728 research outputs found
Factores neurobiológicos y conductuales que influyen en el proceso de recaida de los pacientes heroinómanos correctamente desintoxicados
Memory Vulnerability: A Case for Delaying Error Reporting
To face future reliability challenges, it is necessary to quantify the risk
of error in any part of a computing system. To this goal, the Architectural
Vulnerability Factor (AVF) has long been used for chips. However, this metric
is used for offline characterisation, which is inappropriate for memory. We
survey the literature and formalise one of the metrics used, the Memory
Vulnerability Factor, and extend it to take into account false errors. These
are reported errors which would have no impact on the program if they were
ignored. We measure the False Error Aware MVF (FEA) and related metrics
precisely in a cycle-accurate simulator, and compare them with the effects of
injecting faults in a program's data, in native parallel runs. Our findings
show that MVF and FEA are the only two metrics that are safe to use at runtime,
as they both consistently give an upper bound on the probability of incorrect
program outcome. FEA gives a tighter bound than MVF, and is the metric that
correlates best with the incorrect outcome probability of all considered
metrics
Uso de fármacos psicoestimulantes en drogodependencias
El uso de medicamentos estimulantes es una cuestión de plena actualidad en psiquiatría, aunque su utilización y prescripción es controvertida . Fármacos como el metilfenidato, las anfetaminas, o el modafinilo están siendo utilizados y estudiados en distintas enfermedades psiquiátricas como el trastorno por déficit de atención e hiperactividad (TDAH), la dependencia de cocaína, en trastornos del sueño y en la depresión resistente. Todos estos fármacos tienen en común, igual que las drogas de abuso, que son medicamentos que actúan sobre el sistema dopaminérgico, que constituye la base neurobiológica del refuerzo fisiológico. Los estimulantes como el metilfenidato o el modafinilo son fármacos eficaces en el TDAH y han sido estudiados en el tratamiento de la dependencia de cocaína. En niños con TDAH el metilfenidato es un factor protector para el desarrollo de fármaco en la dependencia de cocaína, aunque son estudios preliminares, por lo que no se debe considerar que este totalmente demostrado que los fármacos psicoestimulantes sean eficaces en el tratamiento de esta dependencia. Aunque no son conocidos todos los mecanismos fisiopatológicos, parece crítico que el refuerzo, y por lo tanto el riesgo de dependencia, aparece cuando se producen incrementos rápidos dopaminérgicos y que los efectos terapéuticos aparecen cuando son lentos y mantenidos. Las características de uso a dosis bajas administradas por vía oral disminuyen el riesgo de abuso. Para realizar una adecuada prescripción es necesario aclarar, definitivamente, los mecanismos neuroquímicos en los que intervienen, y sus indicaciones en drogodependenciasStimulant drugs prescription is a controversial and current topic in psychiatry. Drugs such as methylphenidate, amphetamine compounds and modafinil have been trialed and used in attention deficit hyperactivity disorder (ADHD), sleep conditions, cocaine dependence and as an adjunct to antidepressants for depression. All these drugs, like stimulant drugs abuse, increase extracellular dopamine in the brain.This effect is associated with reinforcing as well as therapeutic effects. Methylphenidate and modafinil treatment of ADHD are associated with a reduced risk for later substance abuse among ADHD patients. There is evidence of the beneficial effects of the use of modafinil in cocaine dependence, altough there isn't conclusive evidence for the stimulants' efficacy in treatment of the stimulants' dependence. At this time, the physiopathology of drug abuse and dependence is unknown, but it's known that the very critical point is that the reinforcing effects are associated with rapid changes in dopamine increases, whereas the therapeutic effects are associated with slowly and smoothly rising dopamine levels, such as are achieved with low doses and oral administration. Due to this, it's necessary to study the neurobiological bases on which stimulants drugs are related, and their clinical use in dependence treatment
TaskPoint: sampled simulation of task-based programs
Sampled simulation is a mature technique for reducing simulation time of single-threaded programs, but it is not directly applicable to simulation of multi-threaded architectures. Recent multi-threaded sampling techniques assume that the workload assigned to each thread does not change across multiple executions of a program. This assumption does not hold for dynamically scheduled task-based programming models. Task-based programming models allow the programmer to specify program segments as tasks which are instantiated many times and scheduled dynamically to available threads. Due to system noise and variation in scheduling decisions, two consecutive executions on the same machine typically result in different instruction streams processed by each thread. In this paper, we propose TaskPoint, a sampled simulation technique for dynamically scheduled task-based programs. We leverage task instances as sampling units and simulate only a fraction of all task instances in detail. Between detailed simulation intervals we employ a novel fast-forward mechanism for dynamically scheduled programs. We evaluate the proposed technique on a set of 19 task-based parallel benchmarks and two different architectures. Compared to detailed simulation, TaskPoint accelerates architectural simulation with 64 simulated threads by an average factor of 19.1 at an average error of 1.8% and a maximum error of 15.0%.This work has been supported by the Spanish Government (Severo Ochoa grants SEV2015-0493, SEV-2011-00067), the Spanish Ministry of Science and Innovation
(contract TIN2015-65316-P), Generalitat de Catalunya (contracts 2014-SGR-1051 and 2014-SGR-1272), the RoMoL ERC Advanced Grant (GA 321253), the European HiPEAC Network of Excellence and the Mont-Blanc project (EU-FP7-610402 and EU-H2020-671697). M. Moreto has been partially supported by the Ministry of Economy and Competitiveness under Juan de la Cierva postdoctoral fellowship JCI-2012-15047. M. Casas is supported by the Ministry of Economy
and Knowledge of the Government of Catalonia and the Cofund programme of the Marie Curie Actions of the EUFP7 (contract 2013BP B 00243). T.Grass has been partially
supported by the AGAUR of the Generalitat de Catalunya (grant 2013FI B 0058).Peer ReviewedPostprint (author's final draft
Improving scalability of task-based programs
In a multi-core era, parallel programming allows further performance improvements, but with an important programmability cost. We envision that the best approach to parallel programming that can exceed the programability, parallelism, power, memory and reliability walls in Computer Architecture is a run-time approach.
