Resonance characteristics and polarization profile of partially poled P(VDF-TrFE) copolymer

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Exploring, Interpreting, and Applying Emotion-Driven Design in Brand Identity Development: A Design Student Case Study

This paper is a descriptive and qualitative case study of the emotional brand identity design process of an educational experience. The main goal concerns the exploration of methods, techniques, and approaches that visual communication design students use to interpret and apply emotion-driven design to two client-sponsored brand identity development projects—Center for Automotive Research and The Supreme Court of the Ohio. The participants in this study include twenty senior level students of a design program at a major university, the general public, the prospective users, and representatives from the client organizations. This study examines the design and application of a range of tools and methods for expressing, capturing, and applying emotion-driven experience to a brand identity development process from the design students’ perspectives during a 10-week academic quarter. In this case study, the emotional branding course outline utilized visual communication design problem-solving processes defined by four key design phases: Discovery Research, Design Definition, Design Concept, and Design Demonstration/Expression. The researchers of this study formulated a framework for the presentation of the various emotion-driven design tools based on adaptations of a reliable body of knowledge of pertinent literature. This study identifies emotion-driven design issues of concern to the participants and discusses the influences of these concerns on the design development of the selected projects

Efficacy of live attenuated seasonal and pandemic influenza vaccine in school-age children: a randomized controlled trial

Poster Presentation: SPA5 - How to Evaluate Vaccine Effectiveness and Efficacy?: abstract no. A508PBACKGROUND: A novel pandemic influenza A(H1N1) virus emerged in North America in early 2009 and rapidly spread worldwide. Monovalent pH1N1 vaccines were licensed later in 2009 based on preliminary studies demonstrating their immunogenicity and safety. In this study we report the efficacy of live attenuated monovalent pH1N1 vacc...postprin

Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii

<p>Abstract</p> <p>Background</p> <p>Atherosclerosis is a major cause of death in developed world. Atherosclerosis is characterized by low-density lipoprotein deposition in the arterial wall which ultimately begets the formation of lesions. Rupture of lesions finally leads to clinical events such as heart attack and stroke. Atherosclerosis is a complication associated with diabetes. In patients with diabetes, the risk of atherosclerosis is three to five folds greater than in non-diabetics. Our previous study showed that a herbal extract of <it>Radix Astragali, Radix Codonopsis </it>and <it>Cortex Lycii</it>, namely SR10, could improve glucose homeostasis both <it>in vitro </it>and <it>in vivo</it>. In this study, we want to further investigate the efficacy of SR10 in treating atherosclerosis.</p> <p>Method</p> <p>The inhibitory effect of SR10 on low-density lipoprotein oxidation was investigated using free radical-induced erythrocyte hemolysis model and copper ion-induced low-density lipoprotein oxidation model. Since vascular smooth muscle cell proliferation and migration are important processes in atherogenesis, we also examined the effect of SR10 in inhibiting these events.</p> <p>Results</p> <p>Our results showed that SR10 inhibited erythrocyte hemolysis with IC₅₀value at 0.25 mg/ml and significantly prolonged low-density lipoprotein oxidation <it>in vitro</it>. SR10 attenuated platelet derived growth factor-BB-induced vascular smooth muscle cell proliferation by promoting cell cycle arrest at G₀/G₁phase as well as inhibiting vascular smooth muscle cell migration.</p> <p>Conclusion</p> <p>The potential application of SR10 in treating atherosclerosis has been implied in this study. Animal model will be needed to further verify the efficacy of SR10 in future.</p

Measurement of Cosmic-ray Muons and Muon-induced Neutrons in the Aberdeen Tunnel Underground Laboratory

