Relação entre Índice de Massa Corporal e localização anatômica das lesões relacionadas à corrida em corredores amadores / Relationship between Body Mass Index and anatomical location of injuries related to running in amateur runners

Objetivo: Analisar a relação entre Índice de Massa Corporal e localização anatômica das lesões em membros inferiores de corredores amadores avaliados em um serviço privado de ortopedia e fisioterapia.Método: Estudo epidemiológico retrospectivo transversal realizado através da análise de cento e vinte (120) prontuários de corredores que fizeram avaliação de corrida em uma clínica de ortopedia e fisioterapia de Campinas (SP) no período de 2017 a 2018.Resultados: Do total de corredores avaliados, 64% estavam adequados ao peso, 33% tinham sobrepeso e 3% eram obesos. A localização anatômica afetada mais prevalente foi o joelho (47%). No grupo adequado ao peso, com sobrepeso e obeso a lesão mais prevalente foi no joelho (48%, 40% e 100%, respectivamente).Conclusão: Corredores com diferentes Índice de Massa corporal tiveram distribuições distintas quanto ao local da lesão nos membros inferiores. O joelho é o principal local de acometimento de lesões relacionadas à corrida de rua em corredores amadores, independentemente do Índice de Massa Corporal.

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Comparação dos procedimentos de "imprint " e escarificação no diagnóstico da Leishmaniose Tegumentar Americana

Submitted by Anderson Silva ([email protected]) on 2012-09-30T22:59:34Z No. of bitstreams: 1 cintia_x_mello_ipec_pesquisaclinicadi_0002_2011.pdf: 6418751 bytes, checksum: 25c0176616e7ab31ae6bd91f77c3fd69 (MD5)Made available in DSpace on 2012-09-30T22:59:34Z (GMT). No. of bitstreams: 1 cintia_x_mello_ipec_pesquisaclinicadi_0002_2011.pdf: 6418751 bytes, checksum: 25c0176616e7ab31ae6bd91f77c3fd69 (MD5) Previous issue date: 2011Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.A leishmaniose tegumentar americana (LTA) é uma doença infecciosa, causada por parasitas do gênero Leishmania, que apresenta características complexas em diferentes aspectos. O diagnóstico, sempre que possível, deve ser feito com base em evidências epidemiológicas, aspecto clínico e exames laboratoriais. Para pesquisa direta do parasito, são utilizados os procedimentos de escarificação e “imprint”, sendo a escarificação o método mais rápido, de menor custo e de fácil execução. Baseado nas características dos exames diretos para a confirmação dos casos de LTA, o Ministério da Saúde tem incentivado a implantação do procedimento de escarificação em todos os laboratórios centrais de saúde pública, sendo importantes tanto o conhecimento dos parâmetros de acurácia deste método quanto a padronização relacionada a forma de coleta e leitura, para que possa ser aplicado de forma uniformizada em todo o Brasil. Neste estudo, objetivamos avaliar a sensibilidade dos métodos diretos (“imprint”e escarificação), comparados com o teste padrão de referência (cultura). Além disso, buscamos estabelecer critérios de coleta e leitura com fins de uniformização do método para propor sua aplicação em diferentes regiões brasileiras. A população do estudo foi constituída de 110 pacientes com suspeita clínica de LTA que foram atendidos no Laboratório de Vigilância em Leishmanioses (VigiLeish/IPEC/Fiocruz) para avaliação clínica e coleta das amostras. Dentre os 110 pacientes analisados 40 foram confirmados com LTA. O “imprint” foi positivo em 28 pacientes conferindo sensibilidade de 70%, a escarificação realizada em borda externa foi positiva em 17 pacientes e em borda interna em 25 alcançando sensibilidade de 42,5% e 62,5% respectivamente. Além de mais sensível o material obtido da borda interna da lesão apresentou uma maior quantidade de células brancas e menos hemácias facilitando a leitura da lâmina. Os parâmetros de acurácia encontrados para os métodos diretos foram satisfatórios demonstrando que essas metodologias podem ser implantadas em todo o Brasil para o diagnóstico da leishmaniose tegumentar americana.American Tegumentary Leishmaniasis (ATL) is an infectious disease caused by parasites of the genus Leishmania, which has complex characteristics in different aspects. The diagnosis, whenever possible, should be based on epidemiological evidence, clinical aspect and laboratory tests. Imprint and scraping procedures are used for direct detection of the parasite. Scraping is the quickest, low-cost and easy to conduct. Based on the characteristics of direct examination for the confirmation of ATL cases, the Brazilian Ministry of Health has encouraged the implementation of the scraping procedure in all Central public health laboratories. Thus the knowledge of the accuracy parameters of this procedure and the standardization of collection and reading methods are important for its application in a uniform manner throughout Brazil. In this study, we aimed to evaluate the sensitivity of direct methods (imprint and scraping), compared with the reference standard test (culture). Besides, we sought to establish collection and reading criteria with the purpose of standardizing the method to propose its application in different Brazilian regions. The study population comprised 110 patients with clinical suspicion of ATL who were treated at the Laboratory of Leishmaniasis Surveillance (VigiLeish/IPEC/Fiocruz) for clinical evaluation and sample collection. Among the 110 patients studied, 40 were confirmed with ATL. The imprint was positive in 28 patients granting sensitivity of 70%, scraping conducted in the outer edge was positive in 17 patients and in the inner edge in 25, reaching sensitivity of 42.5% and 62.5% respectively. The material obtained from the inner edge of the lesion was more sensitive and presented a larger amount of white cells and lesser red cells, favoring slide reading. Accuracy parameters found for the direct methods were satisfactory showing that they may be implemented in all Brazilian regions for the diagnosis of American tegumentary leishmaniasis

Estruturas leveduriformes de Sporothrix schenckii podem gerar confusão no diagnóstico parasitológico direto da leishmaniose tegumentar americana?

Submitted by Repositório Arca ([email protected]) on 2019-04-24T16:40:55Z No. of bitstreams: 1 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Approved for entry into archive by Janaína Nascimento ([email protected]) on 2019-11-22T13:00:02Z (GMT) No. of bitstreams: 2 ve_Mello_Cintia_etal_INI_2011_eng.pdf: 1111580 bytes, checksum: 363e8f6e6a17312743698de60ac20b0d (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Made available in DSpace on 2019-11-22T13:00:02Z (GMT). No. of bitstreams: 2 ve_Mello_Cintia_etal_INI_2011_eng.pdf: 1111580 bytes, checksum: 363e8f6e6a17312743698de60ac20b0d (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratório em Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratório em Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Laboratório em Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil

Avaliação do efeito dos antimicrobianos benzilpenicilina estreptomicina e flucitosina, no crescimento “in vitro” de Leishmania braziliensis

Submitted by Alexandre Sousa ([email protected]) on 2015-11-19T17:22:17Z No. of bitstreams: 1 analytica_49_72-78.pdf: 400944 bytes, checksum: 64dc82f656c9776d2465d845cb688392 (MD5)Approved for entry into archive by Alexandre Sousa ([email protected]) on 2015-11-19T17:31:02Z (GMT) No. of bitstreams: 1 analytica_49_72-78.pdf: 400944 bytes, checksum: 64dc82f656c9776d2465d845cb688392 (MD5)Made available in DSpace on 2015-11-19T17:31:02Z (GMT). No. of bitstreams: 1 analytica_49_72-78.pdf: 400944 bytes, checksum: 64dc82f656c9776d2465d845cb688392 (MD5) Previous issue date: 2010Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Comissão do Programa de Ensaio de Proficiência de Produtos Sujeitos ao Regime de Vigilância Sanitária. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Química. Rio de Janeiro, RJ, Brasil.As leishmanioses constituem um grupo de doenças infecciosas causadas por protozoários do gênero Leishmania. No diagnóstico laboratorial da Leishmaniose o isolamento em cultura é considerado padrão-ouro, entretanto tem como inconveniente a possibilidade de contaminação secundária por bactérias e fungos que inviabilizam o exame. A fim de minimizar a contaminação são utilizados antibióticos como benzilpenicilina e estreptomicina e antifúngicos como flucitosina. Concentrações ideais destes antimicrobianos, para que o isolamento do protozoário não seja prejudicado, necessitam ser estabelecidas. Neste trabalho estudou-se o efeito de diferentes concentrações dos antibióticos (benzilpenicilina e estreptomicina) e do antifúngico (flucitosina) sobre o crescimento de Leishmania braziliensis “in vitro”. Os resultados demonstraram que as concentrações de 1000 e 500 U/mL de benzilpenicilina e, 1000 e 500 μg/mL de estreptomicina e flucitosina, exerceram inibição significativa do crescimento do protozoário, indicando que essas substâncias devem ser utilizadas com