Experimental and numerical research activity on a packed bed TES system

This paper presents the results of experimental and numerical research activities on a packed bed sensible thermal energy storage (TES) system. The TES consists of a cylindrical steel tank filled with small alumina beads and crossed by air used as the heat transfer fluid. Experimental tests were carried out hile varying some operating parameters such as the mass flow rate, the inlet–outlet temperature thresholds and the aspect ratio (length over diameter). Numerical simulations were carried out using a one-dimensional model, specifically developed in the Matlab-Simulink environment and a 2D axisymmetric model based on the ANSYS-Fluent platform. Both models are based on a two-equation transient approach to calculate fluid and solid phase temperatures. Thermodynamic properties were considered to be temperature-dependent and, in the Computational Fluid Dynamics (CFD) model, variable porosity of the bed in the radial direction, thermal losses and the effective conductivity of the alumina beads were also considered. The simulation results of both models were compared to the experimental ones, showing good agreement. The one-dimensional model has the advantage of predicting the axial temperature distribution with a very low computational cost, but it does not allow calculation of the correct energy stored when the temperature distribution is strongly influenced by the wall. To overcome this problem a 2D CFD model was used in this work

Measuring the impact of reversible substations on energy efficiency in rail transport

open6Nowadays great interest is placed on the environmental issue. Greenhouse gas emissions are more than 50% higher than in 1990. European energy policy has been supporting efficient energy management in order to reduce the railway transport emissions by 50% within 2030. The railway stakeholders are encouraged to adopt technological solutions to foster energy efficiency. The electrodynamic braking combined with the adoption of reversible substations is one of the most promising solutions. In order to evaluate the impact of this innovative technology, a measurement campaign has been conducted on Metro de Madrid where a reversible substation was installed. In this paper, a preliminary analysis on the data acquired is presented. Traceable and accurate on-board train measurements of the energy flows and the losses are fundamental to quantify the impact of these new technologies and to carry out a survey on the efficiencies of the different vehicle components and on the strategies to reduce the energy consumption in the various operation modes. © IMEKO TC-4 2020.openCascetta F., Cipolletta G., Delle Femine A., Gallo D., Giordano D., Signorino D.Cascetta, F.; Cipolletta, G.; Delle Femine, A.; Gallo, D.; Giordano, D.; Signorino, D

FOLFIRINOX after first-line gemcitabine-based chemotherapy in advanced pancreatic cancer: a retrospective comparison with FOLFOX and FOLFIRI schedules

Background: Pancreatic adenocarcinoma is the fourth leading cause of cancer-related death. In cases with metastasis, the combination of 5-fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or gemcitabine-based chemotherapy regimens are considered the standard of care. However, the optimal sequence of these regimens is unclear. Methods: This retrospective study initially evaluated 186 patients with locally advanced/metastatic pancreatic cancer at three Italian institutions between February 2013 and October 2019. All patients had progressed after receiving gemcitabine-based first-line chemotherapy and were subsequently offered second-line FOLFIRINOX, FOLFOX-6, or FOLFIRI treatment. This study evaluated progression-free survival (PFS), overall survival from the start of second-line treatment (OS2), overall survival from the start of first-line treatment (OS1), and safety outcomes. Results: A total of 77 patients received ⩾4 cycles of second-line chemotherapy and were considered eligible: 15 patients received FOLFIRINOX, 32 patients received FOLFOX-6, and 30 patients received FOLFIRI. The FOLFIRINOX group had median PFS of 26.29 weeks and median OS2 of 47.86 weeks, while the FOLFIRI group had median PFS of 10.57 weeks and median OS2 of 25.00 weeks (p = 0.038). No significant differences were observed between the FOLFIRINOX and FOLFOX-6 groups in terms of PFS (26.29 weeks versus 23.07 weeks) or OS2 (47.86 weeks versus 42.00 weeks). The most common grade 3–4 toxicities were anemia, neutropenia, and thrombocytopenia, which occurred more frequently in the FOLFIRINOX and FOLFOX-6 groups. Conclusion: Relative to the FOLFIRI regimen, the FOLFIRINOX regimen had a favorable toxicity profile and better survival outcomes. No significant differences were observed relative to the FOLFOX-6 regimen

“Charge while driving” for electric vehicles: road traffic modeling and energy assessment

The aim of this research study is to present a method for analyzing the performance of the wireless inductive charge-while-driving (CWD) electric vehicles, from both traffic and energy points of view. To accurately quantify the electric power required from an energy supplier for the proper management of the charging system, a traffic simulation model is implemented. This model is based on a mesoscopic approach, and it is applied to a freight distribution scenario. Lane changing and positioning are managed according to a cooperative system among vehicles and supported by advanced driver assistance systems (ADAS). From the energy point of view, the analyses indicate that the traffic may have the following effects on the energy of the system: in a low traffic level scenario, the maximum power that should be supplied for the entire road is simulated at approximately 9 MW; and in a high level traffic scenario with lower average speeds, the maximum power required by the vehicles in the charging lane increases by more than 50

A multi-modal network approach to model public transport accessibility impacts of bicycle-train integration policies

In the Netherlands, the bicycle plays an important in station access and, to a lesser extent, in station egress. There is however fairly little knowledge in the potential effects of bicycle-train integration policies. The aim of this paper is to examine the impacts of bicycle-train integration policies on train ridership and job accessibility for public transport users.MethodsWe extended the Dutch National Transport Model (NVM) by implementing a detailed bicycle network linked to the public transport network, access/egress mode combinations and station specific access and egress penalties by mode and station type derived from a stated choice survey. Furthermore, the effects of several bicycletrain integration policy scenarios were examined for a case study for Randstad South, in the Netherlands, comprising a dense train network with 54 train stations.ConclusionsOur analysis shows that improving the quality of bicycle routes and parking can substantially increase train ridership and potential job accessibility for train users. Large and medium stations are more sensitive to improvements in bicycle-train integration policies, while small stations are more sensitive to improvements in the train level of service