CARBON CAPTURE AND STORAGE(CCS) RESEARCH COLLABORATION TRENDS USING NETWORK ANALYSIS OF SCI PAPERS

Climate change has become one of the most important global agenda, and nations worldwide are taking actions to resolve the issue and contribute to the new climate change regime. In the case of South Korea, the new goal of reducing greenhouse gas emission to 37% below BAU(Business-As- Usual) was set. As a means to achieve this goal, the Korean government is actively investing in highly effective greenhouse reduction technologies such as solar cell, fuel cell, bioenergy, secondary battery, power IT, and CCS(Carbon Capture and Storage). This paper investigates the overall trend of CCS research by examining international CCS research collaboration characteristics through network analysis of SCI papers; collaboration network of Korea is analyzed in further detail. Such analysis helps understand the status of international research in the field of CCS, especially that of Korea

Plant Location Selection for Food Production by Considering the Regional and Seasonal Supply Vulnerability of Raw Materials

A production capacity analysis considering market demand and raw materials is very important to design a new plant. However, in the food processing industry, the supply uncertainty of raw materials is very high, depending on the production site and the harvest season, and further, it is not straightforward to analyze too complex food production systems by using an analytical optimization model. For these reasons, this study presents a simulation-based decision support model to select the right location for a new food processing plant. We first define three supply vulnerability factors from the standpoint of regional as well as seasonal instability and present an assessment method for supply vulnerability based on fuzzy quantification. The evaluated vulnerability scores are then converted into raw material supply variations for food production simulation to predict the quarterly production volume of a new food processing plant. The proposed selection procedure is illustrated using a case study of semiprocessed kimchi production. The best plant location is proposed where we can reduce and mitigate risks when supplying raw material, thereby producing a target production volume steadily

Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells

Exposure to particulate matter (PM) in ambient air is known to increase the risk of cardiovascular disorders and mortality. The cytotoxicity of PM is mainly due to the abnormal increase of reactive oxygen species (ROS), which damage cellular components such as DNA, RNA, and proteins. The correlation between PM exposure and human disorders, including mortality, is based on long-term exposure. In this study we have investigated acute responses of mucus-secreting goblet cells upon exposure to PM derived from a heavy diesel engine. To this end, we employed the mucociliary epithelium of amphibian embryos and human Calu-3 cells to examine PM mucotoxicity. Our data suggest that acute exposure to PM significantly impairs mucus secretion and results in the accumulation of mucus vesicles in the cytoplasm of goblet cells. RNA-seq analysis revealed that acute responses to PM exposure significantly altered gene expression patterns; however, known regulators of mucus production and the secretory pathway were not significantly altered. Interestingly, pretreatment with alpha-tocopherol nearly recovered the hyposecretion of mucus from both amphibian and human goblet cells. We believe this study demonstrates the mucotoxicity of PM and the protective function of alpha-tocopherol on mucotoxicity caused by acute PM exposure from heavy diesel engines

Permanent Hydrophilic Surface Formation by Ion Assisted Reaction

Since totally wettable hydrophilic polymer surfaces from hydrophobic polymers (PMMA, PTFE, PET and PC) have been demonstrated for the first time at Materials Research Society meeting, 1995 Fall meeting, Boston, the application of ion assisted reaction (IAR), in which energetic ions (0.5~1.5 keV) are irradiated on materials with blowing reactive gases near the irradiating surfaces, has been extended to various polymer, ceramic and metal for creating permanent hydrophilic surfaces. The surface energy was measured by Youngs equation and the highest energy, Es, of 60~70 mN/m, which is similar to surface energy of water (Es of H2O : 72 mN/m) is obtained by controlling ion dose, energy, and amount of blown gas. The higher surface energy of materials possesses the more wettable surface, and relation between wettability and adhesion has been discussed. The remarkable result is the strong adhesion of inert nonattachable material such as Pt on the modified surface. The improvements of adhesions, wettability and surface energy are mainly due to polar force and hydrophilic functional groups such as C=O, (C=O)-O, C-O, etc. on the modified surface without surface damage by surface analyses. Advantages of the method are (1) high reproducibility, (2) simplicity, (3) changing ability of wettability degree, and (4) easy connection to conventional semiconductor process line. Improvements of efficiencies by changing heat transfer coefficients have been presented for the compact heat exchanger system

