'I try to forget about the dementia': Realising the resilience of the person ageing with dementia in social work practice

This thesis considers whether the concept of resilience is applicable to people ageing with dementia; and, if so, what the implications are for social work practice. It begins with an exploration of the literature on dementia, resilience and social work. Using a symbolic interactionist approach it then details how the interactions of people with dementia and their social workers can potentially influence the realisation of resilience in practice. I collected data over a two year period. During this period six dyads comprising a person with dementia and social worker provided rich verbal accounts of their respective experiences. Using narrative analysis the stories of each person with dementia were explored to reveal threats to identity and possible resilience strategies. A resilience lens was applied to the verbal accounts of social workers in order to reveal opportunities and challenges to using resilience in practice. The findings indicate that identity continues to be of importance to people who are ageing with dementia. The preservation of identity could therefore be re-framed as the outcome of a resilience process. Each person could potentially acquire resources over their life which could help to mitigate threats to identity. This is referred to as the resilience reserve. This thesis details the potential domains of such a reserve. Further, it contains details of possible resilience strategies that a person with dementia might employ within stories of self. These strategies are placed within the context of protective and vulnerability factors in order that a resilience framework can emerge. This thesis argues for a re-framing of theories of what social work is. This, combined with a definition of resilience, and the development of a resilience practice framework could promote and realise the resilience of the person ageing with dementia

Corpo em Nietzsche: uma leitura da II dissertação da genealogia da moral

This paper aims to investigate the notion of body at the thought of German philosopher Friedrich Nietzsche, specifically from a reading of some themes in the second Dissertation of Genealogy of Morals, basic to mobilize such a notion. Among the listed issues are the role of consciousness, memory, forgetfulness, guilt and the criminal figure, starting from the reading that we propose, can be extremely important to think about the body Nietzsche.O presente artigo tem por objetivo investigar a noção de corpo no pensamento do filósofo alemão Friedrich Nietzsche, mais especificamente a partir de uma leitura de alguns temas presentes na II Dissertação da Genealogia da Moral, basilares para se mobilizar tal noção. Dentre as questões elencadas encontram-se o papel da consciência, a memória, o esquecimento, o sentimento de culpa e a figura do criminoso que, partindo-se da leitura a que nos propomos, podem ser de fundamental importância para se pensar o corpo em Nietzsche

Developing a Community-Designed Healthy Urban Food System

Learning About Food in Urban Communities is a comprehensive guide with Extension resources for Food Production, Food & Business, Food & Family, and Food & Community. This publication emerged as part of a 2-year community-planning project. An interdisciplinary OSU team worked with the Weinland Park community, in the central Ohio University District, to explore how food could be a catalyst for urban neighborhood development

Protein Ontology: A controlled structured network of protein entities

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments

Trade-offs in marine protection : Multi-species interactions within a community-led temperate marine reserve

This study investigated the effects of a community-led temperate marine reserve in Lamlash Bay, Firth of Clyde, Scotland, on commercially important populations of European lobster (Homarus gammarus), brown crab (Cancer pagurus), and velvet swimming crabs (Necora puber). Potting surveys conducted over 4 years revealed significantly higher catch per unit effort (cpue 109% greater), weight per unit effort (wpue 189% greater), and carapace length (10-15 mm greater) in lobsters within the reserve compared with control sites. However, likely due to low levels of recruitment and increased fishing effort outside the reserve, lobster catches decreased in all areas during the final 2 years. Nevertheless, catch rates remained higher within the reserve across all years, suggesting the reserve buffered these wider declines. Additionally, lobster cpue and wpue declined with increasing distance from the boundaries of the marine reserve, a trend which tag-recapture data suggested were due to spillover. Catches of berried lobster were also twice as high within the reserve than outside, and the mean potential reproductive output per female was 22.1% greater. It was originally thought that higher densities of lobster within the reserve might lead to greater levels of aggression and physical damage. However, damage levels were solely related to body size, as large lobsters >110 mm had sustained over 218% more damage than smaller individuals. Interestingly, catches of adult lobsters were inversely correlated with those of juvenile lobsters, brown crabs, and velvet crabs, which may be evidence of competitive displacement and/or predation. Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, and highlight the importance of investigating multispecies interactions, as the recovery of some species can have knock-on effects on others

Comparison of computationally- and manually-assigned Gene Ontology annotations to improve functional characterization of gene products.

The Gene Ontology (GO) describes molecular functions, biological processes, and cellular components of gene products using controlled-vocabulary terms that are related to each other in a structure that facilitates computing on GO annotations within and across species. Experimentally-based GO annotations that are manually curated from the literature are often used to predict the functions of related uncharacterized proteins. The accuracy of such annotations is thus critically important, particularly for a well-studied model organism such as _Saccharomyces cerevisiae_ which is frequently used as the source of the experimental data. 

Comparison of experimentally-based annotations with those predicted by computational methods for the same gene products may reveal inaccuracies in curation of the experimental data, and could additionally be used to evaluate and improve the computational methods. We will present the results of an analysis at SGD that identified four major reasons for discrepancies between the two kinds of annotation. Some discrepancies revealed cases in which human error led to errors or omissions in the manual curation, prompting prioritization for review and correction. In another category, the computational annotations were not supported or were refuted by the literature, thereby suggesting ways in which the accuracy of the prediction methods could be improved. Yet another type of discrepancy resulted from issues with the GO structure, such as missing parentage for certain terms, leading to reexamination and improvement of the ontology. Finally, some discrepancies arose because the computational predictions were entirely novel, and no relevant experimental evidence was available. These cases highlight potential interesting new avenues for experimentation.
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