311 research outputs found

    Developing Stochastic Models for Spatial Inference: Bacterial Chemotaxis

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    Background: Biological systems are inherently inhomogeneous and spatial effects play a significant role in processes such as pattern formation. At the cellular level proteins are often localised either through static attachment or via a dynamic equilibrium. As well as spatial heterogeneity many cellular processes exhibit stochastic fluctuations and so to make inferences about the location of molecules there is a need for spatial stochastic models. A test case for spatial models has been bacterial chemotaxis which has been studied extensively as a model of signal transduction. Results: By creating specific models of a cellular system that incorporate the spatial distributions of molecules we have shown how the fit between simulated and experimental data can be used to make inferences about localisation, in the case of bacterial chemotaxis. This method allows the robust comparison of different spatial models through alternative model parameterisations. Conclusions: By using detailed statistical analysis we can reliably infer the parameters for the spatial models, and also to evaluate alternative models. The statistical methods employed in this case are particularly powerful as they reduce the need for a large number of simulation replicates. The technique is also particularly useful when only limited molecular level data is available or where molecular data is not quantitative

    Superconductivity in the C32 Intermetallic Compounds AAl(2-x)Si(x), with A=Ca and Sr, and 0.6<x<1.2

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    The intermetallic compounds AAl2-xSix, where A = Ca, Sr or Ba, crystallize in the C32 structure, same as the recently discovered MgB2 with a high superconducting transition temperature of 39 K. For x = 1, superconductivity has been observed in AAlSi with A = Ca and Sr, but not with A = Ba. The transition temperatures are 7.8 and 5.1 K, respectively for CaAlSi and SrAlSi. The CaAl2-xSix compound system display a Tc-peak at x = 1, a possible x-induced electronic transition at x ~ 0.75 and a possible miscibility gap near x ~ 1.1 which results in a very broad superconducting transition. The Seebeck coefficients of AAlSi indicate that their carriers are predominantly electrons in nature, in contrast to the holes in MgB2.Comment: 10 pages, 6 figure

    Effect of Quantum Fluctuations in an Ising System on Small-World Networks

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    We study quantum Ising spins placed on small-world networks. A simple model is considered in which the coupling between any given pair of spins is a nonzero constant if they are linked in the small-world network and zero otherwise. By applying a transverse magnetic field, we have investigated the effect of quantum fluctuations. Our numerical analysis shows that the quantum fluctuations do not alter the universality class at the ferromagnetic phase transition, which is of the mean-field type. The transition temperature is reduced by the quantum fluctuations and eventually vanishes at the critical transverse field Δc\Delta_c. With increasing rewiring probability, Δc\Delta_c is shown to be enhanced.Comment: 5 pages, 5 figure

    BKB\to K Transition Form Factor up to O(1/mb2){\cal O}(1/m^2_b) within the kTk_T Factorization Approach

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    In the paper, we apply the kTk_T factorization approach to deal with the BKB\to K transition form factor F+,0BK(q2)F^{B\to K}_{+,0}(q^2) in the large recoil regions. The B-meson wave functions ΨB\Psi_B and ΨˉB\bar\Psi_B that include the three-particle Fock states' contributions are adopted to give a consistent PQCD analysis of the form factor up to O(1/mb2){\cal O} (1/m^2_b). It has been found that both the wave functions ΨB\Psi_B and ΨˉB\bar\Psi_B can give sizable contributions to the form factor and should be kept for a better understanding of the BB meson decays. Then the contributions from different twist structures of the kaon wavefunction are discussed, including the SUf(3)SU_f(3)-breaking effects. A sizable contribution from the twist-3 wave function Ψp\Psi_p is found, whose model dependence is discussed by taking two group of parameters that are determined by different distribution amplitude moments obtained in the literature. It is also shown that F+,0BK(0)=0.30±0.04F^{B\to K}_{+,0}(0)=0.30\pm0.04 and [F+,0BK(0)/F+,0Bπ(0)]=1.13±0.02[F^{B\to K}_{+,0}(0)/F^{B\to \pi}_{+,0}(0)]=1.13\pm0.02, which are more reasonable and consistent with the light-cone sum rule results in the large recoil regions.Comment: 22 pages and 6 figure

    The transition form factors for semi-leptonic weak decays of J/ψJ/\psi in QCD sum rules

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    Within the Standard Model, we investigate the semi-leptonic weak decays of J/ψJ/\psi. The various form factors of J/ψJ/\psi transiting to a single charmed meson (D(d,s)()D^{(*)}_{(d,s)}) are studied in the framework of the QCD sum rules. These form factors fully determine the rates of the weak semi-leptonic decays of J/ψJ/\psi and provide valuable information about the non-perturbative QCD effects. Our results indicate that the decay rate of the semi-leptonic weak decay mode J/ψDs()+e++νeJ/\psi \to D^{(*)-}_{s}+e^{+}+\nu_{e} is at order of 101010^{-10}.Comment: 28 pages, 6 figures, revised version to be published in Eur.Phys.J.

