Modeling unsteady turbulent flows over ripples: Reynolds-averaged Navier-Stokes equations (RANS) versus large-eddy simulation (LES)

In this paper we consider the problem of modeling a turbulent pulsating boundary layer over ripples. We compare the results of two modeling strategies, Wilcox's k - ω Reynolds-Averaged Navier-Stokes equations (RANS) and large-eddy simulation (LES) employing the Lagrangian dynamic eddy viscosity model. The geometry and parameters employed are relevant to nearshore oceanic flows, and the results are discussed in relation to the problem of sediment transport. Generally, RANS and LES agree well only with regard to the vertical profiles of the streamwise component of the velocity. Large discrepancies were found in all the other quantities considered (e.g., vertical velocity, turbulent kinetic energy, and Reynolds stress). In particular, RANS severely underpredicted the magnitude of the Reynolds stress and overpredicted the amplitude of the oscillations in the vertical velocity. We also found that often the trends exhibited by RANS and LES when the frequency and/or amplitude of the driving conditions was varied were at odds. Since comparison with available experiments indicates that LES is able to accurately model this kind of flows, we conclude that the RANS model is not appropriate to model the suspension and transport of sediment under conditions similar to the ones presented in this study

Turbulent convection of suspended sediments due to flow reversal

We investigate the ejection of sediments from the near-bed region of a pulsating boundary layer over a flat bottom. The boundary layer flows were generated using Large Eddy Simulation (LES) while the motion of individual particles was calculated using a modified version of the Maxey and Riley equation. The suspension rate of near-bed sediment particles sharply increases during decelerating flow phase and peaks near the time of local flow reversals. This suspension pattern of sediments was closely related to the near-bed turbulent vortex structures which evolve during a wave cycle. During period of maximum flow rate, the horizontally aligned vortex cores retarded settling of sediment particles. As the flow decelerates, vertically organized vortices induce an upward flux of particles. Vertical velocity fluctuations are strongest at the time of flow reversal, leading to maximum sediment suspension at this time. These results are shown to be incompatible with simple eddy-diffusivity models for sediment transport

Fast simultaneous detection of K-RAS mutations in colorectal cancer

<p>Abstract</p> <p>Background</p> <p><it>RAS </it>genes acquire the most common somatic gain-of-function mutations in human cancer, and almost all of these mutations are located at codons 12, 13, 61, and 146.</p> <p>Methods</p> <p>We present a method for detecting these <it>K-RAS </it>hotspot mutations in 228 cases of colorectal cancer. The protocol is based on the multiplex amplification of exons 2, 3 and 4 in a single tube, followed by primer extension of the PCR products using various sizes of primers to detect base changes at codons 12, 13, 61 and 146. We compared the clinicopathological data of colorectal cancer patients with the <it>K-RAS </it>mutation status.</p> <p>Results</p> <p><it>K-RAS </it>mutation occurred in 36% (83/228) of our colorectal cancer cases. Univariate analysis revealed a significant association between <it>K-RAS </it>mutation at codon 12 of exon 2 and poor 5-year survival (p = 0.023) and lymph node involvement (p = 0.048). Also, <it>K-RAS </it>mutation at codon 13 of exon 2 correlates with the size of the tumor (p = 0.03). Multivariate analysis adjusted for tumor size, histologic grade, and lymph node metastasis also indicated <it>K-RAS </it>mutations at codon 12 and 13 of exon 2 correlate significantly with overall survival (p = 0.002 and 0.025). No association was observed between codon 61 and 146 and clinicopathological features.</p> <p>Conclusion</p> <p>We demonstrated a simple and fast way to identify <it>K-RAS </it>mutation.</p

Does entropic force always imply the Newtonian force law?

We study the entropic force by introducing a bound $S \le A^{3/4}$ between entropy and area which was derived by imposing the non-gravitational collapse condition. In this case, applying a modified entropic force to this system does not lead to the Newtonian force law.Comment: 11 pages, version to appear in EPJ

In Situ Strain and Damage Monitoring of GFRP Laminates Incorporating Carbon Nanofibers under Tension

