A note on the convexity number for complementary prisms

In the geodetic convexity, a set of vertices $S$ of a graph $G$ is $\textit{convex}$ if all vertices belonging to any shortest path between two vertices of $S$ lie in $S$. The cardinality $con(G)$ of a maximum proper convex set $S$ of $G$ is the $\textit{convexity number}$ of $G$. The $\textit{complementary prism}$ $G\overline{G}$ of a graph $G$ arises from the disjoint union of the graph $G$ and $\overline{G}$ by adding the edges of a perfect matching between the corresponding vertices of $G$ and $\overline{G}$. In this work, we we prove that the decision problem related to the convexity number is NP-complete even restricted to complementary prisms, we determine $con(G\overline{G})$ when $G$ is disconnected or $G$ is a cograph, and we present a lower bound when $diam(G) \neq 3$.Comment: 10 pages, 2 figure

Relationship between expectation management and client retention in online cognitive behavioural therapy

Background: Engaging clients from the outset of psychotherapy is important for therapeutic success. However, there is little research evaluating therapists’ initial attempts to engage clients in the therapeutic process. This article reports retrospective analysis of data from a trial of online cognitive behavioural therapy (CBT) for depression. Qualitative and quantitative methods were used to evaluate how therapists manage clients’ expectations at the outset of therapy and its relationship with client retention in the therapeutic intervention. Aims: To develop a system to codify expectation management in initial sessions of online CBT and evaluate its relationship with retention. Method: Initial qualitative research using conversation analysis identified three communication practices used by therapists at the start of first sessions: no expectation management, some expectation management, and comprehensive expectation management. These findings were developed into a coding scheme that enabled substantial inter-rater agreement (weighted Kappa = 0.78; 95% CI: 0.52 to 0.94) and was applied to all trial data. Results: Adjusting for a range of client variables, primary analysis of data from 147 clients found comprehensive expectation management was associated with clients remaining in therapy for 1.4 sessions longer than those who received no expectation management (95% CI: -0.2 to 3.0). This finding was supported by a sensitivity analysis including an additional 21 clients (1.6 sessions, 95% CI: 0.2 to 3.1). Conclusions: Using a combination of qualitative and quantitative methods, this study suggests a relationship between expectation management and client retention in online CBT for depression, which has implications for professional practice. A larger prospective study would enable a more precise estimate of retention

Mott Transition, Compressibility Divergence and P-T Phase Diagram of Layered Organic Superconductors: An Ultrasonic Investigation

The phase diagram of the organic superconductor $\kappa$-(BEDT-TTF)$_2$Cu[N(CN)$_2$Cl has been investigated by ultrasonic velocity measurements under helium gas pressure. Different phase transitions were identified trough several elastic anomalies characterized from isobaric and isothermal sweeps. Our data reveal two crossover lines that end on the critical point terminating the first-order Mott transition line. When the critical point is approached along these lines, we observe a dramatic softening of the velocity which is consistent with a diverging compressibility of the electronic degrees of freedom.Comment: 4 pages, 5 figure

Evidence of Late Ediacaran Hyperextension of the Laurentian Iapetan Margin in the Birchy Complex, Baie Verte Peninsula, Northwest Newfoundland: Implications for the Opening of Iapetus, Formation of PeriLaurentian Microcontinents and Taconic – Grampian Orogenesis