certa cautela na rotina do diagnóstico das leishmaniosesThe leishmaniases are a group of diseases caused by protozoa of the genus Leishmania. In the laboratory diagnosis of leishmaniasisisolation in culture is considered the gold standard, but has the drawback the possibility of secondary contamination by bacteria and fungi that prevent the examination. To minimize contamination are used as antibiotics benzylpenicillin and streptomycin and flucytosine as antifungal agents, however it is necessary to seek optimal concentrations for the isolation of the parasite is not jeopardized. We studied the effect of different concentrations of antibiotics (Penicillin and streptomycin) and antifungal (flucitosine) on the growth of Leishmania braziliensisin vitro. The results showed that concentrations of 1000 and 500 µg/mL flucitosine and streptomycin and 1000 and 500 U/mL penicillin showed significant inhibition of parasite growth, indicating that these substances should be used with some caution in the routine diagnosis of leishmaniasis

Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro

Submitted by Rodrigo Senorans ([email protected]) on 2015-05-22T16:42:34Z No. of bitstreams: 1 Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro.pdf: 692413 bytes, checksum: d91184a04249d6aa693f1a167841a542 (MD5)Approved for entry into archive by Anderson Silva ([email protected]) on 2015-05-25T11:53:18Z (GMT) No. of bitstreams: 1 Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro.pdf: 692413 bytes, checksum: d91184a04249d6aa693f1a167841a542 (MD5)Approved for entry into archive by Anderson Silva ([email protected]) on 2015-05-25T11:53:25Z (GMT) No. of bitstreams: 1 Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro.pdf: 692413 bytes, checksum: d91184a04249d6aa693f1a167841a542 (MD5)Made available in DSpace on 2015-05-25T15:45:42Z (GMT). No. of bitstreams: 1 Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro.pdf: 692413 bytes, checksum: d91184a04249d6aa693f1a167841a542 (MD5) Previous issue date: 2014Instituto Nacional de Infectologia Evandro Chagas/Fundação Oswaldo Cruz (FIOCRUZ) e Prefeitura Municipal de Barra Mansa.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Dermatozoonoses. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Vigilância em Leishmanioses. Rio de Janeiro, RJ, BrasilIntroduction: In Brazil, visceral leishmaniasis (VL) has spread to various regions. This study reports canine cases of VL in Barra Mansa, where human VL cases were recently reported. Methods: Using the human index case, a canine survey was performed by dual-path platform immunochromatography and enzyme-linked immunosorbent assay. Seropositive animals were euthanized. Cultures were collected to detect Leishmania parasites. Results: Serological tests detected 141 canine VL cases, and Leishmania chagasi were isolated from 82.2% animals. Conclusions: Leishmania chagasi is in circulation in Barra Mansa. This study broadens information on the parasite’s distribution in the State of Rio de Janeiro