Detection of contagious caprine pleuropneumonia in East Turkey

A study was implemented to investigate the presence of contagious caprine pleuropneumonia (CCPP) in East Turkey. This study was based on clinical surveillance in the field, surveillance at regional slaughterhouses and regular submission of suspected lesions to regional laboratories. The results showed that the agent of CCPP, Mycoplasma capricolum subspecies capripneumoniae (Mccp), could be detected by culture and specific polymerase chain reaction from 37.5% (12/32) of lung samples taken from goats of ten different herds. This agent was also isolated from two of 13 sheep samples (one from the lung and the other from a nasal swab). Mycoplasma capricolum subsp. capripneumoniae was isolated in pure culture and characterised at a finer molecular level. The East Turkish isolate was found to be closely related to another strain of Turkish origin, as well as to Mccp strains isolated in Tunisia. The isolation of Mccp from sheep lung lesions brings the strict host-specificity of this pathogen into question. It may also indicate that Mccp presents a risk for wildlife in the region. Such results, the authors believe, demonstrate that adequate risk assessments should be undertaken in Turkey and neighbouring countries. (Résumé d'auteur

unreinforced masonry buildings

A recent earthquake of M=4.9 occurred on 29 October 2007 in C, ameli, Denizli, which is located in a seismically active region at southwest Anatolia, Turkey. It has caused extensive damages at unreinforced masonry buildings like many other cases observed in Turkey during other previous earthquakes. Most of the damaged structures were non-engineered, seismically deficient, unreinforced masonry buildings. This paper presents a site survey of these damaged buildings. In addition to typical masonry damages, some infrequent, event-specific damages were also observed. Reasons for the relatively wide spread damages considering the magnitude of the event are discussed in the paper

Search for the anomalous ZZZZZZ and ZZγZZ\gamma gauge couplings through the process e+e−→ZZe^+e^- \to ZZ with unpolarized and polarized beams

This work offers the constraints on the anomalous neutral triple gauge couplings (aNTGC) for the process $e^+e^- \to ZZ$ at the CLIC with $\sqrt{s}=3$ TeV. The realistic CLIC detector environments and their effects are considered in our analysis. The study is planned for the decays of producted $Z$ bosons to a pair of charged leptons (electrons or muons) and neutrino pairs. The bounds on the aNTGCs defining $CP$-conserving $C_{\widetilde{B}W}/{\Lambda^4}$ coupling and three $CP$-violating $C_{WW}/{\Lambda^4}$, $C_{BW}/{\Lambda^4}$, and $C_{BB}/{\Lambda^4}$ couplings are obtained. Also, the effects and advantages of polarization for incoming electron beams in these calculations are investigated.Comment: 21 pages, 14 figure

Graphene and Related Materials for the Internet of Bio-Nano Things

Internet of Bio-Nano Things (IoBNT) is a transformative communication framework, characterized by heterogeneous networks comprising both biological entities and artificial micro/nano-scale devices, so-called Bio-Nano Things (BNTs), interfaced with conventional communication networks for enabling innovative biomedical and environmental applications. Realizing the potential of IoBNT requires the development of new and unconventional communication technologies, such as molecular communications, as well as the corresponding transceivers, bio-cyber interfacing technologies connecting the biochemical domain of IoBNT to the electromagnetic domain of conventional networks, and miniaturized energy harvesting and storage components for the continuous power supply to BNTs. Graphene and related materials (GRMs) exhibit exceptional electrical, optical, biochemical, and mechanical properties, rendering them ideal candidates for addressing the challenges posed by IoBNT. This perspective article highlights recent advancements in GRM-based device technologies that are promising for implementing the core components of IoBNT. By identifying the unique opportunities afforded by GRMs and aligning them with the practical challenges associated with IoBNT, particularly in the materials domain, our aim is to accelerate the transition of envisaged IoBNT applications from theoretical concepts to practical implementations, while also uncovering new application areas for GRMs

A Patient with Proopiomelanocortin Deficiency: An Increasingly Important Diagnosis to Make

Proopiomelanocortin (POMC) deficiency is a rare monogenic disorder with early-onset obesity. Investigation of this entity have increased our insight into the important role of the leptin-melanocortin pathway in energy balance. Here, we present a patient with POMC deficiency due to a homozygous c.206delC mutation in the POMC gene. We discuss the pathogenesis of this condition with emphasis on the crosstalk between hypothalamic and peripheral signals in the development of obesity and the POMC-melanocortin 4 receptors system as a target for therapeutic intervention

