Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

Nicotinic regulation of hematopoiesis

Chronic activation of the sympathetic nervous system (SNS) contributes to increased myelopoiesis. Since nicotine activates the SNS, chronic nicotine consumption may also increase myelopoiesis. This is relevant to human health outcomes because myelopoiesis contributes to the progression of atherosclerosis and cardiovascular disease. To address this, mice were provided high dose nicotine in drinking water for two and three weeks, and leukocyte production and distribution were assessed. Nicotine supplementation for two weeks did not alter the production or distribution of leukocytes, but three weeks of nicotine increased hematopoietic progenitor proliferation in the spleen and mildly increased leukocyte counts in the spleen but not blood. Next, the sympathomimetic drug guanethidine was used to assess the effect of SNS inhibition during nicotine exposure. In this study, guanethidine did not influence leukocyte distribution or production in mice treated with nicotine. Collectively, three weeks of nicotine supplementation enhanced splenic hematopoiesis without meaningfully increasing the systemic leukocyte supply.U of I OnlyAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD syste

The Shortcomings of COVID-19 Testing in Ecuador: Time to Incentivize Research and Innovation

The COVID-19 pandemic hit Ecuador severely. The country caught the attention of international media due to its high death toll and overwhelmed healthcare system. The clinical diagnostics system was rapidly overloaded, and the import of PCR tests was delayed. The case of Ecuador illustrates how middle-income countries rely heavily on the importation of biotechnological products for their healthcare systems. The Ecuadorian experience during the COVID-19 pandemic serves as a call for the formation of policies for the development of the biotechnological industry

Congreso Internacional euro-latinoamericano y caribeño: "La necesaria creación de un espacio de un espacio cultural birregional: valores, principios y propuestas"

Actas del Congreso Internacional euro-latinoamericano y caribeño: "La necesaria creación de un espacio de un espacio cultural birregional: valores, principios y propuestas" celebrado en el Monasterio de Yuste (Cáceres, España) del 22 al 24 de septiembre de 2021.El documento "Algunas miradas a la cooperación internacional en materia de cultura de 2000 a 2021 de España: Caso Colombia y Cuba / Laurita Botero Botero y Cecilia Yadira Benítez" fue realizado en el marco del proyecto de investigación y desarrollo PID 2020 No. 80020190100051UR “Agendas y actores multinivel de la cooperación internacional argentina: realizaciones y proyecciones en el primer cuarto de siglo XXI (2000-2025) de la Universidad Nacional de Rosario (Argentina), dirigido por la Dra Myriam Colacrai.Presentación / Adrián Bonilla y Cástor Díaz Barrado (p. V). -- Introducción / Diego Durán Cruz (p. VI). -- La cooperación cultural Iberoamericana. Mosaico de perspectivas, agendas y actores involucrados / Miryam Colacrai (pp. 1-5). -- Cooperación cultural: nuevos contextos y potencialidades en el ámbito birregional Europa-América Latina / Mónica García Alonso (pp. 6-10). -- La implementación de la Agenda 2030 en el ámbito cultural / Carlos R. Fernández Liesa (p. 11). -- Una visión desde Cuba sobre la necesaria creación de un espacio cultural eurolatinoamericano: valores, principios y propuestas / Juan Mendoza Díaz (pp. 12-15). -- Minorías étnicas y Constitución política de 1991 en Colombia / Roberto González Arana (pp. 16-20). -- Género y diversidad cultural: elementos clave para el fortalecimiento cultural en América Latina / Diana M. Verdiales López (pp. 21-25). -- Las expresiones del racismo moderno y racismo cordial promueven la vulneración de derechos de las minorías afrodescendientes en Colombia. Ideas para la discusión / Ivonne Samira Molinares Guerrero (pp. 26-30). -- La falta de protagonismo de la cultura en la Agenda 2030 / Sagrario Morán Blanco (pp. 31-34). -- La Carta Cultural Iberoamericana, las industrias culturales y creativas / Ana Idalia Castellanos (pp. 35-39). -- La Carta Cultural Iberoamericana: su utilidad en la cooperación Unión Europea-CELAC / Harold Bertot Triana y Elena C. Díaz Galán (pp. 40-43). -- Relaciones culturales UE-LAC: EUNIC y sus proyectos con Latinoamerica y El Caribe / Cristina Peregrina Leyva (pp. 44-59). -- Algunas miradas a la cooperación internacional en materia de cultura de 2000 a 2021 de España: Caso Colombia y Cuba / Laurita Botero Botero y Cecilia Yadira Benítez (pp. 60-70). -- El cine como expresión cultural imprescindible para la educación en Derechos Humanos en el espacio euro-latinoamericano / Andrés Felipe Ricaurte Pazmiño (pp. 71-82). -- Lo que todo iberoamericano debe conocer sobre Iberoamérica: un currículo educativo integral orientado a un pasado, presente y futuro conjunto / Izan Chalen Paredes (pp. 83-96). -- El papel de las lenguas ibéricas en la creación de un espacio iberoamericano del conocimiento / Javier Abellán (pp. 97-110). -- La cooperación cultural en el espacio eurolatinoamericano como respuesta a los retos globales del siglo XXI / Edith Ruvalcaba Galindo (pp. 111-132)

Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale