Time for some changes to ICIS? Reflections on our highest-quality conference

© 2017 by the Association for Information Systems. In this commentary, we reflect on the program chair experience of ICIS 2015 to pass on some useful organizational memory for the IS community at large. We also reflect on volunteer effort required for a high-quality conference and the challenges of maintaining quality over a diverse and dispersed reviewing effort. We ask whether we can count on this volunteer effort in a changing higher education context where universities value volunteer effort or service less than promotion and tenure. We make several wide-ranging recommendations to preserve organizational memory and ensure the ongoing excellence of ICIS. Finally, we elaborate on some hard questions about whether the current conference model is fit for purpose and consider alternative models for our high-quality conference

Assistive tool for collaborative learning of conceptual structures

The final publication is available at link.springer.comThere is a demand for computational methods assisting learners to generate relevantassociations for current context. Many concepts in natural language have ambiguous meaningsimplying alternative ways to define associations for them. It is crucial to develop collaborativemethods that support free experiments with promising conceptual structures in learning.Methods for evaluating these structures in respect to the person’s needs are also required. Wepropose a new collaborative ideation scheme and based on that we have implemented anassistive tool for learning conceptual structures in a collaborative Web environment.Peer reviewe

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids. In Escherichia coli, immunity depends on a ribonucleoprotein complex called Cascade. Here we present the composition and low-resolution structure of Cascade and show how it recognizes double-stranded DNA (dsDNA) targets in a sequence-specific manner. Cascade is a 405-kDa complex comprising five functionally essential CRISPR-associated (Cas) proteins (CasA1B2C6D1E1) and a 61-nucleotide CRISPR RNA (crRNA) with 5′-hydroxyl and 2′,3′-cyclic phosphate termini. The crRNA guides Cascade to dsDNA target sequences by forming base pairs with the complementary DNA strand while displacing the noncomplementary strand to form an R-loop. Cascade recognizes target DNA without consuming ATP, which suggests that continuous invader DNA surveillance takes place without energy investment. The structure of Cascade shows an unusual seahorse shape that undergoes conformational changes when it binds target DNA.

Schools and the legacy of hybrid buildings

Learning from the past, collecting data on the Italian condition of school buildings, our R&D work aimed to question the design process of school buildings in Italy introducing an innovative model of school, which turned the conventional and isolated, mono-functional and rigid school buildings into interior urban public spaces and porous community hubs to empower the communities around them and to become manifestos of sustainability. Through some built examples of school buildings designed in Italy, the paper discusses the outputs and impact of the introduction of new design layouts, participation projects with different stakeholders and sustainability. The research has guided the introduction of the new Italian guide-lines for school building design, approved in 2013. A future perspective to be explored is the reconsideration of exporting the strategy in different contexts and to design reconsider other public infrastructures turning the mono-functional use of public buildings into hybrid and multifunctional ones

A review of the polygraph: history, methodology and current status

The history of research into psychophysiological measurements as an aid to detecting lying, widely known as the ‘lie detector’ or polygraph is the focus of this review. The physiological measurements used are detailed and the debates that exist in regards to its role in the investigative process are introduced. Attention is given to the main polygraph testing methods, namely the Comparative Question Test and the Concealed Information Test. Discussion of these two central methods, their uses and problems forms the basis of the review. Recommendations for future research are made specifically in regards to improving current polygraph technology and exploring the role of the polygraph in combination with other deception detection techniques

Does Childhood Executive Function Predict Adolescent Functional Outcomes in Girls with ADHD?

We prospectively followed an ethnically and socioeconomically diverse sample of preadolescent girls with ADHD (n = 140) and matched comparison girls (n = 88) over a period of 5 years, from middle childhood through early/mid-adolescence. Our aim was to examine the ability of measures of childhood executive function (EF) to predict functional outcomes in adolescence. Measures of neuropsychological functioning comprised the childhood predictors, with academic, social, and global functioning serving as adolescent criterion measures. Results indicated that childhood EF predicted (a) academic achievement and social functioning across our entire sample (independent of diagnostic group status) and (b) global functioning only in girls with ADHD (independent of IQ). These results highlight the non-specificity of EF deficits and suggest the importance of assessing and developing interventions that target EF impairments, particularly in those at high-risk for negative outcomes, in order to prevent long-term difficulties across a range of important functional domains

Are motor inhibition and cognitive flexibility dead ends in ADHD?

Contains fulltext : 53518.pdf (publisher's version ) (Closed access)Executive dysfunction has been postulated as the core deficit in ADHD, although many deficits in lower order cognitive processes have also been identified. By obtaining an appropriate baseline of lower order cognitive functioning light may be shed on as to whether executive deficits result from problems in lower order and/or higher order cognitive processes. We examined motor inhibition and cognitive flexibility in relation to a baseline measure in 816 children from ADHD and control families. Multiple children in a family were tested in order to examine the familiality of the measures. No evidence was found for deficits in motor inhibition or cognitive flexibility in children with ADHD or their nonaffected siblings: Compared to their baseline speed and accuracy of responding, children with ADHD and their (non)affected siblings were not disproportionally slower or inaccurate when demands for motor inhibition or cognitive flexibility were added to the task. However, children with ADHD and their (non)affected siblings were overall less accurate than controls, which could not be attributed to differences in response speed. This suggests that inaccuracy of responding is characteristic of children having (a familial risk for) ADHD. Motor inhibition and cognitive flexibility as operationalized with mean reaction time were found to be familial. It is concluded that poorer performance on executive tasks in children with ADHD and their (non)affected siblings may result from deficiencies in lower order cognitive processes and not (only) from higher order cognitive processes/executive functions