Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis

The International Agency of Research in Cancer (IARC) has recently confirmed shift work as a type 2A carcinogen. The results presented in published epidemiological studies regarding prostate cancer are inconsistent and the association remains controversial. The aims of this study were: (a) to investigate the possible association between shift work and prostate cancer incidence, identifying possible sources of heterogeneity; and (b) to analyze the potential effect of publication bias. A search for cohort and case-control studies published from January 1980 to November 2019 was conducted. The quality of the articles was assessed using the Newcastle–Ottawa Scale. Pooled OR were calculated using random-effects models. Heterogeneity was evaluated using Cochran’s Q test and data were stratified by potential sources of heterogeneity. Publication bias was analyzed. Eighteen studies were included. No association was found between rotating/night-shift work and prostate cancer, pooled OR 1.07 (95%CI 0.99 to 1.15), I2 = 45.7%, p = 0.016. Heterogeneity was eliminated when only cohort studies (pooled OR 1.03; 95%CI 0.96 to 1.10; I2 = 18.9%, p = 0.264) or high-quality studies (pooled OR 0.99; 95%CI 0.89 to 1.08; I2 = 0.0%, p = 0.571) were considered. A publication bias was detected. An association between shift work and prostate cancer cannot be confirmed with the available current data. Future analytical studies assessing more objective homogeneous exposure variables still seem necessary

Percepción de los alumnos de enfermería de las unidades especiales a través de sus diarios

Conocer la experiencia clínica vivida por los alumnos de 4º curso de enfermería en las unidades de cuidados intensivos y reanimación. Potenciar el diario de prácticas clínicas como herramienta de reflexión durante los procesos de enseñanza aprendizaje clínico en las unidades de cuidados especiales. Introducir al alumno de prácticas clínicas en la rehumanización de los cuidados en unidades especiales (contextos clínicos cerrados y de alta incidencia tecnológica). Metodológicamente se emplearán, por una parte, los diarios de prácticas clínicas enfocados al problema planteado en esta investigación; por otra, se realizarán sesiones con grupos focales para debatir procesualmente, el problema de investigación a la luz de las narrativas vertidas en los diarios. Los principales resultados obtenidos ponen de manifiesto las siguientes categorías:-el miedo y la angustia vivido por los alumnos al comienzo en este tipo de unidades. La relevancia del tutor en este entorno. La importante labor desarrollada por un equipo multidisciplinar. La influencia de la tecnificación sin desatender los cuidados básicos. Ganan seguridad y confianza con el paso de los días siendo conscientes de sus limitaciones

El diario de prácticas clínicas en la unidad de cuidados intensivos

El objetivo de este trabajo se centra en conocer la experiencia clínica vivida por los alumnos de 4º curso de enfermería en las unidades de cuidados especiales. Para la obtención de los datos se empleará la utilización de una herramienta específica como es el diario de prácticas clínicas elaborado por los porpios alumnos donde se recojan las vivencias en las unidades especiales. Por otro lado se realizarán sesiones con grupos focales para debatir procesualmente, el problema de investigación a la luz de las narrativas vertidas en los diarios. Los resultados obtenidos ponen de manifiesto las siguientes categorías:-el miedo y la angustia vivido por los alumnos al comienzo en este tipo de unidades. La relevancia de la figura del tutor en este entorno. La labor desarrollada por un el equipo de soporte de la enseñanza clínica. La influencia de la tecnificación sin desatender los cuidados básicos y por último el aumento de la seguridad y confianza con el entorno con el paso de los día

El aprendizaje clínico en el EEES desde la perspectiva de los alumnos de enfermería

Objetivo Identificar las diferencias y semejanzas en el proceso de aprendizaje clínico de los diferentes países desde la perspectiva de los alumnos de enfermería. Material y Método -La metodología empleada es la propia de la Educación Comparada desarrollada, entre otros, por diferentes autores. Este proceso metodológico se vertebra a través de 4 fases: a) Descripción B) La fase de interpretación en la que los alumnos se plantean la necesidad de explicar las diferencias mediante el proceso de reflexión y el pensamiento crítico c) La yuxtaposición tiene como finalidad organizar los factores y elementos que inciden en su proceso de prácticas clínicas d) Comparación en los diferentes sistemas educativos (el de origen y el de destino de las prácticas). Empleando el diario de prácticas clínicas para la recogida de datos Análisis de Datos, para el análisis de los diarios se realizará un análisis de contenido, utilizando el software atlas ti para soporte en ayuda y categorización

Influence of Neospora caninum intra-specific variability in the outcome of infection in a pregnant BALB/c mouse model

