93 research outputs found
Forest Biodiversity Assessment in Peruvian Andean Montane Cloud Forest
Cloud forests are unusual and fragile habitats, being one of the least studied and least understood ecosystems. The tropical Andean dominion is considered one of the most significant places in the world as rega rds biological diversity, with a very high level of endemism. The biodiversity was analysed in an isolated remnant area of a tropical montane cloud forest known as the ?Bosque de Neblina de Cuyas?, in the North of the Peruvian Andean range. Composition, structure and dead wood were measured or estimated. The values obtained were compared with other cloud forests. The study revealed a high level of forest biodiversity, although the level of biodiversity differs from one area to another: in the inner areas, where human pressure is almost inexistent, the biodiversity values increase. The high species richness and the low dominance among species bear testimony to this montane cloud forest as a real enclave of biodiversity
Representational predicaments for employees: Their impact on perceptions of supervisors\u27 individualized consideration and on employee job satisfaction
A representational predicament for a subordinate vis-à -vis his or her immediate superior involves perceptual incongruence with the superior about the subordinate\u27s work or work context, with unfavourable implications for the employee. An instrument to measure the incidence of two types of representational predicament, being neglected and negative slanting, was developed and then validated through an initial survey of 327 employees. A subsequent substantive survey with a fresh sample of 330 employees largely supported a conceptual model linking being neglected and negative slanting to perceptions of low individualized consideration by superiors and to low overall job satisfaction. The respondents in both surveys were all Hong Kong Chinese. Two case examples drawn from qualitative interviews illustrate and support the conceptual model. Based on the research findings, we recommend some practical exercises to use in training interventions with leaders and subordinates. © 2013 Copyright Taylor and Francis Group, LLC
Meta-analysis of type 2 Diabetes in African Americans Consortium
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 Ă 10(-94)<P<5 Ă 10(-8), odds ratio (OR)â = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 Ă 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe
UrolitĂase: estudo comparativo em bovinos GuzerĂĄ oriundos de propriedades com e sem o problema
Diversos fatores podem contribuir para a formação de cĂĄlculos urinĂĄrios, dentre estes, o desequilĂbrio nutricional e a dureza da ĂĄgua consumida pelos ruminantes. O objetivo deste estudo foi identificar as caracterĂsticas de propriedades que predispĂ”em Ă urolitĂase, atravĂ©s da avaliação da ĂĄgua, da dieta e determinaçÔes sĂ©ricas e urinĂĄrias de cĂĄlcio, fĂłsforo, magnĂ©sio, cloretos, sĂłdio, potĂĄssio, cĂĄlculo da excreção fracionada (EF) dos eletrĂłlitos, e da creatinina, proteĂna total, albumina e globulinas sĂ©ricas. Foram colhidas amostras de sangue e urina de bovinos, GuzerĂĄ, criados semi intensivamente, distribuĂdos por dois grupos. O primeiro denominado grupo urolitĂase (Gu), composto de animais com histĂłrico, sinais clĂnicos e confirmação ultrassonogrĂĄfica que apresentavam urolitĂase; o segundo: grupo controle (Gc), sem histĂłrico, nem sintomas da doença. Os bovinos do grupo urolitĂase consumiam ĂĄgua com dureza total na concentração de 166,0mg CaCO3/L. A dieta dos animais do Gu apresentava maior concentração de fĂłsforo e relação Ca:P inadequada. Os teores de fĂłsforo sĂ©rico e urinĂĄrio dos animais do Gu foram maiores do que os do Gc, assim como a concentração sĂ©rica de magnĂ©sio (p0,05), mas houve diminuição significativa nas EFs de magnĂ©sio, cloretos e de potĂĄssio do grupo urolitĂase (p<0,05). A uniĂŁo destes fatores contribuiu para a ocorrĂȘncia da urolitĂase, sendo dureza total da ĂĄgua e a alta concentração de fĂłsforo na dieta os principais fatores na gĂȘnese dos cĂĄlculos em bovinos
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Track A Basic Science
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd
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