arbon E.
- Archer A.
- Archer D.
- Archer S.
- Ardley C.
- Arias A.-M.
- Arimoto R.
- Arkley C.
- Armah C.
- Armata I.
- Armitage A.
- Armstrong C.
- Armstrong M.
- Armstrong S.
- Armstrong-Fisher S.
- Armtrong P.
- Arndt H.
- Arnison-Newgass C.
- Arnold D.
- Arnold R.
- Arnott S.
- Arora D.
- Arora K.
- Arora P.
- Arora R.
- Arroyo A.
- Arter A.
- Arya A.
- Arya R.
- Asandei D.
- Asghar A.
- Ashbrook-Raby C.
- Ashby G.
- Ashby H.
- Ashcroft J.
- Ashcroft J.
- Ashcroft S.
- Asher D.
- Ashfaq A.
- Ashford B.
- Ashgar S.
- Ashish A.
- Ashman-Flavell S.
- Ashok S.
- Ashour A.-E.-A.
- Ashraf M.Z.
- Ashraf S.
- Ashraq M.B.
- Ashton D.
- Ashton S.
- Ashworth A.
- Ashworth R.
- Aslam A.
- Asogan H.
- Asquith A.
- Asrar A.
- Assaf O.
- Astin-Chamberlain R.
- Athay-Hunt R.
- Athorne D.
- Atkins B.
- Atkins C.
- Atkins S.
- Atkinson J.
- Atkinson V.
- Atraskiewicz B.
- Atterbury C.
- Attia A.A.
- Atugonza R.
- Aubrey P.
- Aujayeb A.
- Aung A.C.T.
- Aung H.
- Aung K.T.
- Aung N.
- Aung Y.
- Aung Z.M.
- Austin E.
- Austin K.
- Auwal A.
- Avery M.
- Avis J.
- Aviss G.
- Avram C.
- Avram P.
- Awadzi G.
- Awan A.
- Aya A.
- Ayaz E.
- Ayers A.
- Azam J.
- Azharuddin M.
- Aziz G.
- Aziz N.
- Azkoul A.
- Azman Shah A.
- Azzopardi G.
- Azzoug H.
- Babatunde F.
- Babi M.
- Babiker B.
- Babington G.
- Babirecki M.
- Babores M.
- Babs-Osibodu A.O.
- Bacciarelli S.
- Bachar R.
- Bacon G.
- Bacon J.
- Badal B.
- Badhan G.R.
- Badhrinarayanan S.
- Bae J.P.
- Bafekr Mishamandani S.
- Baggaley A.
- Baggott A.
- Bagley G.
- Bagmane D.
- Bagshaw L.
- Bahadori K.
- Bailey J.
- Bailey K.
- Bailey L.
- Bailey L.
- Bailey M.
- Bailey P.
- Bailey S.
- Bailey S.
- Baillie H.
- Baillie J.K.
- Bain J.
- Baines S.
- Bains V.
- Baird A.
- Baird D.
- Baird S.
- Baird T.
- Baird Y.
- Bajandouh A.
- Baker C.
- Baker E.
- Baker E.
- Baker J.
- Baker J.
- Baker K.
- Baker R.
- Baker T.-A.
- Baker V.
- Baker-Moffatt M.
- Bakere H.
- Bakerly N.
- Bakhtiar N.
- Bakoulas P.
- Balaam J.
- Balachandran N.
- Balan A.
- Balaskas T.
- Balasubramaniam M.
- Balcombe A.
- Baldwin A.
- Baldwin A.
- Baldwin C.
- Baldwin D.
- Baldwin-Jones R.
- Balfour J.
- Bali G.
- Balkee S.
- Ball C.
- Ballard K.
- Ballinger A.
- Balluz I.
- Balmforth C.
- Balogh E.
- Baluwala A.
- Bambridge G.
- Bamford A.
- Bamford A.
- Bamford P.
- Bamgboye A.
- Bancroft E.
- Bancroft H.
- Bancroft T.
- Banda J.
- Bandaru K.
- Bandi S.
- Bandla N.
- Bandyopadhyam S.
- Banerjee A.
- Banerjee M.
- Banerjee R.
- Banks H.
- Banks L.
- Banks L.
- Banks P.
- Bannister O.
- Bansal B.
- Banthorpe R.
- Banton L.
- Baptist M.
- Baqai T.
- Baral A.M.
- Baramova D.
- Barber A.
- Barber R.
- Barbon E.
- Barbosa M.
- Barbosa M.
- Barbour J.
- Barclay A.
- Barclay C.
- Bardsley G.
- Bareford S.
- Bari S.
- Barker A.
- Barker D.
- Barker H.
- Barker J.
- Barker L.
- Barker O.
- Barker-Williams K.
- Barkha S.
- Barla J.
- Barlow G.
- Barlow R.
- Barlow V.
- Barnacle J.
- Barnard A.
- Barnes D.
- Barnes N.
- Barnes T.
- Barnetson C.
- Barnett A.
- Barnett M.
- Barnett-Vanes A.
- Barnsley W.
- Barr A.
- Barr D.
- Barratt S.
- Barrera M.
- Barrett A.
- Barrett F.
- Barrett J.
- Barry J.
- Bartholomew J.
- Bartlett C.
- Bartlett G.
- Barton G.
- Barton J.
- Barton L.
- Barton R.
- Baruah R.
- Baryschpolec S.
- Bashyal A.
- Basker B.
- Basoglu A.
- Bass G.
- Bassett G.
- Bassett J.
- Bassford C.
- Bassi P.
- Bassis B.
- Bassoy B.
- Bastion V.
- Basumatary A.
- Bate T.
- Bateman H.J.
- Bateman I.
- Bateman K.
- Bateman V.
- Bates E.
- Bates H.
- Bates M.
- Bates S.
- Batham S.
- Batista A.
- Batla A.
- Batra D.
- Batty D.
- Batty H.
- Batty T.
- Baughan P.
- Baum M.
- Bautista C.
- Bawa F.
- Bawani F.S.
- Bax S.
- Baxter L.
- Baxter M.
- Baxter N.
- Baxter Z.
- Bayes H.
- Baylem C.
- Bayliss L.
- Bays E.
- Bazari F.
- Bazaz R.
- Bazli A.
- Beacham L.
- Beadles W.
- Beak P.
- Beale A.
- Beard K.
- Bearpark J.
- Beaumont K.
- Beaumont-Jewell D.
- Beaver T.
- Beavis S.
- Beazley C.
- Beck S.
- Beckett V.
- Beckitt R.
- Beddall H.
- Beddows S.
- Beeby D.
- Beech G.
- Beecroft M.
- Beer S.
- Beety J.
- Bega G.
- Begg A.
- Begg S.
- Beghini S.
- Begum A.
- Begum S.
- Begum S.
- Behan T.
- Beharry J.
- Behrouzi R.
- Beishon J.
- Beith C.
- Belcher J.
- Belfield H.
- Belfield K.
- Belgaumkar A.
- Bell D.
- Bell G.
- Bell G.
- Bell G.
- Bell J.
- Bell J.L.
- Bell L.
- Bell L.
- Bell N.
- Bell P.
- Bell S.
- Bellamu J.
- Bellamy M.
- Bellini A.
- Bellis A.
- Bellis F.
- Bendall L.
- Benesh N.
- Benetti N.
- Benham L.
- Benison-Horner G.
- Bennett A.
- Bennett A.
- Bennett C.
- Bennett C.
- Bennett G.
- Bennett I.
- Bennett K.
- Bennett L.
- Bennett S.
- Bennion K.
- Benson V.
- Benstead J.
- Bentley A.
- Bentley D.
- Bentley J.
- Benton I.
- Beranova E.
- Beresford M.
- Bergin C.
- Bergstrom M.
- Bernatoniene J.
- Berriman T.
- Berry Z.
- Berwick M.
- Best K.
- Bester A.-M.
- Beuvink Y.
- Bevan E.
- Bevins S.
- Bewick T.
- Bexley A.
- Beyatli S.
- Beynon F.
- Bhadi A.
- Bhagani S.
- Bhakta S.
- Bhalla R.
- Bhandal K.
- Bhandal K.
- Bhandari A.
- Bhandari S.
- Bhanot A.
- Bhanot R.
- Bhaskara S.
- Bhat P.
- Bhatia N.
- Bhatnagar R.
- Bhatt K.
- Bhayani J.
- Bhojwani D.
- Bhuiyan S.
- Bibby A.
- Bibi F.
- Bibi N.
- Bibi S.
- Bicanic T.
- Bidgood S.
- Bigg J.
- Biggs S.
- Biju A.
- Bikov A.
- Billingham S.
- Billings J.
- Bilton C.
- Binas T.
- Binney M.
- Binns A.
- BinRofaie M.
- Bintcliffe O.
- Birch C.
- Birch J.
- Birch L.
- Birchall J.
- Birchall K.
- Bird S.
- Bird S.
- Biring C.
- Birt M.
- Bisa R.
- Bishop K.
- Bishop L.
- Bishop L.
- Bisnauthsing K.
- Biswas N.
- Biuk S.
- Blachford K.
- Black E.
- Black H.
- Black K.
- Black M.
- Black P.
- Blackgrove H.
- Blackledge B.
- Blackler J.
- Blackley S.
- Blackman H.
- Blackmore S.
- Blackstock C.
- Blackwood L.
- Blakemore F.
- Blamey H.
- Bland A.
- Blane S.
- Blankley S.
- Blanton M.
- Blaxill P.
- Blaxland J.
- Blaylock K.
- Blazeby J.
- Blears C.
- Blencowe N.
- Blofield D.
- Bloom B.
- Bloomfield J.
- Bloss A.
- Bloxham H.
- Blundell L.
- Blunsum A.
- Blunt M.
- Blyth I.
- Blyth K.
- Blythe A.
- Blythe K.
- Boampoaa M.
- Bobie B.
- Bobruk K.
- Bodalia P.
- Bodasing N.
- Bodenham T.
- Bodh S.
- Boehmer G.
- Boffito M.
- Bohmova K.
- Bokhandi S.
- Bokhar M.
- Bokhari S.
- Bokhari S.
- Bokhari S.O.
- Boles A.
- Bollington S.
- Bolton S.
- Bomken C.
- Bond C.
- Bond H.
- Bond H.
- Bond S.
- Bond T.
- Bone A.
- Boniface G.
- Bonnert W.
- Bonney L.
- Boorman L.
- Booth C.
- Borbone J.
- Borhani C.
- Borman N.
- Borrell R.
- Boshir M.
- Bottrill F.
- Bough L.
- Boughton H.
- Boult Z.
- Bourke M.
- Bourke S.
- Bourne M.
- Bousfield R.
- Boustred L.
- Bowen D.
- Bowen K.
- Bowes A.
- Bowes A.
- Bowker P.
- Bowman L.
- Bowman S.
- Bowmer R.
- Bowring A.
- Bowyer G.
- Bowyer H.
- Boyd C.
- Boyd J.
- Boyd L.
- Boyd M.
- Boyle N.
- Boyle P.
- Boyle R.
- Boyles L.
- Bozdag O.
- Brace L.
- Brack D.
- Brackstone C.
- Bradburn R.
- Bradder J.
- Bradley B.
- Bradley C.J.
- Bradley P.
- Bradley P.
- Bradley P.
- Bradley-Potts J.
- Bradshaw L.
- Bradshaw S.
- Bradshaw Z.
- Brady R.
- Brady S.
- Braganza D.
- Brailsford S.
- Braithwaite J.
- Branch M.
- Brankin-Frisby T.
- Brannigan J.
- Brassington L.
- Brattan S.
- Bray F.
- Bray N.
- Brazier A.
- Brazil M.
- Brear L.
- Brear T.
- Brearey S.
- Bremner L.
- Brend M.
- Bretland G.
- Brewer C.
- Bridge H.
- Bridgwood G.
- Briggs H.
- Briggs M.
- Brigham S.
- Bright J.
- Brightling C.
- Brimfield L.
- Brinkworth E.
- Brittain-Long R.
- Britten V.
- Brittin T.
- Broad L.
- Broad S.
- Broadhurst R.
- Broadley A.
- Broadway M.
- Brockelsby C.
- Brocken M.
- Brockley T.
- Broderick A.
- Brodsky M.
- Brogan F.
- Broggio D.
- Brohan L.
- Brokke F.
- Brolly J.
- Bromley D.
- Brooke-Ball H.
- Brooker V.
- Brookes C.
- Brookes M.
- Brooks A.
- Brooks K.
- Brooks N.
- Brooks P.
- Brooks R.
- Brooks S.
- Broomhead N.
- Broughton C.
- Broughton N.
- Brouns M.
- Browett M.
- Brown A.
- Brown A.
- Brown C.
- Brown C.
- Brown C.
- Brown E.
- Brown E.
- Brown H.
- Brown J.
- Brown L.
- Brown N.
- Brown P.
- Brown R.
- Brown R.
- Brown R.
- Brown S.
- Brown T.
- Brown W.
- Browne B.
- Browne C.
- Browne D.
- Browne M.
- Brownlee S.
- Brraka A.
- Bruce D.
- Bruce J.
- Bruce M.
- Brudlo W.
- Brunskill N.
- Brunton A.
- Brunton M.
- Bryan M.
- Bryant M.
- Buazon A.
- Buch M.
- Buchan J.
- Buchan R.
- Buchanan A.
- Buchanan R.
- Buche D.
- Buck A.
- Buckland M.
- Buckley L.
- Buckley P.
- Buckley S.
- Buckman C.
- Buckmire K.
- Bugg G.
- Bujazia R.
- Bukhari M.
- Bukhari S.
- Bulbulia R.
- Bull A.
- Bull D.
- Bull R.
- Bull T.
- Bulteel N.
- Bumunarachchi K.
- Bungue-Tuble R.
- Burchett C.
- Burda D.
- Burden C.
- Burden T.G.
- Burgess M.
- Burgess P.
- Burgess R.
- Burgess S.
- Burgett P.
- Burman A.
- Burnard S.
- Burnett C.
- Burnett J.
- Burns A.
- Burns A.
- Burns C.
- Burns J.
- Burns K.
- Burns S.
- Burns S.
- Burrage D.
- Burrage S.
- Burrows K.
- Burston C.
- Burton B.
- Burton F.
- Burton M.
- Busby A.
- Butcher D.
- Butler A.
- Butler J.
- Butler J.
- Butler J.
- Butler L.
- Butler P.
- Butler S.
- Butt A.-T.
- Butt M.M.
- Butt S.
- Butterworth C.
- Butterworth-Cowin N.
- Buttery R.
- Buttle T.
- Button H.
- Buttress D.
- Byrne J.
- Byrne W.
- Byrne-Watts V.
- Byworth E.
- Cabandugama A.
- Cade R.
- Cadwgan A.
- Cairney D.
- Calderwood J.
- Caldow D.
- Caldwell M.
- Calisti G.
- Callaghan D.
- Callaghan J.
- Callens C.
- Callum D.
- Calver C.
- Cambell-Kelly M.
- Camburn T.
- Cameron D.R.
- Cameron E.
- Cameron F.
- Cameron S.
- Cameron S.
- Camm C.
- Cammack R.F.D.
- Campbell Hewson Q.
- Campbell A.
- Campbell A.
