506 research outputs found

    Selective formation and cleavage of carbon–heteroatom bonds using visible-light photocatalysis

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    Head frames to image guidance, a brief history of stereotactic radiosurgery

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    "Hello Emily, how are you today?" Personalised dialogue in a toy to engage children

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    In line with the growing interest in conversational agents as companions, we are developing a toy companion for children that is capable of engaging interactions and of developing a long-term relationship with them, and is extensible so as to evolve with them. In this paper, we investigate the importance of personalising interaction both for engagement and for long-term relationship development. In particular, we propose a framework for representing, gathering and using personal knowledge about the child during dialogue interaction

    Body composition in Karate: a dual-energy X-ray absorptiometry study

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    Karate is a widely practiced combat sport. Karatekas' body composition has typically been obtained in small groups using skinfolds or bioelectric impedance. In this work, we assessed three-compartment body composition using the accurate dual-energy X-ray absorptiometry technique (QDR Horizon, Hologic) in a large sample (n = 58; 74% males) of black belt karatekas. Stature-adjusted body composition indices (fat mass index; fat-free mass index; bone mineral apparent density) were calculated. The Student's t-test was used for group-group analysis. Correlation was assessed using the Pearson's r. The ability of fat-free soft tissue mass to predict bone mineral content and areal bone mineral density was assessed with linear regression. Reference mean and quartile values for whole-body and regional body composition were obtained for the male athletes. The body composition indices were generally more favorable in the male than female karatekas. The bone mineral apparent density was similar in the males and females at all sites except the right leg. The fat-free soft tissue mass predicted the bone mineral content and areal bone mineral density with good accuracy (R-2 = 0.542-0.827; p < 0.001 for all models). The data presented in this paper are expected to be of use for karate coaches, physical trainers, and participants interested in assessing and monitoring athletes' body composition

    A novel two-stage kinetic model for surface DBD simulations in air

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    In this work, a novel 0D model for the evaluation of O-3 and NO2 produced by a surface dielectric barrier discharge (SDBD) in a closed environment is presented. The model is composed by two coupled sub-models, a discharge sub-model and an afterglow one. The first one, simulating the discharge regime and consequently including electron impact reactions, aims to calculate the production rates of a set of key species (atomic oxygen, excited states of molecular oxygen and molecular nitrogen). These latter are the input of the afterglow sub-model, that simulates the afterglow regime. We introduce a methodology to relate the production rates of the above mentioned species to the input power of the SDBD reactor. The simulation results are validated by a comparison with experimental data from absorption spectroscopy. The experimental measurements are carried out as follows. First, the discharge is turned on until the NO2 number density reaches steady state. Then, the discharge is turned off for several minutes. Finally, the discharge is turned on again to observe the effects of the NO2 concentration on ozone dynamics. The entire process is done without opening the box. The system operating in all the above-listed conditions is simulated for three different levels of input power

    Experimental conditions to suppress edge localised modes by magnetic perturbations in the ASDEX Upgrade tokamak

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    Access conditions for full suppression of Edge Localised Modes (ELMs) by Magnetic Perturbations (MP) in low density high confinement mode (H-mode) plasmas are studied in the ASDEX Upgrade tokamak. The main empirical requirements for full ELM suppression in our experiments are: 1. The poloidal spectrum of the MP must be aligned for best plasma response from weakly stable kink-modes, which amplify the perturbation, 2. The plasma edge density must be below a critical value, 3.3×10193.3 \times 10^{19}~m−3^{-3}. The edge collisionality is in the range νi∗=0.15−0.42\nu^*_i = 0.15-0.42 (ions) and νe∗=0.15−0.25\nu^*_e = 0.15-0.25 (electrons). However, our data does not show that the edge collisionality is the critical parameter that governs access to ELM suppression. 3. The pedestal pressure must be kept sufficiently low to avoid destabilisation of small ELMs. This requirement implies a systematic reduction of pedestal pressure of typically 30\% compared to unmitigated ELMy H-mode in otherwise similar plasmas. 4. The edge safety factor q95q_{95} lies within a certain window. Within the range probed so far, q95=3.5−4.2q_{95}=3.5-4.2, one such window, q95=3.57−3.95q_{95}=3.57-3.95 has been identified. Within the range of plasma rotation encountered so far, no apparent threshold of plasma rotation for ELM suppression is found. This includes cases with large cross field electron flow in the entire pedestal region, for which two-fluid MHD models predict that the resistive plasma response to the applied MP is shielded

    Epidemiology of simultaneous medullary and papillary thyroid carcinomas (MTC/PTC): An Italian multicenter study

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    Background: The concomitant presence of papillary thyroid cancer (PTC) and medullary TC (MTC) is rare. In this multicentric study, we documented the epidemiological characteristics, disease conditions and clinical outcome of patients with simultaneous MTC/PTC. Methods: We collected data of patients with concomitant MTC/PTC at 14 Italian referral centers. Results: In total, 183 patients were enrolled. Diagnosis was mostly based on cytological examination (n = 58, 32%). At diagnosis, in the majority of cases, both PTC (n = 142, 78%) and MTC (n = 100, 54%) were at stage I. However, more cases of stage II\u2013IV were reported with MTC (stage IV: n = 27, 15%) compared with PTC (n = 9, 5%). Information on survival was available for 165 patients: 109 patients (66%) were disease-free for both PTC and MTC at the last follow-up. Six patients died from MTC. Median time to progression was 123 months (95% confidence interval (CI): 89.3\u2013156.7 months). Overall, 45% of patients were disease-free after >10 years from diagnosis (125 months); this figure was 72.5% for PTC and 51.1% for MTC. Conclusions: When MTC and PTC are concurrent, the priority should be given to the management of MTC since this entity appears associated with the most severe impact on prognosis
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