A estimulação colinérgica pode mitigar o risco arrítmico durante o tratamento de COVID- 19

ISSN: 2574-9838 DOI: 10.15406/ipmrj.2020.05.00248The COVID-19 pandemic led scientists all over the world to try finding potential pharmacologic options to treat infected patients. In this context, old antimalarial drugs as chloroquine and hydroxychloroquine has emerged as promising treatments. While scientists claimed that there was not enough scientific evidence supporting the use of these medicines in patients infected by the SARS-Cov-2, politicians and lay people argument that even without solid evidences for the benefits, there would be nothing to lose if these drugs were prescribed.SimNão tem no Editoria

Feeding and foraging ecology of Trindade petrels Pterodroma arminjoniana during the breeding period in the South Atlantic Ocean

Seabirds breeding in tropical environments experience high energetic demands, when foraging in an oligotrophic environment. The globally threatened Trindade petrel Pterodroma arminjoniana has its largest colony in Trindade Island (20°30′S–29°19′W) inside the oligotrophic South Atlantic Subtropical Gyre. Diet sampling methods, geolocator tracking and stable isotope analysis were used to describe its diet, compare foraging trips and distributions, and assess temporal variations in the trophic niche throughout the breeding period. Diet consisted mainly of squid and fish. The high species diversity and wide range of prey sizes consumed suggests the use of multiple foraging techniques. Stable isotope mixing models confirm that Trindade petrels rely mainly on squid throughout the breeding period. Its broad isotopic niche seems to reflect both a diverse diet and foraging range, since birds can reach up to 3335 km from the colony. Isotopic niche showed limited variation even in an 8-year interval, apparently due to oceanographic stability, although changes in the isotopic niche have demonstrated an adjustment to different conditions in different seasons. Petrels change foraging areas and prey during the breeding period: pre-incubating birds use more productive areas west of Trindade Island and obtain low trophic position prey; incubating petrels perform longer trips southward to consume prey of high trophic position; and chick-rearing petrels use areas around the island. These results demonstrate that to deal with high demand breeding in a colony surrounded by oligotrophic waters, Trindade petrels need to explore wide foraging areas and utilize a diverse diet, besides adjusting trophic niche according to breeding stage

Measurement of the Inclusive Jet Cross Section in pp Collisions at root s=7 TeV

The inclusive jet cross section is measured in pp collisions with a center-of-mass energy of 7 TeV at the Large Hadron Collider using the CMS experiment. The data sample corresponds to an integrated luminosity of 34 pb(-1). The measurement is made for jet transverse momenta in the range 18-1100 GeV and for absolute values of rapidity less than 3. The measured cross section extends to the highest values of jet p(T) ever observed and, within the experimental and theoretical uncertainties, is generally in agreement with next-to-leading-order perturbative QCD predictions. RI Hektor, Andi/G-1804-2011; Wulz, Claudia-Elisabeth/H-5657-2011; Chen, Jie/H-6210-2011; Bolton, Tim/A-7951-2012; Krammer, Manfred/A-6508-2010; Tinoco Mendes, Andre David/D-4314-2011; Petrushanko, Sergey/D-6880-2012; Lokhtin, Igor/D-7004-2012; Kodolova, Olga/D-7158-2012; Dudko, Lev/D-7127-2012; Perfilov, Maxim/E-1064-2012; Belyaev, Andrey/E-1540-2012; Katkov, Igor/E-2627-2012; Boos, Eduard/D-9748-2012; Snigirev, Alexander/D-8912-2012; Tomei, Thiago/E-7091-2012; Focardi, Ettore/E-7376-2012; Raidal, Martti/F-4436-2012; Novaes, Sergio/D-3532-2012; Padula, Sandra /G-3560-2012; Flix, Josep/G-5414-2012; Fruhwirth, Rudolf/H-2529-2012; Torassa, Ezio/I-1788-201

Measurement of the underlying event activity at the LHC with root s=7 TeV and comparison with root s=0.9 TeV

