386 research outputs found

    Letter from Catherine Hicks & John Hicks to James B. Finley

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    Catherine and John Hicks have heard that Finley might be coming to Kansas to see his Indian friends, and they are delighted to hear it. Many years have passed since we first met in the wilderness of Sandusky and learned to sing praises to the Redeemer. It would mean a great deal to see Finley before they die. Abstract Number - 855https://digitalcommons.owu.edu/finley-letters/1342/thumbnail.jp

    The Integration of Social Studies Units and Language to Enrich the Kindergarten Curriculum

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    The goals of this project have been to review the relevant literature and provide activities for integrating subject areas of social studies and language in the kindergarten classroom. Research has indicated that the primary school child has learned best when the curriculum is relevant to the child\u27s everyday life.Included in the curriculum are the communication skills denoted by the Duval County\u27s Instructional Management System. These skills are integrated with the social studies units from the Kindergarten Keys curriculum. The topics for each unit have been those topics that children have had frequent exposure to in their everyday life.Conclusions about the study were arrived at through a review of the literature and development of the curriculum. Included were recommendations for improvement and expansion

    Field guide for didymo DNA sample collection

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    This protocol is designed for work in two-person teams for both safety and to maximise sample integrity

    Developing public servants for the future

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    The majority of UK civil servants are ‘developed’ within a particular service or profession and there is frequently very little movement into other service areas. Many current leaders therefore have limited experiences in services and organizations other than their own. This paper presents a new graduate programme for the training and development of future public leaders in Wales. The programme is a leadership and development programme for civil and public servants, exposing them to a range of services. The intention is that, through these experiences, future leaders will approach problems from a multi-service perspective, will be better networked and ready to deal with complexity. Areas of good practice are highlighted, together with some of the challenges of developing leaders in this way

    Gender-specific epidemiology of diabetes: a representative cross-sectional study

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    <p>Abstract</p> <p>Background</p> <p>Diabetes and its associated complications are part of a chronic disease global epidemic that presents a public health challenge. Epidemiologists examining health differences between men and women are being challenged to recognise the biological and social constructions behind the terms 'sex' and/or 'gender', together with social epidemiology principles and the life course approach. This paper examines the epidemiology of a population with diabetes from the north-west metropolitan region of South Australia.</p> <p>Methods</p> <p>Data were used from a sub-population with diabetes (n = 263), from 4060 adults aged 18 years and over living in the north-west suburbs of Adelaide, South Australia. Eligible respondents were asked to participate in a telephone interview, a self-report questionnaire and a biomedical examination. Diabetes (undiagnosed and diagnosed) was determined using self-reported information and a fasting blood test administered to participants. Data were analysed using SPSS (Version 10.0) and EpiInfo (Version 6.0).</p> <p>Results</p> <p>Factors associated with diabetes for both men and women were being aged 40 years and over, and having a low gross annual household income, obesity and a family history of diabetes. In addition, being an ex-smoker and having low cholesterol levels were associated with diabetes among men. Among women, having a high waist-hip ratio, high blood pressure and reporting a previous cardiovascular event or mental health problem were associated with diabetes.</p> <p>Conclusion</p> <p>The results found that men and women with diabetes face different challenges in the management of their condition. Public health implications include a need for quality surveillance data, including epidemiological life course, social, behavioural, genetic and environmental factors. This will enrich the evidence base for health promotion professionals and allow policy makers to draw inferences and conclusions for interventions and planning purposes.</p

    Local seismicity around the Chain Transform Fault at the Mid-Atlantic Ridge from OBS observations

