751 research outputs found
Magnetic chemically peculiar stars
Chemically peculiar (CP) stars are main-sequence A and B stars with
abnormally strong or weak lines for certain elements. They generally have
magnetic fields and all observables tend to vary with the same period.
Chemically peculiar stars provide a wealth of information; they are natural
atomic and magnetic laboratories. After a brief historical overview, we discuss
the general properties of the magnetic fields in CP stars, describe the oblique
rotator model, explain the dependence of the magnetic field strength on the
rotation, and concentrate at the end on HgMn stars.Comment: 9 pages, 4 figures, 2 tables, chapter in "Determination of
Atmospheric Parameters of B-, A-, F- and G-Type Stars", Springer (2014), eds.
E. Niemczura, B. Smalley, W. Pyc
Comprehensive study of the magnetic stars HD 5797 and HD 40711 with large chromium and iron overabundances
We present the results of a comprehensive study of the chemically peculiar
stars HD 5797 and HD 40711. The stars have the same effective temperature, Teff
= 8900 K, and a similar chemical composition with large iron (+1.5 dex) and
chromium (+3 dex) overabundances compared to the Sun. The overabundance of
rare-earth elements typically reaches +3 dex. We have measured the magnetic
field of HD 5797. The longitudinal field component Be has been found to vary
sinusoidally between -100 and +1000 G with a period of 69 days. Our estimate of
the evolutionary status of the stars suggests that HD 5797 and HD 40711, old
objects with an age t \approx 5 \times 108 yr, are near the end of the core
hydrogen burning phase.Comment: 26 pages, 5 Encapsulated Postscript figure
Effects of Chronic Atrial Fibrillation on Active and Passive Force Generation in Human Atrial Myofibrils
Rationale: Chronic atrial fibrillation (cAF) is associated with atrial contractile dysfunction. Sarcomere remodeling may contribute to this contractile disorder.
Objective: Here, we use single atrial myofibrils and fast solution switching techniques to directly investigate the impact of cAF on myofilament mechanical function eliminating changes induced by the arrhythmia in atrial myocytes membranes and extracellular components. Remodeling of sarcomere proteins potentially related to the observed mechanical changes is also investigated.
Methods and Results: Myofibrils were isolated from atrial samples of 15 patients in sinus rhythm and 16 patients with cAF. Active tension changes following fast increase and decrease in [Ca2+] and the sarcomere length\u2013passive tension relation were determined in the 2 groups of myofibrils. Compared to sinus rhythm myofibrils, cAF myofibrils showed (1) a reduction in maximum tension and in the rates of tension activation and relaxation; (2) an increase in myofilament Ca2+ sensitivity; (3) a reduction in myofibril passive tension. The slow \u3b2-myosin heavy chain isoform and the more compliant titin isoform N2BA were up regulated in cAF myofibrils. Phosphorylation of multiple myofilament proteins was increased in cAF as compared to sinus rhythm atrial myocardium.
Conclusions: Alterations in active and passive tension generation at the sarcomere level, explained by translational and post-translational changes of multiple myofilament proteins, are part of the contractile dysfunction of human cAF and may contribute to the self-perpetuation of the arrhythmia and the development of atrial dilatation
Optical properties of structurally-relaxed Si/SiO superlattices: the role of bonding at interfaces
We have constructed microscopic, structurally-relaxed atomistic models of
Si/SiO superlattices. The structural distortion and oxidation-state
characteristics of the interface Si atoms are examined in detail. The role
played by the interface Si suboxides in raising the band gap and producing
dispersionless energy bands is established. The suboxide atoms are shown to
generate an abrupt interface layer about 1.60 \AA thick. Bandstructure and
optical-absorption calculations at the Fermi Golden rule level are used to
demonstrate that increasing confinement leads to (a) direct bandgaps (b) a blue
shift in the spectrum, and (c) an enhancement of the absorption intensity in
the threshold-energy region. Some aspects of this behaviour appear not only in
the symmetry direction associated with the superlattice axis, but also in the
orthogonal plane directions. We conclude that, in contrast to Si/Ge, Si/SiO
superlattices show clear optical enhancement and a shift of the optical
spectrum into the region useful for many opto-electronic applications.Comment: 11 pages, 10 figures (submitted to Phys. Rev. B
Accurate fundamental parameters for 23 bright solar-type stars
We combine results from interferometry, asteroseismology and spectroscopy to
determine accurate fundamental parameters of 23 bright solar-type stars, from
spectral type F5 to K2 and luminosity classes III to V. For some stars we can
use direct techniques to determine the mass, radius, luminosity and effective
temperature, and we compare with indirect methods that rely on photometric
calibrations or spectroscopic analyses. We use the asteroseismic information
available in the literature to infer an indirect mass with an accuracy of 4-15
percent. From indirect methods we determine luminosity and radius to 3 percent.
For Teff we find a slight offset of -40+-20 K between the spectroscopic method
and the direct method, meaning the spectroscopic temperatures are too high.
