POOL File Catalog, Collection and Metadata Components

The POOL project is the common persistency framework for the LHC experiments to store petabytes of experiment data and metadata in a distributed and grid enabled way. POOL is a hybrid event store consisting of a data streaming layer and a relational layer. This paper describes the design of file catalog, collection and metadata components which are not part of the data streaming layer of POOL and outlines how POOL aims to provide transparent and efficient data access for a wide range of environments and use cases - ranging from a large production site down to a single disconnected laptops. The file catalog is the central POOL component translating logical data references to physical data files in a grid environment. POOL collections with their associated metadata provide an abstract way of accessing experiment data via their logical grouping into sets of related data objects.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 4 pages, 1 eps figure, PSN MOKT00

Mit Links in den Shareholder-Kapitalismus?

Wer verpflichtet die Aktiengesellschaften? Und wem sind sie verpflichtet? In nahezu allen westlichen Industrieländern werden derzeit die Rechte der Hauptversammlungen und Aufsichtsorgane gestärkt, Übernahmen erleichtert, Minderheitsaktionäre besser geschützt und Auflagen zur Transparenz verschärft. Warum aber machen sich gerade sozialdemokratische Parteien für diese aktionärsorientierten Reformen stark

A stacked ensemble learning and non-homogeneous hidden Markov model for daily precipitation downscaling and projection

Global circulation models (GCMs) are routinely used to project future climate conditions worldwide, such as temperature and precipitation. However, inputs with a finer resolution are required to drive impact-related models at local scales. The nonhomogeneous hidden Markov model (NHMM) is a widely used algorithm for the precipitation statistical downscaling for GCMs. To improve the accuracy of the traditional NHMM in reproducing spatiotemporal precipitation features of specific geographic sites, especially extreme precipitation, we developed a new precipitation downscaling framework. This hierarchical model includes two levels: (1) establishing an ensemble learning model to predict the occurrence probabilities for different levels of daily precipitation aggregated at multiple sites and (2) constructing a NHMM downscaling scheme of daily amount at the scale of a single rain gauge using the outputs of ensemble learning model as predictors. As the results obtained for the case study in the central-eastern China (CEC), show that our downscaling model is highly efficient and performs better than the NHMM in simulating precipitation variability and extreme precipitation. Finally, our projections indicate that CEC may experience increased precipitation in the future. Compared with around 26 years (1990–2015), the extreme precipitation frequency and amount would significantly increase by 21.9%– 48.1% and 12.3%–38.3%, respectively, by the late century (2075–2100) under the Shared Socioeconomic Pathway 585 climate scenario

The evolution of mass loaded supernova remnants: II. Temperature dependent mass injection rates

We investigate the evolution of spherically symmetric supernova remnants in which mass loading takes place due to conductively driven evaporation of embedded clouds. Numerical simulations reveal significant differences between the evolution of conductively mass loaded and the ablatively mass loaded remnants studied in Paper I. A main difference is the way in which conductive mass loading is extinguished at fairly early times, once the interior temperature of the remnant falls below ~ 107 K. Thus, at late times remnants that ablatively mass load are dominated by loaded mass and thermal energy, while those that conductively mass load are dominated by swept-up mass and kinetic energy. Simple approximations to the remnant evolution, complementary to those in Paper I, are given

Desempenho e características de carcaça de bovinos F1 Pardo Suiço corte x Nelore, inteiros ou castrados em diferentes idades.

Foram avaliados o desempenho e as características de carcaça de 104 bovinos F1 pardo suíço corte x nelore, distribuídos, a partir do nascimento, em cinco tratamentos: castração ao nascimento, castração ao desmame, castração aos doze meses, castração aos dezoito meses e não castrados . Os animais foram criados em pastagens (perenes) cultivadas, com suplementação na primeira seca e terminação em confinamento na segunda seca. O ponto de abate foi estipulado para um mínimo de 460 quilos de peso vivo e 3 milímetros de gordura de cobertura, sendo esta medida por ultra-sonografia. Não houve diferenças entre os tratamentos (P>0,05) para ganho diário e peso vivo do nascimento aos dezoito meses de idade e durante o período de engorda em confinamento. Entretanto, animais inteiros mostraram um melhor desempenho (P<0,05) do que os castrados no período de dezoito a vinte meses de idade. Não houve influencia (P<0,05) da idade de castração sobre as características de carcaça, mas animais castrados foram superiores (P<0,05) aos animais inteiros em termos de acabamento e proporção de traseiro. Por outro lado, os inteiros apresentaram melhor rendimento de carcaça (P<0,05) que os castrados, independente da época da castração.bitstream/item/104670/1/Desempenho-e-caracteristicas-de-carcaca.pd

Amphotericin forms an extramembranous and fungicidal sterol sponge.

For over 50 years, amphotericin has remained the powerful but highly toxic last line of defense in treating life-threatening fungal infections in humans with minimal development of microbial resistance. Understanding how this small molecule kills yeast is thus critical for guiding development of derivatives with an improved therapeutic index and other resistance-refractory antimicrobial agents. In the widely accepted ion channel model for its mechanism of cytocidal action, amphotericin forms aggregates inside lipid bilayers that permeabilize and kill cells. In contrast, we report that amphotericin exists primarily in the form of large, extramembranous aggregates that kill yeast by extracting ergosterol from lipid bilayers. These findings reveal that extraction of a polyfunctional lipid underlies the resistance-refractory antimicrobial action of amphotericin and suggests a roadmap for separating its cytocidal and membrane-permeabilizing activities. This new mechanistic understanding is also guiding development of what are to our knowledge the first derivatives of amphotericin that kill yeast but not human cells

Metalanguage in L1 English-speaking 12-year-olds: which aspects of writing do they talk about?

Traditional psycholinguistic approaches to metalinguistic awareness in L1 learners elicit responses containing metalanguage that demonstrates metalinguistic awareness of pre-determined aspects of language knowledge. This paper, which takes a more ethnographic approach, demonstrates how pupils are able to engage their own focus of metalanguage when reflecting on their everyday learning activities involving written language. What is equally significant is what their metalanguage choices reveal about their understanding and application of written language concepts