- Campbell B.
- Campbell B.
- Campbell D.
- Campbell H.
- Campbell H.
- Campbell J.
- Campbell M.
- Campbell R.
- Campbell W.
- Camsooksai J.
- Canabarro A.
- Canclini L.
- Candido S.M.
- Candlish J.
- Caneja C.
- Cann J.
- Cannan R.
- Cannon E.
- Cannon M.
- Cannon P.
- Cannons V.
- Cantliff J.
- Caplin B.
- Capocci S.
- Caponi N.
- Capp A.
- Capps-Jenner A.
- Capstick T.
- Carboo I.
- Cardenas N.
- Cardwell M.
- Carey R.
- Carley S.
- Carlin T.
- Carlton A.
- Carmichael S.
- Carnahan M.
- Carnegie R.
- Caroline C.
- Carpenter E.
- Carpenter J.
- Carr D.
- Carr S.
- Carrasco A.
- Carrington S.
- Carrington Z.
- Carroll P.
- Carron C.
- Carstairs A.
- Carter J.
- Carter M.
- Carter M.
- Carter P.
- Carter P.
- Carter S.
- Carter-Graham S.
- Cartwright D.
- Cartwright J.-A.
- Carty C.
- Carty S.
- Carungcong J.
- Carveth-Marshall C.
- Casey S.
- Cassells A.
- Cassimon B.
- Castiello T.
- Castle G.
- Castles B.
- Caswell M.
- Catana A.M.
- Cate H.
- Cathcart S.
- Cathie K.
- Catley C.
- Catlow L.
- Caudwell M.
- Caulfield J.
- Cavazza A.
- Cave L.
- Cavinato S.
- Cawa F.
- Cawley K.
- Caws C.
- Cendl H.
- Century H.
- Cernova J.
- Cesay M.
- Cetti E.
- Chabane S.
- Chablani M.
- Chabo C.
- Chadwick D.
- Chadwick J.
- Chadwick R.
- Chakkarapani E.
- Chakraborty A.
- Chakraborty M.
- Chakravorty M.
- Chalmers J.
- Chalmers R.
- Chamberlain G.
- Chamberlain S.
- Chambers E.
- Chambers J.
- Chambers L.
- Chambers N.
- Chan A.
- Chan C.
- Chan C.
- Chan E.
- Chan K.
- Chan K.
- Chan P.
- Chan R.P.-C.
- Chan X.H.
- Chandler C.
- Chandler H.
- Chandler K.J.
- Chandler S.
- Chandler Z.
- Chandler-Vizard V.
- Chandra S.
- Chandran N.
- Chandrasekaran B.
- Chang C.
- Chang Y.
- Chaplin J.
- Chapman G.
- Chapman J.
- Chapman K.
- Chapman L.
- Chapman L.
- Chapman P.
- Chapman T.
- Chappell L.
- Chapple L.
- Charalambou A.
- Charles B.
- Charlton D.
- Charlton S.
- Chatar K.
- Chatha C.
- Chaube R.
- Chaudhary M.Y.
- Chaudhry I.
- Chaudhuri N.
- Chaudhury M.
- Chauhan A.
- Chauhan R.S.
- Chauhan V.
- Chavasse N.
- Chaven I.
- Chavez R.
- Chawla V.
- Cheadle M.
- Cheater L.
- Cheaveau J.
- Cheeld C.
- Cheeseman M.
- Chen F.
- Chen H.M.
- Chen T.
- Cheng L.Y.
- Cheng Z.
- Chenoweth H.
- Cheong C.H.
- Cherian S.
- Cherif S.
- Cherrie M.
- Cheshire H.
- Chesterson B.
- Cheung B.
- Cheung C.K.
- Cheung E.
- Cheung M.
- Cheyne C.
- Chhabra S.
- Chia W.L.
- Chiang E.
- Chiapparino A.
- Chicano R.
- Chikwanha Z.A.
- Chilcott S.
- Chimbo P.
- Chin K.
- Chin W.J.
- Chineka R.
- Chingale A.
- Chinn K.
- Chiroma V.
- Chisem H.
- Chisenga C.
- Chisnall B.
- Chiswick C.
- Chita S.
- Chitalia N.
- Chiu M.
- Chivima B.
- Chmiel C.
- Choi S.
- Choon Kon Yune W.
- Choudhary V.
- Choudhury S.
- Chow B.-L.
- Chowdhury F.
- Chowdhury M.
- Chowdhury S.
- Christenssen V.
- Christian P.
- Christides A.
- Christie F.
- Christmas D.
- Christopherson T.
- Christy M.
- Chrysostomou P.
- Chua Y.
- Chucha S.
- Chudgar D.
- Chudleigh R.
- Chukkambotla S.
- Chukwu M.E.
- Chukwulobelu I.
- Chung C.Y.
- Church B.
- Church E.
- Church S.R.
- Churchill D.
- Cianci N.
- Ciccone N.
- Cicconi P.
- Cinardo P.
- Cipinova Z.
- Cipriano B.
- Clamp S.
- Clapham M.
- Clare E.
- Clare S.
- Clark A.
- Clark C.
- Clark D.
- Clark F.
- Clark G.
- Clark J.
- Clark K.
- Clark K.
- Clark L.
- Clark L.
- Clark M.
- Clark P.
- Clark R.
- Clark T.
- Clark W.
- Clark Z.
- Clarke A.
- Clarke H.
- Clarke M.
- Clarke P.
- Clarke R.
- Clarke R.
- Clarke S.
- Clarke S.
- Clarke S.
- Clarke T.
- Clarkson A.
- Claxton A.
- Clay K.
- Clayton E.
- Clayton O.
- Clayton-Smith J.
- Cleaver C.
- Clemente de la Torre C.
- Clements J.
- Clements S.
- Clemons F.
- Clifford L.
- Clifford L.
- Clifford R.
- Clifford S.
- Clive A.
- Clouston J.
- Clueit S.
- Clyne A.
- Coakley M.
- Coakley P.G.L.
- Coates T.
- Cobain K.
- Cochrane A.
- Cochrane P.
- Cockerell M.
- Cockerill H.
- Cocks S.
- Codling R.
- Coe A.
- Coetzee S.
- Coey D.
- Cohen D.
- Cohen J.
- Cohen O.
- Cohn M.
- Coke L.
- Coker O.
- Colbeck N.
- Colbert R.
- Cole C.
- Cole E.
- Cole J.
- Cole J.
- Cole J.
- Cole R.
- Cole S.
- Coleman G.
- Coleman M.
- Coles H.
- Coles R.
- Colin M.
- Colino-Acevedo A.
- Colley J.
- Collier D.
- Collier H.
- Collini P.
- Collins E.
- Collins J.
- Collins J.
- Collins N.
- Collins S.
- Collins V.
- Collinson A.
- Collinson B.
- Collinson J.
- Collis M.
- Colmar M.
- Colton H.E.
- Colton J.
- Colville K.
- Colvin C.
- Colwell R.
- Combes E.
- Comer D.
- Comerford A.
- Comery M.
- Concannon D.
- Condliffe R.
- Connell L.
- Connell N.
- Connelly K.
- Connolly G.
- Connolly M.
- Connor E.
- Conran S.
- Conroy A.
- Conteh V.
- Convery R.
- Conway C.
- Conway F.
- Conway G.
- Conway R.
- Conyngham J.-A.
- Cook C.
- Cook E.
- Cook G.
- Cook H.
- Cook J.
- Cooke D.
- Cooke G.
- Cooke K.
- Cooke S.
- Cooke T.
- Cooper A.
- Cooper A.
- Cooper C.
- Cooper D.
- Cooper H.
- Cooper J.
- Cooper J.
- Cooper J.
- Cooper L.
- Cooper L.
- Cooper N.
- Cooper R.
- Cooperwaite E.
- Cope T.
- Corbet S.
- Corbett C.
- Corcoran J.
- Cordell C.
- Cordle J.
- Corfield A.
- Corless J.
- Corlett A.
- Cornwell J.
- Cornwell M.
- Corogeanu D.
- Corredera M.
- Corrigan R.
- Corry C.
- Corser R.
- Cosgrove D.
- Cosier T.
- Costa P.
- Coston C.
- Cotgrove S.
- Coton Z.
- Cottam L.-J.
- Cotter R.
- Cotterill D.
- Cotton A.
- Cotton C.
- Cotton K.
- Coull A.
- Coulson J.
- Counsell D.
- Counter D.
- Coupland C.
- Courtney E.
- Courtney J.
- Cousins R.
- Cowan A.
- Cowan E.
- Cowburn R.
- Cowell R.
- Cowen L.
- Cowman S.
- Cowton A.
- Cox D.A.
- Cox E.
- Cox G.
- Cox K.
- Cox M.
- Coy K.
- Craig B.
- Craig V.
- Craighead F.
- Cramp M.
- Crane B.
- Crause J.
- Crawford A.
- Crawford A.
- Crawford E.
- Crawford I.
- Crawforth R.
- Crawshaw S.
- Creagh-Brown B.
- Creamer A.
- Creighton R.
- Cremona J.
- Cremona S.
- Cresswell J.
- Cribb M.
- Crichton C.
- Crilly D.
- Crisp L.
- Crisp N.
- Crocombe D.
- Croft M.
- Cron I.
- Crook D.
- Crooks J.
- Croot H.
- Crosby H.
- Cross S.
- Cross T.
- Crothers A.
- Crotty S.
- Crouch S.
- Crow M.
- Crowder A.
- Crowley K.
- Crowley T.
- Croysdill R.
- Cruickshank C.
- Cruickshank C.
- Cruickshank I.
- Cruise J.
- Crumley H.
- Cruz Cervera T.
- Cruz C.
- Cryans D.
- Cui G.
- Cui H.
- Cullen D.
- Cullen L.
- Cummings-Fosong G.
- Cundall M.
- Cunliffe V.
- Cunningham L.
- Cunningham N.
- Cunningham N.
- Cupitt J.
- Curgenven H.
- Curley D.
- Curnow G.
- Curran D.
- Curran S.
- Currie C.
- Currie J.
- Currie S.
- Curtis A.
- Curtis B.
- Curtis J.
- Curtis K.
- Curtis O.
- Curtis T.
- Cuthbertson R.
- Cutler S.
- Czekaj M.
- Czylok P.
- D'Costa P.
- da Rocha J.
- Dagens A.
- Daggett H.
- Daggett P.
- Daglish J.
- Dahiya S.
- Dakers-Black H.
- Dale A.
- Dale K.
- Dale M.
- Dale S.
- Dales J.
- Dalgleish H.
- Dallas N.
- Dallow H.
- Dalton D.
- Daly Z.
- Danga A.
- Daniel A.
- Daniel P.
- Daniels A.
- Dann A.
- Danso-Bamfo S.
- Daoud N.
- Darbyshire A.
- Darbyshire J.
- Dargan P.
- Dark P.
- Darling T.
- Darlington K.
- Darton T.
- Darylile G.
- Das M.
- Das S.
- Daschel M.
- Dasgin J.
- Datta D.
- Daunt A.
- Davenport E.
- Davey M.
- Davey M.
- Davey M.
- Davey M.
- David A.
- David M.
- Davidson A.
- Davidson L.
- Davidson N.
- Davidson R.
- Davies A.
- Davies A.
- Davies A.
- Davies A.
- Davies A.
- Davies C.
- Davies C.
- Davies C.
- Davies D.
- Davies E.
- Davies F.
- Davies H.
- Davies J.
- Davies J.
- Davies J.
- Davies J.
- Davies K.
- Davies K.
- Davies K.
- Davies L.
- Davies M.
- Davies M.
- Davies M.
- Davies N.
- Davies O.
- Davies P.
- Davies R.
- Davies R.
- Davies R.
- Davies S.
- Davies S.
- Davis A.
- Davis G.
- Davis I.
- Davis J.-A.
- Davis K.
- Davis P.
- Davison A.
- Davison S.
- Davy M.
- Dawe C.
- Dawe H.
- Dawkins M.
- Dawson D.
- Dawson E.
- Dawson J.
- Dawson S.
- Dawson T.
- Daxter A.
- Day A.
- Day H.
- Day J.
- Day J.
- Day L.
- de Fonseka D.
- Dey V.
- Vara S.
- Vardigans K.
- Vardy S.J.
- Varghese A.
- Varghese M.
- Varney W.
- Varnier G.
- Vasadi V.
- Vass O.
- Vasu V.
- Vasudevan V.
- Vatish M.
- Vayalaman H.
- Vaz C.
- Veale N.
- Veerasamy S.
- Velan B.
- Velankar S.
- Velauthar L.
- Veli N.
- Vella N.
- Velusamy A.
- Venables I.
- Venditti M.
- Veniard D.
- Venkataramakrishnan R.
- Venn R.
- Venn R.
- Ventilacion L.
- Vere J.
- Veres M.
- Vergnano S.
- Verling W.
- Verma A.
- Vernall R.
- Vernon B.
- Vertue M.
- Verula J.
- Vethanayagam N.
- Veys L.
- Vickers C.
- Victor S.
- Vidler J.
- Vietri W.
- Vijayakumar B.
- Vijayaraghavan Nalini V.W.
- Vilcinskaite B.
- Vilimiene N.
- Vimalanathan S.
- Vinall L.
- Vinay S.
- Vinayakarao L.
- Vincent R.
- Vincent R.
- Virdee P.
- Virgilio E.
- Virk A.M.
- Visentin E.
- Visuvanathan J.
- Vithian K.
- Vittoria S.
- Vlad E.
- Vlies B.
- Vuylsteke A.
- Vyras E.
- Wach R.
- Wadams B.
- Wadd S.
- Waddington N.
- Wadsworth K.
- Wafa S.E.
- Wagstaff D.
- Wagstaff L.
- Wahab D.
- Wahbi Z.
- Waheed Adigun A.
- Waidyanatha S.
- Wake R.
- Wakefield A.
- Wakeford W.
- Wakelin M.
- Wakinshaw F.
- Walden A.
- Walden J.
- Walding L.
- Waldron A.
- Walker G.
- Walker H.
- Walker I.
- Walker J.
- Walker K.
- Walker K.
- Walker L.
- Walker M.T.
- Walker O.
- Walker R.
- Walker R.
- Walker S.
- Wallbank D.
- Wallbutton R.
- Wallen J.
- Wallendszus K.
- Waller A.
- Waller F.
- Waller R.
- Wallis G.
- Wallis G.
- Wallis L.
- Walsh D.
- Walsh E.
- Walsh L.
- Walstow D.
- Walter D.
- Walters A.
- Walters H.
- Walters J.
- Walters J.
- Walton E.
- Walton L.
- Walton O.
- Walton S.
- Walton S.
- Wan M.
- Wan T.
- Wands M.
- Wane R.
- Wang F.
- Wang N.
- Wang R.
- Warbrick D.
- Warburton S.
- Ward D.
- Ward E.
- Ward J.
- Ward K.
- Ward L.
- Ward N.
- Ward R.
- Ward R.
- Ward T.
- Ward T.
- Warden S.A.
- Wardle A.
- Wardle K.
- Wardle S.
- Wardy H.
- Waring S.
- Warmington J.
- Warner B.
- Warner C.
- Warnock L.
- Warran S.
- Warren J.
- Warren L.