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    Summary Seismicity along transform faults provides important constraints for our understanding of the factors that control earthquake ruptures. Oceanic transform faults are particularly informative due to their relatively simple structure in comparison to their continental counterparts. The seismicity of several fast-moving transform faults has been investigated by local networks, but as of today there been few studies of transform faults in slow spreading ridges. Here we present the first local seismicity catalogue based on event data recorded by a temporary broadband network of 39 ocean bottom seismometers located around the slow-moving Chain Transform Fault (CTF) along the Mid-Atlantic Ridge (MAR) from March 2016 to March 2017. We locate 972 events in the area by simultaneously inverting for a 1-D velocity model informed by the event P- and S-arrival times. We refine the depths and focal mechanisms of the larger events using deviatoric moment tensor inversion. Most of the earthquakes are located along the CTF (700) and Romanche transform fault (94) and the MAR (155); a smaller number (23) can be observed on the continuing fracture zones or in intraplate locations. The ridge events are characterised by normal faulting and most of the transform events are characterised by strike slip faulting, but with several reverse mechanisms that are likely related to transpressional stresses in the region. CTF events range in magnitude from 1.1 to 5.6 with a magnitude of completeness around 2.3. Along the CTF we calculate a b-value of 0.81 ± 0.09. The event depths are mostly shallower than 15 km below sea level (523), but a small number of high-quality earthquakes (16) are located deeper, with some (8) located deeper than the brittle-ductile transition as predicted by the 600˚C-isotherm from a simple thermal model. The deeper events could be explained by the control of seawater infiltration on the brittle failure limit

    The Synergistic Action of Melittin and Phospholipase A2 with Lipid Membranes: Development of Linear Dichroism for Membrane-Insertion Kinetics

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    Here we present data on the kinetics of insertion of melittin, a peptide from bee venom, into lipid membranes of different composition. Another component of bee venom is the enzyme phospholipase A2 (PLA₂). We have examined the interaction of melittin and PLA₂ with liposomes both separately and combined and demonstrate that they work synergistically to disrupt the membranes. A dramatic difference in the action of melittin and PLA₂ is observed when the composition of the membrane is altered. Temperature also has a large effect on the kinetics of insertion and membrane disruption. We use a combination of techniques to measure liposome size (dynamic light scattering), peptide secondary structure (circular dichroism spectroscopy), peptide orientation relative to the membrane (linear dichroism spectroscopy) and enzymatic digestion of the lipids (mass spectrometry)

    Acceleration predicts energy expenditure in a fat, flightless, diving bird

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    Funding The project was supported logistically by the French Polar Institute and funded by the PEW fellowship to Y.R.-C., the WWF-UK, and the Zone Atelier Antarctique et Terres Australes from the CNRS. D.M.W. received funding from the European Union's Horizon 2020 research and innovation programme under the Marie SkƂodowska‐Curie Individual Fellowship Grant Agreement No. 748026.Peer reviewedPublisher PD

    Implementation of blinded outcome assessment in the Effective Verruca Treatments trial (EverT) – lessons learned

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    Trials using inadequate levels of blinding may report larger effect sizes than blinded studies. It has been suggested that blinded outcome assessment in open trials may in some cases be undertaken by assessments of photographs. The aim of this paper is to explore the effect of using different methods to assess the primary outcome in the EVerT (Effective Verruca Treatments) trial. It also aims to give an overview of the experiences of using digital photographs within the trial. Methods We undertook a secondary analysis to explore the effect of using three different methods to assess the primary outcome in the EVerT trial: assessment of digital photographs by blinded healthcare professionals; blinded healthcare professional assessment at the recruiting site and patient self-report. The verruca clearance rates were calculated using the three different methods of assessment. A Cohen’s kappa measure of inter-rater agreement was used to assess the agreement between the methods. We also investigated the experiences of healthcare professionals using digital photographs within the trial. Results Digital photographs for 189 out of 240 (79 %) patients in the trial were received for outcome assessment. Of the 189 photographs, 30 (16 %) were uninterpretable. The overall verruca clearance rates were 21 % (43/202,) using the unblinded patient self-reported outcome, 6 % (9/159,) using blinded assessment of digital photographs and 14 % (30/210,) using blinded outcome assessment at the site. Conclusions Despite differences in the clearance rates found using different methods of outcome assessment, this did not change the original conclusion of the trial, that there is no evidence of a difference in effectiveness between cryotherapy and salicylic acid. Future trials using digital photographs should consider individual training needs at sites and have a backup method of assessment agreed a priori
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