We have measured the muon flux and production rate of muon-induced neutrons at a depth of 611 m water equivalent. Our apparatus comprises three layers of crossed plastic scintillator hodoscopes for tracking the incident cosmic-ray muons and 760 L of gadolinium-doped liquid scintillator for producing and detecting neutrons. The vertical muon intensity was measured to be $I_{\mu} = (5.7 \pm 0.6) \times 10^{-6}$ cm$^{-2}$s$^{-1}$sr$^{-1}$. The yield of muon-induced neutrons in the liquid scintillator was determined to be $Y_{n} = (1.19 \pm 0.08 (stat) \pm 0.21 (syst)) \times 10^{-4}$ neutrons/($\mu\cdot$g$\cdot$cm$^{-2}$). A fit to the recently measured neutron yields at different depths gave a mean muon energy dependence of $\left\langle E_{\mu} \right\rangle^{0.76 \pm 0.03}$ for liquid-scintillator targets.Comment: 14 pages, 17 figures, 3 table

High angular resolution N-band observation of the silicate carbon star IRAS08002-3803 with the VLTI/MIDI instrument

We present the results of N-band spectro-interferometric observations of the silicate carbon star IRAS08002-3803 with the MID-infrared Interferometric instrument (MIDI) at the Very Large Telescope Interferometer (VLTI) of the European Southern Observatory (ESO). The observations were carried out using two unit telescopes (UT2 and UT3) with projected baseline lengths ranging from 39 to 47 m. Our observations of IRAS08002-3803 have spatially resolved the dusty environment of a silicate carbon star for the first time and revealed an unexpected wavelength dependence of the angular size in the N band: the uniform-disk diameter is found to be constant and ~36 mas (72 Rstar) between 8 and 10 micron, while it steeply increases longward of 10 micron to reach ~53 mas (106 Rstar) at 13 micron. Model calculations with our Monte Carlo radiative transfer code show that neither spherical shell models nor axisymmetric disk models consisting of silicate grains alone can simultaneously explain the observed wavelength dependence of the visibility and the spectral energy distribution (SED). We propose that the circumstellar environment of IRAS08002-3803 may consist of two grain species coexisting in the disk: silicate and a second grain species, for which we consider amorphous carbon, large silicate grains, and metallic iron grains. Comparison of the observed visibilities and SED with our models shows that such disk models can fairly -- though not entirely satisfactorily -- reproduce the observed SED and N-band visibilities. Our MIDI observations and the radiative transfer calculations lend support to the picture where oxygen-rich material around IRAS08002-3803 is stored in a circumbinary disk surrounding the carbon-rich primary star and its putative low-luminosity companion.Comment: 15 pages, 8 figures, accepted for publication in A&

Erratum to: Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response

published_or_final_versionSpringer Open Choice, 01 Dec 201

Imaging of detached shells around the carbon stars R Scl and U Ant through scattered stellar light

We present the first optical images of scattered light from large, detached gas/dust shells around two carbon stars, R Scl and U Ant, obtained in narrow band filters centred on the resonance lines of neutral K and Na, and in a Str. b filter (only U Ant). They confirm results obtained in CO radio line observations, but also reveal new and interesting structures. Towards R Scl the scattering appears optically thick in both the K and Na filters, and both images outline almost perfectly circular disks with essentially uniform intensity out to a sharp outer radius of 21". These disks are larger -- by about a factor of two -- than the radius of the detached shell which has been marginally resolved in CO radio line data. In U Ant the scattering in the K filter appears to be, at least partially, optically thin, and the image is consistent with scattering in a geometrically thin (3") shell (radius 43") with an overall spherical symmetry. The size of this shell agrees very well with that of the detached shell seen in CO radio line emission. The scattering in the Na filter appears more optically thick, and the image suggests the presence of at least one, possibly two, shells inside the 43" shell. There is no evidence for such a multiple-shell structure in the CO data, but this can be due to considerably lower masses for these inner shells. Weak scattering appears also in a shell which is located outside the 43" shell. The present data do not allow us to conclusively identify the scattering agent, but we argue that most of the emission in the K and Na filter images is to due to resonance line scattering, and that there is also a weaker contribution from dust scattering in the U Ant data. Awaiting new observational data, our interpretation must be regarded as tentative.Comment: 14 pages, 11 figures, to be published in A&