- Warren Y.
- Warren-Miell H.
- Warwick G.
- Washington C.
- Wassall H.
- Watchorn H.J.
- Waterfall H.
- Waters A.
- Waters D.
- Waterstone M.
- Watkins C.
- Watkins C.
- Watkins E.
- Watkins K.
- Watkins L.
- Watkins N.
- Watson A.
- Watson A.J.
- Watson E.
- Watson E.
- Watson P.
- Watson R.
- Watson R.
- Watson S.
- Watters M.
- Watterson D.
- Watts D.
- Watts J.
- Watts M.
- Waugh V.
- Wayman E.
- Wazir A.
- Weatherhead M.
- Weatherly N.
- Weaver P.
- Webb H.
- Webb K.
- Webb K.
- Webb S.
- Websdale C.
- Webster D.
- Webster I.
- Webster T.
- Wedgeworth K.
- Wee L.
- Weerakoon R.
- Weerasinghe T.
- Weeratunga J.
- Weetman M.
- Wei S.
- Weichert I.
- Welch H.
- Welch J.
- Welch L.
- Welch S.
- Weller S.
- Wellings L.
- Wells B.
- Wellstead S.
- Welsh B.
- Welsh R.
- Welters I.
- Welton R.
- Wentworth L.
- Wesseldine K.
- Wesson J.
- Wesson J.
- West A.
- West M.
- West R.
- West R.
- West S.
- Western L.
- Westhead R.
- Weston H.
- Westwood A.
- Wetherill B.
- Wheaver S.
- Wheeler H.
- Whelan B.
- Whelband M.
- Whileman A.
- Whitcher A.
- White A.
- White A.
- White B.
- White C.
- White D.
- White E.
- White J.
- White J.
- White K.
- White M.
- White N.
- White S.
- White S.
- White S.
- White T.
- Whitehead C.
- Whitehouse A.
- Whitehouse C.
- Whitehouse T.
- Whiteley J.
- Whiteley S.
- Whiteside V.
- Whitley D.
- Whitley K.
- Whitlingum G.
- Whitmore D.
- Whittaker E.
- Whittam L.
- Whittingham Hirst A.
- Whittington A.
- Whittle H.
- Whittle R.
- Whyte S.
- Wiafe E.
- Wiblin L.
- Widdrington J.
- Wieboldt J.
- Wieringa H.
- Wiesender C.
- Wiffen L.
- Wight A.
- Wignall C.
- Wilcock D.
- Wilcock E.
- Wilcox L.
- Wild L.
- Wild S.
- Wilde M.
- Wilding P.
- Wildman R.
- Wildsmith T.
- Wileman J.
- Wiles D.
- Wiles J.
- Wiles K.
- Wilhelmsen E.
- Wiliams T.
- Wilkes C.
- Wilkie J.
- Wilkin D.
- Wilkins H.
- Wilkins J.
- Wilkins S.
- Wilkinson H.
- Wilkinson H.
- Wilkinson I.
- Wilkinson L.
- Wilkinson M.
- Wilkinson N.
- Wilkinson S.
- Wilkinson S.
- Wilkinson T.
- Willetts S.
- Williams A.
- Williams A.
- Williams A.
- Williams A.
- Williams A.
- Williams C.
- Williams C.
- Williams C.V.
- Williams D.
- Williams G.
- Williams G.
- Williams G.
- Williams H.
- Williams J.
- Williams J.
- Williams J.
- Williams J.
- Williams J.
- Williams K.
- Williams K.
- Williams M.
- Williams M.
- Williams P.
- Williams P.
- Williams R.
- Williams R.
- Williams S.
- Williams S.
- Williams S.
- Williams T.
- Williamson A.
- Williamson C.
- Williamson C.
- Williamson D.
- Williamson H.
- Williamson J.D.
- Williamson R.
- Willian B.
- Willis E.
- Willis E.
- Willis H.
- Willis H.
- Willis J.
- Willmott L.
- Wills L.
- Willsher L.
- Willshire C.
- Willson F.
- Wilson A.
- Wilson A.
- Wilson A.
- Wilson B.
- Wilson C.
- Wilson E.
- Wilson J.
- Wilson K.
- Wilson K.
- Wilson L.
- Wilson M.
- Wilson M.
- Wilson T.
- Wiltsher E.
- Win M.
- Win T.
- Win W.Y.W.
- Winckworth L.
- Winder L.
- Winder P.
- Windrum P.
- Winham-Whyte K.
- Winmill H.
- Winn S.
- Winpenny C.
- Winslow H.
- Winter H.
- Winter J.
- Winter P.
- Winter-Goodwin B.
- Wisdom S.
- Wise M.
- Wiselka M.
- Wiseman R.
- Wiseman S.
- Wishart S.
- Wissett H.
- Witele E.
- Withers N.
- Wittes J.
- Wixted D.
- Wodehouse T.
- Wolf W.
- Wolf-Roberts R.
- Wolff N.
- Wolffsohn K.
- Wolna M.
- Wolodimeroff E.
- Wolstencroft A.
- Wong A.
- Wong C.
- Wong C.-H.
- Wong E.
- Wong J.S.Y.
- Wong K.Y.
- Wong L.
- Wong M.Y.
- Wong N.
- Wong S.
- Wong Y.M.
- Wood A.
- Wood C.
- Wood C.A.
- Wood D.
- Wood F.
- Wood H.
- Wood J.
- Wood J.
- Wood J.
- Wood K.
- Wood L.
- Wood L.
- Wood M.
- Wood S.
- Wood T.
- Wood U.
- Woodall K.
- Woodfield R.
- Woodford C.
- Woodford E.
- Woodford J.
- Woodford L.
- Woodhead L.
- Woodhead T.
- Woodland P.
- Woodman M.
- Woods D.
- Woods J.
- Woods K.
- Woods S.
- Woodward Z.
- Wookey R.
- Woolcock M.
- Wooldridge G.
- Woolf R.
- Woollard C.
- Woollard C.
- Woollen L.
- Woolley E.
- Woolley J.
- Woosey D.
- Wootton D.
- Wootton J.
- Worley D.
- Worton S.
- Wraight J.
- Wray M.
- Wreford-Bush T.
- Wren J.
- Wren K.
- Wren L.
- Wrey Brown C.
- Wright C.
- Wright D.
- Wright F.
- Wright I.
- Wright L.
- Wright L.
- Wright P.
- Wright R.
- Wright R.
- Wright S.
- Wright T.
- Wroe C.
- Wroe H.
- Wu H.
- Wu P.
- Wu P.
- Wubetu J.
- Wulandari R.
- Wyatt C.
- Wyn-Griffiths F.
- Wynter I.
- Xavier B.
- Xhikola A.
- Xia Z.
- Xiao H.
- Yakubi M.
- Yan M.
- Yang F.
- Yang Y.
- Yanney M.
- Yap W.L.
- Yaqoob N.
- Yaqub N.
- Yasmin S.
- Yates B.
- Yates D.
- Yates E.
- Yates H.
- Yates J.
- Yates M.
- Yearwood Martin C.
- Yeatman A.
- Yein K.
- Yelnoorkar F.
- Yew P.
- Yip K.
- Ylquimiche Melly L.
- Ylquimiche L.
- Ynter I.
- Yong H.
- Yorke J.
- Youens J.
- Younes Ibrahim A.
- Young E.
- Young G.
- Young L.
- Young R.
- Yousafzar A.
- Youssouf S.
- Yousuf A.
- Yu C.
- Yung B.
- Yusef D.
- Yusef S.
- Yusuf I.
- Zafar A.-S.
- Zagalo S.
- Zaher S.
- Zahoor A.
- Zaki K.
- Zakir N.
- Zalewska K.
- Zamalloa A.
- Zaman M.
- Zaman R.
- Zaman S.
- Zamikula J.
- Zammit L.
- Zammit-Mangion M.
- Zarb L.
- Zebracki E.
- Zehnder D.
- Zeidan L.
- Zelman M.
- Zhao X.
- Zheng D.
- Zhu D.
- Zia M.
- Zibdeh O.
- Zill-E-Huma R.
- Zin E.T.
- Zindonda V.
- Zinkin E.
- Zinyemba V.
- Zipitis C.
- Zmierczak A.
- Zubir A.
- Zuha R.
- Zuhra N.
- Zulaikha R.
- Zulfikar S.
- Zullo C.
- Zuriaga-Alvaro A.
- Zuurbier W.
- Zyengi S.
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/05/2021
- Field of study
Background:
Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19.
Methods:
This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from across the UK. Eligible and consenting patients were randomly assigned (1:1) to receive either usual care alone (usual care group) or usual care plus high-titre convalescent plasma (convalescent plasma group). The primary outcome was 28-day mortality, analysed on an intention-to-treat basis. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.
Findings:
Between May 28, 2020, and Jan 15, 2021, 11558 (71%) of 16287 patients enrolled in RECOVERY were eligible to receive convalescent plasma and were assigned to either the convalescent plasma group or the usual care group. There was no significant difference in 28-day mortality between the two groups: 1399 (24%) of 5795 patients in the convalescent plasma group and 1408 (24%) of 5763 patients in the usual care group died within 28 days (rate ratio 1·00, 95% CI 0·93–1·07; p=0·95). The 28-day mortality rate ratio was similar in all prespecified subgroups of patients, including in those patients without detectable SARS-CoV-2 antibodies at randomisation. Allocation to convalescent plasma had no significant effect on the proportion of patients discharged from hospital within 28 days (3832 [66%] patients in the convalescent plasma group vs 3822 [66%] patients in the usual care group; rate ratio 0·99, 95% CI 0·94–1·03; p=0·57). Among those not on invasive mechanical ventilation at randomisation, there was no significant difference in the proportion of patients meeting the composite endpoint of progression to invasive mechanical ventilation or death (1568 [29%] of 5493 patients in the convalescent plasma group vs 1568 [29%] of 5448 patients in the usual care group; rate ratio 0·99, 95% CI 0·93–1·05; p=0·79).
Interpretation:
In patients hospitalised with COVID-19, high-titre convalescent plasma did not improve survival or other prespecified clinical outcomes.
Funding:
UK Research and Innovation (Medical Research Council) and National Institute of Health Research
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- Author
- Abbas M.
- Abdul Rasheed A.
- Abdul A.
- Abdul-Kadir R.
- Abdusamad K.
- Abernethy K.
- Aboelela H.
- Abouzaid M.
- Abraham M.
- Abraham T.
- Abrams J.
- Abu H.
- Abu-Arafeh A.
- Acton C.
- Adam F.
- Adam M.
- Adams C.
- Adams C.
- Adams D.
- Adams L.
- Addo A.
- Adedeji O.
- Adegoke K.
- Adewunmi E.
- Adeyemo T.
- Agbeko R.
- Aggarwal S.
- Ahmad S.
- Ahmed A.
- Ahmed I.
- Ahmed M.
- Ahmed R.
- Ahmed R.
- Ainsworth M.
- Ajmi A.
- Akili S.
- Al Aaraj A.
- Al Balushi A.
- Al-Asadi A.
- Al-Khalil M.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Sheklly B.
- Albert P.
- Alegria A.
- Alexander A.
- Alexander P.
- Alhabsha O.
- Ali M.
- Ali M.
- Aliberti E.
- Alin J.
- Aliyuda F.
- Alkhudhayri A.
- Allan N.
- Allanson A.
- Allen E.
- Allen L.
- Alshaer I.
- Altaf S.
- Amezaga M.
- Amin A.
- Amit B.
- Anand A.
- Anantapatnaikuni S.
- Anderson L.
- Anderson M.
- Anderson M.
- Anderson N.
- Anderson R.
- Andrews A.
- Ang A.
- Anguvaa L.
- Aniruddhan K.
- Antonina Z.
- Araujo M.
- Archer A.
- Archer S.
- Arimoto R.
- Arkley C.
- Armah C.
- Armistead J.
- Armstrong C.
- Arnison-Newgass C.
- Arora D.
- Arya A.
- Arya R.
- Asghar A.
- Ashbrook-Raby C.
- Asher G.
- Ashley D.
- Ashraf S.
- Ashton D.
- Ashworth R.
- Aslam A.
- Atomode A.
- Attubato E.
- Aubrey P.
- Aujayeb A.
- Aung N.
- Avery M.
- Avram C.
- Aya A.
- Ayaz E.
- Aziz G.
- Babatunde F.
- Babington G.
- Bachour M.
- Badhan G.
- Bae J.
- Bagley G.
- Bagshaw L.
- Bailey A.
- Baillie J.
- Baillie J.K.
- Baird D.
- Bajandouh A.
- Baker D.
- Baker K.
- Bakere H.
- Bakhai A.
- Balasingam P.
- Balaskas T.
- Balasubramaniam M.
- Balcombe A.
- Baldwin A.
- Baldwin-Jones R.
- Balfour J.
- Balmforth C.
- Baluwala A.
- Bamford A.
- Bancroft H.
- Banda J.
- Banks H.
- Banks P.
- Bannister O.
- Baptist M.
- Barclay C.
- Barker D.
- Barker J.
- Barker-Williams K.
- Barnacle J.
- Barnard A.
- Barnes R.
- Barnett-Vanes A.
- Barr A.
- Barr D.
- Barrera M.
- Barrett A.
- Barrow E.
- Bartholomew J.
- Bartlett G.
- Bartley S.
- Barton J.
- Barton L.
- Baruah R.
- Bashir H.
- Bashyal A.
- Basoglu A.
- Bassett J.
- Bateman K.
- Bates M.
- Batra D.
- Baxter M.
- Bazaz R.
- Beacham L.
- Beadon K.
- Beard K.
- Beaumont-Jewell D.
- Beazley C.
- Beddall H.
- Beddows S.
- Beer S.
- Beety J.
- Bega G.
- Begg S.
- Behrouzi R.
- Belcher J.
- Belfield K.
- Bell J.
- Bell N.
- Bellamy M.
- Bellamy T.
- Bendall L.
- Benetti N.
- Bennett A.
- Bennett M.
- Benson V.
- Bentley A.
- Beranova E.
- Beresford M.
- Bergin C.
- Bernatoniene J.
- Best K.
- Bhadi A.
- Bhagani S.
- Bhandal K.
- Bhandari A.
- Bhat A.
- Bhojwani D.
- Biggs S.
- Biju A.
- Bikov A.
- Birch C.
- Birchall K.
- Biswas N.
- Black P.
- Blackgrove H.
- Blackledge B.
- Blackley S.
- Blackman H.
- Blackstock C.
- Blair C.
- Blamey H.
- Blane S.
- Blazeby J.
- Blencowe N.
- Bloss A.
- Blunt T.
- Bobie B.
- Bobruk K.
- Boehmer G.
- Bohnacker N.
- Bokhari S.
- Bond H.
- Boothroyd M.
- Bostock K.
- Boumrah T.
- Bourke S.
- Bowes A.
- Bowker P.
- Bowler H.
- Bowman L.
- Bowman S.
- Bowring A.
- Boyd J.
- Boyle P.
- Bracken A.
- Bradley P.
- Bradley P.
- Bradley P.
- Bradley-Potts J.
- Brady S.
- Braithwaite M.
- Brankin-Frisby T.
- Bray F.
- Brear T.
- Brend M.
- Bretland G.
- Bridgwood G.
- Bright J.
- Broadhurst R.
- Brockelsby C.
- Brockley T.
- Brodsky M.
- Brokke F.
- Brookes M.
- Brooks S.
- Brown J.
- Brown J.
- Brown N.
- Brown R.
- Brown R.
- Brraka A.
- Bruce J.
- Bruce M.
- Brudlo W.
- Buch M.H.
- Buchan R.
- Buck A.
- Buck L.
- Buckley L.
- Bugg G.
- Bujazia R.
- Bullock E.
- Burda D.
- Burden T.
- Burgess S.
- Burman A.
- Burston C.
- Burton A.
- Butler E.
- Butler J.
- Butler P.
- Butt M.
- Button H.
- Buttress D.
- Byrne J.
- Byrne W.
- Byrne-Watts V.
- Cale E.
- Calisti G.
- Callens C.
- Cameron E.
- Cameron S.
- Camm C.
- Cammack R.
- Campbell Hewson Q.
- Campbell B.
- Campbell D.
- Campbell H.
- Campbell H.
- Campbell M.
- Campbell R.
- Cann A.
- Cannon A.
- Cantliff J.
- Caplin B.
- Capp A.
- Carey C.
- Carey R.
- Carley S.
- Carmody M.
- Carnahan M.
- Carrington Z.
- Carroll A.
- Carson R.
- Carter J.
- Carter P.
- Carty C.
- Carty L.
- Casey S.
- Cate H.
- Caws C.
- Century H.
- Chadwick J.
- Chakkarapani E.
- Chakraborty A.
- Chamberlain S.
- Chambers E.
- Chambers L.
- Chan E.
- Chan R.
- Chaplin J.
- Chapman G.
- Chapman K.
- Chapman L.
- Chapman P.
- Chappell L.
- Charles B.
- Charlton D.
- Chatar K.
- Chatterton D.
- Chaudhuri N.
- Chauhan R.
- Chawla V.
- Chen F.
- Cheng F.
- Cherrie M.
- Cheung E.
- Cheyne C.
- Chilcott S.
- Chilvers A.
- Chin K.
- Chineka R.
- Chinonso E.
- Chisnall B.
- Chiswick C.
- Chivima B.
- Chmiel C.
- Chrisopoulou A.
- Christian P.
- Christides A.
- Christmas D.
- Church E.
- Cianci N.
- Cicconi P.
- Clare E.
- Clark E.
- Clark G.
- Clark J.
- Clark L.
- Clark R.
- Clarke A.
- Clarke R.
- Clarke S.
- Clay K.
- Clayton-Smith J.
- Cleaver C.
- Clemente de la Torre C.
- Clifford S.
- Coakley M.
- Cobain K.
- Cochrane P.
- Cocks S.
- Coe A.
- Coey D.
- Cohen D.
- Cohen D.
- Coker O.
- Cole J.
- Coleman G.
- Coles H.
- Collier D.
- Collini P.
- Collins J.
- Collins V.
- Colton H.
- Condliffe R.
- Connell E.
- Connell L.
- Connelly K.
- Connolly G.
- Connor E.
- Conroy K.
- Conteh V.
- Conway R.
- Cook E.
- Cooke G.
- Cooke H.
- Cooper D.
- Cooper L.
- Cooper N.
- Cooray S.
- Corbett C.
- Corbishley A.
- Cornwell J.
- Corr A.
- Corredera M.
- Corrigan R.
- Cosier T.
- Coston C.
- Cotterill D.
- Coull A.
- Courtney E.
- Cowen L.
- Cowman S.
- Cox E.
- Coy K.
- Cradduck-Bamford A.
- Crasta S.
- Crause J.
- Crawford A.
- Crawford E.
- Crawshaw S.
- Creagh-Brown B.
- Cremona J.
- Cribb M.
- Crichton C.
- Crisp L.
- Crisp N.
- Crosby H.
- Cross T.
- Crotty S.
- Cruickshank C.
- Cruise J.
- Cryans D.
- Cui G.
- Cui H.
- Cummings-Fosong G.
- Curran S.
- Currie J.
- Currie S.
- Curtis K.
- Curtis T.
- Czylok P.
- Daglish J.
- Dalgleish H.
- Dalton M.
- Damm E.
- Darbyshire J.
- Darnell S.
- Darton T.
- Das S.
- Dasgin J.
- Daunt A.
- Dave V.
- Davey M.
- Davidson N.
- Davies B.
- Davies C.
- Davies J.
- Davies K.
- Davies N.
- Davies P.
- Davies R.
- Davis A.
- Davis J.
- Davis P.
- Dawe C.
- Dawson A.
- Day J.
- de Fonseka D.
- de Silva T.
- De Soyza A.
- De Soyza A.
- de Vos J.
- Dean K.
- Deane J.
- Dear J.
- Deelchand V.
- Deery J.
- DeMets D.
- Denis E.
- Dent M.
- Denton E.
- Denwood T.
- Dermody S.
- Desai A.
- Desai A.
- Deshpande S.
- Dey P.
- Dhaliwal K.
- Dhani S.
- Dhasmana D.J.
- Dhillon R.
- Dicks P.
- Digby J.
- Dimitri P.
- Dismore L.
- Ditchfield L.
- Dixon C.
- Dixon K.
- Dobbie L.
- Dobson C.
- Dobson L.
- Docherty M.
- Dockrell D.
- Dodds R.
- Dodds S.
- Dolan D.
- Dolman M.
- Donald L.
- Donaldson D.
- Donaldson K.
- Donlon S.
- Donohoe A.
- Donohoe G.
- Dosani M.
- Dosanjh D.
- Dowden L.
- Dowling S.
- Downey R.
- Downs L.
- Downs L.
- Dowson S.
- Drake C.
- Drewett O.
- Drogan H.
- Drummond G.
- Druryk K.
- Du Thinh A.
- Duckles-Leech H.
- Duffield E.
- Duffy H.
- Duggan A.
- Dummer S.
- Duncan C.
- Duncan F.
- Duncan G.
- Duncan R.
- Dunleavy J.
- Dunn A.
- Duran B.
- Durrans L.
- Durrington H.
- Duru I.
- Dymond H.
- D’Costa J.
- D’Mello A.
- Eades C.
- Early J.
- Eatough R.
- Eddleston M.
- Edgerley K.
- Edmond N.
- Edwards C.
- Edwards J.
- Ehiorobo L.
- Ekoi M.
- Elbeshy M.
- Elenwa U.
- Elgohary A.
- Ellis C.
- Ellwood A.
- Elokl M.
- Elsefi T.
- Elyoussfi S.
- Emberson J.R.
- Emms M.
- Emond F.
- Emonts M.
- Essa F.
- Evans B.
- Evans G.
- Evans M.
- Evans R.
- Everden C.
- Everden S.
- Evison L.
- Ezenduka C.
- Fairbairn I.
- Fairclough A.
- Falconer E.
- Faluyi D.
- Fancois V.
- Farmery T.
- Farooq H.
- Farrell B.
- Farzana S.
- Fatemi A.
- Fatemi M.
- Faust S.N.
- Faust S.N.
- Fearby S.
- Felton T.
- Fenlon K.
- Fenn A.
- Fenner I.
- Fenton C.
- Ferenando G.
- Ferguson C.
- Ferguson S.
- Ferguson S.
- Ferguson S.
- Ferguson V.
- Fernandez Lopez S.
- Ferriman E.
- Ferron S.
- Fethers N.
- Fielding J.
- Finch S.
- Fineman N.
- Finn A.
- Fiouni S.
- Fisher J.
- Fitzgerald F.
- Flaherty J.
- Flaherty J.
- Fleming L.
- Fletcher L.
- Fogarty G.
- Foot H.
- Fordham I.
- Forrest A.
- Forster E.
- Foster E.
- Foster R.
- Fowler R.
- Fowler S.
- Fox A.
- Fox C.
- Fox C.
- Fox S.
- Frake R.
- Francis S.
- Frankland H.
- Franklin J.
- Franklin S.
- Freeman H.
- Freeman N.
- Freeman N.
- Frise M.
- Froud O.
- Fullerton D.
- G N.
- Gabbitas E.
- Gabriel C.
- Gabriel Z.
- Gale C.
- Gale H.
- Gallagher B.
- Gamble L.
- Gan C.
- Garden E.
- Gardiner P.
- Gardiner S.
- Garg I.
- Garty F.
- Gaughan E.
- Gaughan E.
- Geele F.
- George B.
- George S.
- George V.
- Georgiou D.
- Gerdes L.
- Gettings S.
- Giannopoulou S.
- Gibani M.
- Gibb C.
- Gibbison B.
- Gibbons K.
- Gibson A.
- Gill L.
- Gillesen A.
- Gillian A.
- Gilliland D.
- Gillott R.
- Gilmour K.
- Gipson A.
- Glasgow S.
- Glover Bengtsson J.
- Glynn S.
- Gnanalingam C.
- Godden E.
- Godden E.
- Godson E.
- Goldacre R.
- Goodall J.
- Goodenough B.
- Goodwin E.
- Goodwin J.
- Goonasekara M.
- Gorsuch T.
- Gosai J.
- Gotham D.
- Gould N.
- Gould S.
- Gourbault L.
- Gowans S.
- Gower H.
- Graham J.
- Grahamslaw J.
- Grana G.
- Grant A.
- Grant D.
- Gray A.
- Gray G.
- Gray J.
- Gray K.
- Grayson A.
- Green A.
- Green A.
- Green C.
- Green C.A.
- Green N.
- Greene D.
- Greenhalgh A.
- Gregory K.
- Greig J.
- Gresty J.
- Grey G.
- Griffin B.
- Griffin M.
- Grobovaite E.
- Groome R.
- Grover H.
- Grubb N.
- Grundy J.
- Guerin J.
- Guerin J.
- Gureviciute A.
- Gurung Rai S.
- Gurung L.
- Hackney P.
- Hadfield D.
- Hadfield S.
- Haider N.
- Haigh K.
- Haile V.
- Hainey S.
- Hainey S.
- Hall A.
- Hall A.
- Hall C.
- Hall E.
- Hall J.
- Hallas J.
- Halls H.
- Hamdollah-Zadeh M.
- Hameed B.
- Hamid I.
- Hamilton G.
- Hamilton M.
- Hamilton S.
- Hammans B.
- Hammersley S.
- Hammond S.
- Hamoodi I.
- Hampshire K.
- Hampson L.
- Hanci O.
- Handrean S.
- Handzewniak N.
- Haney S.
- Hanison E.
- Hannington A.
- Hanrath A.
- Hanson A.
- Hanson H.
- Hanson J.
- Hanson S.
- Harden L.
- Harding Z.
- Hardman S.
- Hargreaves C.
- Harin A.
- Harman T.
- Harper C.
- Harper H.
- Harris J.
- Harris M.
- Harrison D.
- Harrison M.
- Harrison R.
- Harrison R.
- Harrison S.
- Harrod E.
- Hartrey W.
- Harvey A.
- Harvey M.
- Haslam J.
- Hastings B.
- Havinden-Williams M.
- Hawker L.
- Hayat A.
- Haynes R.
- Hays C.
- Haysom S.
- Hazelton T.
- Hazenberg P.
- Headon E.
- Hector G.
- Heddon S.
- Henry J.
- Henshall D.
- Hernandez F.
- Herrington W.
- Heslop P.
- Hester S.
- Hey S.
- Hey S.
- Heywood J.
- Hicks J.
- Hicks S.
- Higgins L.
- Hill P.
- Hilton J.
- Hindle A.
- Hindmarsh A.
- Hine P.
- Hird C.
- Hobson S.
- Hodgen L.
- Hodgkinson S.
- Hodgson H.
- Hodgson S.
- Hogg L.
- Hoggett L.
- Holden C.
- Holdhof N.
- Holland L.
- Hollands M.
- Holling N.
- Holmes R.
- Holt L.
- Hope S.
- Hopkins B.
- Horby P.W.
- Horrobin C.
- Horsley A.
- Horsley A.
- Hough M.
- Houghton C.
- Houghton K.
- Houlihan R.
- Housely K.
- How L.
- Howard L.
- Howard L.
- Howard M.
- Howard S.
- Howard-Sandy L.
- Howell A.
- Howie L.
- Hrycaiczuk J.
- Htwe S.
- Hudak A.
- Hudson H.
- Hughes G.
- Hughes H.
- Hughes S.
- Hulbert R.
- Hull D.
- Hull R.
- Hulme A.
- Hulme P.
- Hum R.
- Hunt L.
- Hunter E.
- Hunter K.
- Hunter N.
- Hunter S.
- Hurditch E.
- Hurley K.
- Hussain A.
- Hussain S.
- Hussain Y.
- Hussain Y.
- Hutchinson C.
- Hutton P.
- Hyslop M.
- Ibrahim A.
- Ibrahim M.
- Ijaz M.
- Ilyas F.
- Ingham J.
- Ingram T.
- Ionita A.
- Iqbal J.
- Iqbal M.
- Irons R.
- Irving R.
- Islam S.
- Islim A.
- Ismail O.
- Iwanikiw S.
- Jack C.
- Jackman S.
- Jackson B.
- Jackson S.
- Jacob J.
- Jacob P.
- Jacques N.
- Jafar A.
- Jagannathan V.
- Jaime F.
- Jaki T.
- Jaly Y.
- Jama R.
- Jamal A.
- Jamal S.
- James L.
- Jameson J.
- Janes K.
- Japp D.
- Jarman C.
- Jarvis C.
- Jarvis R.
- Jastrzebska P.
- Jeebun V.
- Jeffery K.
- Jeffreys N.
- Jeffs B.
- Jenkins P.
- Jennings F.
- Jennings V.
- Jerry D.
- Jimenez Gil A.
- Johal S.
- John A.
- John M.
- Johnson G.
- Johnston B.
- Johnston S.
- Johnstone D.
- Johnstone E.
- Jones A.
- Jones B.
- Jones E.
- Jones G.
- Jones J.
- Jones J.
- Jones P.
- Jones R.
- Jones S.
- Jones T.
- Jordache R.
- Jose S.
- Joseph G.
- Joseph R.
- Josiah B.
- Ju Wen Kwek A.
- Judge P.
- Juszczak E.
- Kailey A.
- Kalayi R.
- Kamath P.
- Kamfose M.
- Kanabar D.
- Kapoor R.
- Karunaratne N.
- Kaur J.
- Kausar Z.
- Kavanagh S.
- Kay S.
- Kayappurathu J.
- Ke M.
- Keating L.
- Keddie-Gray E.
- Kelly E.
- Kelly R.
- Kelly S.
- Kendall E.
- Kennedy A.
- Kennedy M.
- Keogan L.
- Khan A.
- Khan M.
- Khan M.
- Khan W.
- Khatun T.
- Khin H.
- Khurana C.
- Kibutu F.
- Kidd M.
- Kidney S.
- Kim M.
- Kimber A.
- King A.
- King J.
- King S.
- King-Oakley E.
- Kirk J.
- Kirkham E.
- Kirkpatrick L.
- Kitching T.
- Kitto L.
- Knight A.
- Knight F.
- Knight M.
- Knight S.
- Knowles C.
- Knowles L.
- Koch O.
- Koe Y.
- Koirata A.
- Kolakaluri E.
