Decoherence induced CPT violation and entangled neutral mesons

We discuss two classes of semi-microscopic theoretical models of stochastic space-time foam in quantum gravity and the associated effects on entangled states of neutral mesons, signalling an intrinsic breakdown of CPT invariance. One class of models deals with a specific model of foam, initially constructed in the context of non-critical (Liouville) string theory, but viewed here in the more general context of effective quantum-gravity models. The relevant Hamiltonian perturbation, describing the interaction of the meson with the foam medium, consists of off-diagonal stochastic metric fluctuations, connecting distinct mass eigenstates (or the appropriate generalisation thereof in the case of K-mesons), and it is proportional to the relevant momentum transfer (along the direction of motion of the meson pair). There are two kinds of CPT-violating effects in this case, which can be experimentally disentangled: one (termed ``omega-effect'') is associated with the failure of the indistinguishability between the neutral meson and its antiparticle, and affects certain symmetry properties of the initial state of the two-meson system; the second effect is generated by the time evolution of the system in the medium of the space-time foam, and can result in time-dependent contributions of the $omega-effect type in the time profile of the two meson state. Estimates of both effects are given, which show that, at least in certain models, such effects are not far from the sensitivity of experimental facilities available currently or in the near future. The other class of quantum gravity models involves a medium of gravitational fluctuations which behaves like a ``thermal bath''. In this model both of the above-mentioned intrinsic CPT violation effects are not valid.Comment: 16 pages revtex, no figure

Comparing Subsurface Trespass Jurisprudence—Geophysical Surveying and Hydraulic Fracturing

This article examines the basics of two types of subsurface activity— geophysical prospecting (and the myriad of different surveys that comprise same) and hydraulic fracturing (or “fracing” sometimes herein)—describing the purpose of both, comparing the physical science background, field activities necessary, and data gathered in both, and analysis of the motivations of the parties conducting the activities. The article also contains an examination of selected germane subsurface trespass jurisprudence from New Mexico, Texas, and beyond. The article ends with thoughts and about what ought to be the state of subsurface trespass jurisprudence related to geophysical surveying and fracing and whether any uniformity exists between the two that could be applied to other activities. Ultimately, this article concludes that regulated fracing, which is currently less controllable than similar subsurface activities such as seismic reflection surveys, should not be liable for common law trespass claims in order to strengthen domestic energy security, prevent waste, and promote responsible self-development by mineral owners

Slip complexity in a crustal plane model of an earthquake fault

We study numerically the behavior of a two-dimensional elastic plate (a crustal plane) that terminates along one of its edges at a fault boundary. Slip-weakening friction at the boundary, inertial dynamics in the bulk, and uniform slow loading via elastic coupling to a substrate combine to produce a complex, deterministically chaotic sequence of slipping events. We observe a power-law distribution of small events and an excess of large events. For the small events, the moments scale with rupture length in a manner that is consistent with seismological observations. For the large events, rupture occurs in the form of narrow propagating pulses

Designing biodegradable alternatives to commodity polymers

The development and widespread adoption of commodity polymers changed societal landscapes on a global scale. Without the everyday materials used in packaging, textiles, construction and medicine, our lives would be unrecognisable. Through decades of use, however, the environmental impact of waste plastics has become grimly apparent, leading to sustained pressure from environmentalists, consumers and scientists to deliver replacement materials. The need to reduce the environmental impact of commodity polymers is beyond question, yet the reality of replacing these ubiquitous materials with sustainable alternatives is complex. In this tutorial review, we will explore the concepts of sustainable design and biodegradability, as applied to the design of synthetic polymers intended for use at scale. We will provide an overview of the potential biodegradation pathways available to polymers in different environments, and highlight the importance of considering these pathways when designing new materials. We will identify gaps in our collective understanding of the production, use and fate of biodegradable polymers: from identifying appropriate feedstock materials, to considering changes needed to production and recycling practices, and to improving our understanding of the environmental fate of the materials we produce. We will discuss the current standard methods for the determination of biodegradability, where lengthy experimental timescales often frustrate the development of new materials, and highlight the need to develop better tools and models to assess the degradation rate of polymers in different environments

Particle dynamics of a cartoon dune

The spatio-temporal evolution of a downsized model for a desert dune is observed experimentally in a narrow water flow channel. A particle tracking method reveals that the migration speed of the model dune is one order of magnitude smaller than that of individual grains. In particular, the erosion rate consists of comparable contributions from creeping (low energy) and saltating (high energy) particles. The saltation flow rate is slightly larger, whereas the number of saltating particles is one order of magnitude lower than that of the creeping ones. The velocity field of the saltating particles is comparable to the velocity field of the driving fluid. It can be observed that the spatial profile of the shear stress reaches its maximum value upstream of the crest, while its minimum lies at the downstream foot of the dune. The particle tracking method reveals that the deposition of entrained particles occurs primarily in the region between these two extrema of the shear stress. Moreover, it is demonstrated that the initial triangular heap evolves to a steady state with constant mass, shape, velocity, and packing fraction after one turnover time has elapsed. Within that time the mean distance between particles initially in contact reaches a value of approximately one quarter of the dune basis length

Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART.

BackgroundSystemic inflammation persists in chronic HIV infection and is associated with increased rates of non-AIDS events such as cardiovascular and liver disease. Increased gut permeability and systemic exposure to microbial products are key drivers of this inflammation. Serum-derived bovine immunoglobulin/protein isolate (SBI) supports gut healing in other conditions such as inflammatory bowel disease.MethodsIn this randomized, double-blind study, participants receiving suppressive antiretroviral therapy (ART) with chronic diarrhea received placebo or SBI at 2.5 g BID or 5 g BID for 4 weeks, followed by a 20-week placebo-free extension phase with SBI at either 2.5 or 5 g BID. Intestinal fatty acid binding protein (I-FABP), zonulin, flagellin, lipopolysaccharide (LPS) and LPS-binding protein, and inflammatory markers were measured by ELISA or multiplex assays. Non-parametric tests were used for analysis.ResultsOne hundred three participants completed the study. By week 24 SBI significantly decreased circulating levels of I-FABP (-0.35 ng/μL, P=0.002) and zonulin (-4.90 ng/μL, P=0.003), suggesting improvement in gut damage, and interleukin-6 (IL-6) (-0.40 pg/μL, P=0.002), reflecting improvement in systemic inflammation. In participants with the lowest quartile of CD4+ T-cell counts at baseline (189-418 cells/μL), CD4+ T-cell counts increased significantly (26 cells/μL; P=0.002).ConclusionsOral SBI may decrease inflammation and warrants further exploration as a potential strategy to improve gut integrity and decrease systemic inflammation among persons receiving prolonged suppressive ART

MI5 and the Cold War in South-East Asia: Examining the Performance of Security Intelligence Far East (SIFE), 1946-1963

From 1946–1963, MI5 operated a South-East Asian regional headquarters in Singapore: Security Intelligence Far East (SIFE). This article responds to growing interest in theatre-level intelligence organisation and the importance of intelligence to Britain’s Cold War and decolonisation by examining the performance of SIFE. On the organisational level, SIFE was strongest when it remained wedded to its charter functions and closely adhered to the priorities of its principal consumer: the Commissioner-General for South-East Asia. Its assessments were influential in shaping decision-makers’ understandings of key regional developments, although this did not always translate into public policy. Lastly, SIFE enjoyed success in developing lasting liaison relationships to cement British influence, but failed to utilise these to improve its intake of raw intelligence