42 research outputs found
Colistin non-susceptible Pseudomonas aeruginosa ST654 with blaNDM-1 arrives in North America
This study describes 3 different blaNDM-1 genetic platforms in 3 different species obtained from
the same patient who was directly transferred to an institution in Calgary, Canada, following a
prolonged hospital stay in India. The blaNDM-1 in the Escherichia coli was located on a 176kb
IncA/C plasmid contained within an ISCR1 region. The blaNDM-1 in the Providencia rettgeri was
located on a 117kb IncT plasmid contained within Tn3000, while the blaNDM-1 in Pseudomonas
aeruginosa was located on the chromosome within an ISCR3 region. This report highlights the
plasticity of the genetic regions and environments associated with blaNDM-1. To the best of our
knowledge, this is the first report of P. aeruginosa with blaNDM-1 identified in North America and
the first report of blaOXA-181in P. rettgeri. The P. aeruginosa belonged to the international high
risk clone ST654 and was non-susceptible to colistin. This case emphasizes the need for
appropriate infection prevention and control measures and vigilant screening for carbapenem
resistant Gram negative bacteria in patients with a history of travel to endemic areas, such as the
Indian subcontinent.In part by a research grant from the Calgary Laboratory Services (#10009392).http://aac.asm.org2016-09-30hb201
Effects of sea level rise on economy of the United States
We report the first ex post study of the economic impact of sea level rise. We apply two econometric approaches to estimate the past effects of sea level rise on the economy of the USA, viz. Barro type growth regressions adjusted for spatial patterns and a matching estimator. Unit of analysis is 3063 counties of the USA. We fit growth regressions for 13 time periods and we estimated numerous varieties and robustness tests for both growth regressions and matching estimator. Although there is some evidence that sea level rise has a positive effect on economic growth, in most specifications the estimated effects are insignificant. We therefore conclude that there is no stable, significant effect of sea level rise on economic growth. This finding contradicts previous ex ante studies
Design and construction of the MicroBooNE detector
This paper describes the design and construction of the MicroBooNE liquid
argon time projection chamber and associated systems. MicroBooNE is the first
phase of the Short Baseline Neutrino program, located at Fermilab, and will
utilize the capabilities of liquid argon detectors to examine a rich assortment
of physics topics. In this document details of design specifications, assembly
procedures, and acceptance tests are reported
Long-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report Volume 2: The Physics Program for DUNE at LBNF
The Physics Program for the Deep Underground Neutrino Experiment (DUNE) at the Fermilab Long-Baseline Neutrino Facility (LBNF) is described