A REDE DE SALAS DIGITAIS DO MERCOSUL E A PROMOÇÃO DA DIVERSIDADE CULTURAL

The MERCOSUR Network of Digital Cinema Theaters (RSDM), implemented by the MERCOSUR Specialized Meeting of Cinematographic and Audiovisual Authorities (RECAM), is the standing current policy proposed by the regional bloc regarding film distribution. In its creation agreement, the initiative considers the need to facilitate access to the block's audiovisual cultural diversity (MERCOSUR/GMC/RES. Nº28/15). By means of a bibliographic survey of the institutional development of RECAM and documents analysis, we pursue to contextualize the elaboration of its guidelines influenced by regional and international tendency of strong influence from UNESCO (VLASSIS 2016, MEJIA 2015, ALVES 2012); as well as to understand how cultural policy truly contributes to the promotion of cultural diversity in the region. Palabras Clave MERCOSURA Rede de Salas Digitais do MERCOSUL (RSDM), implementada pela Reunião Especializada de Autoridades Cinematográficas e Audiovisuais do MERCOSUL (RECAM), é a atual política de mais destaque proposta pelo bloco regional no âmbito da circulação audiovisual. Em sua resolução de criação, a iniciativa considera a necessidade de facilitar o acesso à Diversidade Cultural audiovisual do bloco (MERCOSUR/GMC/RES. Nº28/15). Através de levantamento bibliográfico sobre o desenvolvimento institucional da RECAM e análise de documentos, buscamos contextualizar suas diretrizes de elaboração em diálogo com uma tendência regional e internacional marcada por uma forte influência da UNESCO (VLASSIS, 2016; ALBORNOZ, 2015; MEJIA, 2009), assim como compreender como a política cultural pode contribuir para a promoção da Diversidade Cultural na região.A Rede de Salas Digitais do MERCOSUL (RSDM), implementada pela Reunião Especializada de Autoridades Cinematográficas e Audiovisuais do MERCOSUL (RECAM), é a atual política de mais destaque proposta pelo bloco regional no âmbito da circulação audiovisual. Em sua resolução de criação, a iniciativa considera a necessidade de facilitar o acesso à Diversidade Cultural audiovisual do bloco (MERCOSUR/GMC/RES. Nº28/15). Através de levantamento bibliográfico sobre o desenvolvimento institucional da RECAM e análise de documentos, buscamos contextualizar suas diretrizes de elaboração em diálogo com uma tendência regional e internacional marcada por uma forte influência da UNESCO (VLASSIS, 2016; ALBORNOZ, 2015; MEJIA, 2009), assim como compreender como a política cultural pode contribuir para a promoção da Diversidade Cultural na região

Reliability and validity of an FFQ for South American children and adolescents from the SAYCARE study

Objective:The purpose of this study was to analyse the reliability and validity of a semi-quantitative FFQ to assess food group consumption in South American children and adolescents.Design:The SAYCARE (South American Youth/Child cARdiovascular and Environmental) study is an observational, multicentre, feasibility study performed in a sample of 3-to 18-year-old children and adolescents attending private and public schools from six South American countries. Participants answered the FFQ twice with a two-week interval and three 24-h dietary recalls. Intraclass and Spearman''s correlations, weighted Cohen''s kappa (¿w), percentage of agreement and energy-adjusted Pearson''s correlation coefficients were calculated.Setting:Seven cities in South America (Buenos Aires, Lima, Medelin, Montevideo, Santiago, Sao Paulo and Teresina).Subjects:A sample of 200 children and 244 adolescents for reliability analyses and 252 children and 244 adolescents for validity analyses were included.Results:Depending on the food group, for children and adolescents, reliability analyses resulted in Spearman''s coefficients from 0·47 to 0·73, intraclass correlation coefficients from 0·66 to 0·99, ¿w coefficients from 0·35 to 0·63, and percentage of agreement between 72·75 and 83·52 %. In the same way, validity analyses resulted in Spearman''s coefficients from 0·17 to 0·37, energy-adjusted Pearson''s coefficients from 0·17 to 0·61, ¿w coefficients from 0·09 to 0·24, and percentages of agreement between 45·79 and 67·06 %.Conclusion:The SAYCARE FFQ achieved reasonable reliability and slight-moderate validity for almost all food groups intakes. Accordingly, it can be used for the purpose of ranking the intake of individuals within a population