Previous assays in pregnant animals have demonstrated the effect of different host factors and timing of infection on the outcome of neosporosis during pregnancy. However, the influence of Neospora caninum isolate itself has been poorly investigated. Here, we compared the effects on clinical outcome and vertical transmission observed in a pregnant mouse model following infection with 10 different N. caninum isolates. The isolates in our study included the Nc-Liv isolate and nine N. caninum isolates obtained from calves. Female BALB/c mice were inoculated with 2 × 106 tachyzoites at day 7 of pregnancy. Morbidity and mortality, in both dams and offspring during the course of infection, and transmission to progeny at day 30 postpartum were evaluated. The serum IgG1 and IgG2a production in dams were also examined. All dams showed elevated IgG1 and IgG2a responses, confirming N. caninum infection, although signs of disease were only exhibited in dams infected with 4 of the 10 isolates (Nc-Spain 4H, Nc-Spain 5H, Nc-Spain 7 and Nc-Liv). In neonates, clinical signs were observed in all N. caninum-infected groups, and neonatal mortality rates varied from greater than 95% with the isolates mentioned above to less than 32.5% with the other isolates. Vertical transmission rates, as assessed by parasite PCR-detection in neonate brains, also varied from 50% to 100% according to the isolate implicated. These results confirm the wide pathogenic and transmission variability of N. caninum. The intra-specific variability observed herein could help us explain the differences in the outcome of the infection in the natural host

Dynamics of isolated-photon plus jet production in pp collisions at root s=7 TeV with the ATLAS detector

The dynamics of isolated-photon plus jet production in pp collisions at a centre-of-mass energy of 7 TeV has been studied with the ATLAS detector at the LHC using an integrated luminosity of 37 pb(-1). Measurements of isolated-photon plus jet bin-averaged cross sections are presented as functions of photon transverse energy, jet transverse momentum and jet rapidity. In addition, the bin-averaged cross sections as functions of the difference between the azimuthal angles of the photon and the jet, the photon jet invariant mass and the scattering angle in the photon jet centre-of-mass frame have been measured. Next-to-leading-order QCD calculations are compared to the measurements and provide a good description of the data, except for the case of the azimuthal opening angle

Measurement of the cross-section for W boson production in association with b-jets in pp collisions at root s=7 TeV with the ATLAS detector

This paper reports a measurement of the W+b-jets (W+b+X and W+b (b) over bar +X) production cross-section in proton-proton collisions at a centre-of-mass energy of 7 TeV at the LHC. These results are based on data corresponding to an integrated luminosity of 4.6 fb(-1), collected with the ATLAS detector. Cross-sections are presented as a function of jet multiplicity and of the transverse momentum of the leading b-jet for both the muon and electron decay modes of the W boson. The W+b-jets cross-section, corrected for all known detector effects, is quoted in a limited kinematic range. Combining the muon and electron channels, the fiducial cross-section for W+b-jets is measured to be 7.1 +/- 0.5 (stat) +/- 1.4 (syst) pb, consistent with the next-to-leading order QCD prediction, corrected for non-perturbative and double-parton interactions (DPI) contributions, of 4.70 +/- 0.09 (stat) (+0.60)(-0.49) (scale) +/- 0.06 (PDF) +/- 0.16 (non-pert) (+0.52)(-0.38) (DPI) pb

Triggers for displaced decays of long-lived neutral particles in the ATLAS detector

A set of three dedicated triggers designed to detect long-lived neutral particles decaying throughout the ATLAS detector to a pair of hadronic jets is described. The efficiencies of the triggers for selecting displaced decays as a function of the decay position are presented for simulated events. The effect of pile-up interactions on the trigger efficiencies and the dependence of the trigger rate on instantaneous luminosity during the 2012 data-taking period at the LHC are discussed

Search for dark matter candidates and large extra dimensions in events with a jet and missing transverse momentum with the ATLAS detector

A search for new phenomena in events with a high-energy jet and large missing transverse momentum is performed using data from proton-proton collisions at root s = 7 TeV with the ATLAS experiment at the Large flatiron Collider. Four kinematic regions are explored using a dataset corresponding to an integrated luminosity of 4.7 fb(-1). No excess of events beyond expectations from Standard Model processes is observed, and limits are set on large extra dimensions and the pair production of dark matter particles

ATLAS search for new phenomena in dijet mass and angular distributions using pp collisions at root s=7 TeV

Mass and angular distributions of dijets produced in LHC proton-proton collisions at a centre-of-mass energy root s = 7TeV have been studied with the ATLAS detector using the full 2011 data set with an integrated luminosity of 4.8 fb(-1). Dijet masses up to similar to 4.0TeV have been probed. No resonance-like features have been observed in the dijet mass spectrum, and all angular distributions are consistent with the predictions of QCD. Exclusion limits on six hypotheses of new phenomena have been set at 95% CL in terms of mass or energy scale, as appropriate. These hypotheses include excited quarks below 2.83 TeV, colour octet scalars below 1.86TeV, heavy W bosons below 1.68 TeV, string resonances below 3.61 TeV, quantum black holes with six extra space-time dimensions for quantum gravity scales below 4.11 TeV, and quark contact interactions below a compositeness scale of 7.6 TeV in a destructive interference scenario