14 research outputs found

    Mathematical Educational Games : Perceptions of Special Education Teachers

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    Children lose 99 times out of hundred in almost every commercial game they play yet they do not stop playing games after such failures (McGonigal 2011). In fact, the more they fail the more they want to play games. The case is different when it comes to computer educational games. Children do not play them as often as these games are meant to be played. Therefore, the perceptions of the teachers who teach through such games are the focus of this study

    Group dynamics in flipped learning situations in higher education

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    Higher education has always been a firm supporter of traditional teacher oriented pedagogical approaches. However, reform of the pedagogical approaches is necessary in order to promote learning outcomes. In this research, the possibility of enhancing learning experiences and atmosphere among students and between students and tutor by group dynamic methods in flipped learning situations was investigated. Reflection is a key component in learning and group dynamics. Thence, reflection鈥檚 essentiality with group dynamics in flipped learning is explained. Furthermore, to support the above argument, meaningful learning theory is discussed. To undertake this research, mixed methods were used to analyse data retrieved with a questionnaire, reflections and observations, giving a diverse and comprehensive view of the subject. Data was collected from Lapland University students during flipped learning course in which group dynamics exercises had been integrated. Two core changes are proposed; using facilitation methodologies (group dynamics) to make a new pedagogical framework to reform teaching in higher education, and introducing group dynamics to educators and students using flipped learning in order to improve learning outcomes and promote meaningful learning

    Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

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    Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14路2 per cent (646 of 4544) and the 30-day mortality rate was 1路8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7路61, 95 per cent c.i. 4路49 to 12路90; P < 0路001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0路65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

    Identity, hyperreality and Science fiction : Matrix and Neuromancer

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    My Bachelor鈥檚 thesis is a comparative analysis between humans and machines in a science fiction novel (Neuromancer) and a movie (Matrix). I explored in these works how the machines used technologies to influence on the humans. I used examples of characters from the text and movie along with the references of other writers writing on the same topic to help convey my message. I explored mainly the identity and reality issues among characters. William Gibson in Neuromancer portrays that technology has become a part of human body. While in the Matrix we see how machines are taking control on humans. In my thesis I started with Neuromancer and write about identity and reality issues of characters and artificial intelligences. In the second part of the thesis I write the same with the characters of the movie Matrix but also I compared these characters with characters of Neuromancer. Some other discussions in my thesis are about hyperreality, simulation, simulacra with reference to mostly Baudrillard. Overall this thesis explores the issues of identity and reality to the characters in the works and also to the readers as well. Key Terms: Identity, Reality, Hyperreality, Simulation, Simulacra

    Identity, hyperreality and Science fiction : Matrix and Neuromancer

    No full text
    My Bachelor鈥檚 thesis is a comparative analysis between humans and machines in a science fiction novel (Neuromancer) and a movie (Matrix). I explored in these works how the machines used technologies to influence on the humans. I used examples of characters from the text and movie along with the references of other writers writing on the same topic to help convey my message. I explored mainly the identity and reality issues among characters. William Gibson in Neuromancer portrays that technology has become a part of human body. While in the Matrix we see how machines are taking control on humans. In my thesis I started with Neuromancer and write about identity and reality issues of characters and artificial intelligences. In the second part of the thesis I write the same with the characters of the movie Matrix but also I compared these characters with characters of Neuromancer. Some other discussions in my thesis are about hyperreality, simulation, simulacra with reference to mostly Baudrillard. Overall this thesis explores the issues of identity and reality to the characters in the works and also to the readers as well. Key Terms: Identity, Reality, Hyperreality, Simulation, Simulacra