Correlation between magnetic and crystal structural sublattices in palladium-doped FeRh alloys: Analysis of the metamagnetic phase transition driving forces

FeRh alloys doped with the third element exhibit a change in the lattice and magnetic subsystems, which are manifested in antiferromagnetic- ferromagnetic (AFM-FM) first-order phase transition temperature, the shrinkage of the temperate hysteresis under transition, and the reduction of the saturation magnetization. All aforementioned parameters are crucial for practical applications. To control them it is quite important to determine the driving forces of the metamagnetic transition and its origins. In this manuscript ab initio calculations and experimental studies results are presented, which demonstrate the correlation between the structural and magnetic properties of the Fe50Rh50−xPdx alloys. The qualitative analysis of the metamagnetic phase transition driving forces in palladium-doped FeRh alloys was performed to determine their contribution to the evolution of magnetic and lattice subsystems. In addition, the impact of the impurities phases together with its magnetic behavior on the AFM-FM phase transition was considered.Fil: Komlev, Aleksei S.. Lomonosov Moscow State University; RusiaFil: Karpenkov, Dmitriy Y.. National University of Science and Technology; Rusia. Lomonosov Moscow State University; RusiaFil: Gimaev, Radel R.. Lomonosov Moscow State University; RusiaFil: Chirkova, Alisa. Institute for Materials Science; AlemaniaFil: Akiyama, Ayaka. Hirosaki University; JapónFil: Miyanaga, Takafumi. Hirosaki University; JapónFil: Hupalo, Marcio Ferreira. Universidade Estadual do Ponta Grossa; BrasilFil: Aguiar, D.J.M.. Universidade Federal do Paraná; BrasilFil: Carvalho, Alexandre Magnus G.. Universidade Estadual de Maringá; Brasil. Universidade Federal de Sao Paulo; BrasilFil: Jiménez, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; ArgentinaFil: Cabeza, Gabriela Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; ArgentinaFil: Zverev, Vladimir I.. Lomonosov Moscow State University; RusiaFil: Perov, Nikolai S.. Lomonosov Moscow State University; Rusi

Critical Discourse Analysis of Media Texts

El volumen presenta una panorámica del Análisis Crítico del Discurso de los textos mediáticos. El Análisis Crítico del Discurso es un modelo que parte de la Lingüística Crítica, basada a su vez en la Gramática Funcional de M. A. K. Halliday. En el volumen se resumen los principales enfoques de esta teoría. El volumen está compuesto de diversos artículos en los que se analizan diferentes casos concretos de los discursos de los medios de comunicación de masas (discurso informativo, discurso publicitario, discurso televisivo y discurso fílmico)The volume presents an overview of Critical Discourse Analysis of media texts. Critical Discourse Analysis is a framework departing from Critical Linguistics, which is based, in turn, on Functional Grammar as developed by M. A. K. Halliday. In this volume several approaches to Critical Discourse Analysis are summed up. In addition, the volume is composed by several papers where diverse concrete cases of media discourses are analysed (news discourse, advertisement discourse, television discourse and filmic discourse

Anticancer activity of 7-epiclusianone, a benzophenone from Garcinia brasiliensis, in glioblastoma

