Inscripciones de la Villa de Alcántara, de Alcalá de los Ríos y ladrillos con crismón hallados en Ronda.

Edición de dos manuscritos epigráficos de Alcántara cuyo autor fue Francisco A. Forner, pero proceden de sendas copias realizadas en Andalucía durante la estancia de J. P. Forner en Sevilla. --------Editing Alcántara two epigraphic manuscripts authored by F. A. Forner, but come from copies made in Andalusia during the stay of J.P. Forner in Seville

Statistical Communication Theory

Contains reports on four research projects

Drought and Forest Decline in the Iberian Peninsula: A Simple Explanation for a Complex Phenomenom?

Different episodes of forest decline have been reported in several areas of the Northern Hemisphere during the 20th century. The explanation of this process included anthropogenic (air pollution), biotic (pathogens) and climatic factors. Among the climatic factors, the effects of acute or chronic droughts have been the most common explanation for the massive dieback observed. In the Iberian Peninsula, besides the pathogenic explanation which gives a paramount relevance to the fungus Phytophtora cinnamomi in many situations, the role of an increment in aridity (chronic) or the consequences of severe droughts (acute) have been empirically supported. The evident synchronism between forest decline and abnormally adverse climatic conditions, in addition to the reversibility of the process when precipitation intensity increased, are two major arguments for supporting the climatic involvement in the phenomenon. Nevertheless, the two most affected species in the episodes of oak decline in the Iberian Peninsula were Quercus ilex and Q. suber, which are representatives of the so called Mediterranean woody flora and which have been considered as more drought resistant than the temperate oak species that co-occur in this territory. The climatic complexity ofthe Iberian Peninsula, the many mechanisms for coping with water stress that have been described within the sclerophyllous Mediterranean flora and the effects of human management partially explain this paradox. Other forest species have also been affected by massive decline. Pinus sylvestris and Abies alba, which have their southern distribution limit in the mountain ranges of the Iberian Peninsula, are two examples of this situation. Both cases, besides the inmediate effects of some climatic perturbations, need the incorporation of different predisposing factors – mainly historical aspects to obtain a complete image of the process

Statistical Communication Theory

Contains reports on five research projects

Tratamientos fungicidas para el control del chancro causado por Diplodia sp. en alcornoque

En este trabajo se presentan los resultados de un ensayo de fungicidas para el control de daños de Diplodia sp. sobre alcornoque. Los productos ensayados han sido: oxicloruro de cobre, folpet y benomilo. El análisis en laboratorio de las muestras recogidas corroboró la abundante presencia de Diplodia sp. en la parcela de San Carlos del Tiradero (Cádiz). Los árboles tratados con benomilo y benomilo + oxicloruro de cobre presentaban menor número de chancros que los demás, aunque no han existido diferencias significativas entre los distintos tratamientos y los árboles testigos. En ambas parcelas, la severidad de los síntomas resultó significativamente menor en los árboles tratados con benomilo + oxicloruro de cobre. Los resultados han puesto de manifiesto la eficacia de los tratamientos de benomilo y benomilo + oxicloruro de cobre para el control de daños de Diplodia sp

Approach and management of diaphragmatic paralysis in adults

3 years ago, 38-year-old male, with no relevant personal pathological history, began to present exertional dyspnea, gastroesophageal reflux, retrosternal pyrosis, dyspepsia and postprandial abdominal distension after a traffic accident. A study protocol was initiated, where cabinet studies documented elevation of the left hemidiaphragm was documented. A minimally invasive approach was performed with the finding of elevation of the left hemidiaphragm of approximately 8 cm in relation to the contralateral diaphragm without evidence of paraesophageal hernia. Mayo type left diaphragmatic plication was performed with non-absorbable suture (polypropylene 1) without complications. With favorable evolution, he started the oral route 8 hours postoperatively, and was discharged 48 hours after surgery due to clinical improvement and without gastroesophageal reflux. Surgical plication of the affected hemidiaphragm is successful in carefully selected patients with severe symptoms thought to be due to unilateral diaphragmatic paralysis. Studies demonstrate improvement in several parameters, including lung and respiratory muscle function, exercise endurance, blood gas exchange, and possibly dyspnea

Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle

Neospora caninum is one of the main causes of transmissible abortion in cattle. Intraspecific variations in virulence have been widely shown among N. caninum isolates. However, the molecular basis governing such variability have not been elucidated to date. In this study label free LC-MS/MS was used to investigate proteome differences between the high virulence isolate Nc-Spain7 and the low virulence isolate Nc-Spain1H throughout the tachyzoite lytic cycle. The results showed greater differences in the abundance of proteins at invasion and egress with 77 and 62 proteins, respectively. During parasite replication, only 19 proteins were differentially abundant between isolates. The microneme protein repertoire involved in parasite invasion and egress was more abundant in the Nc-Spain1H isolate, which displays a lower invasion rate. Rhoptry and dense granule proteins, proteins related to metabolism and stress responses also showed differential abundances between isolates. Comparative RNA-Seq analyses during tachyzoite egress were also performed, revealing an expression profile of genes associated with the bradyzoite stage in the low virulence Nc-Spain1H isolate. The differences in proteome and RNA expression profiles between these two isolates reveal interesting insights into likely mechanisms involved in specific phenotypic traits and virulence in N. caninum. Significance The molecular basis that governs biological variability in N. caninum and the pathogenesis of neosporosis has not been well-established yet. This is the first study in which high throughput technology of LC-MS/MS and RNA-Seq is used to investigate differences in the proteome and transcriptome between two well-characterized isolates. Both isolates displayed different proteomes throughout the lytic cycle and the transcriptomes also showed marked variations but were inconsistent with the proteome results. However, both datasets identified a pre-bradyzoite status of the low virulence isolate Nc-Spain1H. This study reveals interesting insights into likely mechanisms involved in virulence in N. caninum and shed light on a subset of proteins that are potentially involved in the pathogenesis of this parasite

Effect of exogenous xylanase on rumen in vitro gas production and degradability of wheat straw

In Mongolia, the low and seasonal yield of native pastures causes a feed gap between the annual pasture provision and the requirements of grazing ruminants. Therefore, there is a growing need to improve the feeding value of locally available resources such as wheat straw for supplementary feeding. Wheat straw constitutes an important source of roughage for ruminants. It typically contain more than 70% neutral detergent fiber (NDF) on a dry matter (DM) basis, with less than 40% total digestive tract digestibility of the NDF, even under ideal feeding conditions (NRC 2001).The objective of this study was to determine effects of xylanase on in vitro gas production (GP) and in sacco degradability of wheat straw. Rumen fluid was obtained from three Mongolian native goats fitted with permanent rumen cannulas. The trial consisted of five doses (0, 0.5, 1.0, 1.5, 2.0 μL/g of substrate) of a commercial xylanase (Dyadic® xylanase PLUS, Dyadic International, Inc., Jupiter, FL, USA). For the in sacco degradability, different levels of xylanase enzyme were added directly onto 2 g of wheat straw in nylon bags and incubated in the rumen for 3, 6, 12, 24 and 48 h to estimate degradability of wheat straw. Total GP increased (P < 0.001) at all times of incubation at intermediate levels of xylanase. Methane production had a similar pattern at 3 and 12 h of incubation; increased linearly at 24 h of incubation, and was unaffected at 6 and 48 h of incubation. Rumen NH3-N concentration increased linearly at 3 h and the highest values were observed with intermediate enzyme levels. All ruminal volatile fatty acids increased linearly with intermediate levels of the fibrolytic enzyme. The in sacco rate of dry matter degradation decreased linearly (P = 0.020) with increasing enzymes. Intermediate levels of xylanase improved rumen kinetic fermentation and degradability. The outcome of this research indicated that the application of xylanase enzyme could improve in vitro GP fermentation of wheat straw

Effect of polyethylene glycol on in vitro gas production kinetics of Prosopis cineraria leaves at different growth stages

The aim of this experiment was to determine the effect of polyethylene glycol (PEG) on in vitro gas production (GP) kinetics of Prosopis cineraria leaves at different growth stages. The contents of total phenol (TPH), total tannin (TT) and condensed tannin (CT) were determined. Effects on in vitro organic matter digestibility (OMD), metabolisable energy (ME) and effective dry matter digestibility were assessed by PEG tannin bioassay. No significant differences (P>0.05) were observed for TPH content; however, the stage of flowering had the highest (P0.05) were observed between the growth stage and PEG addition for in vitro GP and its parameters. Addition of PEG increased (P<0.05) GP, OMD and ME in all stages. In conclusion, adding PEG to P. cineraria leaves can improve their nutritive value and could be considered as a potential feed for ruminants