- Kononen M.
- Koo H.
- Kosmidis C.
- Kothandaraman E.
- Koukou K.
- Kountourgioti A.
- Krasauskas K.
- Krishnamurthy V.
- Krizak S.
- Krupej S.
- Kudsk-Iversen S.
- Kudzinskas A.
- Kumar R.
- Kurani A.
- Kurdy M.
- Kuriakose K.
- Kyere-Diabour T.
- Kyi N.
- Labao J.
- Lacson M.
- Ladan Z.
- Lagnado A.
- Lalloo D.
- Lalloo F.
- Lamb L.
- Lamb T.
- Landray M.J.
- Lane N.
- Lang A.
- Lang S.
- Langley M.
- Langoya C.
- Lassa S.
- Latham S.
- Latham V.
- Laurenson M.
- Law H.
- Lawless L.
- Lawrence G.
- Lawrence H.
- Lawrie R.
- Lay M.
- Lazo M.
- Le V.
- Leach L.
- Leandro L.
- Lee S.
- Lees D.
- Legge H.
- Leitch D.
- Lemoine N.
- Lennon K.
- Levett C.
- Levynska A.
- Lewis H.
- Lewis J.
- Lewis K.
- Lewis L.
- Lewis N.
- Liao A.
- Lim W.S.
- Linares C.
- Lindergard G.
- Lindergard G.
- Lindsay M.
- Lipscomb G.
- Lipscomb K.
- Little J.
- Liu P.
- Liu S.
- Lloyd A.
- Lloyd O.
- Lo S.
- Loader D.
- Lock S.
- Locke T.
- Lockett T.
- Lockett T.
- Lodhia K.
- Lofthouse M.
- Logan M.
- Logue C.A.
- Lokanathan S.
- Lomme K.
- Looby L.
- Lopez P.
- Lord R.
- Loro F.
- Lovell M.
- Low A.
- Low S.
- Lowe C.
- Lowsby R.
- Luintel A.
- Luke H.
- Luke J.
- Lunn M.
- Luo J.
- Lye A.
- Lyell B.
- Lynch D.
- Lynch D.
- Mabb H.
- Macfarlane J.
- Macfarlane J.
- Macfarlane L.
- Macfarlane L.
- MacInnes L.
- MacIntyre I.
- Mackay L.
- MacKenzie J.
- Mackey A.
- Mackintosh C.
- Macmahon M.
- MacRaild A.
- MacRaild A.
- Madden A.
- Madeja N.
- Mafham M.
- Magnaye L.
- Maharajh A.
- Mahaveer A.
- Mahdi H.
- Maheswaran A.
- Mahmood W.
- Mahmood Z.
- Mahony E.
- Mahungu T.
- Mair L.
- Majekdunmi T.
- Majumdar J.
- Malein F.
- Mancinelli R.
- Mandal S.
- Manderson L.
- Mandeville J.
- Mane T.
- Manso K.
- Mansour M.
- Marecka M.
- Maren D.
- Margabanthu G.
- Margaritopoulos G.
- Maria del Rocio F.
- Mariano V.
- Marks B.
- Marks P.
- Marriott C.
- Marriott N.
- Marsden P.
- Marshall A.
- Martin H.
- Martin K.
- Martin M.
- Martinez Garrido J.
- Maseda D.
- Mashate S.
- Masih S.
- Masoli M.
- Mathen S.
- Mather N.
- Mathew B.
- Mathews J.
- Mathioudakis A.
- Matila D.
- Matisa E.
- Matkins E.
- Matovu E.
- Matthews C.
- May P.
- Mayanagao I.
- Mayer J.
- Mayo T.
- Mazhani T.
- McAlinden P.
- McAndrew J.
- McBrearty C.
- McBride E.
- McCafferty G.
- McCann C.
- McCarthy E.
- McCorkindale A.
- McCrae J.
- McCullagh I.
- McCullagh L.
- McCullough K.
- McCullough S.
- McCurrach F.
- McDermott J.
- McDonald S.
- McDonnell N.
- McEleavy I.
- McEvoy E.
- McGhee C.
- McGrath B.
- McIntyre K.
- Mckie H.
- Mckie L.
- McLachlan H.
- McLarty N.
- McLeish M.
- McLure S.
- McMahon G.
- McMaster P.
- McMaster P.
- McMillan N.
- McMullen H.
- McNeill C.
- McNeill J.
- McNelis U.
- McNulty M.
- McSorland D.
- Mead J.
- Meakin O.
- Mears K.
- Mediana A.
- Medine R.
- Meghani N.
- Megson S.
- Mehar A.
- Mehra R.
- Meiring J.
- Melander S.
- Mellor F.
- Mellor Z.
- Melville A.
- Melville J.
- Membrey H.
- Mendonca C.
- Mentzer A.
- Meredith M.
- Merron P.
- Metcalfe B.
- Metryka A.
- Mew L.
- Mguni N.
- Miah N.
- Micallef D.
- Michalak N.
- Michalec O.
- Middle J.
- Middleton J.
- Middleton M.
- Millard J.
- Miller J.
- Millett L.
- Milligan H.
- Millington K.
- Millington S.
- Millward H.
- Minton J.
- Mishra A.
- Mishra B.
- Mistry H.
- Mital D.
- Mitchell B.
- Mitchelmore P.
- Mitra S.
- Moatt E.
- Mohamed O.
- Mohammed O.
- Mok J.
- Molina M.
- Molloy A.
- Monaghan H.
- Monsell K.
- Montasser M.
- Montgomery A.
- Moon A.
- Moon J.
- Moon J.
- Moonan M.
- Moore F.
- Moores R.
- Morales J.
- Moran L.
- Moray G.
- Morgan A.
- Morgan L.
- Morgan L.
- Morgan-Smith E.
- Morilla J.
- Morley W.
- Morris L.
- Morris P.
- Morris S.
- Morris S.
- Morrison S.
- Morrissey M.
- Morrow A.
- Moss S.
- Moth G.
- Motherwell N.
- Moulton H.
- Mounce G.
- Mtuwa S.
- Muazzam A.
- Mudawi D.
- Mulcahy M.
- Mulligan S.
- Mumford A.
- Munavvar M.
- Munt S.
- Murphy S.
- Murray C.
- Murray D.
- Murray I.
- Murray K.
- Murray L.
- Murthy M.
- Mutch C.
- Muzengi N.
- Mwaura E.
- Nafei M.
- Nagarajan T.
- Naglik L.
- Naguib M.
- Naicker K.
- Naisbitt J.
- Nandani A.
- Nandwani T.
- Nasa S.
- Natarajan N.
- Nathvani M.
- Navarra H.
- Naveed S.
- Naz M.
- Neal A.
- Nelson B.
- Nelson S.
- Nelson S.
- Nethercott D.
- Newby D.
- Newman T.
- Newport R.
- Ng S.
- Ngumo A.
- Nicholas N.
- Nicholas P.
- Nickson I.
- Nicol R.
- Nightingale T.
- Nilsson A.
- Ninan P.
- Nirmalan M.
- Nixon J.
- Nizam Ud Din K.
- Noe H.
- Norton R.
- Nourein K.
- Nunn K.
- Nunn M.
- Nunnick J.
- Nurgat Z.
- Nuttall A.
- Nwajiugo P.
- Oboh C.
- Obukofe R.
- Odam M.
- Odam M.
- Odedra K.
- Odell N.
- Offord P.
- Ohia U.
- Okeke T.
- OKell E.
- Oliver A.
- Oliver J.
- Oliver Z.
- Oomatia A.
- Oram R.
- Oreilly C.
- Osadcow A.
- Osanlou R.
- Osborne N.
- Osborne R.
- Osborne W.
- Osei-Bobie J.
- Oxlade R.
- O’Brien R.
- O’Callaghan C.
- O’Connor G.
- O’Donovan C.
- O’Farrell S.
- O’Riordan D.
- O’Sullivan E.
- Padden G.
- Page I.
- Page I.
- Page S.
- Pagett K.
- Pajak S.
- Pakou G.
- Palacios A.
- Palfrey H.
- Pandya T.
- Panes A.
- Pantin C.
- Parambil V.
- Parashar S.
- Parekh A.
- Parekh D.
- Parker B.
- Parker J.
- Parker S.
- Parkinson A.
- Passby L.
- Passey S.
- Patachako J.
- Patel M.
- Patel P.
- Patel S.
- Patience A.
- Patten S.
- Patterson C.
- Patterson L.
- Pauls L.
- Paulus S.
- Payne B.
- Payne E.
- Payne R.
- Peacock L.
- Pearce J.
- Pearson K.
- Peasley A.
- Peggie H.
- Pelham C.
- Penman C.
- Penman J.
- Penman R.
- Percival R.
- Perez E.
- Periyasamy L.
- Perry A.
- Perry M.
- Pessoa-Amorim G.
- Peters C.
- Peterson A.
- Peto L.
- Petrova B.
- Pezard-Snell M.
- Phelan P.
- Philbin J.
- Phillips N.
- PI M.
- Pick S.
- Pickard J.
- Pickering G.
- Piercy C.
- Pinches H.
- Pine K.
- Pinjala M.
- Pitchford M.
- Pleass R.
- Plowright M.
- Plumptre C.
- Pomery F.
- Poole L.
- Porter D.
- Porter D.
- Porter L.
- Potter A.
- Potts J.
- Poustie V.
- Power N.
- Poyner E.
- Pradhan V.
- Prady H.
- Prasath S.
- Pratt A.
- Pratt S.
- Preiss D.
- Prest C.
- Price A.
- Price C.
- Price D.
- Price K.
- Price L.
- Price V.
- Price-Eland R.
- Priest A.
- Prince C.
- Pringle S.
- Pristopan V.
- Priyash V.
- Prudon B.
- Pugh L.
- Purdue C.
- Purdy R.
- Pursell M.
- Purvis S.
- Putensen D.
- Pyart E.
- Quek E.
- Quigley J.
- Quindoyos J.
- Quinn T.
- Rabinowicz S.
- Rafique J.
- Rahman M.
- Rai S.
- Rai S.
- Raithatha A.
- Rajasri A.
- Ramanan A.
- Ramasamy M.
- Ramchandani A.
- Ramirez J.
- Rampling T.
- Ramsay J.
- Ramshaw A.
- Rana G.
- Rand J.
- Rank H.
- Rankhelawon R.
- Rasheed A.
- Ratcliffe S.
- Ratcliffe S.
- Raw J.
- Razvi Z.
- Redknap I.
- Redman N.
- Rees A.
- Rees M.
- Rees S.
- Rehman Z.
- Reilly M.
- Reith C.
- Renshaw S.
- Rey S.
- Reynard C.
- Reynolds H.
- Rhodes J.
- Rice E.
- Rice M.
- Rice N.
- Richardson E.
- Richardson N.
- Rigby L.
- Riley M.
- Riley P.
- Ripley D.
- Rishton C.
- Riste M.
- Ritchings A.
- Rivera Ortega P.
- Robbins E.
- Roberts V.
- Robertson C.
- Robertson J.
- Robertson N.
- Robinson J.
- Robinson L.
- Robinson S.
- Robson S.
- Roderick M.
- Rodger A.
- Rodgers A.
- Rodgers N.
- Rodgers P.
- Roehr C.
- Rogers J.
- Rogers S.
- Rogers T.
- Rook C.
- Rooney L.
- Rosby E.
- Rose A.
- Rose Z.
- Ross I.
- Rothman A.
- Rothwell J.
- Roughley L.
- Rowan K.
- Rowan N.
- Rowe A.
- Rowe N.
- Rowley M.
- Rudenko A.
- Rule R.
- Rushmer J.
- Ryan A.
- Ryan L.
- Ryan P.
- Rybka E.
- Ryder S.
- Salberg A.
- Saleh M.
- Salih H.
- Salman R.
- Salmon R.
- Sam M.
- Sam S.
- Saminathan S.
- Sammons E.
- Sammut D.
- Sampson J.
- Samuel M.
- Samuel Y.
- Sanchez Gonzalez A.
- Sanchez V.
- Sandercock P.
- Sangombe M.
- Sanju M.
- Santosh R.
- Sarfatti A.
- Sarkar R.
- Sarwar Z.
- Sathyanarayanan L.
- Saunderson A.
- Scaletta D.
- Scanlon D.
- Scarratt L.
- Scattergood S.
- Schadenberg A.
- Schafers J.
- Schafers J.
- Schneblen W.
- Schofield E.
- Schumacher N.
- Schunke N.
- Scobie A.
- Scoones T.
- Scott A.
- Scott C.
- Scullion A.
- Seaton I.
- Sedano J.
- Segovia M.
- Selby F.
- Sellers K.
- Sen N.
- Sengupta A.
- Sewdin T.
- Seymour J.
- Shah H.
- Shah R.
- Shah S.
- Shah S.
- Shaibu A.
- Shanahan T.
- Sharaf H.
- Sharma B.
- Sharma O.
- Sharma S.
- Sharma S.
- Sharp L.
- Sharratt P.
- Shaw D.
- Shaw D.
- Shaw J.
- Shawcross A.
- Shea D.O.
- Sheffield J.
- Shehata Z.
- Shenton J.
- Shepherd A.
- Shepherd A.
- Shepherd K.
- Shepherd L.
- Sheppeard R.
- Sheridan H.
- Sheridan R.
- Sherwin S.
- Shibly S.
- Shiham F.
- Shilladay C.
- Shillitoe B.
- Shioi C.
- Shirley K.
- Shurlock J.
- Shurmer J.
- Siamia L.
- Siddle E.
- Sime R.
- Simpson A.
- Simpson D.
- Simpson J.
- Simpson M.
- Simpson P.
- Sinclair S.
- Singh C.
- Singh S.
- Singhal P.
- Sithiravel S.
- Sivanadarajah S.
- Skaria A.
- Skehan N.
- Skinner T.
- Skinner V.
- Skorko A.
- Slack A.
- Slade H.
- Small E.
- Smallridge A.
- Smart B.
- Smith C.
- Smith C.
- Smith E.
- Smith H.
- Smith H.
- Smith J.
- Smith L.
- Smith L.
- Smith M.
- Smith N.
- Smith P.
- Smith R.
- Smith S.
- Smith T.
- Smith V.
- Snell D.
- Sobande T.
- Sobrino Diaz A.
- Solly R.
- Soni G.
- Soor P.
- Soothill G.
- Soren J.
- Spiller W.
- Spring O.
- Squires G.
- Squires J.
- Squires R.
- Squires R.
- Srinivasan R.
- Stagg W.
- Stanton A.
- Staplin N.
- Starnes D.
- Steer J.
- Stefania V.
- Stefanowska P.
- Stephens A.
- Stephensen D.
- Stephenson E.
- Sterrenburg M.
- Stevens W.
- Stevenson A.
- Stevenson S.
- Steward M.
- Stewart C.
- Stewart C.
- Stewart K.
- Stewart K.
- Stewart R.
- Stickley J.
- Stirrup S.
- Stock S.
- Stock S.
- Stockdale A.
- Stone B.
- Stone S.
- Storey I.
- Stratton E.
- Stratton J.
- Stubbs A.
- Stuttard M.
- Subudhi C.
- Sugden P.
- Sukumaran A.
- Sundar S.
- Surtees M.
