Conservative formulations of general relativistic kinetic theory

Experience with core-collapse supernova simulations shows that accurate accounting of total particle number and 4-momentum can be a challenge for computational radiative transfer. This accurate accounting would be facilitated by the use of particle number and 4-momentum transport equations that allow transparent conversion between volume and surface integrals in both configuration and momentum space. Such conservative formulations of general relativistic kinetic theory in multiple spatial dimensions are presented in this paper, and their relevance to core-collapse supernova simulations is described.Comment: 48 page

Stellar Wind Accretion in GX301-2: Evidence for a High-density Stream

The X-ray binary system GX301-2 consists of a neutron star in an eccentric orbit accreting from the massive early-type star WRAY 977. It has previously been shown that the X-ray orbital light curve is consistent with existence of a gas stream flowing out from Wray 977 in addition to its strong stellar wind. Here, X-ray monitoring observations by the Rossi X-ray Timing Explorer (RXTE)/ All-Sky-Monitor (ASM) and pointed observations by the RXTE/ Proportional Counter Array (PCA) over the past decade are analyzed. We analyze both the flux and column density dependence on orbital phase. The wind and stream dynamics are calculated for various system inclinations, companion rotation rates and wind velocities, as well as parametrized by the stream width and density. These calculations are used as inputs to determine both the expected accretion luminosity and the column density along the line-of-sight to the neutron star. The model luminosity and column density are compared to observed flux and column density vs. orbital phase, to constrain the properties of the stellar wind and the gas stream. We find that the change between bright and medium intensity levels is primarily due to decreased mass loss in the stellar wind, but the change between medium and dim intensity levels is primarily due to decreased stream density. The mass-loss rate in the stream exceeds that in the stellar wind by a factor of 2.5. The quality of the model fits is significantly better for lower inclinations, favoring a mass for WRAY 977 of 53 to 62 Msun.Comment: 19 pages, 6 figure

Connective tissue activation. xxxv. detection of connective tissue activating peptide–iii isoforms in synovium from osteoarthritis and rheumatoid arthritis patients: patterns of interaction with other synovial cytokines in cell culture

Objective. To determine whether extracts of unincubated osteoarthritis (OA) and rheumatoid arthritis (RA) synovial tissue contain connective tissue activating peptide–III (CTAP-III) isoforms and prostaglandin E 2 (PGE 2 ), and whether such extracts have growth-promoting activity, and to determine whether binary combinations of CTAP-III with other cytokines reported to be present in synovial tissue lead to synergistic, additive, or inhibitory effects on growth. Methods. Acid–ethanol extracts of human synovium were examined for growth-promoting activity by measuring formation of 14 C-glycosaminoglycan ( 14 CGAG) and 3 H-DNA in synovial cell cultures; PGE 2 was measured by enzyme immunoassay, and CTAP-III isoforms were identified by Western blotting of extracted proteins separated by sodium dodecyl sulfate–polyacrylamide gel electrophoresis. Growth-promoting activity of CTAP-III and other cytokines was tested in synovial cultures treated with the agonists singly and in binary combination, by measuring changes in synthesis of 14 C-GAG and 3 H-DNA. Results. Platelet-derived CTAP-III and a cleavage isoform with the electrophoretic mobility of CTAP-III–des 1–15/neutrophil-activating peptide–2 (NAP-2) and PGE 2 were found in biologically active extracts of synovial samples from patients with RA and OA. Five growth factors (recombinant epidermal growth factor [rEGF], recombinant interleukin-1Β [rIL-1Β], basic fibroblast growth factor [bFGF], PGE 1 , and PGE 2 ) in binary combination with CTAP-III showed synergism in stimulating GAG synthesis; two (recombinant platelet-derived growth factor type BB [rPDGF-BB] and recombinant transforming growth factor Β [rTGFΒ]) had an additive effect. In combination with CTAP-III, rEGF and rPDGF-BB had a synergistic effect in promoting DNA synthesis, rTGFΒ and rbFGF had an additive effect, and rIL-1Β, PGE 1 , and PGE 2 were antagonistic. Conclusions. The results suggest that, in addition to endogenous factors, CTAP-III and other plateletderived cytokines may play roles in regulating synovial cell metabolism in RA and OA, and that combinations of growth factors may be more significant than single agents in amplification or suppression of important cell functions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37793/1/1780350712_ftp.pd

