5,685 research outputs found
First measurements of 15N fractionation in N2H+ toward high-mass star forming cores
We report on the first measurements of the isotopic ratio 14N/15N in N2H+
toward a statistically significant sample of high-mass star forming cores. The
sources belong to the three main evolutionary categories of the high-mass star
formation process: high-mass starless cores, high-mass protostellar objects,
and ultracompact HII regions. Simultaneous measurements of 14N/15N in CN have
been made. The 14N/15N ratios derived from N2H+ show a large spread (from ~180
up to ~1300), while those derived from CN are in between the value measured in
the terrestrial atmosphere (~270) and that of the proto-Solar nebula (~440) for
the large majority of the sources within the errors. However, this different
spread might be due to the fact that the sources detected in the N2H+
isotopologues are more than those detected in the CN ones. The 14N/15N ratio
does not change significantly with the source evolutionary stage, which
indicates that time seems to be irrelevant for the fractionation of nitrogen.
We also find a possible anticorrelation between the 14N/15N (as derived from
N2H+) and the H/D isotopic ratios. This suggests that 15N enrichment could not
be linked to the parameters that cause D enrichment, in agreement with the
prediction by recent chemical models. These models, however, are not able to
reproduce the observed large spread in 14N/15N, pointing out that some
important routes of nitrogen fractionation could be still missing in the
models.Comment: 2 Figures, accepted for publication in ApJ
The Foggy Disks Surrounding Herbig Ae Stars: a Theoretical Study of the H2O Line Spectra
Water is a key species in many astrophysical environments, but it is
particularly important in proto-planetary disks. So far,observations of water
in these objects have been scarce, but the situation should soon change thanks
to the Herschel satellite. We report here a theoretical study of the water line
spectrum of a proto-planetary disk surrounding Ae stars. We show that several
lines will be observable with the HIFI instrument onboard the Herschel Space
Observatory. We predict that some maser lines could also be observable with
ground telescopes and we discuss how the predictions depend not only on the
adopted physical and chemical model but also on the set of collisional
coefficients used and on the H2 ortho to para ratio through its effect on
collisional excitation. This makes the water lines observations a powerful, but
dangerous -if misused- diagnostic tool.Comment: Accepted for publication in ApJ Letter
New quantum chemical computations of formamide deuteration support a gas-phase formation of this prebiotic molecule
Based on recent work, formamide might be a potentially very important
molecule in the emergence of terrestrial life. Although detected in the
interstellar medium for decades, its formation route is still debated, whether
in the gas phase or on the dust grain surfaces. Molecular deuteration has
proven to be, in other cases, an efficient way to identify how a molecule is
synthesised. For formamide, new published observations towards the
IRAS16293-2422 B hot corino show that its three deuterated forms have all the
same deuteration ratio, 2--5%, and that this is a factor 3--8 smaller than that
measured for H2CO towards the IRAS16293-2422 protostar. Following a previous
work on the gas-phase formamide formation via the reaction NH2 + H2CO -> HCONH2
+ H, we present here new calculations of the rate coefficients for the
production of monodeuterated formamide through the same reaction, starting from
monodeuterated NH2 or H2CO. Some misconceptions regarding our previous
treatment of the reaction are also cleared up. The results of the new
computations show that, at the 100 K temperature of the hot corino, the rate of
deuteration of the three forms is the same, within 20%. On the contrary, the
reaction between non-deuterated species proceeds three times faster than that
with deuterated ones. These results confirm that a gas-phase route for the
formation of formamide is perfectly in agreement with the available
observations.Comment: MNRAS in pres
The L1157-B1 astrochemical laboratory: testing the origin of DCN
L1157-B1 is the brightest shocked region of the large-scale molecular
outflow, considered the prototype of chemically rich outflows, being the ideal
laboratory to study how shocks affect the molecular gas. Several deuterated
molecules have been previously detected with the IRAM 30m, most of them formed
on grain mantles and then released into the gas phase due to the shock. We aim
to observationally investigate the role of the different chemical processes at
work that lead to formation the of DCN and test the predictions of the chemical
models for its formation. We performed high-angular resolution observations
with NOEMA of the DCN(2-1) and H13CN(2-1) lines to compute the deuterated