- Sutherland R.
- Sutherland S.
- Sutu M.
- Swanson-Low C.
- Swart T.
- Swift E.
- Swist-Szulik K.
- Sykes D.
- Sykes E.
- Symon D.
- Syndercombe A.
- T-Michael H.
- Tadros M.
- Tague L.
- Tahir H.
- Tait J.
- Talbot P.
- Tallent R.
- Tallon B.
- Tanney C.
- Tanton E.
- Taribagil P.
- Tarr E.
- Tasiou A.
- Tate A.
- Taylor C.
- Taylor J.
- Taylor J.
- Taylor K.
- Taylor L.
- Taylor R.
- Taylor R.
- Taylor-Siddons M.
- Teasdale F.
- Teasdale J.
- Teasdale K.
- Tebbutt J.
- Telfer A.
- Tempany J.
- Tereszkowski-Kaminski R.
- Tewkesbury D.
- Thake M.
- Thakker M.
- Thamu B.
- Thet P.
- Thomas A.
- Thomas E.
- Thomas K.
- Thomas R.
- Thomas S.
- Thompson E.
- Thompson J.
- Thompson K.
- Thompson R.
- Thornton D.
- Thornton J.
- Thornton S.
- Thorpe S.
- Thrasyvoulou L.
- Thraves H.
- Thu-Ta P.
- Thwaites G.
- Tilbey S.
- Timerick J.
- Timmins A.
- Tinkler H.
- Tipper J.
- Tivenan H.
- Todd S.
- Todd S.
- Tohfa M.
- Toohey C.
- Topham K.
- Topping M.
- Tousis R.
- Trevelyan M.
- Trewick N.
- Truell R.
- Tsakiridou K.
- Tsang C.
- Tucker S.
- Tufail A.
- Tuff J.
- Tully R.
- Turbitt K.
- Turgut T.
- Turner G.
- Turner K.
- Turner S.
- Turner-Bone I.
- Turney S.
- Tyer A.
- Ul Haq M.
- Ul Hassan W.
- Underwood C.
- Unsworth A.
- Uriel A.
- Usher R.
- Ustianowski A.
- Ustianowski A.
- Vankayalapati P.
- Van’t Hoff W.
- Varghese M.
- Varnier G.
- Vasu V.
- Vatish M.
- Veerasamy S.
- Velankar S.
- Vella N.
- Velugupati A.
- Venables I.
- Venditti M.
- Veres M.
- Vergnano S.
- Vernall R.
- Verula J.
- Vethanayagam N.
- Vettikumaran S.
- Victoria S.
- Vinay S.
- Vincent O.
- Vincent R.
- Vyras E.
- Wade P.
- Waite A.
- Walden A.
- Walker I.
- Walker K.
- Walker S.
- Walker S.
- Wallace G.
- Wallendszus K.
- Wallis G.
- Walsh D.
- Walters J.
- Walton E.
- Walton O.
- Wang N.
- Wang R.
- Wang S.
- Warburton S.
- Ward J.
- Ward L.
- Ward R.
- Wardle S.
- Warmington J.
- Warner C.
- Warran S.
- Warren R.
- Warren Y.
- Warris A.
- Wasson E.
- Waterfall H.
- Waters D.
- Watson A.
- Watson E.
- Watson J.G.R.
- Watson L.
- Watson R.
- Watterson D.
- Watts M.
- Waugh V.
- Wayman E.
- Weatherhead M.
- Webb C.
- Webster I.
- Weerakoon R.
- Weetman M.
- Wei S.
- Welch J.
- Welch S.
- Wels R.
- Welters I.
- Welton R.
- Wentworth L.
- West R.
- West R.
- West S.
- Western L.
- Westhead R.
- Weston H.
- Wetherill B.
- White A.
- Whitehead C.
- Whitehouse A.
- Whitehouse T.
- Whiteley J.
- Whiteley S.
- Whittaker E.
- Whittle H.
- Whittle R.
- Wignall C.
- Wilcock D.
- Wilcock E.
- Wild S.
- Wilding L.
- Wilding P.
- Wildsmith T.
- Wiles J.
- Wilkins S.
- Wilkinson S.
- Wilkinson S.
- Wilkinson T.
- Williams A.
- Williams A.
- Williams E.
- Williams J.
- Williams J.
- Williams K.
- Williams M.
- Williams P.
- Williams S.
- Williams S.
- Williams T.
- Williamson D.
- Williamson J.
- Willis E.
- Willis H.
- Willis J.
- Wilson B.
- Wilson K.
- Wilson L.
- Win K.
- Winder L.
- Winter H.
- Wishlade T.
- Witele E.
- Withers N.
- Wittes J.
- Wong A.
- Wong C.
- Wong E.
- Wong N.
- Wood A.
- Wood C.
- Wood J.
- Wood L.
- Woodfield R.
- Woodford E.
- Woodford J.
- Woodhead L.
- Woodward Z.
- Woodward Z.
- Wooldridge G.
- Woollen L.
- Wootton D.
- Worton S.
- Wren L.
- Wright F.
- Wright R.
- Wubetu J.
- Xavier B.
- Yaqoob N.
- Yasmin S.
- Yates B.
- Yates T.
- Yelnoorkar F.
- Yelnoorkar F.
- Yeoh A.
- Younes Ibrahim A.
- Young L.
- Yu C.
- Zaki K.
- Zammit-Mangion M.
- Zayed M.
- Zhu D.
- Zia M.
- Zitter L.
- Zuhra N.
- Zullo C.
- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 31/01/2024
- Field of study
Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- Author
- Abbas M.
- Abdul Rasheed A.
- Abdul A.
- Abdul-Kadir R.
- Abdusamad K.
- Abernethy K.
- Aboelela H.
- Abouzaid M.
- Abraham M.
- Abraham T.
- Abrams J.
- Abu H.
- Abu-Arafeh A.
- Acton C.
- Adam F.
- Adam M.
- Adams C.
- Adams D.
- Adams L.
- Addo A.
- Adedeji O.
- Adegoke K.
- Adewunmi E.
- Adeyemo T.
- Agbeko R.
- Aggarwal S.
- Ahmad S.
- Ahmed A.
- Ahmed I.
- Ahmed M.
- Ahmed R.
- Ainsworth M.
- Ajmi A.
- Akili S.
- Al Aaraj A.
- Al Balushi A.
- Al-Asadi A.
- Al-Khalil M.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Sheklly B.
- Albert P.
- Alegria A.
- Alexander A.
- Alexander P.
- Alhabsha O.
- Ali M.
- Aliberti E.
- Alin J.
- Aliyuda F.
- Alkhudhayri A.
- Allan N.
- Allanson A.
- Allen E.
- Allen L.
- Alshaer I.
- Altaf S.
- Amezaga M.
- Amin A.
- Amit B.
- Anand A.
- Anantapatnaikuni S.
- Anderson L.
- Anderson M.
- Anderson N.
- Anderson R.
- Andrews A.
- Ang A.
- Anguvaa L.
- Aniruddhan K.
- Antonina Z.
- Araujo M.
- Archer A.
- Archer S.
- Arimoto R.
- Arkley C.
- Armah C.
- Armistead J.
- Armstrong C.
- Arnison-Newgass C.
- Arora D.
- Arya A.
- Arya R.
- Asghar A.
- Ashbrook-Raby C.
- Asher G.
- Ashley D.
- Ashraf S.
- Ashton D.
- Ashworth R.
- Aslam A.
- Atomode A.
- Attubato E.
- Aubrey P.
- Aujayeb A.
- Aung N.
- Avery M.
- Avram C.
- Aya A.
- Ayaz E.
- Aziz G.
- Babatunde F.
- Babington G.
- Bachour M.
- Badhan G.
- Bae J.
- Bagley G.
- Bagshaw L.
- Bailey A.
- Baillie J.
- Baillie J. Kenneth
- Baird D.
- Bajandouh A.
- Baker D.
- Baker K.
- Bakere H.
- Bakhai A.
- Balasingam P.
- Balaskas T.
- Balasubramaniam M.
- Balcombe A.
- Baldwin A.
- Baldwin-Jones R.
- Balfour J.
- Balmforth C.
- Baluwala A.
- Bamford A.
- Bancroft H.
- Banda J.
- Banks H.
- Banks P.
- Bannister O.
- Baptist M.
- Barclay C.
- Barker D.
- Barker J.
- Barker-Williams K.
- Barnacle J.
- Barnard A.
- Barnes R.
- Barnett-Vanes A.
- Barr A.
- Barr D.
- Barrera M.
- Barrett A.
- Barrow E.
- Bartholomew J.
- Bartlett G.
- Bartley S.
- Barton J.
- Barton L.
- Baruah R.
- Bashir H.
- Bashyal A.
- Basoglu A.
- Bassett J.
- Bateman K.
- Bates M.
- Batra D.
- Baxter M.
- Bazaz R.
- Beacham L.
- Beadon K.
- Beard K.
- Beaumont-Jewell D.
- Beazley C.
- Beddall H.
- Beddows S.
- Beer S.
- Beety J.
- Bega G.
- Begg S.
- Behrouzi R.
- Belcher J.
- Belfield K.
- Bell J.
- Bell N.
- Bellamy M.
- Bellamy T.
- Bendall L.
- Benetti N.
- Bennett A.
- Bennett M.
- Benson V.
- Bentley A.
- Beranova E.
- Beresford M.
- Bergin C.
- Bernatoniene J.
- Best K.
- Bhadi A.
- Bhagani S.
- Bhandal K.
- Bhandari A.
- Bhat A.
- Bhojwani D.
- Biggs S.
- Biju A.
- Bikov A.
- Birch C.
- Birchall K.
- Biswas N.
- Black P.
- Blackgrove H.
- Blackledge B.
- Blackley S.
- Blackman H.
- Blackstock C.
- Blair C.
- Blamey H.
- Blane S.
- Blazeby J.
- Blencowe N.
- Bloss A.
- Blunt T.
- Bobie B.
- Bobruk K.
- Boehmer G.
- Bohnacker N.
- Bokhari S.
- Bond H.
- Boothroyd M.
- Bostock K.
- Boumrah T.
- Bourke S.
- Bowes A.
- Bowker P.
- Bowler H.
- Bowman L.
- Bowman S.
- Bowring A.
- Boyd J.
- Boyle P.
- Bracken A.
- Bradley P.
- Bradley-Potts J.
- Brady S.
- Braithwaite M.
- Brankin-Frisby T.
- Bray F.
- Brear T.
- Brend M.
- Bretland G.
- Bridgwood G.
- Bright J.
- Broadhurst R.
- Brockelsby C.
- Brockley T.
- Brodsky M.
- Brokke F.
- Brookes M.
- Brooks S.
- Brown J.
- Brown N.
- Brown R.
- Brraka A.
- Bruce J.
- Bruce M.
- Brudlo W.
- Buch Maya H.
- Buchan R.
- Buck A.
- Buck L.
- Buckley L.
- Bugg G.
- Bujazia R.
- Bullock E.
- Burda D.
- Burden T.
- Burgess S.
- Burman A.
- Burston C.
- Burton A.
- Butler E.
- Butler J.
- Butler P.
- Butt M.
- Button H.
- Buttress D.
- Byrne J.
- Byrne W.
- Byrne-Watts V.
- Cale E.
- Calisti G.
- Callens C.
- Cameron E.
- Cameron S.
- Camm C.
- Cammack R.
- Campbell Hewson Q.
- Campbell B.
- Campbell D.
- Campbell H.
- Campbell Mark
- Campbell R.
- Cann A.
- Cannon A.
- Cantliff J.
- Caplin B.
- Capp A.
- Carey C.
- Carey R.
- Carley S.
- Carmody M.
- Carnahan M.
- Carrington Z.
- Carroll A.
- Carson R.
- Carter J.
- Carter P.
- Carty C.
- Carty L.
- Casey S.
- Cate H.
- Caws C.
- Central Coordinating Office (for the RECOVERY Collaborative Group)
- Century H.
- Chadwick J.
- Chakkarapani E.
- Chakraborty A.
- Chamberlain S.
- Chambers E.
- Chambers L.
- Chan E.
- Chan R.
- Chaplin J.
- Chapman G.
- Chapman K.
- Chapman L.
- Chapman P.
- Chappell L.
- Charles B.
- Charlton D.
- Chatar K.
- Chatterton D.
- Chaudhuri N.
- Chauhan R.
- Chawla V.
- Chen F.
- Cheng F.
- Cherrie M.
- Cheung E.
- Cheyne C.
- Chilcott S.
- Chilvers A.
- Chin K.
- Chineka R.
- Chinonso E.
- Chisnall B.
- Chiswick C.
- Chivima B.
- Chmiel C.
- Chrisopoulou A.
- Christian P.
- Christides A.
- Christmas D.
- Church E.
- Cianci N.
- Cicconi P.
- Clare E.
- Clark E.
- Clark G.
- Clark J.
- Clark L.
- Clark R.
- Clarke A.
- Clarke R.
- Clarke S.
- Clay K.
- Clayton-Smith J.
- Cleaver C.
- Clemente de la Torre C.
- Clifford S.
- Coakley M.
- Cobain K.
- Cochrane P.
- Cocks S.
- Coe A.
- Coey D.
- Cohen D.
- Coker O.
- Cole J.
- Coleman G.
- Coles H.
- Collier D.
- Collini Paul
- Collins J.
- Collins V.
- Colton H.
- Condliffe R.
- Connell E.
- Connell L.
- Connelly K.
- Connolly G.
- Connor E.
- Conroy K.
- Conteh V.
- Conway R.
- Cook E.
- Cooke G.
- Cooke H.
- Cooper D.
- Cooper L.
- Cooper N.
- Cooray S.
- Corbett C.
- Corbishley A.
- Cornwell J.
- Corr A.
- Corredera M.
- Corrigan R.
- Cosier T.
- Coston C.
- Cotterill D.
- Coull A.
- Courtney E.
- Cowen L.
- Cowman S.
- Cox E.
- Coy K.
- Cradduck-Bamford A.
- Crasta S.
- Crause J.
- Crawford A.
- Crawford E.
- Crawshaw S.
- Creagh-Brown B.
- Cremona J.
- Cribb M.
- Crichton C.
- Crisp L.
- Crisp N.
- Crosby H.
- Cross T.
- Crotty S.
- Cruickshank C.
- Cruise J.
- Cryans D.
- Cui G.
- Cui H.
- Cummings-Fosong G.
- Curran S.
- Currie J.
- Currie S.
- Curtis K.
- Curtis T.
- Czylok P.
- Daglish J.
- Dalgleish H.
- Dalton M.
- Damm E.
- Darbyshire Janet
- Darnell S.
- Darton T.
- Das S.
- Dasgin J.
- Data Monitoring Committee of the RECOVERY Collaborative Group
- Daunt A.
- Dave V.
- Davey M.
- Davidson N.
- Davies B.
- Davies C.
- Davies J.
- Davies K.
- Davies N.
- Davies P.
- Davies R.
- Davis A.
- Davis J.
- Davis P.
- Dawe C.
- Dawson A.
- Day Jeremy
- de Fonseka D.
- de Silva T.
- De Soyza A.
- de Vos J.
- Dean K.
- Deane J.
- Dear J.
- Deelchand V.
- Deery J.