Cáncer de la vesícula biliar: limitaciones diagnósticas y terapéuticas

Antecedentes: El cáncer de la vesícula biliar tienebaja frecuencia en Sudamérica, excepto en Chile;por lo general es diagnosticado y tratado en etapasavanzadas.Objetivo: Estudiar la frecuencia, el perfil demográfico,el cuadro clínico, el diagnóstico y los resultadosde la cirugía en pacientes con cáncer vesicularMaterial y método: estudio descriptivo y retrospectivobasado en pacientes sometidos a colecistectomíapor litiasis en el periodo 1992-2002. Fueronseleccionados los casos comprobados de cáncervesicular; se evalúan: frecuencia, perfil demográfico,cuadro clínico, aportes de los medios de diagnósticoy resultados inmediatos del tratamiento.Resultados: Fueron hallados 16 casos de cáncervesicular sobre 3239 colecistectomías (0.5%); 15fueron mujeres. La edad media fue 63 años (r 53-77).El dolor fue el principal motivo de consulta. El 75%presentó ictericia + coluria + acolia. La ecografíacomprobó engrosamiento de la pared vesicular en 6casos y vesícula escleroatrófica en uno.La colecistectomía simple fue efectuada en 2 casos;ella se asoció a drenaje biliar externo en 3, biopsiahepática en 2 y a derivación biliodigestiva en 1.Una derivación biliodigestiva, dos drenajes biliaresexternos, 4 biopsias y una prótesis endoscópica completanla serie.Uno de los pacientes presentó una fístula biliodigestiva.Cinco pacientes fallecieron (31%): 4 porcomplicaciones infecciosas con falla orgánica múltipley 1 por tromboembolismo pulmonar.Conclusión: El cáncer vesicular es raro, predominaen el sexo femenino y se acompaña con frecuenciade obstrucción biliar. La orientación diagnóstica escasi nula por ecografía; sólo en engrosamiento localizadocoexistente con la litiasis vesicular parecesignificativo y obliga a realizar una biopsia extemporánea

Testing Hydrodynamic Models of LMC X-4 with UV and X-ray Spectra

We compare the predictions of hydrodynamic models of the LMC X-4 X-ray binary system with observations of UV P Cygni lines with the GHRS and STIS spectrographs on the Hubble Space Telescope. The hydrodynamic model determines density and velocity fields of the stellar wind, wind-compressed disk, accretion stream, Keplerian accretion disk, and accretion disk wind. We use a Monte Carlo code to determine the UV P Cygni line profiles by simulating the radiative transfer of UV photons that originate on the star and are scattered in the wind. The qualitative orbital variation predicted is similar to that observed, although the model fails to reproduce the strong orbital asymmetry (the observed absorption is strongest for phi>0.5). The model predicts a mid-eclipse X-ray spectrum, due almost entirely to Compton scattering, with a factor 4 less flux than observed with ASCA. We discuss how the model may need to be altered to explain the spectral variability of the system.Comment: 11 figures, accepted by Ap

Aspherical Explosion Models for SN 1998bw/GRB 980425

The recent discovery of the unusual supernova SN1998bw and its apparent correlation with the gamma-ray burst GRB 980425 has raised new issues concerning both the GRB and supernovae. Although the spectra resemble those of TypeIc supernovae, there are distinct differences at early times and SN1998bw appeared to be unusually bright and red at maximum light. The apparent expansion velocities inferred by the Doppler shift of (unidentified) absorption features appeared to be high, making SN1998bw a possible candidate for a "hypernova" with explosion energies between 20 and 50E51 erg and ejecta masses in excess of 6 - 15 M_o. Based on light curve calculations for aspherical explosions and guided by the polarization observations of "normal" SNIc and related events, we present an alternative picture that allows SN1998bw to have an explosion energy and ejecta mass consistent with core collapse supernovae (although at the 'bright' end). We show that the LC of SN1998bw can be understood as result of an aspherical explosion along the rotational axis of a basically spherical, non-degenerate C/O core of massive star with an explosion energy of 2foe and a total ejecta mass of 2 M_o if it is seen from high inclinations with respect to the plane of symmetry. In this model, the high expansion velocities are a direct consequence of an aspherical explosion which, in turn, produces oblate iso-density contours. It suggests that the fundamental core-collapse explosion process itself is strongly asymmetric.Comment: 12 pages, 8 figures, latex, aas2pp4.sty, submitted to Ap

