743 research outputs found

    Emotional agents at the square lattice

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    We introduce and investigate by numerical simulations a number of models of emotional agents at the square lattice. Our models describe the most general features of emotions such as the spontaneous emotional arousal, emotional relaxation, and transfers of emotions between different agents. Group emotions in the considered models are periodically fluctuating between two opposite valency levels and as result the mean value of such group emotions is zero. The oscillations amplitude depends strongly on probability ps of the individual spontaneous arousal. For small values of relaxation times tau we observed a stochastic resonance, i.e. the signal to noise ratio SNR is maximal for a non-zero ps parameter. The amplitude increases with the probability p of local affective interactions while the mean oscillations period increases with the relaxation time tau and is only weakly dependent on other system parameters. Presence of emotional antenna can enhance positive or negative emotions and for the optimal transition probability the antenna can change agents emotions at longer distances. The stochastic resonance was also observed for the influence of emotions on task execution efficiency.Comment: 28 pages, 19 figures, 3 table

    Uncovering supplementary information from questionnaire inquiry on physical ability with the aim to develop psycho-educational intervention : an example of a study using the SF-36 questionnaire among convalescents after acute pancreatitis

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    The aim of this paper was to complete a series of our own reports on health-related outcomes of rehabilitation following successful clinical therapy in Poland, based on data from a questionnaire survey using the SF-36 questionnaire, on a group of N = 142 participants hospitalized for acute pancreatitis at General Surgery in the Jagiellonian University of Krakow from 2000 to 2006. The data from the questionnaire survey were used to estimate two auxiliary individual attributes of the survey participants: the predictable ability to accept (PAA) any fixed ordering of scale items; and the inclination to avoid extreme scores (AES). The participants of the study differed significantly with respect to their individual PF AES, and PAA scores, N=48 persons didn't agree with the standard ordering of PF items of SF-36, N=30 persons agreed with any possible ordering. The findings of this study have some practical worth: first, in case of a need to reveal the patient's true ordering of the questionnaire items, it can be concluded that the persons with a great predictable ability to accept any ordering should be examined once more with some special technique. It seems to be sensible that patients with a quite different inclination to avoid extreme scores need a somewhat distinct style of motivation for healthy behavior

    PCN17 SYSTEMATIC REVIEW OF THE EFFICACY AND SAFETY OF IMIQUIMOD 5% CREAM FOR THE TREATMENT OF SUPERFICIAL BASAL CELL CARCINOMA

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    Quantifying layer similarity in multiplex networks: A systematic study

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    © 2018 The Authors. Computing layer similarities is an important way of characterizing multiplex networks because various static properties and dynamic processes depend on the relationships between layers. We provide a taxonomy and experimental evaluation of approaches to compare layers in multiplex networks. Our taxonomy includes, systematizes and extends existing approaches, and is complemented by a set of practical guidelines on how to apply them

    Networks of companies and branches in Poland

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    In this study we consider relations between companies in Poland taking into account common branches they belong to. It is clear that companies belonging to the same branch compete for similar customers, so the market induces correlations between them. On the other hand two branches can be related by companies acting in both of them. To remove weak, accidental links we shall use a concept of threshold filtering for weighted networks where a link weight corresponds to a number of existing connections (common companies or branches) between a pair of nodes.Comment: 13 pages, 10 figures and 4 table

    Scaling of human behavior during portal browsing

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    We investigate transitions of portals users between different subpages. A weighted network of portals subpages is reconstructed where edge weights are numbers of corresponding transitions. Distributions of link weights and node strengths follow power laws over several decades. Node strength increases faster than linearly with node degree. The distribution of time spent by the user at one subpage decays as power law with exponent around 1.3. Distribution of numbers P(z) of unique subpages during one visit is exponential. We find a square root dependence between the average z and the total number of transitions n during a single visit. Individual path of portal user resembles of self-attracting walk on the weighted network. Analytical model is developed to recover in part the collected data.Comment: 6 pages, 7 figure

    Acute febrile torticollis in youth: clinical investigation and current management Naouar Ouattassi

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    Acute febrile torticollis in children is a rare and a special clinical picture of variable causes. It may indicate an inflammatory or an infectious pathology affecting any of the anatomical structures of the neck. Treatment is quite clearly defined, and it may be a therapeutic emergency. It is a condition that all ENT specialists must be familiar with since they are most likely to be the first physician to whom such a child is brough

    A homology model of restriction endonuclease SfiI in complex with DNA

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    BACKGROUND: Restriction enzymes (REases) are commercial reagents commonly used in recombinant DNA technologies. They are attractive models for studying protein-DNA interactions and valuable targets for protein engineering. They are, however, extremely divergent: the amino acid sequence of a typical REase usually shows no detectable similarities to any other proteins, with rare exceptions of other REases that recognize identical or very similar sequences. From structural analyses and bioinformatics studies it has been learned that some REases belong to at least four unrelated and structurally distinct superfamilies of nucleases, PD-DxK, PLD, HNH, and GIY-YIG. Hence, they are extremely hard targets for structure prediction and homology-based inference of sequence-function relationships and the great majority of REases remain structurally and evolutionarily unclassified. RESULTS: SfiI is a REase which recognizes the interrupted palindromic sequence 5'GGCCNNNN^NGGCC3' and generates 3 nt long 3' overhangs upon cleavage. SfiI is an archetypal Type IIF enzyme, which functions as a tetramer and cleaves two copies of the recognition site in a concerted manner. Its sequence shows no similarity to other proteins and nothing is known about the localization of its active site or residues important for oligomerization. Using the threading approach for protein fold-recognition, we identified a remote relationship between SfiI and BglI, a dimeric Type IIP restriction enzyme from the PD-DxK superfamily of nucleases, which recognizes the 5'GCCNNNN^NGGC3' sequence and whose structure in complex with the substrate DNA is available. We constructed a homology model of SfiI in complex with its target sequence and used it to predict residues important for dimerization, tetramerization, DNA binding and catalysis. CONCLUSIONS: The bioinformatics analysis suggest that SfiI, a Type IIF enzyme, is more closely related to BglI, an "orthodox" Type IIP restriction enzyme, than to any other REase, including other Type IIF REases with known structures, such as NgoMIV. NgoMIV and BglI belong to two different, very remotely related branches of the PD-DxK superfamily: the α-class (EcoRI-like), and the β-class (EcoRV-like), respectively. Thus, our analysis provides evidence that the ability to tetramerize and cut the two DNA sequences in a concerted manner was developed independently at least two times in the evolution of the PD-DxK superfamily of REases. The model of SfiI will also serve as a convenient platform for further experimental analyses
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