Human microglial cells synthesize albumin in brain

Albumin has been implicated in Alzheimer's disease since it can bind to and transport amyloid beta, the causative agent; albumin is also a potent inhibitor of amyloid beta polymerization. In a pilot phase study of Human Brain Proteome Project, we found evidence that albumin may be synthesized in immortalized human microglial cells, human primary microglial cells, and human fetal and adult brain tissues. We also found the synthesis and secretion is enhanced upon microglial activation by Amyloid [beta]~1-42~, lipopolysaccharide treatment or human Alzheimer's brain

THERMAL HYDRAULIC ISSUES OF CONTAINMENT FILTERED VENTING SYSTEM FOR A LONG OPERATING TIME

This study investigated the thermal hydraulic issues in the Containment Filtered Venting System (CFVS) for a long operating time using the MELCOR computer code. The modeling of the CFVS, including the models for pool scrubbing and the filter, was added to the input file for the OPR-1000, and a Station Blackout (SBO) was chosen as an accident scenario. Although depressurization in the containment building as a primary objective of the CFVS was successful, the decontamination feature by scrubbing and filtering in the CFVS for a long operating time could fail by the continuous evaporation of the scrubbing solution. After the operation of the CFVS, the atmosphere temperature in the CFVS became slightly above the water saturation temperature owing to the release of an amount of steam with high temperature from the containment building to the scrubbing solution. Reduced pipe diameters at the inlet and outlet of the CFVS vessel mitigated the evaporation of scrubbing water by controlling the amount of high-temperature steam and the water saturation temperature

mtDNAmanager: a Web-based tool for the management and quality analysis of mitochondrial DNA control-region sequences

BACKGROUND: For the past few years, scientific controversy has surrounded the large number of errors in forensic and literature mitochondrial DNA (mtDNA) data. However, recent research has shown that using mtDNA phylogeny and referring to known mtDNA haplotypes can be useful for checking the quality of sequence data. RESULTS: We developed a Web-based bioinformatics resource "mtDNAmanager" that offers a convenient interface supporting the management and quality analysis of mtDNA sequence data. The mtDNAmanager performs computations on mtDNA control-region sequences to estimate the most-probable mtDNA haplogroups and retrieves similar sequences from a selected database. By the phased designation of the most-probable haplogroups (both expected and estimated haplogroups), mtDNAmanager enables users to systematically detect errors whilst allowing for confirmation of the presence of clear key diagnostic mutations and accompanying mutations. The query tools of mtDNAmanager also facilitate database screening with two options of "match" and "include the queried nucleotide polymorphism". In addition, mtDNAmanager provides Web interfaces for users to manage and analyse their own data in batch mode. CONCLUSION: The mtDNAmanager will provide systematic routines for mtDNA sequence data management and analysis via easily accessible Web interfaces, and thus should be very useful for population, medical and forensic studies that employ mtDNA analysis. mtDNAmanager can be accessed at http://mtmanager.yonsei.ac.krope

Papez Circuit Observed by in vivo Human Brain With 7.0T MRI Super-Resolution Track Density Imaging and Track Tracing

The Papez circuit has been considered as an important anatomical substrate involved in emotional experience. However, the circuit remains difficult to elucidate in the human brain due to the resolution limit of current neuroimaging modalities. In this article, for the first time, we report the direct visualization of the Papez circuit with 7-Tesla super-resolution magnetic resonance tractography. Two healthy, young male subjects (aged 30 and 35 years) were recruited as volunteers following the guidelines of the institutional review board (IRB). Track density imaging (TDI) generation with track tracing was performed using MRtrix software package. With these tools, we were able to visualize the entire Papez circuit. We believe this is the first study to visualize the complete loop of the Papez circuit, including the perforant path (PP), thalamocortical fibers of the anterior nucleus (AN), and mammillothalamic tract (MTT), which were hitherto difficult to visualize by conventional imaging techniques