A measurement of the underlying activity in events with a jet of transverse momentum in the several GeV region is performed in proton-proton collisions at root s = 0.9 and 7 TeV, using data collected by the CMS experiment at the LHC. The production of charged particles with pseudorapidity vertical bar eta vertical bar 0.5 GeV = c is studied in the azimuthal region transverse to that of the leading set of charged particles forming a track-jet. A significant growth of the average multiplicity and scalar-p(T) sum of the particles in the transverse region is observed with increasing p(T) of the leading track-jet, followed by a much slower rise above a few GeV/c. For track-jet p(T) larger than a few GeV/c, the activity in the transverse region is approximately doubled with a centre-of-mass energy increase from 0.9 to 7 TeV. Predictions of several QCD-inspired models as implemented in PYTHIA are compared to the data. RI Wulz, Claudia-Elisabeth/H-5657-2011; Chen, Jie/H-6210-2011; Bolton, Tim/A-7951-2012; Stahl, Achim/E-8846-2011; Yang, Fan/B-2755-2012; buotempo, salvatore/B-5210-2012; Krammer, Manfred/A-6508-2010; Tinoco Mendes, Andre David/D-4314-2011; Petrushanko, Sergey/D-6880-2012; Lokhtin, Igor/D-7004-2012; Kodolova, Olga/D-7158-2012; Dudko, Lev/D-7127-2012; Perfilov, Maxim/E-1064-2012; Belyaev, Andrey/E-1540-2012; Katkov, Igor/E-2627-2012; Boos, Eduard/D-9748-2012; Snigirev, Alexander/D-8912-2012; Tomei, Thiago/E-7091-2012; Focardi, Ettore/E-7376-2012; Raidal, Martti/F-4436-2012; Novaes, Sergio/D-3532-2012; Padula, Sandra /G-3560-2012; Lujan Center, LANL/G-4896-2012; Flix, Josep/G-5414-2012; Fruhwirth, Rudolf/H-2529-2012; Azzi, Patrizia/H-5404-2012; Torassa, Ezio/I-1788-201

Performance of the CMS missing transverse momentum reconstruction in pp data at √s= 8 TeV

The performance of missing transverse energy reconstruction algorithms is presented using root s = 8 TeV proton-proton (pp) data collected with the CMS detector. Events with anomalous missing transverse energy are studied, and the performance of algorithms used to identify and remove these events is presented. The scale and resolution for missing transverse energy, including the effects of multiple pp interactions (pileup), are measured using events with an identified Z boson or isolated photon, and are found to be well described by the simulation. Novel missing transverse energy reconstruction algorithms developed specifically to mitigate the effects of large numbers of pileup interactions on the missing transverse energy resolution are presented. These algorithms significantly reduce the dependence of the missing transverse energy resolution on pileup interactions. Finally, an algorithm that provides an estimate of the significance of the missing transverse energy is presented, which is used to estimate the compatibility of the reconstructed missing transverse energy with a zero nominal value

Searches for supersymmetry based on events with b jets and four W bosons in pp collisions at 8 TeV

Five mutually exclusive searches for supersymmetry are presented based on events in which b jets and four W bosons are produced in proton-proton collisions at root s = 8TeV. The data, corresponding to an integrated luminosity of 19.5 fb(-1), were collected with the CMS experiment at the CERN LHC in 2012. The five studies differ in the leptonic signature from the W boson decays, and correspond to all-hadronic, single-lepton, opposite-sign dilepton, same-sign dilepton, and >= 3 lepton final states. The results of the five studies are combined to yield 95% confidence level limits for the gluino and bottom-squark masses in the context of gluino and bottom-squark pair production, respectively. In the limit when the lightest supersymmetric particle is light, gluino and bottom squark masses are excluded below 1280 and 570 GeV, respectively

Measurement of the production cross section for a W boson and two b jets in pp collisions at root s=7 TeV

The production cross section for a Wboson and two b jets is measured using proton-proton collisions at v root s = 7 TeV in a data sample collected with the CMS experiment at the LHC corresponding to an integrated luminosity of 5.0 fb(-1). The W + bbevents are selected in the W..decay mode by requiring a muon with transverse momentum pT> 25GeVand pseudorapidity |eta| 25GeVand |eta| < 2.4. The measured W + bbproduction cross section in the fiducial region, calculated at the level of final-state particles, is s(pp. W + bb) xB(W..) = 0.53 +/- 0.05 (stat.) +/- 0.09 (syst.) +/- 0.06 (theo.) 0.01 (lum.) pb, in agreement with the standard model prediction. In addition, kinematic distributions of the W + bbsystem are in agreement with the predictions of a simulation usingMadGraphandpythia

Search for a standard model-like Higgs boson in the mu(+)mu(-) and e(+)e(-) decay channels at the LHC

A search is presented for a standard model-like Higgs boson decaying to the mu(+)mu(-) or e(+)e(-) final states based on proton-proton collisions recorded by the CMS experiment at the CERN LHC. The data correspond to integrated luminosities of 5.0 fb(-1) at a centre-of-mass energy of 7 TeV and 19.7 fb(-1) at 8 TeV for the mu(+)mu(-) search, and of 19.7 fb(-1) at 8 TeV for the e(+)e(-) search. Upper limits on the production cross section times branching fraction at the 95% confidence level are reported for Higgs boson masses in the range from 120 to 150 GeV. For a Higgs boson with a mass of 125 GeV decaying to mu(+)mu(-), the observed (expected) upper limit on the production rate is found to be 7.4 (6.5(-1.9)(+2.8)) times the standard model value. This corresponds to an upper limit on the branching fraction of 0.0016. Similarly, for e(+)e(-), an upper limit of 0.0019 is placed on the branching fraction, which is approximate to 3.7 x 10(5) times the standard model value. These results, together with recent evidence of the 125 GeV boson coupling to tau-leptons with a larger branching fraction consistent with the standard model, confirm that the leptonic couplings of the new boson are not flavour-universal