    A Study of Cosmic Ray Secondaries Induced by the Mir Space Station Using AMS-01

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    The Alpha Magnetic Spectrometer (AMS-02) is a high energy particle physics experiment that will study cosmic rays in the 100MeV\sim 100 \mathrm{MeV} to 1TeV1 \mathrm{TeV} range and will be installed on the International Space Station (ISS) for at least 3 years. A first version of AMS-02, AMS-01, flew aboard the space shuttle \emph{Discovery} from June 2 to June 12, 1998, and collected 10810^8 cosmic ray triggers. Part of the \emph{Mir} space station was within the AMS-01 field of view during the four day \emph{Mir} docking phase of this flight. We have reconstructed an image of this part of the \emph{Mir} space station using secondary π\pi^- and μ\mu^- emissions from primary cosmic rays interacting with \emph{Mir}. This is the first time this reconstruction was performed in AMS-01, and it is important for understanding potential backgrounds during the 3 year AMS-02 mission.Comment: To be submitted to NIM B Added material requested by referee. Minor stylistic and grammer change

    Evidence for CP-Violating Asymmetries in B0->pi+pi- Decays and Constraints on the CKM Angle phi2

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    We present an improved measurement of CP-violating asymmetries in B0 -> pi+ pi- decays based on a 78 fb^-1 data sample collected at the Y(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We reconstruct one neutral B meson as a B0 -> pi+ pi- CP eigenstate and identify the flavor of the accompanying B meson from inclusive properties of its decay products. We apply an unbinned maximum likelihood fit to the distribution of the time intervals between the two B meson decay points. The fit yields the CP-violating asymmetry amplitudes Apipi = +0.77+/-0.27(stat)+/-0.08(syst) and Spipi = -1.23+/-0.41(stat)+0.08/-0.07(syst), where the statistical uncertainties are determined from Monte Carlo pseudo-experiments. We obtain confidence intervals for CP-violating asymmetry parameters Apipi and Spipi based on a frequentist approach. We rule out the CP-conserving case, Apipi=Spipi=0, at the 99.93% confidence level. We discuss how these results constrain the value of the CKM angle phi2.Comment: 26 pages, 13 figures, submitted to Phys. Rev.

    Probing exotic phenomena at the interface of nuclear and particle physics with the electric dipole moments of diamagnetic atoms: A unique window to hadronic and semi-leptonic CP violation

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    The current status of electric dipole moments of diamagnetic atoms which involves the synergy between atomic experiments and three different theoretical areas -- particle, nuclear and atomic is reviewed. Various models of particle physics that predict CP violation, which is necessary for the existence of such electric dipole moments, are presented. These include the standard model of particle physics and various extensions of it. Effective hadron level combined charge conjugation (C) and parity (P) symmetry violating interactions are derived taking into consideration different ways in which a nucleon interacts with other nucleons as well as with electrons. Nuclear structure calculations of the CP-odd nuclear Schiff moment are discussed using the shell model and other theoretical approaches. Results of the calculations of atomic electric dipole moments due to the interaction of the nuclear Schiff moment with the electrons and the P and time-reversal (T) symmetry violating tensor-pseudotensor electron-nucleus are elucidated using different relativistic many-body theories. The principles of the measurement of the electric dipole moments of diamagnetic atoms are outlined. Upper limits for the nuclear Schiff moment and tensor-pseudotensor coupling constant are obtained combining the results of atomic experiments and relativistic many-body theories. The coefficients for the different sources of CP violation have been estimated at the elementary particle level for all the diamagnetic atoms of current experimental interest and their implications for physics beyond the standard model is discussed. Possible improvements of the current results of the measurements as well as quantum chromodynamics, nuclear and atomic calculations are suggested.Comment: 46 pages, 19 tables and 16 figures. A review article accepted for EPJ

    Development of Motorized Slewing Mirror Stage for the UFFO Project

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    The Ultra-Fast Flash Observatory (UFFO) is a space observatory for optical follow-ups of gamma ray bursts (GRBs), aiming to explore the first 60 seconds of GRBs optical emission. UFFO is utilized to catch early optical emissions from GRBs within few sec after trigger using a Gimbal mirror which redirects the optical path rather than slewing entire spacecraft. We have developed a 15 cm two-axis Gimbal mirror stage for the UFFO-Pathfinder which is going to be on board the Lomonosov satellite which is to be launched in 2013. The stage is designed for fast and accurate motion with given budgets of 3 kg of mass and 3 Watt of power. By employing stepping motors, the slewing mirror can rotate faster than 15 deg/sec so that objects in the UFFO coverage (60 deg × 60 deg) can be targeted in ~1 sec. The obtained targeting resolution is better 2 arcmin using a close-loop control with high precision rotary encoder. In this presentation, we will discuss details of design, manufacturing, space qualification tests, as well as performance tests
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