Many traditional computer architecture concepts can be revisited and applied at the runtime layer in a completely transparent way to the programmer. The goal of this work is taking the computer architecture value prediction and data-prefetching concepts inside a runtime environment like OmpSs
Power efficient job scheduling by predicting the impact of processor manufacturing variability
Modern CPUs suffer from performance and power consumption variability due to the manufacturing process. As a result, systems that do not consider such variability caused by manufacturing issues lead to performance degradations and wasted power. In order to avoid such negative impact, users and system administrators must actively counteract any manufacturing variability.
In this work we show that parallel systems benefit from taking into account the consequences of manufacturing variability when making scheduling decisions at the job scheduler level. We also show that it is possible to predict the impact of this variability on specific applications by using variability-aware power prediction models. Based on these power models, we propose two job scheduling policies that consider the effects of manufacturing variability for each application and that ensure that power consumption stays under a system-wide power budget. We evaluate our policies under different power budgets and traffic scenarios, consisting of both single- and multi-node parallel applications, utilizing up to 4096 cores in total. We demonstrate that they decrease job turnaround time, compared to contemporary scheduling policies used on production clusters, up to 31% while saving up to 5.5% energy.Postprint (author's final draft
Factores neurobiológicos y conductuales que influyen en el proceso de recaida de los pacientes heroinómanos correctamente desintoxicados
Design trade-offs for emerging HPC processors based on mobile market technology
This is a post-peer-review, pre-copyedit version of an article published in The Journal of Supercomputing. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11227-019-02819-4High-performance computing (HPC) is at the crossroads of a potential transition toward mobile market processor technology. Unlike in prior transitions, numerous hardware vendors and integrators will have access to state-of-the-art processor designs due to Arm’s licensing business model. This fact gives them greater flexibility to implement custom HPC-specific designs. In this paper, we undertake a study to quantify the different energy-performance trade-offs when architecting a processor based on mobile market technology. Through detailed simulations over a representative set of benchmarks, our results show that: (i) a modest amount of last-level cache per core is sufficient, leading to significant power and area savings; (ii) in-order cores offer favorable trade-offs when compared to out-of-order cores for a wide range of benchmarks; and (iii) heterogeneous configurations help to improve processor performance and energy efficiency.Peer ReviewedPostprint (author's final draft
Graph partitioning applied to DAG scheduling to reduce NUMA effects
The complexity of shared memory systems is becoming more relevant as the number of memory domains increases, with different access latencies and bandwidth rates depending on the proximity between the cores and the devices containing the data. In this context, techniques to manage and mitigate non-uniform memory access (NUMA) effects consist in migrating threads, memory pages or both and are typically applied by the system software.
We propose techniques at the runtime system level to reduce NUMA effects on parallel applications. We leverage runtime system metadata in terms of a task dependency graph. Our approach, based on graph partitioning methods, is able to provide parallel performance improvements of 1.12X on average with respect to the state-of-the-art.This work has been partially supported by the RoMoL ERC Advanced Grant (GA 321253), the European HiPEAC Network of Excellence and the Spanish Government (contract
TIN2015-65316-P). I. Sánchez Barrera has been supported by the Spanish Government under Formación del Profesorado Universitario fellowship number FPU15/03612.Peer ReviewedPostprint (published version
Runtime-guided mitigation of manufacturing variability in power-constrained multi-socket NUMA nodes
This work has been supported by the Spanish Government (Severo Ochoa grants SEV2015-0493, SEV-2011-00067), by
the Spanish Ministry of Science and Innovation (contracts TIN2015-65316-P), by Generalitat de Catalunya (contracts 2014-SGR-1051 and 2014-SGR-1272), by the RoMoL ERC Advanced Grant (GA 321253) and the European HiPEAC Network of Excellence. M. Moretó has been partially supported by the Ministry of Economy and Competitiveness under Juan de la Cierva postdoctoral fellowship number JCI-2012-15047. M. Casas is supported by the Secretary for Universities and Research of the Ministry of Economy and Knowledge of the Government of Catalonia and the Cofund
programme of the Marie Curie Actions of the 7th R&D Framework Programme of the European Union (Contract 2013 BP B 00243). This work was also partially performed
under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344 (LLNL-CONF-689878).
Finally, the authors are grateful to the reviewers for their valuable comments, to the RoMoL team, to Xavier Teruel and Kallia Chronaki from the Programming Models group
of BSC and the Computation Department of LLNL for their technical support and useful feedback.Peer ReviewedPostprint (published version
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