Tri-axial Octupole Deformations and Shell Structure

Manifestations of pronounced shell effects are discovered when adding nonaxial octupole deformations to a harmonic oscillator model. The degeneracies of the quantum spectra are in a good agreement with the corresponding main periodic orbits and winding number ratios which are found by classical analysis.Comment: 10 pages, Latex, 4 postscript figures, to appear in JETP Letter

Parametrization of the octupole degrees of freedom

A simple parametrization for the octupole collective variables is proposed and the symmetries of the wave functions are discussed in terms of the solutions corresponding to the vibrational limit. [PACS: 21.60Ev, 21.60.Fw, 21.10.Re]Comment: 14 page

Intrinsic vs. laboratory frame description of the deformed nucleus 48Cr

The collective yrast band of the nucleus $^{48}$Cr is studied using the spherical shell model and the HFB method. Both approaches produce basically the same axially symmetric intrinsic state up to the - accurately reproduced - observed backbending. Agreement between both calculations extends to most observables. The only significant discrepancy comes from the static moments of inertia and can be attributed to the need of a more refined treatment of pairing correlations in the HFB calculation.Comment: 4 pages, RevTeX 3.0 using psfig, 6 Postscript figures included using uufile

Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity

Observational epidemiological studies indicate that endometriosis and migraine co-occur within individuals more than expected by chance. However, the aetiology and biological mechanisms underlying their comorbidity remain unknown. Here we examined the relationship between endometriosis and migraine using genome-wide association study (GWAS) data. Single nucleotide polymorphism (SNP) effect concordance analysis found a significant concordance of SNP risk effects across endometriosis and migraine GWAS. Linkage disequilibrium score regression analysis found a positive and highly significant genetic correlation (rG = 0.38, P = 2.30 × 10−25) between endometriosis and migraine. A meta-analysis of endometriosis and migraine GWAS data did not reveal novel genome-wide significant SNPs, and Mendelian randomisation analysis found no evidence for a causal relationship between the two traits. However, gene-based analyses identified two novel loci for migraine. Also, we found significant enrichment of genes nominally associated (Pgene 0.05) with both traits (Pbinomial-test = 9.83 × 10−6). Combining gene-based p-values across endometriosis and migraine, three genes, two (TRIM32 and SLC35G6) of which are at novel loci, were genome-wide significant. Genes having Pgene 0.1 for both endometriosis and migraine (Pbinomial-test = 1.85 ×10−°3) were significantly enriched for biological pathways, including interleukin-1 receptor binding, focal adhesion-PI3K-Akt-mTOR-signaling, MAPK and TNF-α signalling. Our findings further confirm the comorbidity of endometriosis and migraine and indicate a non-causal relationship between the two traits, with shared genetically-controlled biological mechanisms underlying the co-occurrence of the two disorders

Intruder bands and configuration mixing in the lead isotopes

A three-configuration mixing calculation is performed in the context of the interacting boson model with the aim to describe recently observed collective bands built on low-lying $0^+$ states in neutron-deficient lead isotopes. The configurations that are included correspond to the regular, spherical states as well as two-particle two-hole and four-particle four-hole excitations across the Z=82 shell gap.Comment: 20 pages, 4 figures, accepted by PRC, reference added for section 1 in this revised versio

A side-by-side comparison of Daya Bay antineutrino detectors

The Daya Bay Reactor Neutrino Experiment is designed to determine precisely the neutrino mixing angle $\theta_{13}$ with a sensitivity better than 0.01 in the parameter sin$^22\theta_{13}$ at the 90% confidence level. To achieve this goal, the collaboration will build eight functionally identical antineutrino detectors. The first two detectors have been constructed, installed and commissioned in Experimental Hall 1, with steady data-taking beginning September 23, 2011. A comparison of the data collected over the subsequent three months indicates that the detectors are functionally identical, and that detector-related systematic uncertainties exceed requirements.Comment: 24 pages, 36 figure