- DeMets David
- Denis E.
- Dent M.
- Denton E.
- Denwood T.
- Dermody S.
- Desai A.
- Deshpande S.
- Dey P.
- Dhaliwal K.
- Dhani S.
- Dhasmana Devesh J.
- Dhillon R.
- Dicks P.
- Digby J.
- Dimitri P.
- Dismore L.
- Ditchfield L.
- Dixon C.
- Dixon K.
- Dobbie L.
- Dobson C.
- Dobson L.
- Docherty M.
- Dockrell D.
- Dodds R.
- Dodds S.
- Dolan D.
- Dolman M.
- Donald L.
- Donaldson D.
- Donaldson K.
- Donlon S.
- Donohoe A.
- Donohoe G.
- Dosani M.
- Dosanjh D.
- Dowden L.
- Dowling S.
- Downey R.
- Downs L.
- Dowson S.
- Drake C.
- Drewett O.
- Drogan H.
- Drummond G.
- Druryk K.
- Du Thinh A.
- Duckles-Leech H.
- Duffield E.
- Duffy H.
- Duggan A.
- Dummer S.
- Duncan C.
- Duncan F.
- Duncan G.
- Duncan R.
- Dunleavy J.
- Dunn A.
- Duran B.
- Durrans L.
- Durrington H.
- Duru I.
- Dymond H.
- D’Costa J.
- D’Mello A.
- Eades C.
- Early J.
- Eatough R.
- Eddleston M.
- Edgerley K.
- Edmond N.
- Edwards C.
- Edwards J.
- Ehiorobo L.
- Ekoi M.
- Elbeshy M.
- Elenwa U.
- Elgohary A.
- Ellis C.
- Ellwood A.
- Elokl M.
- Elsefi T.
- Elyoussfi S.
- Emberson Jonathan R.
- Emms M.
- Emond F.
- Emonts M.
- Essa F.
- Evans B.
- Evans G.
- Evans M.
- Evans R.
- Everden C.
- Everden S.
- Evison L.
- Ezenduka C.
- Fairbairn I.
- Fairclough A.
- Falconer E.
- Faluyi D.
- Fancois V.
- Farmery T.
- Farooq H.
- Farrell B.
- Farzana S.
- Fatemi A.
- Fatemi M.
- Faust S. N.
- Faust Saul N.
- Fearby S.
- Felton T.
- Fenlon K.
- Fenn A.
- Fenner I.
- Fenton C.
- Ferenando G.
- Ferguson C.
- Ferguson S.
- Ferguson V.
- Fernandez Lopez S.
- Ferriman E.
- Ferron S.
- Fethers N.
- Fielding J.
- Finch S.
- Fineman N.
- Finn A.
- Fiouni S.
- Fisher J.
- Fitzgerald F.
- Flaherty J.
- Fleming L.
- Fletcher L.
- Fogarty G.
- Foot H.
- Fordham I.
- Forrest A.
- Forster E.
- Foster E.
- Foster R.
- Fowler Robert
- Fowler S.
- Fox A.
- Fox C.
- Fox S.
- Frake R.
- Francis S.
- Frankland H.
- Franklin J.
- Franklin S.
- Freeman H.
- Freeman N.
- Frise M.
- Froud O.
- Fullerton D.
- G N.
- Gabbitas E.
- Gabriel C.
- Gabriel Z.
- Gale C.
- Gale H.
- Gallagher B.
- Gamble L.
- Gan C.
- Garden E.
- Gardiner P.
- Gardiner S.
- Garg I.
- Garty F.
- Gaughan E.
- Geele F.
- George B.
- George S.
- George V.
- Georgiou D.
- Gerdes L.
- Gettings S.
- Giannopoulou S.
- Gibani M.
- Gibb C.
- Gibbison B.
- Gibbons K.
- Gibson A.
- Gill L.
- Gillesen A.
- Gillian A.
- Gilliland D.
- Gillott R.
- Gilmour K.
- Gipson A.
- Glasgow S.
- Glover Bengtsson J.
- Glynn S.
- Gnanalingam C.
- Godden E.
- Godson E.
- Goldacre R.
- Goodall J.
- Goodenough B.
- Goodwin E.
- Goodwin J.
- Goonasekara M.
- Gorsuch T.
- Gosai J.
- Gotham D.
- Gould N.
- Gould S.
- Gourbault L.
- Gowans S.
- Gower H.
- Graham J.
- Grahamslaw J.
- Grana G.
- Grant A.
- Grant D.
- Gray A.
- Gray G.
- Gray J.
- Gray K.
- Grayson A.
- Green A.
- Green C.
- Green Christopher A.
- Green N.
- Greene D.
- Greenhalgh A.
- Gregory K.
- Greig J.
- Gresty J.
- Grey G.
- Griffin B.
- Griffin M.
- Grobovaite E.
- Groome R.
- Grover H.
- Grubb N.
- Grundy J.
- Guerin J.
- Gureviciute A.
- Gurung Rai S.
- Gurung L.
- Hackney P.
- Hadfield D.
- Hadfield S.
- Haider N.
- Haigh K.
- Haile V.
- Hainey S.
- Hall A.
- Hall C.
- Hall E.
- Hall J.
- Hallas J.
- Halls H.
- Hamdollah-Zadeh M.
- Hameed B.
- Hamid I.
- Hamilton G.
- Hamilton M.
- Hamilton S.
- Hammans B.
- Hammersley S.
- Hammond S.
- Hamoodi I.
- Hampshire K.
- Hampson L.
- Hanci O.
- Handrean S.
- Handzewniak N.
- Haney S.
- Hanison E.
- Hannington A.
- Hanrath A.
- Hanson A.
- Hanson H.
- Hanson J.
- Hanson S.
- Harden L.
- Harding Z.
- Hardman S.
- Hargreaves C.
- Harin A.
- Harman T.
- Harper C.
- Harper H.
- Harris J.
- Harris M.
- Harrison D.
- Harrison M.
- Harrison R.
- Harrison S.
- Harrod E.
- Hartrey W.
- Harvey A.
- Harvey M.
- Haslam J.
- Hastings B.
- Havinden-Williams M.
- Hawker L.
- Hayat A.
- Haynes Richard
- Hays C.
- Haysom S.
- Hazelton T.
- Hazenberg P.
- Headon E.
- Health records (for the RECOVERY Collaborative Group)
- Hector G.
- Heddon S.
- Henry J.
- Henshall D.
- Hernandez F.
- Herrington W.
- Heslop P.
- Hester S.
- Hey S.
- Heywood J.
- Hicks J.
- Hicks S.
- Higgins L.
- Hill P.
- Hilton J.
- Hindle A.
- Hindmarsh A.
- Hine P.
- Hird C.
- Hobson S.
- Hodgen L.
- Hodgkinson S.
- Hodgson H.
- Hodgson S.
- Hogg L.
- Hoggett L.
- Holden C.
- Holdhof N.
- Holland L.
- Hollands M.
- Holling N.
- Holmes R.
- Holt L.
- Hope S.
- Hopkins B.
- Horby Peter W.
- Horrobin C.
- Horsley A.
- Hough M.
- Houghton C.
- Houghton K.
- Houlihan R.
- Housely K.
- How L.
- Howard L.
- Howard M.
- Howard S.
- Howard-Sandy L.
- Howell A.
- Howie L.
- Hrycaiczuk J.
- Htwe S.
- Hudak A.
- Hudson H.
- Hughes G.
- Hughes H.
- Hughes S.
- Hulbert R.
- Hull D.
- Hull R.
- Hulme A.
- Hulme P.
- Hum R.
- Hunt L.
- Hunter E.
- Hunter K.
- Hunter N.
- Hunter S.
- Hurditch E.
- Hurley K.
- Hussain A.
- Hussain S.
- Hussain Y.
- Hutchinson C.
- Hutton P.
- Hyslop M.
- Ibrahim A.
- Ibrahim M.
- Ijaz M.
- Ilyas F.
- Ingham J.
- Ingram T.
- Ionita A.
- Iqbal J.
- Iqbal M.
- Irons R.
- Irving R.
- Islam S.
- Islim A.
- Ismail O.
- Iwanikiw S.
- Jack C.
- Jackman S.
- Jackson B.
- Jackson S.
- Jacob J.
- Jacob P.
- Jacques N.
- Jafar A.
- Jagannathan V.
- Jaime F.
- Jaki Thomas
- Jaly Y.
- Jama R.
- Jamal A.
- Jamal S.
- James L.
- Jameson J.
- Janes K.
- Japp D.
- Jarman C.
- Jarvis C.
- Jarvis R.
- Jastrzebska P.
- Jeebun V.
- Jeffery Katie
- Jeffreys N.
- Jeffs B.
- Jenkins P.
- Jennings F.
- Jennings V.
- Jerry D.
- Jimenez Gil A.
- Johal S.
- John A.
- John M.
- Johnson G.
- Johnston B.
- Johnston S.
- Johnstone D.
- Johnstone E.
- Jones A.
- Jones B.
- Jones E.
- Jones G.
- Jones J.
- Jones P.
- Jones R.
- Jones S.
- Jones T.
- Jordache R.
- Jose S.
- Joseph G.
- Joseph R.
- Josiah B.
- Ju Wen Kwek A.
- Judge P.
- Juszczak Edmund
- Kailey A.
- Kalayi R.
- Kamath P.
- Kamfose M.
- Kanabar D.
- Kapoor R.
- Karunaratne N.
- Kaur J.
- Kausar Z.
- Kavanagh S.
- Kay S.
- Kayappurathu J.
- Ke M.
- Keating L.
- Keddie-Gray E.
- Kelly E.
- Kelly R.
- Kelly S.
- Kendall E.
- Kennedy A.
- Kennedy M.
- Keogan L.
- Khan A.
- Khan M.
- Khan W.
- Khatun T.
- Khin H.
- Khurana C.
- Kibutu F.
- Kidd M.
- Kidney S.
- Kim M.
- Kimber A.
- King A.
- King J.
- King S.
- King-Oakley E.
- Kirk J.
- Kirkham E.
- Kirkpatrick L.
- Kitching T.
- Kitto L.
- Knight A.
- Knight F.
- Knight Marian
- Knight S.
- Knowles C.
- Knowles L.
- Koch O.
- Koe Y.
- Koirata A.
- Kolakaluri E.
- Kononen M.
- Koo H.
- Kosmidis C.
- Kothandaraman E.
- Koukou K.
- Kountourgioti A.
- Krasauskas K.
- Krishnamurthy V.
- Krizak S.
- Krupej S.
- Kudsk-Iversen S.
- Kudzinskas A.
- Kumar R.
- Kurani A.
- Kurdy M.
- Kuriakose K.
- Kyere-Diabour T.
- Kyi N.
- Labao J.
- Lacson M.
- Ladan Z.
- Lagnado A.
- Lalloo David
- Lalloo F.
- Lamb L.
- Lamb T.
- Landray Martin J.
- Lane N.
- Lang A.
- Lang S.
- Langley M.
- Langoya C.
- Lassa S.
- Latham S.
- Latham V.
- Laurenson M.
- Law H.
- Lawless L.
- Lawrence G.
- Lawrence H.
- Lawrie R.
- Lay M.
- Lazo M.
- Le V.
- Leach L.
- Leandro L.
- Lee S.
- Lees D.
- Legge H.
- Leitch D.
- Lemoine N.
- Lennon K.
- Levett C.
- Levynska A.
- Lewis H.
- Lewis J.
- Lewis K.
- Lewis L.
- Lewis N.
- Liao A.
- Lim Wei Shen
- Linares C.
- Lindergard G.
- Lindsay M.
- Lipscomb G.
- Lipscomb K.
- Little J.
- Liu P.
- Liu S.
- Lloyd A.
- Lloyd O.
- Lo S.
- Loader D.
- Local Clinical Centre staff (for the RECOVERY Collaborative Group)
- Lock S.
- Locke T.
- Lockett T.
- Lodhia K.
- Lofthouse M.
- Logan M.
- Logue C. A.
- Lokanathan S.
- Lomme K.
- Looby L.
- Lopez P.
- Lord R.
- Loro F.
- Lovell M.
- Low A.
- Low S.
- Lowe C.
- Lowsby R.
- Luintel A.
- Luke H.
- Luke J.
- Lunn M.
- Luo J.
- Lye A.
- Lyell B.
- Lynch D.
- Mabb H.
- Macfarlane J.
- Macfarlane L.
- MacInnes L.
- MacIntyre I.
- Mackay L.
- MacKenzie J.
- Mackey A.
- Mackintosh C.
- Macmahon M.
- MacRaild A.
- Madden A.
- Madeja N.
- Mafham Marion
- Magnaye L.
- Maharajh A.
- Mahaveer A.
- Mahdi H.
- Maheswaran A.
- Mahmood W.
- Mahmood Z.
- Mahony E.
- Mahungu T.
- Mair L.
- Majekdunmi T.
- Majumdar Jaydip
- Malein Flora
- Mancinelli R.
- Mandal S.
- Manderson L.
- Mandeville J.
- Mane T.
- Manso K.
- Mansour M.
- Marecka M.
- Maren D.
- Margabanthu G.
- Margaritopoulos G.
- Maria del Rocio F.
- Mariano V.
- Marks B.
- Marks P.
- Marriott C.
- Marriott N.
- Marsden P.
- Marshall A.
- Martin H.
- Martin K.
- Martin M.
- Martinez Garrido J.
- Maseda D.
- Mashate S.
- Masih S.
- Masoli M.
- Mathen S.
- Mather N.
- Mathew B.
- Mathews J.
- Mathioudakis A.
- Matila D.
- Matisa E.
- Matkins E.
- Matovu E.
- Matthews C.
- May P.
- Mayanagao I.
- Mayer J.
- Mayo T.
- Mazhani T.
- McAlinden P.
- McAndrew J.
- McBrearty C.
- McBride E.
- McCafferty G.
- McCann C.
- McCarthy E.
- McCorkindale A.
- McCrae J.
- McCullagh I.
- McCullagh L.
- McCullough K.
- McCullough S.
- McCurrach F.
- McDermott J.
- McDonald S.
- McDonnell N.
- McEleavy I.
- McEvoy E.
- McGhee C.
- McGrath B.
- McIntyre K.
- Mckie H.
- Mckie L.
- McLachlan H.
- McLarty N.
- McLeish M.
- McLure S.
- McMahon G.
- McMaster P.
- McMillan N.
- McMullen H.
- McNeill C.
- McNeill J.
- McNelis U.
- McNulty M.
- McSorland D.
- Mead J.
- Meakin O.
- Mears K.
- Mediana A.
- Medine R.
- Meghani N.
- Megson S.
- Mehar A.
- Mehra R.
- Meiring J.
- Melander S.
- Mellor F.
- Mellor Z.
- Melville A.
- Melville J.
- Membrey H.
- Mendonca C.
- Mentzer A.
- Meredith M.
- Merron P.
- Metcalfe B.
- Metryka A.
- Mew L.
- Mguni N.
- Miah N.
- Micallef D.
- Michalak N.
- Michalec O.
- Middle J.
- Middleton J.
- Middleton M.
- Millard J.
- Miller J.
- Millett L.
- Milligan H.
- Millington K.
- Millington S.
- Millward H.
- Minton J.
- Mishra A.