fraction, Dfrac(HCN). We detected emission of DCN(2-1) and H13CN(2-1) arising
from L1157-B1 shock. Dfrac(HCN) is ~4x10 and given the uncertainties, we
did not find significant variations across the bow-shock. Contrary to HDCO,
whose emission delineates the region of impact between the jet and the ambient
material, DCN is more widespread and not limited to the impact region. This is
consistent with the idea that gas-phase chemistry is playing a major role in
the deuteration of HCN in the head of the bow-shock, where HDCO is undetected
as it is a product of grain-surface chemistry. The spectra of DCN and H13CN
match the spectral signature of the outflow cavity walls, suggesting that their
emission result from shocked gas. The analysis of the time dependent gas-grain
chemical model UCL-CHEM coupled with a C-type shock model shows that the
observed Dfrac(HCN) is reached during the post-shock phase, matching the
dynamical timescale of the shock. Our results indicate that the presence of DCN
in L1157-B1 is a combination of gas-phase chemistry that produces the
widespread DCN emission, dominating in the head of the bow-shock, and
sputtering from grain mantles toward the jet impact region.Comment: Accepted for publication in A&A. 7 pages, 5 Figures, 1 Tabl
The HIFI spectral survey of AFGL 2591 (CHESS). II. Summary of the survey
This paper presents the richness of submillimeter spectral features in the
high-mass star forming region AFGL 2591. As part of the CHESS (Chemical
Herschel Survey of Star Forming Regions) Key Programme, AFGL 2591 was observed
by the Herschel/HIFI instrument. The spectral survey covered a frequency range
from 480 up to 1240 GHz as well as single lines from 1267 to 1901 GHz (i.e. CO,
HCl, NH3, OH and [CII]). Rotational and population diagram methods were used to
calculate column densities, excitation temperatures and the emission extents of
the observed molecules associated with AFGL 2591. The analysis was supplemented
with several lines from ground-based JCMT spectra. From the HIFI spectral
survey analysis a total of 32 species were identified (including
isotopologues). In spite of the fact that lines are mostly quite week, 268
emission and 16 absorption lines were found (excluding blends). Molecular
column densities range from 6e11 to 1e19 cm-2 and excitation temperatures range
from 19 to 175 K. One can distinguish cold (e.g. HCN, H2S, NH3 with
temperatures below 70 K) and warm species (e.g. CH3OH, SO2) in the protostellar
envelope.Comment: Accepted to A&
Gas phase formation of the prebiotic molecule formamide: insights from new quantum computations
New insights into the formation of interstellar formamide, a species of great
relevance in prebiotic chemistry, are provided by electronic structure and
kinetic calculations for the reaction NH2 + H2CO -> NH2CHO + H. Contrarily to
what previously suggested, this reaction is essentially barrierless and can,
therefore, occur under the low temperature conditions of interstellar objects
thus providing a facile formation route of formamide. The rate coefficient
parameters for the reaction channel leading to NH2CHO + H have been calculated
to be A = 2.6x10^{-12} cm^3 s^{-1}, beta = -2.1 and gamma = 26.9 K in the range
of temperatures 10-300 K. Including these new kinetic data in a refined
astrochemical model, we show that the proposed mechanism can well reproduce the
abundances of formamide observed in two very different interstellar objects:
the cold envelope of the Sun-like protostar IRAS16293-2422 and the molecular
shock L1157-B2. Therefore, the major conclusion of this Letter is that there is
no need to invoke grain-surface chemistry to explain the presence of formamide
provided that its precursors, NH2 and H2CO, are available in the gas-phase.Comment: MNRAS Letters, in pres
SiO Emission in the Multi-Lobe Outflow associated with IRAS 16293-2422
We have mapped the thermal emission line of SiO (v = 0; J = 2-1) associated
with the quadrupolar molecular outflow driven by the very cold far-infrared
source IRAS 16293-2422. The SiO emission is significantly enhanced in the
northeastern red lobe and at the position ~50" east of the IRAS source. Strong
SiO emission observed at ~50" east of the IRAS source presents evidence for a
dynamical interaction between a part of the eastern blue lobe and the dense
ambient gas condensation, however, such an interaction is unlikely to be
responsible for producing the quadrupolar morphology. The SiO emission in the
northeastern red lobe shows the spatial and velocity structure similar to those
of the CO outflow, suggesting that the SiO emission comes from the molecular
outflow in the northeastern red lobe itself. The observed velocity structure is
reproduced by a simple spatio-kinematic model of bow shock with a shock
velocity of 19-24 km/s inclined by 30-45 deg from the plane of the sky. This
implies that the northeastern red lobe is independent of the eastern blue lobe
and that the quadrupolar structure is due to two separate bipolar outflows.
