Calibration of QM-MOURA three-axis magnetometer and gradiometer

Abstract. MOURA instrument is a three-axis magnetometer and gradiometer designed and developed for Mars MetNet Precursor mission. The initial scientific goal of the instrument is to measure the local magnetic field in the surroundings of the lander i.e. to characterize the magnetic environment generated by the remanent magnetization of the crust and the superimposed daily variations of the field produced either by the solar wind incidence or by the thermomagnetic variations. Therefore, the qualification model (QM) will be tested in representative scenarios like magnetic surveys on terrestrial analogues of Mars and monitoring solar events, with the aim to achieve some experience prior to the arrival to Mars. In this work, we present a practical first approach for calibration of the instrument in the laboratory; a finer correction after the comparison of MOURA data with those of a reference magnetometer located in San Pablo de los Montes (SPT) INTERMAGNET Observatory; and a comparative recording of a geomagnetic storm as a demonstration of the compliance of the instrument capabilities with the scientific objectives

Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis

A lot of studies have been carried out on Saccharomyces cerevisiae, an yeast with a predominant fermentative metabolism under aerobic conditions, which allows exploring the complex response induced by oxidative stress. S. cerevisiae is considered a eukaryote model for these studies. We propose Kluyveromyces lactis as a good alternative model to analyse variants in the oxidative stress response, since the respiratory metabolism in this yeast is predominant under aerobic conditions and it shows other important differences with S. cerevisiae in catabolic repression and carbohydrate utilization. The knowledge of oxidative stress response in K. lactis is still a developing field. In this article, we summarize the state of the art derived from experimental approaches and we provide a global vision on the characteristics of the putative K. lactis components of the oxidative stress response pathway, inferred from their sequence homology with the S. cerevisiae counterparts. Since K. lactis is also a well-established alternative host for industrial production of native enzymes and heterologous proteins, relevant differences in the oxidative stress response pathway and their potential in biotechnological uses of this yeast are also reviewed

Amino acids content in 'Tempranillo' must from three soil types over four vintages

Amino acids are the main grape nitrogen compounds and the principal source of N for yeasts, being precursors of several volatile compounds. Therefore, N compound concentrations in musts can affect sensorial characteristics of wines. The aim of this study was to analyse the influence of N-NO3- and N-NH4+ contents from different soils on profile and content of amino acids in 'Tempranillo' grapes. In order to determine this soil influence on must quality, three plots were selected in AOC Rioja, classified as Fluventic Haploxerepts, Typic Calcixerepts, and Petrocalcic Palexerolls. The results showed that amino acids and yeast assimilable nitrogen (YAN) content allowed us to differentiate samples from the three soils, and in each soil type, samples of each season. In general, must contents of total amino acids and some of them, as alanine, threonine, and tyrosine, were more influenced by soil type; YAN, proline, histidine, serine, and glycine concentrations mainly depended on the interaction soil-vintage. In conclusion, free amino acids concentration could be a tool to differentiate musts coming from different soils

Acoustic estimation of abundance and distribution of anchovy in the NW Mediterranean

In order to estimate the abundance and the distribution of the anchovy in the Northwest Mediterranean, a standardised series of acoustic evaluation cruises was carried out in 1990, 1991, 1992, 1993 and 1995. The series showed that there was agreement between the biomass estimations and the registered landings in the area. On the other hand, some areas were identified where the recruits were largely localisedESTIMACIÓN ACÚSTICA DE LA ABUNDANCIA Y DISTRIBUCIÓN DE ANCHOA EN EL NOROESTE MEDITERRÁNEO. Una serie estandarizada de campañas de evaluación acústica ha sido realizada durante los años 1990, 1991, 1992, 1993 y 1995, para estimar la abundancia y distribución de la anchoa en el Noroeste del Mediterráneo. La serie mostró que hay consistencia entre las estimaciones de biomasa y los desembarcos registrados en el área. Por otro lado, se identificaron áreas en las que los reclutas son localizados mayoritariamentePublicado

Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by 1H NMR spectroscopy

Experimental models of traumatic brain injury (TBI) provide a useful tool for understanding the cerebral metabolic changes induced by this pathological condition. Here, we report on the time course of changes in cerebral metabolites after TBI and its correlation with early brain morphological changes using a combination of high-resolution proton magnetic resonance spectroscopy ( 1H MRS) and magnetic resonance imaging (MRI). Adult male Sprague-Dawley rats were subjected to closed head impact and examined by MRI at 1, 9, 24, 48, and and 72 h after the injury. Extracts from funnel frozen rat brains were then obtained and analyzed quantitatively by high-resolution 1H MRS. Finally, statistical multivariate analysis was carried out to identify the combination of cerebral metabolites that best described the time evolution of diffuse TBI. The temporal changes observed in the concentration of cerebral metabolites followed three different patterns. The first pattern included taurine, threonine, and glycine, with concentrations peaking 24 h after the injury. The second pattern included glutamate, GABA, and alanine, with concentrations remaining elevated between 24 and 48 h post-injury. The third one involved creatine-phosphocreatine, N-acetylaspartate, and myo-inositol, with concentrations peaking 48 h after the injury. A multivariate stepwise discriminant analysis revealed that the combination of the organic osmolytes taurine and myo-inositol allowed optimal discrimination among the different time groups. Our findings suggest that the profile of some specific brain molecules that play a role as organic osmolytes can be used to follow-up the progression of the early diffuse brain edema response induced by TBI. © Mary Ann Liebert, Inc.This work was partly supported by Spanish Ministry of Education and Science (grants SAF 2001-224 and SAF 2004-03197 to J.M.R. and S.C.) and by Spanish Ministry of Health (grants FISss C03/08, C03/10, and G03/155 to J.M.R. and S.C.).Peer Reviewe

The Photomorphogenic Signal: An Essential Component of Photoautotrophic Life

In this chapter, we focus on the role of the photomorphogenic signal to trigger the synthesis of photosynthetic genes and pigments during the greening process and later on, during photosynthetic plant development, with emphasis on the regulation of gene expression.Fil: Iñigo, Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Barber, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Sanchez Lamas, Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Iglesias, Francisco Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Cerdan, Pablo Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentin

Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review]

This article belongs to the Special Issue Yeasts Biochemistry and Biotechnology[Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of eukaryotic cells as soon as the techniques of molecular biology developed. Our molecular understandings of metabolism, cellular transport, DNA repair, gene expression and regulation, and the cell division cycle have all been obtained through biochemistry and genetic analysis using different yeasts. In this review, we summarize the role that yeasts have had in biological discoveries, the use of yeasts as biological tools, as well as past and on-going research projects on HMGB proteins along the way from yeast to cancer.This research was funded by Plan Estatal I+D+i, Instituto de Salud Carlos III (ISCIII, Spain) (grant nos. PI14/01031 and PI18/01417) and Ministerio de Ciencia e Innovación (grant no. PID2021-124564OB-I00), and cofunded by the Fondo Europeo de Desarrollo Regional-FEDER (The European Regional Development Fund-ERDF) “A way of Making Europe” and by Xunta de Galicia (Consolidación Grupos Referencia Competitiva grant no. ED431C 2020-08)Xunta de Galicia; ED431C 2020-0

Volatile composition of wines elaborated from organic and non-organic grapes

The aim of this work was to study the evolution of volatile compounds during the alcoholic fermentation of organic and non-organic grapes. To do this, grapes were cultivated using organic and non-organic grapes; their tasting showed some differences between both types of Monastrell grapes. Throughout the alcoholic fermentation, the samples of organic grapes had higher concentration of total alcohols but lower concentration of esters and acids than the samples of conventional ones. Therefore, the volatile composition of wines from two different cultivated grapes using both agronomic practices was different. Moreover, regarding to the volatile compounds that contributed directly to wine aroma, generally organic wine had more chemicals and floral aromas, while the wines from conventional practices had more fruity aromas. Principal component analysis (PCA) showed that it is possible to differentiate between both types of wines in terms of concentration of volatile compounds formed during the alcoholic fermentation. Consequently, agronomic practices affected the grape taste, the wine volatile composition and its quality.Peer Reviewe