In this study, conductive carbon nanofibers (CNFs) were dispersed into epoxy resin and then infused into glass fiber fabric to fabricate CNF/glass fiber-reinforced polymer (GFRP) laminates. The electrical resistance and strain of CNF/GFRP laminates were measured simultaneously during tensile loadings to investigate the in situ strain and damage monitoring capability of CNF/GFRP laminates. The damage evolution and conduction mechanisms of the laminates were also presented. The results indicated that the percolation threshold of CNFs content for CNF/GFRP laminates was 0.86 wt % based on a typical power law. The resistance response during monotonic tensile loading could be classified into three stages corresponding to different damage mechanisms, which demonstrated a good ability of in situ damage monitoring of the CNF/GFRP laminates. In addition, the capacity of in situ strain monitoring of the laminates during small strain stages was also confirmed according to the synchronous and reversible resistance responses to strain under constant cyclic tensile loading. Moreover, the analysis of the resistance responses during incremental amplitude cyclic tensile loading with the maximum strain of 1.5% suggested that in situ strain and damage monitoring of the CNF/GFRP laminates were feasible and stable

Dynamical Behavior of dilaton in de Sitter space

We study the dynamical behavior of the dilaton in the background of three-dimensional Kerr-de Sitter space which is inspired from the low-energy string effective action. The perturbation analysis around the cosmological horizon of Kerr-de Sitter space reveals a mixing between the dilaton and other fields. Introducing a gauge (dilaton gauge), we can disentangle this mixing completely and obtain one decoupled dilaton equation. However it turns out that this belongs to the tachyon. The stability of de Sitter solution with J=0 is discussed. Finally we compute the dilaton absorption cross section to extract information on the cosmological horizon of de Sitter space.Comment: 11 pages, reference added and a version to appear in PL

Quantum Computing of Quantum Chaos in the Kicked Rotator Model

We investigate a quantum algorithm which simulates efficiently the quantum kicked rotator model, a system which displays rich physical properties, and enables to study problems of quantum chaos, atomic physics and localization of electrons in solids. The effects of errors in gate operations are tested on this algorithm in numerical simulations with up to 20 qubits. In this way various physical quantities are investigated. Some of them, such as second moment of probability distribution and tunneling transitions through invariant curves are shown to be particularly sensitive to errors. However, investigations of the fidelity and Wigner and Husimi distributions show that these physical quantities are robust in presence of imperfections. This implies that the algorithm can simulate the dynamics of quantum chaos in presence of a moderate amount of noise.Comment: research at Quantware MIPS Center http://www.quantware.ups-tlse.fr, revtex 11 pages, 13 figs, 2 figs and discussion adde

Hawking Temperature in Taub-NUT (A)dS spaces via the Generalized Uncertainty Principle

Using the extended forms of the Heisenberg uncertainty principle from string theory and the quantum gravity theory, we drived Hawking temperature of a Taub-Nut-(A)dS black hole. In spite of their distinctive natures such as asymptotically locally flat and breakdown of the area theorem of the horizon for the black holes, we show that the corrections to Hawking temperature by the generalized versions of the the Heisenberg uncertainty principle increases like the Schwarzschild-(A)dS black hole and give the reason why the Taub-Nut-(A)dS metric may have AdS/CFT dual picture.Comment: version published in General Relativity and Gravitatio

Observation of Two New N* Peaks in J/psi -> ppi−nˉp pi^- \bar n and pˉπ+n\bar p\pi^+n Decays

The $\pi N$ system in decays of $J/\psi\to\bar NN\pi$ is limited to be isospin 1/2 by isospin conservation. This provides a big advantage in studying $N^*\to \pi N$ compared with $\pi N$ and $\gamma N$ experiments which mix isospin 1/2 and 3/2 for the $\pi N$ system. Using 58 million $J/\psi$ decays collected with the Beijing Electron Positron Collider, more than 100 thousand $J/\psi \to p \pi^- \bar n + c.c.$ events are obtained. Besides two well known $N^*$ peaks at 1500 MeV and 1670 MeV, there are two new, clear $N^*$ peaks in the $p\pi$ invariant mass spectrum around 1360 MeV and 2030 MeV. They are the first direct observation of the $N^*(1440)$ peak and a long-sought "missing" $N^*$ peak above 2 GeV in the $\pi N$ invariant mass spectrum. A simple Breit-Wigner fit gives the mass and width for the $N^*(1440)$ peak as $1358\pm 6 \pm 16$ MeV and $179\pm 26\pm 50$ MeV, and for the new $N^*$ peak above 2 GeV as $2068\pm 3^{+15}_{-40}$ MeV and $165\pm 14\pm 40$ MeV, respectively