Effects of Nigella sativa seeds and certain species of fungi extracts on number and activation of dural mast cells in rats

In this study, we aimed to investigate the effects of Nigella sativa seeds and certain species of fungi extracts on the number and degranulation states of dural mast cells in rats. Rats were fed ad libitum with normal tap water or tap water with extract of N. sativa seed, Ramaria condensata, Lactarius salmonicolor, Lactarius piperatus, and Tricholoma terreum for 3 days. Mast cells in dura mater were counted and evaluated in terms of granulation and degranulation states. Compound 48/80, a mast cell degranulating agent, and T. terreum significantly increased the percent of degranulated mast cells in dura mater, respectively (p < 0.01 and p < 0.05). Moreover, T. terreum causes a significant increase in the total number of mast cells (p < 0.05). N. sativa significantly inhibited mast cell degranulation induced by both the compound 48/80 and T. terreum (p < 0.05), and significantly decreased the mast cell numbers increased by T. terreum (p < 0.05). Our results suggested that T. terreum following ingestion can contribute to headaches like migraine via dural mast cell degranulation and N. sativa may be able to exert analgesic and anti-inflammatory effects by stabilizing dural mast cells. However, investigation is needed to determine the ingredients of N. sativa that may be responsible for these beneficial effects

Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in various lung diseases

Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a new method for the diagnosis and staging of lung disease, and its use is increasing worldwide. It has been used as a means of diagnosing lung cancer in its initial stages, and there are data supporting its use for the diagnosis of benign lung disease. The aim of this study was to share our experience with EBUS-TBNA and discuss its diagnostic value. Methods: We retrospectively analyzed the results related to 159 patients who underwent EBUS-TBNA at our pulmonary medicine clinic between 2010 and 2013. We recorded the location and size of lymph nodes seen during EBUS. Lymph nodes that appeared to be affected on EBUS were sampled at least twice. We recorded the diagnostic results of EBUS-TBNA and (for cases in which EBUS-TBNA yielded an inconclusive diagnosis) the final diagnoses after further investigation and follow-up. Results: We evaluated 159 patients, of whom 89 (56%) were male and 70 (44%) were female. The mean age was 54.6 ± 14.2 years among the male patients and 51.9 ± 11.3 years among the female patients. Of the 159 patients evaluated, 115 (84%) were correctly diagnosed by EBUS. The diagnostic accuracy of EBUS-TBNA was 83% for benign granulomatous diseases and 77% for malignant diseases. Conclusions: The diagnostic value of EBUS-TBNA is also high for benign pathologies, such as sarcoidosis and tuberculosis. In patients with mediastinal disorders, the use of EBUS-TBNA should be encouraged, primarily because it markedly reduces the need for mediastinoscopy

FREQUENCY RATIO ASSESSMENT FOR LANDSLIDES TRIGGERED BY 6 FEBRUARY 2023 KAHRAMANMARAS TURKIYE EARTHQUAKES BETWEEN GOLBASI AND ERKENEK

Landslides triggered by earthquakes are significant geological hazards that can have devastating consequences, posing risks to human lives, infrastructure, and the environment. These seismic events may cause the instability of slopes and result in the displacement of soil and rock materials, leading to landslides. It is crucial to understand the characteristics and mechanisms of earthquake-triggered landslides in order to effectively manage and mitigate their associated risks. The number of landslides triggered by the 2023 Kahramanmaraş earthquakes (with magnitudes of 7.7 and 7.6) was over three thousand and their destructive effects were also devastating as secondary hazards. This study aims to examine the characteristics of landslides using the frequency ratio (FR) model. A landslide susceptibility map (LSM) was also produced using the output. For this purpose, in this study, we derived landslides triggered by the earthquakes in a part of the earthquake-affected region, between Golbasi town of Adiyaman and Erkenek village of Malatya covering an area with a size of 625 km2. The study utilized a landslide inventory that was manually delineated by visual interpretation based on pre-event and post-event. These associations can serve as a foundation for the application of various data-driven machine learning techniques. The findings of this study will contribute to the development of accurate LSMs, providing crucial insights into the behavior of earthquake-triggered landslides