Elaboration d’une stratégie marketing afin d’augmenter l’attractivité touristique de Vercorin

L’objectif principal de ce travail est d’apporter des solutions et d’émettre des recommandations aux acteurs touristiques de Vercorin dans le but d’augmenter l’attractivité touristique de la destination

Switchable Adhesion of Soft Composites Induced by a Magnetic Field

Switchable adhesives have the potential to improve the manufacturing and recycling of parts and to enable new modes of motility for soft robots. Here, we demonstrate magnetically-switchable adhesion of a two-phase composite to non-magnetic objects. The composite's continuous phase is a silicone elastomer, and the dispersed phase is a magneto-rheological fluid. The composite is simple to prepare, and to mould to different shapes. When a magnetic field is applied, the magneto-rheological fluid develops a yield stress, which dramatically enhances the composite's adhesive properties. We demonstrate up to a nine-fold increase of the pull-off force of non-magnetic objects in the presence of a 250 mT field

Profession d'avocat et loi sur le marché intérieur

Les conditions d'agrément des avocats employés par des études multidisciplinaires d'avocats organisées sous la forme de société anonyme ne sont pas régies explicitement par le droit fédéral. Des pratiques cantonales divergentes se sont développées. Dans le canton de Zurich, cette forme de l'activité d'avocat a été admise à certaines conditions. Selon deux arrêts de la Cour de Justice de Genève rendus en octobre 2016, cette organisation n'est pas admissible. Une étude multidisciplinaire d'avocat dont le siège est à Zurich ne dispose au demeurant pas du droit de s'établir dans le canton de Genève en application de la loi fédérale sur le marché intérieur (« LMI »). La Cour de droit administratif et public du Tribunal cantonal du canton de Vaud a, quant à elle, a considéré, dans un arrêt de septembre 2016, la LMI inapplicable, mais a admis une étude multidisciplinaire d'avocats organisée sous la forme d'une société anonyme selon ses propres critères. Gardienne de l'application de la LMI, la Commission de la concurrence (« Comco ») a récemment annoncé, dans son rapport annuel 2016, avoir fait recours auprès du Tribunal fédéral contre les jugements de ces deux instances cantonales

Hierarchically Porous Iron Alloys with High Sintering Resistance During Cyclic Steam Oxidation and Hydrogen Reduction

Hydrogen release/storage materials for iron/air batteries are fabricated as Fe-16Mo and Fe-24Ni (at.%) lattices via 3D-extrusion printing of foamed inks containing oxide microparticles, followed by H2 reduction and sintering. A hierarchical open porosity is designed: (i) channels between walls created during printing, (ii) mesopores within walls, created during ink foaming, and (iii) micropores within ligaments between mesopores, created from partial sintering metal particles and gas escape during cycling. When subjected to H2/H2O redox cycling at 800 & DEG;C, the lattices of both compositions gradually undergo sintering. The Fe-16Mo lattice remains fully redox-active after 50 cycles unlike the Fe-24Ni lattice, which loses 90% of its redox capacity after 30 cycles. The increased lifetime of the Fe-16Mo lattice is attributed to the sintering inhibition of Mo, the formation of a mixture of oxide phases in the oxidized state, and the cyclic formation of submicron Fe2Mo by reduction of MoO2 and Fe2Mo3O8. The microstructure of the foamed walls is examined throughout cycling to track changes in morphology and composition. These are correlated to volume and porosity changes in the lattice. A comparison is made to previously-studied Fe-Mo and Fe-Ni freeze-cast lamellar foams, and variations in performance are discussed in the context of the different architectures.Fe-16Mo and Fe-24Ni lattices made by 3D-extrusion printing of foamed inks, for use in rechargeable metal/oxide batteries, are tested for their high-temperature resistance to degradation. The Fe-24Ni lattices lose capacity after 20 cycles, but the Fe-16Mo lattices maintain their capacity and reaction times for 50 cycles due to the hierarchical open porosity (channels, mesopores, micropores) designed into each lattice.imageISSN:1616-3028ISSN:1616-301

