The Sacred and the Political: Exploration on Mimesis, Violence and Religion

What is the relationship between the sacred and the political, transcendence and immanence, religion and violence? And how has this complex relation affected the history of Western political reason? In this volume an international group of scholars explore these questions in light of mimetic theory as formulated by René Girard (1923-2015), one of the most original thinkers of our time. From Aristotle and his idea of tragedy, passing through Machiavelli and political modernity, up to contemporary biopolitics, this work provides an indispensable guide to those who want to assess the thorny interconnections of sacrality and politics in Western political thought and follow an unexplored yet critical path from ancient Greece to our post-secular condition. While looking at the past, this volume also seeks to illuminate the future relevance of the sacred/secular divide in the so-called 'age of globalization'

Religion and Political Form: Carl Schmitt’s Genealogy of Politics as Critique of Habermas’s Post-secular Discourse

Jürgen Habermas's post-secular account is rapidly attracting attention in many fields as a theoretical framework through which to reconsider the role of religion in contemporary societies. This work seeks to go beyond Habermas's conceptualisation by placing the post-secular discourse within a broader genealogy of the relationships between space, religion, and politics. Drawing on the work of Carl Schmitt, the aim of this article is to contrast the artificial separation between private and public, religious and secular, state and church, and the logic of inclusion/exclusion on which modernity was established. Revisiting this genealogy is also crucial to illustrating, in light of Schmitt's political theory, the problems underlying Habermas's proposal, emphasising its hidden homogenising and universalist logic in an attempt to offer an alternative reflection on the contribution of religious and cultural pluralism within Western democracies

Cognitive dimensions of predator responses to imperfect mimicry?

Many palatable insects, for example hoverflies, deter predators by mimicking well-defended insects such as wasps. However, for human observers, these flies often seem to be little better than caricatures of wasps – their visual appearance and behaviour are easily distinguishable. This imperfect mimicry baffles evolutionary biologists, because one might expect natural selection to do a more thorough job. Here we discuss two types of cognitive processes that might explain why mimics distinguishable mimics might enjoy increased protection from predation. Speed accuracy tradeoffs in predator decision making might give imperfect mimics sufficient time to escape, and predators under time constraint might avoid time-consuming discriminations between well-defended models and inaccurate edible mimics, and instead adopt a “safety first” policy of avoiding insects with similar appearance. Categorization of prey types by predators could mean that wholly dissimilar mimics may be protected, provided they share some common property with noxious prey

Inconsistency in serial choice decision and motor reaction times dissociate in younger and older adults

Intraindividual variability (inconsistency) in reaction time (RT) latencies was investigated in a group of younger (M = 25.46 years) and older (M = 69.29 years) men. Both groups performed 300 trials in 2-, 4-, and 8-choice RT conditions where RTs for decision and motor components of the task were recorded separately. A dissociation was evident in that inconsistency was greater in older adults for decision RTs when task demands relating to the number of choices and fatigue arising from time-on-task were high. For younger persons, a weak trend toward greater inconsistency in motor RTs was evident. The results are consistent with accounts suggesting that inconsistency in neurobiological mechanisms increases with age, and that attentional lapses or fluctuations in executive control contribute to RT inconsistency

Interactions between anxiety subtypes, personality characteristics, and emotional regulation skills as predictors of future career outcomes

Trait anxiety, anxious arousal, rejection sensitivity, and implicit feelings of rejection in adolescence were examined as predictors of long-term career performance, satisfaction, success, and ambition. Personality traits such as conscientiousness and grit, as well as coping and emotion regulation skills were analyzed as potential moderating variables. Anxious arousal and rejection sensitivity were predicted to be more strongly associated with negative career outcomes, and coping skills were predicted to be more effective in diminishing negative consequences of anxiety. Multi-reporter data were obtained from 184 teens at ages 17-19 and 26-27, and 27-29. Trait anxiety was the only anxiety variable to correlate significantly with negative occupational outcomes. Trait anxiety predicted lower ambition, job satisfaction, and career satisfaction after controlling for the effects of gender and income in hierarchical regressions. Trait anxiety, as well as anxious arousal, had multiple significant interactions with occupational outcomes. Coping skills had main effects with several occupational outcomes including ambition, work performance, and job satisfaction after controlling for each subtype of anxiety; however, no significant interactions were found. Instead, emotion regulation played an important role in four interactions between anxiety and occupational outcomes. Limitations and implications of the findings are discussed

Proapoptotic activity of new glutathione S-transferase inhibitors

Selected 7-nitro-2,1,3-benzoxadiazole derivatives have been recently found very efficient inhibitors of glutathione S-transferase (GST) PI-1,(5) an enzyme which displays antiapoptotic activity and is also involved in the cellular resistance to anticancer drugs. These new inhibitors are not tripeptide glutathione-peptidomimetic molecules and display lipophylic properties suitable for crossing the plasma membrane. In the present work, we show the strong cytotoxic activity of these compounds in the following four different cell lines: K562 (human myeloid leukemia), HepG2 (human hepatic carcinoma), CCRF-CEM (human T-lymphoblastic leukemia), and GLC-4 (human small cell lung carcinoma). The LC50 values are in the micromolar/submicromolar range and are close to the ICs values obtained with GSTPI-1, suggesting that the target of these molecules inside the cell is indeed this enzyme. The cytotoxic mechanism of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, the most effective GSTPI-1 inhibitor, has been carefully investigated in leukemic CCRF-CEM and K562 cell lines. Western blot and immunoprecipitation analyzes have shown that 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanoI promotes in both cell lines the dissociation of the GSTPI-1 in a complex with c-jun NH2-terminal kinase (JNK). This process triggers a reactive oxygen species (ROS) -independent activation of the JNK-mediated pathway that results in a typical process of apoptosis. Besides this main pathway, in K562 cells, a ROS-mediated apoptosis partially occurs (about 30%) which involves the p38(MAPK) signal transduction pathway. The low concentration of this new compound needed to trigger cytotoxic effects on tumor cells and the low toxicity on mice indicate that the new 7-nitro-2,1,3-benzoxadiazole derivatives are promising anticancer agents