- Mishra B.
- Mistry H.
- Mital D.
- Mitchell B.
- Mitchelmore P.
- Mitra S.
- Moatt E.
- Mohamed O.
- Mohammed O.
- Mok J.
- Molina M.
- Molloy A.
- Monaghan H.
- Monsell K.
- Montasser M.
- Montgomery Alan
- Moon A.
- Moon J.
- Moonan M.
- Moore F.
- Moores R.
- Morales J.
- Moran L.
- Moray G.
- Morgan A.
- Morgan L.
- Morgan-Smith E.
- Morilla J.
- Morley W.
- Morris L.
- Morris P.
- Morris S.
- Morrison S.
- Morrissey M.
- Morrow A.
- Moss S.
- Moth G.
- Motherwell N.
- Moulton H.
- Mounce G.
- Mtuwa S.
- Muazzam A.
- Mudawi D.
- Mulcahy M.
- Mulligan S.
- Mumford Andrew
- Munavvar Mohammed
- Munt S.
- Murphy S.
- Murray C.
- Murray D.
- Murray I.
- Murray K.
- Murray L.
- Murthy M.
- Mutch C.
- Muzengi N.
- Mwaura E.
- Nafei M.
- Nagarajan T.
- Naglik L.
- Naguib M.
- Naicker K.
- Naisbitt J.
- Nandani A.
- Nandwani T.
- Nasa S.
- Natarajan N.
- Nathvani M.
- Navarra H.
- Naveed S.
- Naz M.
- Neal A.
- Nelson B.
- Nelson S.
- Nethercott D.
- Newby D.
- Newman T.
- Newport R.
- Ng S.
- Ngumo A.
- Nicholas N.
- Nicholas P.
- Nickson I.
- Nicol R.
- Nightingale T.
- Nilsson A.
- Ninan P.
- Nirmalan M.
- Nixon J.
- Nizam Ud Din K.
- Noe H.
- Norton R.
- Nourein K.
- Nunn K.
- Nunn M.
- Nunnick J.
- Nurgat Z.
- Nuttall A.
- Nwajiugo P.
- Oboh C.
- Obukofe R.
- Odam M.
- Odedra K.
- Odell N.
- Offord P.
- Ohia U.
- Okeke T.
- OKell E.
- Oliver A.
- Oliver J.
- Oliver Z.
- Oomatia A.
- Oram R.
- Oreilly C.
- Osadcow A.
- Osanlou R.
- Osborne N.
- Osborne R.
- Osborne W.
- Osei-Bobie J.
- Oxlade R.
- O’Brien R.
- O’Callaghan C.
- O’Connor G.
- O’Donovan C.
- O’Farrell S.
- O’Riordan D.
- O’Sullivan E.
- Padden G.
- Page I.
- Page S.
- Pagett K.
- Pajak S.
- Pakou G.
- Palacios A.
- Palfrey H.
- Pandya T.
- Panes A.
- Pantin C.
- Parambil V.
- Parashar S.
- Parekh A.
- Parekh D.
- Parker B.
- Parker J.
- Parker S.
- Parkinson A.
- Passby L.
- Passey S.
- Patachako J.
- Patel M.
- Patel P.
- Patel S.
- Patience A.
- Patten S.
- Patterson C.
- Patterson L.
- Pauls L.
- Paulus S.
- Payne B.
- Payne E.
- Payne R.
- Peacock L.
- Pearce J.
- Pearson K.
- Peasley A.
- Peggie H.
- Pelham C.
- Penman C.
- Penman J.
- Penman R.
- Percival R.
- Perez E.
- Periyasamy L.
- Perry A.
- Perry M.
- Pessoa-Amorim Guilherme
- Peters C.
- Peterson A.
- Peto Leon
- Petrova B.
- Pezard-Snell M.
- Phelan P.
- Philbin J.
- Phillips N.
- PI M.
- Pick S.
- Pickard J.
- Pickering G.
- Piercy C.
- Pinches H.
- Pine K.
- Pinjala M.
- Pitchford M.
- Pleass R.
- Plowright M.
- Plumptre C.
- Pomery F.
- Poole L.
- Porter D.
- Porter L.
- Potter A.
- Potts J.
- Poustie V.
- Power N.
- Poyner E.
- Pradhan V.
- Prady H.
- Prasath S.
- Pratt A.
- Pratt S.
- Preiss D.
- Prest C.
- Price A.
- Price C.
- Price D.
- Price K.
- Price L.
- Price V.
- Price-Eland R.
- Priest A.
- Prince C.
- Pringle S.
- Pristopan V.
- Priyash V.
- Prudon Benjamin
- Pugh L.
- Purdue C.
- Purdy R.
- Pursell M.
- Purvis S.
- Putensen D.
- Pyart E.
- Quek E.
- Quigley J.
- Quindoyos J.
- Quinn T.
- Rabinowicz S.
- Rafique J.
- Rahman M.
- Rai S.
- Raithatha A.
- Rajasri A.
- Ramanan A.
- Ramasamy M.
- Ramchandani A.
- Ramirez J.
- Rampling T.
- Ramsay J.
- Ramshaw A.
- Rana G.
- Rand J.
- Rank H.
- Rankhelawon R.
- Rasheed A.
- Ratcliffe S.
- Raw J.
- Razvi Z.
- RECOVERY Collaborative Group
- Redknap I.
- Redman N.
- Rees A.
- Rees M.
- Rees S.
- Rehman Z.
- Reilly M.
- Reith C.
- Renshaw S.
- Rey S.
- Reynard C.
- Reynolds H.
- Rhodes J.
- Rice E.
- Rice M.
- Rice N.
- Richardson E.
- Richardson N.
- Rigby L.
- Riley M.
- Riley P.
- Ripley D.
- Rishton C.
- Riste M.
- Ritchings A.
- Rivera Ortega P.
- Robbins E.
- Roberts V.
- Robertson C.
- Robertson J.
- Robertson N.
- Robinson J.
- Robinson L.
- Robinson S.
- Robson S.
- Roderick M.
- Rodger A.
- Rodgers A.
- Rodgers N.
- Rodgers P.
- Roehr C.
- Rogers J.
- Rogers S.
- Rogers T.
- Rook C.
- Rooney L.
- Rosby E.
- Rose A.
- Rose Z.
- Ross I.
- Rothman A.
- Rothwell J.
- Roughley L.
- Rowan Kathryn
- Rowan N.
- Rowe A.
- Rowe N.
- Rowley M.
- Rudenko A.
- Rule R.
- Rushmer J.
- Ryan A.
- Ryan L.
- Ryan P.
- Rybka E.
- Ryder S.
- Salberg A.
- Saleh M.
- Salih H.
- Salman R.
- Salmon R.
- Sam M.
- Sam S.
- Saminathan S.
- Sammons E.
- Sammut D.
- Sampson J.
- Samuel M.
- Samuel Y.
- Sanchez Gonzalez A.
- Sanchez V.
- Sandercock Peter
- Sangombe M.
- Sanju M.
- Santosh R.
- Sarfatti A.
- Sarkar R.
- Sarwar Z.
- Sathyanarayanan L.
- Saunderson A.
- Scaletta D.
- Scanlon D.
- Scarratt L.
- Scattergood S.
- Schadenberg A.
- Schafers J.
- Schneblen W.
- Schofield E.
- Schumacher N.
- Schunke N.
- Scobie A.
- Scoones T.
- Scott A.
- Scott C.
- Scullion A.
- Seaton I.
- Sedano J.
- Segovia M.
- Selby F.
- Sellers K.
- Sen N.
- Sengupta A.
- Sewdin T.
- Seymour J.
- Shah H.
- Shah R.
- Shah S.
- Shaibu A.
- Shanahan T.
- Sharaf H.
- Sharma B.
- Sharma O.
- Sharma S.
- Sharp L.
- Sharratt P.
- Shaw D.
- Shaw J.
- Shawcross A.
- Shea D. O.
- Sheffield J.
- Shehata Z.
- Shenton J.
- Shepherd A.
- Shepherd K.
- Shepherd L.
- Sheppeard R.
- Sheridan H.
- Sheridan R.
- Sherwin S.
- Shibly S.
- Shiham F.
- Shilladay C.
- Shillitoe B.
- Shioi C.
- Shirley K.
- Shurlock J.
- Shurmer Jack
- Siamia L.
- Siddle E.
- Sime R.
- Simpson A.
- Simpson D.
- Simpson J.
- Simpson M.
- Simpson P.
- Sinclair S.
- Singh C.
- Singh S.
- Singhal P.
- Sithiravel S.
- Sivanadarajah S.
- Skaria A.
- Skehan N.
- Skinner T.
- Skinner V.
- Skorko A.
- Slack A.
- Slade H.
- Small E.
- Smallridge A.
- Smart B.
- Smith C.
- Smith E.
- Smith H.
- Smith J.
- Smith L.
- Smith M.
- Smith N.
- Smith P.
- Smith R.
- Smith S.
- Smith T.
- Smith V.
- Snell D.
- Sobande T.
- Sobrino Diaz A.
- Solly R.
- Soni G.
- Soor P.
- Soothill G.
- Soren J.
- Spiller W.
- Spring O.
- Squires G.
- Squires J.
- Squires R.
- Srinivasan R.
- Stagg W.
- Stanton A.
- Staplin Natalie
- Starnes D.
- Steer J.
- Stefania V.
- Stefanowska P.
- Stephens A.
- Stephensen D.
- Stephenson E.
- Sterrenburg M.
- Stevens W.
- Stevenson A.
- Stevenson S.
- Steward M.
- Stewart C.
- Stewart K.
- Stewart Richard
- Stickley J.
- Stirrup S.
- Stock S.
- Stockdale A.
- Stone B.
- Stone S.
- Storey I.
- Stratton E.
- Stratton J.
- Stubbs A.
- Stuttard M.
- Subudhi C.
- Sugden P.
- Sukumaran A.
- Sundar S.
- Surtees M.
- Sutherland R.
- Sutherland S.
- Sutu M.
- Swanson-Low C.
- Swart T.
- Swift E.
- Swist-Szulik K.
- Sykes D.
- Sykes E.
- Symon D.
- Syndercombe A.
- T-Michael H.
- Tadros M.
- Tague L.
- Tahir H.
- Tait J.
- Talbot P.
- Tallent R.
- Tallon B.
- Tanney C.
- Tanton E.
- Taribagil P.
- Tarr E.
- Tasiou A.
- Tate A.
- Taylor C.
- Taylor J.
- Taylor K.
- Taylor L.
- Taylor R.
- Taylor-Siddons M.
- Teasdale F.
- Teasdale J.
- Teasdale K.
- Tebbutt J.
- Telfer A.
- Tempany J.
- Tereszkowski-Kaminski R.
- Tewkesbury D.
- Thake M.
- Thakker M.
- Thamu B.
- Thet P.
- Thomas A.
- Thomas E.
- Thomas K.
- Thomas R.
- Thomas S.
- Thompson E.
- Thompson J.
- Thompson K.
- Thompson R.
- Thornton D.
- Thornton J.
- Thornton S.
- Thorpe S.
- Thrasyvoulou L.
- Thraves H.
- Thu-Ta P.
- Thwaites Guy
- Tilbey S.
- Timerick J.
- Timmins A.
- Tinkler H.
- Tipper J.
- Tivenan H.
- Todd S.
- Tohfa M.
- Toohey C.
- Topham K.
- Topping M.
- Tousis R.
- Trevelyan M.
- Trewick N.
- Truell R.
- Tsakiridou K.
- Tsang C.
- Tucker S.
- Tufail A.
- Tuff J.
- Tully R.
- Turbitt K.
- Turgut T.
- Turner G.
- Turner K.
- Turner S.
- Turner-Bone I.
- Turney S.
- Tyer A.
- UK National Institute for Health Research Clinical Research Network (for the RECOVERY Collaborative Group)
- Ul Haq M.
- Ul Hassan W.
- Underwood C.
- Unsworth A.
- Uriel Alison
- Usher R.
- Ustianowski A.
- Vankayalapati P.
- Van’t Hoff W.
- Varghese M.
- Varnier G.
- Vasu V.
- Vatish M.
- Veerasamy S.
- Velankar S.
- Vella N.
- Velugupati A.
- Venables I.
- Venditti M.
- Veres M.
- Vergnano S.
- Vernall R.
- Verula J.
- Vethanayagam N.
- Vettikumaran S.
- Victoria S.
- Vinay S.
- Vincent O.
- Vincent R.
- Vyras E.
- Wade P.
- Waite A.
- Walden A.
- Walker I.
- Walker K.
- Walker S.
- Wallace G.
- Wallendszus K.
- Wallis G.
- Walsh D.
- Walters J.
- Walton E.
- Walton O.
- Wang N.
- Wang R.
- Wang S.
- Warburton S.
- Ward J.
- Ward L.
- Ward R.
- Wardle S.
- Warmington J.
- Warner C.
- Warran S.
- Warren R.
- Warren Y.
- Warris Adilia
- Wasson E.
- Waterfall H.
- Waters D.
- Watson A.
- Watson E.
- Watson J. G. R.
- Watson L.
- Watson R.
- Watterson D.
- Watts M.
- Waugh V.
- Wayman E.
- Weatherhead M.
- Webb C.
- Webster I.
- Weerakoon R.
- Weetman M.
- Wei S.
- Welch J.
- Welch S.
- Wels R.
- Welters I.
- Welton R.
- Wentworth L.
- West R.
- West S.
- Western L.
- Westhead R.
- Weston H.
- Wetherill B.
- White A.
- Whitehead C.
- Whitehouse A.
- Whitehouse T.
- Whiteley J.
- Whiteley S.
- Whittaker E.
- Whittle H.
- Whittle R.
- Wignall C.
- Wilcock D.
- Wilcock E.
- Wild S.
- Wilding L.
- Wilding P.
- Wildsmith T.
- Wiles J.
- Wilkins S.
- Wilkinson S.
- Wilkinson T.
- Williams A.
- Williams E.
- Williams J.
- Williams K.
- Williams M.
- Williams P.
- Williams S.
- Williams T.
- Williamson D.
- Williamson J.
- Willis E.
- Willis H.
- Willis J.
- Wilson B.
- Wilson K.
- Wilson L.
- Win K.
- Winder L.
- Winter H.
- Wishlade T.
- Witele E.
- Withers N.
- Wittes Janet
- Wong A.
- Wong C.
- Wong E.
- Wong N.
- Wood A.
- Wood C.
- Wood J.
- Wood L.
- Woodfield R.
- Woodford E.
- Woodford J.
- Woodhead L.
- Woodward Z.
- Wooldridge G.
- Woollen L.
- Wootton D.
- Worton S.
- Wren L.
- Wright F.
- Wright R.
- Wubetu J.
- Xavier B.
- Yaqoob N.
- Yasmin S.
- Yates Bryan
- Yates T.
- Yelnoorkar F.
- Yeoh A.
- Younes Ibrahim A.
- Young L.
- Yu C.
- Zaki K.
- Zammit-Mangion M.
- Zayed M.
- Zhu D.
- Zia M.
- Zitter L.
- Zuhra N.
- Zullo C.
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome
The perceived impact of Covid-19 on periodontal practice in the United Kingdom: a questionnaire study
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/11/2020
- Field of study