230 research outputs found

    Characterization of CMOS Spiral Inductors

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    In this work "full-wave" simulations of integrated inductors are presented and compared with measurements of fabricated CMOS chips. The good agreement between measurements and simulations demonstrates the accuracy of the tool, which is, hence, a cheaper alternative to experimental characterization. Furthermore, the proposed approach may give precious hints for performance improvements, by making internal device fields and currents available for the VLSI designer and providing compact, most effective, equivalent models

    Haplotype association analysis of meat quality traits at the bovine PRKAG3 locus

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    The current study presents the results of a preliminary haplotype association analysis at the bovine PRKAG3 locus with meat quality traits in the Chianina breed. No significant association was shown between haploid haplotypes (or diplotypes) and phenotypical traits after applying a Bonferroni correction for multiple comparison. Nonetheless, data from Longissimus dorsi muscle suggest the presence of a statistically non-significant trend toward an influence of the PRKAG3 haploid haplotypes on meat colour (a*) and water holding capacity (M/T) traits, as confirmed also by diplotype-based association analysis. A less clear set of results was observed for the Triceps brachii and Semitendinosus muscles

    Health, not weight loss, focused programmes versus conventional weight loss programmes for cardiovascular risk factors:A systematic review and meta-analysis

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    © 2019 The Authors. Published by BMC. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website:Background: Obesity is a cardiovascular disease risk factor. Conventional weight loss (CWL) programmes focus on weight loss, however 'health, not weight loss, focused' (HNWL) programmes concentrate on improved health and well-being, irrespective of weight loss. What are the differences in CVD risk outcomes between these programmes? Aim: To conduct a systematic review and meta-analysis to compare the effects of HNWL with CWL programmes on cardiovascular disease risk factors. Methods: We searched CENTRAL, MEDLINE, EMBASE, PsycINFO, CINAHL, ASSIA, clinical trial registers, commercial websites and reference lists for randomised controlled trials comparing the two programmes (initially searched up to August 2015 and searched updated to 5 April 2019). We used the Mantel-Haneszel fixed-effect model to pool results. Sub-group and sensitivity analyses that accounted for variations in length of follow-up, enhanced programmes and risk of bias dealt with heterogeneity. Results: Eight randomised controlled trials of 20,242 potential studies were included. Improvements in total cholesterol-HDL ratio (mean difference-0.21 mmol/L, 95% confidence interval [-3.91, 3.50]) and weight loss (-0.28 kg [-2.00, 1.44]) favoured HNWL compared to CWL programmes in the long term (53-104 week follow-up), whereas improvements in systolic (-1.14 mmHg, [-5.84, 3.56]) and diastolic (-0.15 mmHg, [-3.64, 3.34]) blood pressure favoured CWL programmes. These differences did not reach statistical significance. Statistically significant improvements in body satisfaction (-4.30 [-8.32,-0.28]) and restrained eating behaviour (-4.30 [-6.77,-1.83]) favoured HNWL over CWL programmes. Conclusions: We found no long-term significant differences in improved CVD risk factors; however, body satisfaction and restrained eating behaviour improved more with HNWL compared to CWL programmes. Yet firm conclusions cannot be drawn from small studies with high losses to follow-up and data sometimes arising from a single small study.Published versio

    Tuning Reactivity and Electronic Properties through Ligand Reorganization within a Cerium Heterobimetallic Framework

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    Interruption of scheduled, automatic feeding and reduction of excess energy intake in toddlers

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    Mario Ciampolini,1 J Thomas Brenna,2 Valerio Giannellini,3 Stefania Bini11Preventive Gastroenterology Unit, Department of Paediatrics, Università di Firenze, Florence, Italy; 2Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA; 3Department of Pharmaceutical Sciences, Università di Firenze, Florence, ItalyBackground: Childhood obesity due to the consumption of excess calories is a severe problem in developed countries. In a previous investigation on toddlers, hospital laboratory measurements showed an association of food-demand behavior with constant lower blood glucose before meals than for scheduled meals. We hypothesize that maternal scheduling of meals for toddlers results in excess energy intake compared to feeding only on demand (previously “on request”).Objective: We tested the cross-sectional null hypothesis of no difference in energy intake between scheduled (automatic) and demanded meals (administered after evaluation) in 24 mother–toddler (21 months old at entry) pairs with chronic, nonspecific diarrhea presenting at a clinic. We tested the same hypothesis in a subset of 14 toddlers by measuring the resting (sleeping) metabolic rate 4 hours after lunch, as well as the total daily energy expenditure (TEE) in 10 toddlers.Methods: We trained mothers to recognize meal demands (as in the previous investigation) and to provide food in response, but required no blood glucose measurements before meals. Energy intake was assessed by a 10-day food diary, resting metabolic rate (RMR) by respiratory analyses (indirect calorimetry) in 14 toddlers, and TEE by doubly labeled water in 10 toddlers. Their blood parameters, anthropometry, and number of days with diarrhea were assessed before training and 50 days after training.Results: RMR decreased from 58.6 ± 7.8 to 49.0 ± 9.1 kcal/kg/d (P < 0.001) and TEE decreased from 80.1 ± 6.9 to 67.8 ± 10.0 kcal/kg/d (P < 0.001). Energy intake decreased from 85.7 ± 15.3 to 70.3 ± 15.8 kcal/kg/d (P < 0.001). The height Z-score increased significantly, while weight growth was normal. Toddlers entering the study over the median RMR decreased their RMR significantly more than those below the median RMR (P < 0.01).Conclusion: Scheduled meal suspension induces meal demand frequency to increase. Demanded meals are associated with significantly lower energy intake, RMR, and TEE than scheduled meals. Feeding on demand may be an effective skill in a strategy for reducing excess energy intake in the long term and in regulating body weight in toddlers and children.Keywords: hunger, intake, meals, energy, homeostasis, blood glucose, meal pattern, intake habit, overweight, balance, chronic diarrhe

    Electrical Appliances Networking: An Ultra-Low Cost Solution Based on Power-Line Communication

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    This paper discusses a novel communication system, devoted to networking of electrical appliances. The proposed solution relies on a "proxy" approach: bidirectional point-topoint communication (called ULP: Ultra-Low cost Power-line) is established on the power-supply wire, between the appliance and the outlet. Here a transceiver embeds both network management functions and ULP communication, acting as a proxy between the appliance and the home network. The proposed approach provides several advantages: i) communication costs at the appliance side are kept at a minimum and, ii) appliance hardware and software are virtually independent from the actual networking protocol, managed by the external proxy device. In order to make the application of ULP communication straightforward, transceiver physical layer have been implemented in a dedicated peripheral for a general-purpose microcontroller. Test of the peripheral has been carried out by exploiting a development tool based on a μC-FPGA mixed architecture, where programmable device is directly connected to the microprocessor bus. This solution closely emulates the perspective microcontroller architecture, and allows for extensive testing of the device under realistic operating conditions. ULP communication has been fully characterized, attaining a BER figure well below 10-
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