From the spectroscopic analysis we determine the detailed chemical
composition for 13 elements, including Li, C and O. We find no significant
offset between the spectroscopic surface gravity and the value from combining
asteroseismology with radius estimates. From the spectroscopy we also determine
vsini and we present a new calibration of macro- and microturbulence. From the
comparison between the results from the direct and spectroscopic methods we
claim that we can determine Teff, log g, and [Fe/H] with absolute accuracies of
80 K, 0.08 dex, and 0.07 dex. The indirect methods are important to obtain
reliable estimates of the fundamental parameters of relatively faint stars when
interferometry cannot be used. Our study is the first to compare direct and
indirect methods for a large sample of stars, and we conclude that indirect
methods are valid, although slight corrections may be needed.Comment: Accepted by MNRAS. Abstract abridge
Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease
Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort. Methods: 250 IBD patients were retrospectively analyzed for iron deficiency and iron deficiency anemia. A subgroup was analyzed regarding efficacy and side effects of iron supplementation with ferric carboxymaltose. Results: In the cohort (n = 250), 54.4% of the patients had serum iron levels 60 mu g/dl, 61.6% had ferritin >100 ng/ml, and 90.7% reached Hb >12/13 g/dl at follow-up (p < 0.0001 for all parameters vs. pretreatment values). The most frequent adverse event was a transient increase of liver enzymes with male gender as risk factor (p = 0.008, OR 8.62, 95% CI 1.74-41.66). Conclusions: Iron deficiency and anemia are frequent in IBD patients. Treatment with ferric carboxymaltose is efficious, safe and well tolerated in iron-deficient IBD patients. Copyright (C) 2011 S. Karger AG, Base
Magnetic fields and chemical peculiarities of the very young intermediate-mass binary system HD 72106
The recently discovered magnetic Herbig Ae and Be stars may provide
qualitatively new information about the formation and evolution of magnetic Ap
and Bp stars. We have performed a detailed investigation of one particularly
interesting binary system with a Herbig Ae secondary and a late B-type primary
possessing a strong, globally ordered magnetic field. Twenty high-resolution
Stokes V spectra of the system were obtained with the ESPaDOnS instrument
mounted on the CFHT. In these observations we see clear evidence for a magnetic
field in the primary, but no evidence for a magnetic field in the secondary. A
detailed abundance analysis was performed for both stars, revealing strong
chemical peculiarities in the primary and normal chemical abundances in the
secondary. The primary is strongly overabundant in Si, Cr, and other iron-peak
elements, as well as Nd, and underabundant in He. The primary therefore appears
to be a very young Bp star. In this context, line profile variations of the
primary suggest non-uniform lateral distributions of surface abundances.
Interpreting the 0.63995 +/- 0.00009 day variation period of the Stokes I and V
profiles as the rotational period of the star, we have modeled the magnetic
field geometry and the surface abundance distributions of Si, Ti, Cr and Fe
using Magnetic Doppler Imaging. We derive a dipolar geometry of the surface
magnetic field, with a polar strength of 1230 G and an obliquity of 57 degrees.
The distributions Ti, Cr and Fe are all qualitatively similar, with an
elongated patch of enhanced abundance situated near the positive magnetic pole.
The Si distribution is somewhat different, and its relationship to the magnetic
field geometry less clear.Comment: Accepted by Monthly Notices of the Royal Astronomical Society,
September 2008. 15 pages, 10 figure
Prospects for asteroseismology
The observational basis for asteroseismology is being dramatically
strengthened, through more than two years of data from the CoRoT satellite, the
flood of data coming from the Kepler mission and, in the slightly longer term,
from dedicated ground-based facilities. Our ability to utilize these data
depends on further development of techniques for basic data analysis, as well
as on an improved understanding of the relation between the observed
frequencies and the underlying properties of the stars. Also, stellar modelling
must be further developed, to match the increasing diagnostic potential of the
data. Here we discuss some aspects of data interpretation and modelling,
focussing on the important case of stars with solar-like oscillations.Comment: Proc. HELAS Workshop on 'Synergies between solar and stellar
modelling', eds M. Marconi, D. Cardini & M. P. Di Mauro, Astrophys. Space
Sci., in the press Revision: correcting abscissa labels on Figs 1 and
Extracorporeal Membrane Oxygenation for Graft Dysfunction Early After Heart Transplantation: A Systematic Review and Meta-analysis
Introduction: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a prevailing option for the management of severe early graft dysfunction. This systematic review and individual patient data (IPD) meta-analysis aims to evaluate (1) mortality, (2) rates of major complications, (3) prognostic factors, and (4) the effect of different VA-ECMO strategies on outcomes in adult heart transplant (HT) recipients supported with VA-ECMO. Methods and Results: We conducted a systematic search and included studies of adults (≥18 years) who received VA-ECMO during their index hospitalization after HT and reported on mortality at any timepoint. We pooled data using random effects models. To identify prognostic factors, we analysed IPD using mixed effects logistic regression. We assessed the certainty in the evidence using the GRADE framework. We included 49 observational studies of 1477 patients who received VA-ECMO after HT, of which 15 studies provided IPD for 448 patients. There were no differences in mortality estimates between IPD and non-IPD studies. The short-term (30-day/in-hospital) mortality estimate was 33% (moderate certainty, 95% confidence interval [CI] 28%–39%) and 1-year mortality estimate 50% (moderate certainty, 95% CI 43%–57%). Recipient age (odds ratio 1.02, 95% CI 1.01–1.04) and prior sternotomy (OR 1.57, 95% CI 0.99–2.49) are associated with increased short-term mortality. There is low certainty evidence that early intraoperative cannulation and peripheral cannulation reduce the risk of short-term death. Conclusions: One-third of patients who receive VA-ECMO for early graft dysfunction do not survive 30 days or to hospital discharge, and one-half do not survive to 1 year after HT. Improving outcomes will require ongoing research focused on optimizing VA-ECMO strategies and care in the first year after HT
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