Safety of live vaccines on immunosuppressive or immunomodulatory therapy—a retrospective study in three Swiss Travel Clinics

Background Patients increasingly benefit from immunosuppressive/immunomodulatory medications for a range of conditions allowing them a lifestyle similar to healthy individuals, including travel. However, the administration of live vaccines to immunodeficient patients bears the risk of replication of the attenuated vaccine microorganism. Therefore, live vaccines are generally contraindicated on immunosuppression. Data on live vaccinations on immunosuppressive/immunomodulatory medication are scarce. We identified all travellers seeking pre-travel advice in three Swiss travel clinics with a live vaccine during immunosuppressive/immunomodulatory therapy to ascertain experienced side effects. A retrospective and multi-centre study design was chosen to increase the sample size. Methods This study was conducted in the travel clinics of the University of Zurich; the Swiss TPH, Basel; and Geneva University Hospitals. Travellers on immunosuppressive/immunomodulatory therapy who received live vaccines [yellow fever vaccination (YFV), measles/mumps/rubella (MMR), varicella and/ or oral typhoid vaccination (OTV)] between 2008 and 2015 were identified and interviewed. A total of 60 age- and sex-matched controls (matched to Basel/Zurich travel clinics travellers) were included. Results Overall, 197 patients were identified. And 116 patients (59%) and 60 controls were interviewed. YFV was administered 92 times, MMR 21 times, varicella 4 times and OTV 6 times to patients on immunosuppressive/immunomodulatory therapy. Most common medications were corticosteroids (n = 45), mesalazine (n = 28) and methotrexate (n = 19). Live vaccines were also administered on biological treatment, e.g. TNF-alpha inhibitors (n = 8). Systemic reactions were observed in 12.2% of the immunosuppressed vs 13.3% of controls; local reactions in 7.8% of the immunosuppressed vs 11.7% of controls. In controls, all reactions were mild/moderate. In the immunosuppressed, 2/21 severe reactions occurred: severe local pain on interferon-beta and severe muscle/joint pain on sulfasalazine. Conclusion Safety of live vaccines given to immunosuppressed patients cannot be concluded. However, it is re-assuring that in the examined patient groups no serious side effects or infections by the attenuated vaccine strain occurred

Switchable adhesion of soft composites induced by a magnetic field

Switchable adhesives have the potential to improve the manufacturing and recycling of parts, and to enable new modes of motility for soft robots. Here, we demonstrate magnetically-switchable adhesion of a two-phase composite to non-magnetic objects. The composite's continuous phase is a silicone elastomer, and the dispersed phase is a magneto-rheological fluid. The composite is simple to prepare, and to mold into different shapes. When a magnetic field is applied, the magneto-rheological fluid develops a yield stress, which dramatically enhances the composite's adhesive properties. We demonstrate up to a nine-fold increase of the pull-off force of non-magnetic objects in the presence of a 250 mT field.ISSN:1744-683XISSN:1744-684

Bioprospecting of a Metschnikowia pulcherrima indigenous strain for Chasselas winemaking in 2022 vintage

Interest in Metschnikowia (M.) pulcherrima is growing in the world of winemaking. M. pulcherrima is used both to protect musts from microbial spoilage and to modulate the aromatic profile of wines. Here, we describe the isolation, characterization, and use of an autochthonous strain of M. pulcherrima in the vinification of Chasselas musts from the 2022 vintage. M. pulcherrima was used in co-fermentation with Saccharomyces cerevisiae at both laboratory and experimental cellar scales. Our results showed that M. pulcherrima does not ferment sugars but has high metabolic activity, as detected by flow cytometry. Furthermore, sensory analysis showed that M. pulcherrima contributed slightly to the aromatic profile when compared to the control vinifications. The overall results suggest that our bioprospecting strategy can guide the selection of microorganisms that can be effectively used in the winemaking process