The Evolution of Relativistic Binary Progenitor Systems

Relativistic binary pulsars, such as B1534+12 and B1913+16 are characterized by having close orbits with a binary separation of ~ 3 R_\sun. The progenitor of such a system is a neutron star, helium star binary. The helium star, with a strong stellar wind, is able to spin up its compact companion via accretion. The neutron star's magnetic field is then lowered to observed values of about 10^{10} Gauss. As the pulsar lifetime is inversely proportional to its magnetic field, the possibility of observing such a system is, thus, enhanced by this type of evolution. We will show that a nascent (Crab-like) pulsar in such a system can, through accretion-braking torques (i.e. the "propeller effect") and wind-induced spin-up rates, reach equilibrium periods that are close to observed values. Such processes occur within the relatively short helium star lifetimes. Additionally, we find that the final outcome of such evolutionary scenarios depends strongly on initial parameters, particularly the initial binary separation and helium star mass. It is, indeed, determined that the majority of such systems end up in the pulsar "graveyard", and only a small fraction are strongly recycled. This fact might help to reconcile theoretically expected birth rates with limited observations of relativistic binary pulsars.Comment: 24 pages, 10 Postscript figures, Submitted to The Astrophysical Journa

Neon Abundances from a Spitzer/IRS Survey of Wolf-Rayet Stars

We report on neon abundances derived from {\it Spitzer} high resolution spectral data of eight Wolf-Rayet (WR) stars using the forbidden line of [\ion{Ne}{3}] 15.56 microns. Our targets include four WN stars of subtypes 4--7, and four WC stars of subtypes 4--7. We derive ion fraction abundances $\gamma$ of Ne^{2+} for the winds of each star. The ion fraction abundance is a product of the ionization fraction $Q_{\rm i}$ in stage i and the abundance by number ${\cal A}_E$ of element E relative to all nuclei. Values generally consistent with solar are obtained for the WN stars, and values in excess of solar are obtained for the WC stars.Comment: to appear in Astrophysical Journa

Molecular line radiative transfer in protoplanetary disks: Monte Carlo simulations versus approximate methods

We analyze the line radiative transfer in protoplanetary disks using several approximate methods and a well-tested Accelerated Monte Carlo code. A low-mass flaring disk model with uniform as well as stratified molecular abundances is adopted. Radiative transfer in low and high rotational lines of CO, C18O, HCO+, DCO+, HCN, CS, and H2CO is simulated. The corresponding excitation temperatures, synthetic spectra, and channel maps are derived and compared to the results of the Monte Carlo calculations. A simple scheme that describes the conditions of the line excitation for a chosen molecular transition is elaborated. We find that the simple LTE approach can safely be applied for the low molecular transitions only, while it significantly overestimates the intensities of the upper lines. In contrast, the Full Escape Probability (FEP) approximation can safely be used for the upper transitions (J_{\rm up} \ga 3) but it is not appropriate for the lowest transitions because of the maser effect. In general, the molecular lines in protoplanetary disks are partly subthermally excited and require more sophisticated approximate line radiative transfer methods. We analyze a number of approximate methods, namely, LVG, VEP (Vertical Escape Probability) and VOR (Vertical One Ray) and discuss their algorithms in detail. In addition, two modifications to the canonical Monte Carlo algorithm that allow a significant speed up of the line radiative transfer modeling in rotating configurations by a factor of 10--50 are described.Comment: 47 pages, 12 figures, accepted for publication in Ap

Models of X-ray Photoionization in LMC X-4: Slices of a Stellar Wind

We show that the orbital variation in the UV P Cygni lines of the X-ray binary LMC X-4 results when X-rays photoionize nearly the entire region outside of the X-ray shadow of the normal star. We fit models to HST GHRS observations of N V and C IV P Cygni line profiles. Analytic methods assuming a spherically symmetric wind show that the wind velocity law is well-fit by v~(1-1/r)^beta, where beta is likely 1.4-1.6 and definitely <2.5. Escape probability models can fit the observed P Cygni profiles, and provide measurements of the stellar wind parameters. The fits determine Lx/Mdot=2.6+/-0.1 x10^43 erg/s/Msun yr, where Lx is the X-ray luminosity and Mdot is the mass-loss rate of the star. Allowing an inhomogeneous wind improves the fits. IUE spectra show greater P Cygni absorption during the second half of the orbit than during the first. We discuss possible causes of this effect.Comment: 56 pages, 12 figures, to be published in the Astrophysical Journa