Matching unrelated stimuli with same discriminative functions: training order effects

Previous research has shown that after training simple discriminations (A1+/A2-, B1+/B2-), bringing these tasks under conditional control (J1-A1, J2-A2) leads to transfer of discriminative control (J1+/J2-) and to generalized matching on the basis of same discriminative functions (e.g. J1-B1, J2-B2). The same occurs when conditional discriminations are trained (D1-E1, D2-E2; F1-G1, F2-G2). When the subjects are then trained to demonstrate correct relations (D1-E1, D2-E2) when given X1 and to demonstrate incorrect relations when given X2 (XD-E), transfer of discriminative control (X1+/X2-) and generalized matching on the basis of same discriminative functions emerges (e.g. X1F1-G1, X2F1-G2). The present study investigated if these performances are dependent on the training and/or testing order. In Experiment 1, the lower-order contingency tasks were trained before the higher-order contingency tasks (A1+/A2-, B1+/B2- before J-A, and D-E, F-G before XD-E). Half the subjects received the J-B test before the more complex XF-G test (Condition A), while for the other subjects, this testing order was reversed (Condition B). Finally, all subjects received additional tests in which they were given the opportunity to demonstrate the discriminative properties of the J and X stimuli (J1+/J2-, X1+/X2-), and to match the A, J, and X stimuli with newly introduced stimuli of same discriminative properties (e.g. J1-POLITE, J2-RUDE). Experiment 2 was the same except that the training order was reversed (J-A before A1+/A2-, B1+/B2-, and XD-E before D-E, F-G). The results were affected by the training order but not by the testing order. Transfer of discriminative functions and generalized matching on the basis of same functions only occurred reliably when the lower-order contingency tasks were trained first. A stimulus-control account of the data is offered

Equivalence-equivalence as a model of analogy: Further analyses

Equivalence-equivalence is assumed when training of A-B and A-C matching tasks not only leads to matching same-class B and C stimuli but also to matching BC compounds with same-class elements (e.g., B1 C1-B2C2) and with different-class elements (e.g., B1C2-B2C3). Like classical analogies (a : b :: c : d), equivalence-equivalence requires matching same functional relations. Experiments 1 to 4 examined equivalence-equivalence in 5-year-old children. In each experiment, subjects were tested for equivalence-equivalence before equivalence and, if they did not show equivalence-equivalence, also after the equivalence test. The experiments included various procedural arrangements designed to facilitate equivalence-equivalence, all of which failed. Only 8/18 children showed equivalence-equivalence, 2 before (11%) and 6 after equivalence (33%), irrespective of the facilitative procedures that were used. Adults served in Experiment 5. This experiment was the same as Experiments 1 through 4 but without facilitative arrangements. All adults showed equivalence-equivalence, most of them before equivalence. These and previously collected findings (Carpentier, Smeets, & Barnes-Holmes, 2002) suggest that equivalence-equivalence is an age-related performance similar to that which has been reported in earlier developmental studies on classical analogies. Yet, one should be cautious using equivalence-equivalence as a model for analogical reasoning. The testing procedures in both types of tasks are sufficiently different to permit the performances to be based on different behavioral processes

Risk factors for borderline personality disorder in treatment seeking patients with a substance use disorder: An international multicenter study

Borderline personality disorder (BPD) and substance use disorders (SUDs) often co-occur, partly because they share risk factors. In this international multicenter study, risk factors for BPD were examined for SUD patients. In total, 1,205 patients were comprehensively examined by standardized interviews and questionnaires on psychiatric diagnosis and risk factors, and it was found that 1,033 (85.7%) had SUDs without BPD (SUD) and 172 (14.3%) had SUD with BPD (SUD + BPD). SUD + BPD patients were significantly younger, more often females and more often diagnosed with comorbid adult attention deficit/hyperactivity disorder. SUD + BPD patients did not differ from SUD patients on most risk factors typical for SUD such as maternal use of drugs during pregnancy or parents having any SUD. However, SUD + BPD patients did have a higher risk of having experienced emotional and physical abuse, neglect, or family violence in childhood compared to SUD patients, suggesting that child abuse and family violence are BPD-specific risk factors in patients with SUDs

Validity of the ADHD module of the Mini International Neuropsychiatric Interview PLUS for screening of adult ADHD in treatment seeking substance use disorder patients: ADHD screening with MINI-Plus

Az ADHD szűrési lehetőségei a Mini-plus mérőeszköz segítségéve

Persistence and Subtype Stability of ADHD Among Substance Use Disorder Treatment Seekers

OBJECTIVE: To examine ADHD symptom persistence and subtype stability among substance use disorder (SUD) treatment seekers. METHOD: In all, 1,276 adult SUD treatment seekers were assessed for childhood and adult ADHD using Conners' Adult ADHD Diagnostic Interview for Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV; CAADID). A total of 290 (22.7%) participants met CAADID criteria for childhood ADHD and comprise the current study sample. RESULTS: Childhood ADHD persisted into adulthood in 72.8% (n = 211) of cases. ADHD persistence was significantly associated with a family history of ADHD, and the presence of conduct disorder and antisocial personality disorder. The combined subtype was the most stable into adulthood (78.6%) and this stability was significantly associated with conduct disorder and past treatment of ADHD. CONCLUSION: ADHD is highly prevalent and persistent among SUD treatment seekers and is associated with the more severe phenotype that is also less likely to remit. Routine screening and follow-up assessment for ADHD is indicated to enhance treatment management and outcomes

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.

RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Douze hommes en colère - Architecture du secret du délibéré.

« Boy, how do ya like that ?... All right, who was it ? Come on ! I wanna know. »[1]             Douze hommes en colère, film culte de Sidney Lumet sorti en 1957, met en scène un huis clos dans lequel douze jurés, parmi lesquels Henry Fonda (juré n° 8), doivent se prononcer quant à la culpabilité d’un jeune homme accusé de parricide. Ce huis clos par nature pourrait-on dire – dès que les jurés entrent dans la salle de délibéré on peut entendre la serrure de la pièce être verrouillée par le ga..

L'homme qui voulait vivre sa vie : le suicide est-il toujours condamné par la peine de mort ?

L’homme qui voulait vivre sa vie (Éric Lartigau, 2010) nous propose de rencontrer Paul Exben (Romain Duris), brillant avocat en droit des affaires qui mène la vie qu’il n’a jamais souhaité vivre mais que son père a toujours souhaité qu’il vive : marié, père de deux enfants, vivant dans une grande maison en banlieue avec sa femme, douce mais devenue détestable. La lourdeur de la réalisation proposée par Éric Lartigau tend à souligner la pesanteur de cette vie que Paul n’a jamais souhaitée, lui..