Protective Effect of Cup Therapy Model in Rats on Epileptic Seizures by Determination of Different Anatomic Region

[Abstract Not Available]WOS:00053241580014

Protective Effect of Cup Therapy Model in Rats on Epileptic Seizures by Determination of Different Anatomic Region

[Abstract Not Available]WOS:00053241580014

Evaluation of the Protective Effect of the Cup Therapy on the Epileptic Seizure in Rats

Objective: Cup therapy has an important place in traditional and complementary medicine applications. The purpose of our study, this is the first time to investigate the protective effect of cup therapy in rats on experimentally generated epileptic seizures in new rat modeling created by different anatomic regions. Methods: A total of 42 Wistar albino rats were randomly divided into 6 groups (n:7). The new dry cup was applied to the G1 group, and the new wet cup model was applied to the G2. In the G3 group, an epilepsy model (PTZ, 35 mg / kg) was created and diazepam (2.5 mg / kg) was given to G4. Dry cup and wet cup models were applied to the G5 and G6 groups, respectively. 24 hours after the cupping therapies, the rats were injected with PTZ and the epilepsy behavior scores of the rats in all groups were recorded for 20-30 minutes. Results: In the 'Open Area' and 'Elevated Plus Maze' tests, there was no behavioral difference between the cup therapy group and the control group (p > 0.05). Given all the parameters, the G4 group significantly reduces the seizure compared to other groups (p < 0.05). There is a significant difference in G2, G5 and G6 groups compared to G3 in the phases parameter (p < 0.05). Conclusions: In this study, the new wet cup therapy (G2), which was applied for the first time, had a protective effect on seizures. G2, G5 and G6 groups are observed to suppress seizures compared to G3. Our findings are expected to contribute greatly to animal model analysis in the future.WOS:00070904020001

Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome in a Child With Klinefelter Syndrome.

Klinefelter syndrome is characterized by gynecomastia, hypogonadism, small testes, elevated levels of follicle-stimulating hormone and an extra X chromosome (ie, 47,XXY).1 These patients tend to have an increased risk of developing male breast cancer and mediastinal germ cell tumors.2,3 Hematologic malignancies including acute or chronic leukemia are also observed in these patients,4 but only a few case reports with Klinefelter syndrome who developed myelodysplastic syndrome (MDS) were published.4–7Wo

Baby-skin care habits from different socio-economic groups and its impact on the development of atopic dermatitis

Skin care practices of children vary among communities and are based on experience, tradition and culture. It was aimed to determine the baby-skin care approaches of mothers from three different socio-economic groups and its effect on the development of atopic dermatitis. The study comprised mothers with children under 2 years of age from three different socioeconomic groups in Istanbul in the first half of 2014. A questionnaire with 38 items related to demographic variables, feeding habits, and baby-skin care were distributed to the mothers and asked to fill at sight. The study comprised of 207 children with 69 from lower socio-economic group, 92 children from group middle socio-economic and 46 children from higher socio-economic group. Mean age was 8.48, 8.74, and 10.98 months, respectively. Atopic dermatitis was reported in 19% of the children from higher socio-economic and 9% of the children in other two groups each. The proportion of using no care products after bath was found to be lower in children with atopic dermatitis from all three groups. The proportion of using wet wipes for diaper care was significantly lower in children with atopic dermatitis in comparison to children without atopic dermatitis. Atopic dermatitis was more common among children from higher socioeconomic group and skin care after bath seems to be an important factor in the development of atopic dermatitis

RESULTS OF TETANUS VACCINATION IN SARCOIDOSIS

Background and Objective: Cellular immunity abnormalities are associated with sarcoidosis. Normal cellular immunity is required for adequate humoral immunity; therefore, a decreased humoral immune response is possible in patients with sarcoidosis. We evaluated humoral immunity by vaccinating patients with sarcoidosis against tetanus. Patients and method: We screened 60 patients with sarcoidosis (42 females, average age 39 +/- 11 years) and 40 healthy subjects as a control (23 females, average age 38 +/- 9 years). Of the 51 sarcoidosis patients and 33 controls that did not have sufficient tetanus antibody titers, 48 patients and 31 controls agreed to be vaccinated and were included in the vaccination program. Blood serum samples were collected from the subjects before and after vaccination and evaluated for tetanus toxoid IgG antibodies with an enzyme-linked immunosorbent assay (ELISA). Results: As a result of the vaccination, 24 of the sarcoidosis patients (50%) and 7 of the controls (23%) had insufficient antibody responses (p = 0.019). No relationship was found in sarcoidosis patients between the rate of having sufficient antibody levels and disease duration, activation state, and radiographic staging of the disease. Conversely, mean lymphocyte numbers were significantly lower in patients with insufficient tetanus antibody levels (p = 0.013). Conclusion: Tetanus vaccinations in sarcoidosis patients are less effective than in healthy controls, suggesting that patients with sarcoidosis have a hyporesponsive humoral immune system