4,767 research outputs found

    Chapin M. Gerdine to Clint Chapin (1889 November 2)

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    Chapin writes to his cousin Clint about purchasing an oxidized handle walking stick and sending it to him in Mississippihttps://egrove.olemiss.edu/ciwar_corresp/1126/thumbnail.jp

    Chapin M. Gerdine to Emily McKinstry Chapin (1892 April 25)

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    Chapin explains that due to losses incurred by recent heavy flooding they are forced to ask Uncle Ed [E.E.C. Chapin, Roxana\u27s half-brother], to pay the interest on a loanhttps://egrove.olemiss.edu/ciwar_corresp/1134/thumbnail.jp

    Healthcare Price Transparency: Policy Approaches and Estimated Impacts on Spending

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    Healthcare price transparency discussions typically focus on increasing patients' access to information about their out-of-pocket costs, but that focus is too narrow and should include other audiences -- physicians, employers, health plans and policymakers -- each with distinct needs and uses for healthcare price information. Greater price transparency can reduce U.S. healthcare spending.For example, an estimated 100billioncouldbesavedoverthenext10yearsifthreeselectinterventionswereundertaken.However,mostoftheprojectedsavingscomefrommakingpriceinformationavailabletoemployersandphysicians,accordingtoananalysisbyresearchersattheformerCenterforStudyingHealthSystemChange(HSC).Basedonthecurrentavailabilityandmodestimpactofplan−basedtransparencytools,requiringallprivateplanstoprovidepersonalizedout−of−pocketpricedatatoenrolleeswouldreducetotalhealthspendingbyanestimated100 billion could be saved over the next 10 years if three select interventions were undertaken. However, most of the projected savings come from making price information available to employers and physicians, according to an analysis by researchers at the former Center for Studying Health System Change (HSC). Based on the current availability and modest impact of plan-based transparency tools, requiring all private plans to provide personalized out-of-pocket price data to enrollees would reduce total health spending by an estimated 18 billion over the next decade. While 18billionisasubstantialdollaramount,itislessthanatenthofapercentofthe18 billion is a substantial dollar amount, it is less than a tenth of a percent of the 40 trillionin total projected health spending over the same period. In contrast, using state all-payer claims databases to gather and report hospital-specific prices might reduce spending by an estimated $61 billion over 10 years.The effects of price transparency depend critically on the intended audience, the decision-making context and how prices are presented. And the impact of price transparency can be greatly amplified if target audiences are able and motivated to act on the information. Simply providing prices is insufficient to control spending without other shifts in healthcare financing, including changes in benefit design to make patients more sensitive to price differences among providers and alternative treatments. Other reforms that can amplify the impact of price transparency include shifting from fee-for-service payments that reward providers for volume to payment methods that put providers at risk for spending for episodes of care or defined patient populations. While price transparency alone seems unlikely to transform the healthcare system, it can play a needed role in enabling effective reforms in value-based benefit design and provider payment

    Postcard: W. E. Marcy\u27s Exhibit

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    This black and white photographic postcard features a variety of vegetables and grains affixed to a white board for display. A handwritten sign is at the top of the display. The display is propped up on two books that are placed on a chair. A wallpapered wall is in the back ground. There is handwriting on the back of the card.https://scholars.fhsu.edu/tj_postcards/1205/thumbnail.jp

    Mathematical modeling of the dynamic mechanical behavior of neighboring sarcomeres in actin stress fibers

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    pre-printActin stress fibers (SFs) in live cells consist of series of dynamic individual sarcomeric units. Within a group of consecutive SF sarcomeres, individual sarcomeres can spontaneously shorten or lengthen without changing the overall length of this group, but the underlying mechanism is unclear. We used a computational model to test our hypothesis that this dynamic behavior is inherent to the heterogeneous mechanical properties of the sarcomeres and the cytoplasmic viscosity. Each sarcomere was modeled as a discrete element consisting of an elastic spring, a viscous dashpot and an active contractile unit all connected in parallel, and experiences forces as a result of actin filament elastic stiffness, myosin II contractility, internal viscoelasticity, or cytoplasmic drag. When all four types of forces are considered, the simulated dynamic behavior closely resembles the experimental observations, which include a low-frequency fluctuation in individual sarcomere length and compensatory lengthening and shortening of adjacent sarcomeres. Our results suggest that heterogeneous stiffness and viscoelasticity of actin fibers, heterogeneous myosin II contractility, and the cytoplasmic drag are sufficient to cause spontaneous fluctuations in SF sarcomere length. Our results shed new light to the dynamic behavior of SF and help design experiments to further our understanding of SF dynamics

    High Angular Resolution Observations of Four Candidate BLAST High-Mass Starless Cores

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    We discuss high-angular resolution observations of ammonia toward four candidate high-mass starless cores (HMSCs). The cores were identified by the Balloon-borne Large Aperture Submillimeter Telescope (BLAST) during its 2005 survey of the Vulpecula region where 60 compact sources were detected simultaneously at 250, 350, and 500 micron. Four of these cores, with no IRAS-PSC or MSX counterparts, were observed with the NRAO Very Large Array (VLA) in the NH3(1,1) and (2,2) spectral lines. Our observations indicate that the four cores are cold (Tk <~ 14K) and show a filamentary and/or clumpy structure. They also show a significant velocity substructure within ~1km/s. The four BLAST cores appear to be colder and more quiescent than other previously observed HMSC candidates, suggesting an earlier stage of evolution.Comment: Submitted to the Astrophysical Journal on January 22, 2010. Accepted for publication on April 15, 2010. The paper has 21 pages and 17 figures

    Measured unsteady transonic aerodynamic characteristics of an elastic supercritical wing with an oscillating control surface

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    Transonic steady and unsteady aerodynamic data were measured on a large elastic wing in the NASA Langley Transonic Dynamics Tunnel. The wing had a supercritical airfoil shape and a leading-edge sweepback of 28.8 deg. The wing was heavily instrumented to measure both static and dynamic pressures and deflections. A hydraulically driven outboard control surface was oscillated to generate unsteady airloads on the wing. Representative results from the wind tunnel tests are presented and discussed, and the unexpected occurrence of an unusual dynamic wing instability, which was sensitive to angle of attack, is reported
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