Abstract\ud \ud Background\ud Glioblastoma is the most common tumor of the central nervous system and one of the hardest tumors to treat. Consequently, the search for novel therapeutic options is imperative. 7-epiclusianone, a tetraprenylated benzophenone isolated from the epicarp of the native plant Garcinia brasiliensis, exhibits a range of biological activities but its prospect anticancer activity is underexplored. Thus, the aim of the present study was to evaluate the influence of 7-epiclusianone on proliferation, clonogenic capacity, cell cycle progression and induction of apoptosis in two glioblastoma cell lines (U251MG and U138MG).\ud \ud \ud Methods\ud Cell viability was measured by the MTS assay; for the clonogenic assay, colonies were stained with Giemsa and counted by direct visual inspection; For cell cycle analysis, cells were stained with propidium iodide and analyzed by cytometry; Cyclin A expression was determined by immunoblotting; Apoptotic cell death was determined by annexin V fluorescein isothiocyanate labeling and Caspase-3 activity in living cells.\ud \ud \ud Results\ud Viability of both cell lines was drastically inhibited; moreover, the colony formation capacity was significantly reduced, demonstrating long-term effects even after removal of the drug. 7-epiclusianone treatment at low concentrations also altered cell cycle progression, decreased the S and G2/M populations and at higher concentrations increased the number of cells at sub-G1, in concordance with the increase of apoptotic cells.\ud \ud \ud Conclusion\ud The present study demonstrates for the first time the anticancer potential of 7-epiclusianone against glioblastoma cells, thus meriting its further investigation as a potential therapeutic agent.This study was supported by the following Public Research Agencies:\ud FAPEMIG, FAPESP, CNPq and CAPES

Artistas sobre outras obras

Às vezes as palavras podem ser escondidas antes de ser ditas, cabendo ao artista, ou ao poeta, a capacidade de as revelar. São coisas difíceis, pois tratam-se de coisas de difícil acesso, apenas franqueadas pelos poetas e artistas. E estes artistas, convocados por outros artistas, se anunciam vivos pelo olhar da afinidade, pela convergência para lá do visível, pela cumplicidade assinalada. Assim se reunem os artigos deste número da revista Estúdio 23.info:eu-repo/semantics/publishedVersio

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

práticas artísticas no ensino básico e secundário

A Educação Artística joga-se em muito mais locais que no ensino formal. As oportunidades formativas têm sido aproveitadas por museus, bibliotecas, centros culturais, exposições, festivais, associações e plataformas culturais, eventos, plataformas de disseminação artística, edições. Os artistas individuais têm vindo a integrar as dinâmicas relacionais e de criação de públicos nas suas obras, ao convocarem as audiências e implicarem o espectador. O terreno é limitado apenas pela imaginação, e as oportunidades de convocação alargam-se aos novos conteúdos e plataformas digitais, a par com a valorização do que é local e identitário: a revolução pode fazer-se pela cidadania.info:eu-repo/semantics/publishedVersio

Mapping density, diversity and species-richness of the Amazon tree flora

Using 2.046 botanically-inventoried tree plots across the largest tropical forest on Earth, we mapped tree species-diversity and tree species-richness at 0.1-degree resolution, and investigated drivers for diversity and richness. Using only location, stratified by forest type, as predictor, our spatial model, to the best of our knowledge, provides the most accurate map of tree diversity in Amazonia to date, explaining approximately 70% of the tree diversity and species-richness. Large soil-forest combinations determine a significant percentage of the variation in tree species-richness and tree alpha-diversity in Amazonian forest-plots. We suggest that the size and fragmentation of these systems drive their large-scale diversity patterns and hence local diversity. A model not using location but cumulative water deficit, tree density, and temperature seasonality explains 47% of the tree species-richness in the terra-firme forest in Amazonia. Over large areas across Amazonia, residuals of this relationship are small and poorly spatially structured, suggesting that much of the residual variation may be local. The Guyana Shield area has consistently negative residuals, showing that this area has lower tree species-richness than expected by our models. We provide extensive plot meta-data, including tree density, tree alpha-diversity and tree species-richness results and gridded maps at 0.1-degree resolution