Factories without Smoke

They are China’s most precious economic asset: migrant workers. Each year, millions upon millions untie themselves from the rhythms of rural life to chase down a future in the prestige cities and sudden boomtowns of the eastern and southern coasts. In doing so, they begin a dramatic journey from farmer to worker; one marked by a profound shift from cultivating land they own, to producing goods they don’t. But few will be allowed to transform completely. Oft belittled for their unsophisticated ways, to urbanites they are forever “waidiren” — outside people. Most will be marked by their speech the moment they open their mouths

Factories without Smoke: Wang Jia Yi and Gao Tian Ci

Wang Jia Yi and Gao Tian Ci, Dalian to San Li Village, Anhui Provinc

The Coastie Initiative

Coastline change is an ever-increasing area of interest with a multitude of research opportunities. The Coastie Initiative was developed with Parks Canada to crowdsource the collection of regular imagery of coastal morphology, building a large dataset for tracking shoreline change. Citizens can partake in this growing program by submitting a ‘Coastie’ through the web-based platform. At every site, a phone cradle, designed to standardize images, is accompanied by an informational panel and a QR code. Visitors can use the QR code to quickly access the submission wizard. After submission, the image is saved and awaits classification by researchers. The intended development of the project includes an achievement system to promote user retention, an automated classification system to eliminate manual labelling, and an ocean literacy stream as an effort to educate and inform the public. The initiative was launched during the fall of 2021 with 5 locations. The Coastie program is a collaboration that has developed from the global CoastSnap Community Beach Monitoring movement that began in Australia in 2017. Using the early prototype dataset, coastal change can be quantified from repeat geo-rectified images. These capture deposition/erosion of the beach and dune topography in response to ambient environmental conditions or higher energy storm events. This dataset will serve as a baseline to monitor how coastal systems respond to climate change, including sea level rise, change in storm activity, and reduction in sea ice coverage. The Coastie Initiative allows citizen scientists to influence coastline exploration participating alongside motivated researchers

Beyond just species: is Africa the most taxonomically diverse bird continent?

We analysed avian diversity in 8 similar-sized regions of Africa, and in an additional 16 regions spread across the world; half of these 24 regions were tropical and the other half were temperate. For each region, counts of species, genus, family and order were recorded rather than only a species count. We assert that this approach gives more accurate insights into diversity patterns, as we show that in relatively species-rich parts of the world species are on average taxonomically more similar to each other than in species-poor areas. Northwestern South America is the world's most species-rich region for birds, but we show that sub-Saharan Africa has greater diversity at higher taxonomic levels and is thus arguably the richest corner of the world for birds: the Mozambique–Zimbabwe region displays the highest diversity at the order level (with 30 orders), with all other sub-Saharan regions having between 27 and 29 orders each. Northern India is also extremely diverse (surprisingly so for a marginally temperate region) at all taxonomic levels below that of order. We hope that our study might generate further analyses of avian diversity beyond the species level

Compassion satisfaction and fatigue: An investigation into levels being reported by radiotherapy students

Introduction: Studies have investigated the prevalence of compassion satisfaction and compassion fatigue in various healthcare professions. However, the majority of evidence is linked to the nursing profession and little is known about paramedical professions such as radiography and even less is known about its prevalence in students. The purpose of this study was to describe the levels of compassion satisfaction and compassion fatigue in the student population and how they varied in time. Methods: Students undertaking radiotherapy training at the researcher’s host sites were surveyed using the Professional Quality of Life questionnaire at the end of each final clinical bock in each year of their training. Results & Conclusion: During the three years of training compassion satisfaction falls and burnout increases in the student population, although the change is not significant. Secondary traumatic stress increases significantly during the 3 years of training, F=5.725, p=0.005. Considerable variation also exists in the three scores dependent on the student’s clinical training site. Relationships are also observed between some personality traits, particularly conscientiousness and neuroticism and compassion scores

Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components

Biochemical circuits made of rationally designed DNA molecules are proofs of concept for embedding control within complex molecular environments. They hold promise for transforming the current technologies in chemistry, biology, medicine and material science by introducing programmable and responsive behaviour to diverse molecular systems. As the transformative power of a technology depends on its accessibility, two main challenges are an automated design process and simple experimental procedures. Here we demonstrate the use of circuit design software, combined with the use of unpurified strands and simplified experimental procedures, for creating a complex DNA strand displacement circuit that consists of 78 distinct species. We develop a systematic procedure for overcoming the challenges involved in using unpurified DNA strands. We also develop a model that takes synthesis errors into consideration and semi-quantitatively reproduces the experimental data. Our methods now enable even novice researchers to successfully design and construct complex DNA strand displacement circuits

Genetic parameters of sole lesion recovery in Holstein cows

Sole hemorrhage and sole ulcers, referred to as sole lesions, are important causes of lameness in dairy cattle. The objective of this study was to estimate the genetic parameters of a novel trait reflecting how well cows recovered from sole lesions and the genetic correlation of this trait with overall susceptibility to sole lesions. A cohort of Holstein dairy cows was prospectively enrolled on 4 farms and assessed at 4 timepoints: before calving, immediately after calving, in early lactation, and in late lactation. At each timepoint, sole lesions were recorded at the claw level by veterinary surgeons and used to define 2 binary traits: (1) susceptibility to sole lesions-whether animals were affected with sole lesions at least once during the study or were unaffected at every assessment, and (2) sole lesion recovery-whether sole lesions healed between early and late lactation. Animals were genotyped and pedigree details extracted from the national database. Analyses were conducted with BLUPF90 software in a single-step framework; genetic parameters were estimated from animal threshold models using Gibbs sampling. The genetic correlation between both traits was approximated as the correlation between genomic estimated breeding values, adjusting for their reliabilities. A total of 2,025 animals were used to estimate the genetic parameters of sole lesion susceptibility; 44% of animals recorded a sole lesion at least once during the study period. The heritability of sole lesion susceptibility, on the liability scale, was 0.25 (95% highest density interval = 0.16-0.34). A total of 498 animals were used to estimate the genetic parameters of sole lesion recovery; 71% of animals had recovered between the early and late lactation assessments. The heritability of sole lesion recovery, on the liability scale, was 0.27 (95% highest density interval = 0.02-0.52). The approximate genetic correlation between each trait was -0.11 (95% confidence interval = -0.20 to -0.02). Our results indicate that recovery from sole lesions is heritable. If this finding is corroborated in further studies, it may be possible to use selective breeding to reduce the frequency of chronically lame cows. As sole lesion recovery appears to be weakly genetically related to sole lesion susceptibility, successful genetic improvement of sole lesion recovery would benefit from selection on this trait directly.</p

Inhibitory activity of extracts of Hebridean brown seaweeds on lipase activity

The effect of three Hebridean brown seaweeds on lipase activity was assessed using a turbidimetric lipase activity assay and an in vitro simulation of the upper digestive tract. The preparations of Ascophyllum nodosum, Fucus vesiculosus, and Pelvetia canaliculata were tested; whole seaweed homogenate, sodium carbonate extract, and ethanol extracts (pellet and supernatant were tested separately). All extracts showed significant inhibition of lipase, suggesting multiple bioactive agents, potentially including alginates, fucoidans, and polyphenols. Whole homogenate extract of F. vesiculosus was the most potent inhibitor of Lipase (IC50 = 0.119 mg mL-1), followed by ethanol supernatant (IC50 = 0.159 mg mL-1) while ethanol pellet and sodium carbonate extract showed relatively weaker inhibition (IC50 = 0.360 mg mL-1 and IC50 = 0.969 mg mL-1 respectively). For A. nodosum and P. canaliculata, strongest inhibition occurred with ethanol pellet (IC50 = 0.238 and 0.228 mg mL−1, respectively). These inhibitory effects were validated in a model gut system. The data presented herein suggests the use of seaweed as a potential weight management tool is deserving of further investigation

Spectral simplicity and asymptotic separation of variables

We describe a method for comparing the real analytic eigenbranches of two families of quadratic forms that degenerate as t tends to zero. One of the families is assumed to be amenable to `separation of variables' and the other one not. With certain additional assumptions, we show that if the families are asymptotic at first order as t tends to 0, then the generic spectral simplicity of the separable family implies that the eigenbranches of the second family are also generically one-dimensional. As an application, we prove that for the generic triangle (simplex) in Euclidean space (constant curvature space form) each eigenspace of the Laplacian is one-dimensional. We also show that for all but countably many t, the geodesic triangle in the hyperbolic plane with interior angles 0, t, and t, has simple spectrum.Comment: 53 pages, 2 figure