The Birchy Complex of the Baie Verte Peninsula, northwestern Newfoundland, comprises an assemblage of mafic schist, ultramafic rocks, and metasedimentary rocks that are structurally sandwiched between overlying ca. 490 Ma ophiolite massifs of the Baie Verte oceanic tract and underlying metasedimentary rocks of the Fleur de Lys Supergroup of the Appalachian Humber margin. Birchy Complex gabbro yielded a Late Ediacaran U–Pb zircon ID–TIMS age of 558.3 ± 0.7 Ma, whereas gabbro and an intermediate tuffaceous schist yielded LA–ICPMS concordia zircon ages of 564 ± 7.5 Ma and 556 ± 4 Ma, respectively. These ages overlap the last phase of rift-related magmatism observed along the Humber margin of the northern Appalachians (565–550 Ma). The associated ultramafic rocks were exhumed by the Late Ediacaran and shed detritus into the interleaved sedimentary rocks. Psammite in the overlying Flat Point Formation yielded a detrital zircon population typical of the Laurentian Humber margin in the northern Appalachians. Age relationships and characteristics of the Birchy Complex and adjacent Rattling Brook Group suggest that the ultramafic rocks represent slices of continental lithospheric mantle exhumed onto the seafloor shortly before or coeval with magmatic accretion of mid-ocean ridge basalt-like mafic rocks. Hence, they represent the remnants of an ocean – continent transition zone formed during hyperextension of the Humber margin prior to establishment of a mid-ocean ridge farther outboard in the Iapetus Ocean. We propose that microcontinents such as Dashwoods and the Rattling Brook Group formed as a hanging wall block and an extensional crustal allochthon, respectively, analogous to the isolation of the Briançonnais block during the opening of the Alpine Ligurian–Piemonte and Valais oceanic seaways.Le complexe de Birchy de la péninsule de Baie Verte, dans le nord-ouest de Terre-Neuve, est constitué d’un assemblage de schistes mafiques, de roches ultramafiques et de métasédiments qui sont coincés entre des massifs ophiolitiques d’ascendance océanique de la Baie Verte au-dessus, et des métasédiments du Supergroupe de Fleur de Lys de la marge de Humber des Appalaches en-dessous. Le complexe de gabbro de Birchy a donné une datation U-Pb sur zircon ID-TIMS correspondant à la fin de l’Édiacarien, soit 558,3 ± 0,7 Ma, alors qu’un gabbro et un schiste tufacé intermédiaire montrent une datation LA-ICP-MS Concordia sur zircon de 564 ± 7,5 Ma et 556 ± 4 Ma, respectivement. Ces datations chevauchent la dernière phase de magmatisme de rift observée le long de la marge Humber des Appalaches du Nord (565-550 Ma). Les roches ultramafiques associées ont été exhumées vers la fin de l’Édiacarien et leurs débris ont été imbriqués dans des roches sédimentaires. Les psammites de la Formation de Flat Point susjacente ont donné une population de zircons détritiques typique de la marge laurentienne de Humber des Appalaches du Nord. Les relations chronologiques et les caractéristiques du complexe de Birchy et du groupe de Rattling Brook adjacent, permettent de penser que ces roches ultramafiques pourraient être des écailles de manteau lithosphérique continental qui auraient été exhumées sur le plancher océanique peu avant ou en même temps que l’accrétion magmatique de roches mafiques basaltiques de type dorsale médio-océanique. Par conséquent, elles seraient des vestiges d’une zone de transition océan-continent formée au cours de l’hyper-extension de la marge de Humber avant l’apparition d’une dorsale médio-océanique plus loin au large dans l’océan Iapétus. Nous proposons que des microcontinents comme de Dashwoods et du groupe de Rattling Brook ont constitués respectivement un bloc de toit et un allochtone crustal d’extension, de la même manière que le bloc Briançonnais a été isolé lors de l’ouverture des bras océaniques alpins de Ligurie-Piémont et de Valais.Fil: Van Staal, Cees R.. Geological Survey of Canada; CanadáFil: Chew, Dave M.. Trinity College Dublin; IrlandaFil: Zagorevski, Alexandre. Geological Survey of Canada; CanadáFil: Mcnicoll, Vicki. Geological Survey of Canada; CanadáFil: Hibbard, James. North Carolina State University; Estados UnidosFil: Skulski, Tom. Geological Survey of Canada; CanadáFil: Castonguay, Sébastien. Geological Survey of Canada; CanadáFil: Escayola, Monica Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos; ArgentinaFil: Sylvester, Paul J.. Memorial University Of Newfoundland; Canad

Сберегательное поведение в контексте исследования белорусской деловой культуры

Материалы X Международной научной конференции 25–26 мая 2017 г

A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models

Progressive kidney diseases are often associated with scarring of the kidney’s filtration unit, a condition called focal segmental glomerulosclerosis (FSGS). This scarring is due to loss of podocytes, cells critical for glomerular filtration, and leads to proteinuria and kidney failure. Inherited forms of FSGS are caused by Rac1-activating mutations, and Rac1 induces TRPC5 ion channel activity and cytoskeletal remodeling in podocytes. Whether TRPC5 activity mediates FSGS onset and progression is unknown. We identified a small molecule, AC1903, that specifically blocks TRPC5 channel activity in glomeruli of proteinuric rats. Chronic administration of AC1903 suppressed severe proteinuria and prevented podocyte loss in a transgenic rat model of FSGS. AC1903 also provided therapeutic benefit in a rat model of hypertensive proteinuric kidney disease. These data indicate that TRPC5 activity drives disease and that TRPC5 inhibitors may be valuable for the treatment of progressive kidney diseases.National Institutes of Health (U.S.) (Grant DK095045)National Institutes of Health (U.S.) (Grant DK099465)National Institutes of Health (U.S.) (Grant DK103658)National Institutes of Health (U.S.) (Grant DK083511)National Institutes of Health (U.S.) (Grant DK093746