The SiO emission observed in the western red lobe has a broad pedestal shape
with low intensity. Unlike the SiO emission in the northeastern red lobe, the
spatial extent of the SiO emission in the western red lobe is restricted to its
central region. The spatial and velocity structures and the line profiles
suggest that three different types of the SiO emission are observed in this
outflow; the SiO emission arises from the interface between the outflowing gas
and the dense ambient gas clump, the SiO emission coming from the outflow lobe
itself, and the broad SiO emission with low intensity observed at the central
region of the outflow lobe.Comment: 14 pages, 6 figures (figures 1 and 4 are color), gzipped tar file, To
appear in the Ap
Clearance of human papillomavirus related anal condylomas after oral and endorectal multistrain probiotic supplementation in an HIV positive male: A case report.
Abstract
Go to:
Introduction:
Here we present the case of a 56-year-old human immunodeficiency virus (HIV)-infected man with multiple anal condylomas and positivity for human papilloma virus (HPV) 18 on anal brushing. Biopsies of the anal mucosa led to the diagnosis of Bowen's disease and a subsequent pelvic magnetic resonance imaging (MRI) scan evidenced multiple reactive lymphoadenopathies and large intra-anal condylomas. The patient was treated with a complete excision of Bowen's lesion and with a 4 months course of supplementation with a high concentration multistrain probiotic formulation administered orally and by rectal instillation with the purpose to reduce local inflammation and to enhance local mucosal immunity.
Go to:
Conclusion:
An MRI performed at the end of the supplementation period evidenced the clearance of the anal condylomas previously described and no evidence of residual lymphadenopathies. Trials are therefore required to confirm this therapeutic possibility and for a better understanding of the mechanisms by which this specific probiotic formulation interacts with local epithelium when administered by the anal route
Heavy water around the L1448-mm protostar
Context: L1448-mm is the prototype of a low-mass Class 0 protostar driving a
high-velocity jet. Given its bright H2O spectra observed with ISO, L1448-mm is
an ideal laboratory to observe heavy water (HDO) emission. Aims: Our aim is to
image the HDO emission in the protostar surroundings, the possible occurrence
of HDO emission also investigating off L1448-mm, towards the molecular outflow.
Methods: We carried out observations of L1448-mm in the HDO(1_10-1_11) line at
80.6 GHz, an excellent tracer of HDO column density, with the IRAM Plateau de
Bure Interferometer. Results: We image for the first time HDO emission around
L1448-mm. The HDO structure reveals a main clump at velocities close to the
ambient one towards the the continuum peak that is caused by the dust heated by
the protostar. In addition, the HDO map shows tentative weaker emission at
about 2000 AU from the protostar towards the south, which is possibly
associated with the walls of the outflow cavity opened by the protostellar
wind. Conclusions: Using an LVG code, modelling the density and temperature
profile of the hot-corino, and adopting a gas temperature of 100 K and a
density of 1.5 10^8 cm^-3, we derive a beam diluted HDO column density of about
7 10^13 cm^-2, corresponding to a HDO abundance of about 4 10^-7. In addition,
the present map supports the scenario where HDO can be efficiently produced in
shocked regions and not uniquely in hot corinos heated by the newly born star.Comment: Accepted by A&A as Letter; 5 pages, 3 figure
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Shocks and PDRs in an intermediate mass star forming globule: the case of IC1396N
The dark globule IC1396N is a typical example of a star formation process induced by radiation driven implosion due to the strong UV field from a nearby O6 star. The IRAS source embedded in the globule and its associated molecular outflow have been observed with the Long Wavelength Spectrometer (LWS) on ISO revealing an extremely rich spectrum including: CO rotational lines from J=14-13 up to J=28-27, rotational lines from ortho-H2O, OH lines involving the first four rotational levels of both ladders, atomic (OI 63μm, OI 145μm) and ionic (CII 157μm, OIII 52μm, OIII 88μm) lines. A complex picture arises, where an externally illuminated PDR coexists with strong C-shocks within IC1396N and whose origin is not clear
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