    A review on life cycle assessment of different pipeline materials

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    Environmentally sustainable development needs techniques and tools to quantify and compare human activities environmental impacts for numerous products and services. However, providing products and services to society contributes to a variety of environmental consequences commonly known as environmental impacts. The environmental impact involves the consumption of resources, emissions into the environment, and other interventions like land use, ecotoxicity, etc. To develop environmentally conscious pipeline projects or infrastructure, the environmental impacts of its entire service life must be known. Besides, the life cycle assessment (LCA) is the most advanced tool for assessing the environmental impacts of the entire life of any product or service. The aim of this study is to review the environmental impact of different pipeline networks with different materials on which LCA has been performed. In order to see which phases of the life cycle of pipeline networks and which pipeline materials have higher energy consumption and have major environmental impacts. It has been noticed that the use/operational phase contributes the most to global warming potential (GWP) and has the greatest amount of energy consumption, which is concerning and cannot be overlooked. Now there is a need for some alternative approaches to pipeline networks for a sustainable future

    Molecular modeling of pyrrolo-pyrimidine based analogs as potential FGFR1 inhibitors: a scientific approach for therapeutic drugs

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    Fibroblast growth factor receptors 1 (FGFR1) is an emerging target for the development of anticancer drugs. Uncontrolled expression of FGFR1 is strongly associated with a number of different types of cancers. Apart from a few FGFR inhibitors, the FGFR family members have not been thoroughly studied to produce clinically effective anticancer drugs. The application of proper computational techniques may aid in understanding the mechanism of protein鈥搇igand complex formation, which may provide a better notion for developing potent FGFR1 inhibitors. In this study, a variety of computational techniques, including 3D-QSAR, flexible docking and MD simulation followed by MMGB/PBSA, H-bonds and distance analysis, have been performed to systematically explore the binding mechanism of pyrrolo-pyrimidine derivatives against FGFR1. The 3D-QSAR model was generated to deduce the structural determinants of FGFR1 inhibition. The high q2 and r2 values for the CoMFA and CoMSIA models indicated that the created 3D-QSAR models could reliably predict the bioactivities of FGFR1 inhibitors. The computed binding free energies (MMGB/PBSA) for the selected compounds were consistent with the ranking of their experimental binding affinities against FGFR1. Furthermore, per-residue energy decomposition analysis revealed that the residues Lys514 in catalytic region, Asn568, Glu571 in solvent accessible portion and Asp641 in DFG motif exhibited a strong tendency to mediate ligand鈥損rotein interactions through the hydrogen bonding and Van Der Waals interactions. These findings may benefit researchers in gaining better knowledge of FGFR1 inhibition and may serve as a guideline for the development of novel and highly effective FGFR1 inhibitors. Communicated by Ramaswamy H. Sarma</p

    Synergistic effect of recycling waste coconut shell ash, metakaolin, and calcined clay as supplementary cementitious material on hardened properties and embodied carbon of high strength concrete

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    Researchers are investigating eco-friendly binders like coconut shell ash (CSA), metakaolin (MK), and calcined clay (CC) as supplementary cementitious materials (SCM) in high-strength concrete (HSC). Abundantly available as industrial or agricultural waste, these materials, when combined with Portland cement (PC), offer synergistic benefits. This not only improves concrete performance but also addresses waste disposal issues, presenting a sustainable and environmentally friendly solution for long-term use in HSC production. However, this study performed on fresh and mechanical characteristics of HSC blended with CSA, MK, and CCA alone and together as SCM after 28 days of curing. A total of 504 samples of standard concrete were cast and the cubical samples were tested to achieve the targeted compressive strength about 80鈥疢Pa after 28 days. The experimental results indicated that the rise in tensile, flexural and compressive strengths of 9.62%, 8.27%, and 10.71% at 9% of CSA, MK, and CC as SCM after 28 days of curing. As SCM content increases, the density, porosity and water absorption of concrete decrease. Moreover, the workability of fresh concrete is getting reduced when the concentration of SCMs increases in HSC. In addition, the concrete's sustainability assessment revealed that employing 18% MK, CC, and CSA as SCM reduced carbon emissions by approximately 11.78%. It is suggested that using 9% CC, MK and CSA together in HSC yields the best results for practical applications in civil engineering
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