Granitoides del Centro Oeste de la Provincia de Salamanca. Clasificación y correlación

[Resumen] En las rocas graníticas de la zona centro-oeste de la provincia de Salamanca, pueden establecerse tres grupos. Los dos primeros formados por leucogranitos y granitos de dos micas de tendencia alcalina, y el tercero por granitos de tendencia calcoalcalina que evolucionan hacia términos alcalinos convergentes con los anteriores. La descripción de estos granitoides así como su correlación con las clasificaciones existentes de dominios regionales, son el objeto del presente trabajo

Implementation of a moving finite element mesh within the catenary-pantograph dynamic interaction

En este artículo se presenta la aplicación tecnológica a la interacción dinámica catenaria-pantógrafo de una metodología propuesta para estructuras flexibles sometidas a cargas móviles. En primer lugar se describe el modelado de una malla móvil de elementos finitos que se desplaza sobre el hilo de contacto de forma solidaria al pantógrafo que recorre la catenaria y, posteriormente, se presenta la comparación de esta metodología frente a un modelo de elementos finitos convencional de malla fija. El caso simulado corresponde al propuesto por la norma EN-50318, obteniendo resultados acordes a los intervalos de validación propuestos por dicha norma. La principal ventaja del método de malla móvil reside en que para precisiones análogas el tiempo de cálculo es del orden de 4 veces menor que el modelo clásico.This paper presents a technological application of a general methodology to analyze cable structures under moving loads, particularly on the catenary-pantograph dynamic interaction. This work firstly describes the modeling of a finite element moving mesh which integrally moves over the contact wire following the pantograph along the whole catenary, prior focusing on its comparison against the classical finite element mesh. The case study corresponds to the standard EN-50318 one, whose results fulfill the ranges proposed by this validation rule. The main advantage of the moving mesh method is presented in the falling of computational costs about 4 times lower than the classic model with similar precision.Peer Reviewe

Simulation of moving loads on structures using a moving finite element mesh

En este artículo se presenta una metodología para analizar la respuesta dinámica de estructuras sometidas a cargas móviles. Para ello se ha desarrollado un algoritmo de mallado adaptativo de elementos finitos que se mueve de forma solidaria a la carga móvil que actúa sobre la estructura. El algoritmo de mallado móvil se ha validado con la solución analítica de una carga móvil que recorre una viga simplemente apoyada.This paper presents a methodology to analyze the dynamic behavior of structures under moving loads. A finite element moving mesh algorithm has been developed in order to integrally move a part of the mesh following a moving load. This algorithm has been validated with the analytical solution of a moving load applied on a simply supported beam.Peer Reviewe

Elaboración integral de las aceitunas con autogeneración de electricidad, comparada con el sistema actual de obtención del aceite de oliva virgen

A future solution for treatment of the olive and obtaining olive virgin oil is presented. The energy demands for which are supplied by a generation system, that also feeds other phases of manufacture of by-products, such as "orujos" drying or extraction of the residual oil contained in them. For this purpose gasifier equipment is needed, whose major fuel is plain olive stone, although "orujos" with 20% humidity could also be used. This system produces a gas which is introduced in a combustion engine connected to a generator, harnessing the electricity created to supply the plant itself. The thermal energy surplus serves to generate and sell electrical energy to distribution grid.Se pretende plantear una solución de futuro para el proceso de elaboración de las aceitunas y obtención del aceite de oliva virgen, donde se generaría la energía eléctrica consumida en la propia planta, así como en las demás fases de elaboración completa de los subproductos, como el secado de los orujos y la extracción del aceite residual contenido en los mismos.Para esto se dimensiona un equipo gasificador del hueso, separado en el proceso de obtención indicado, con el que se abastece de energía térmica a un motor de gas que acciona un generador eléctrico, que abastece todas las necesidades de la planta integral, más el excedente de energía térmica del hueso y del orujillo resultante, generando una energía con posibilidad de venta a la red de distribución eléctrica de la zona

Changes in health behaviors, mental and physical health among older adults under severe lockdown restrictions during the covid-19 pandemic in spain

We used data from 3041 participants in four cohorts of community-dwelling individuals aged =65 years in Spain collected through a pre-pandemic face-to-face interview and a telephone interview conducted between weeks 7 to 15 after the beginning of the COVID-19 lockdown. On average, the confinement was not associated with a deterioration in lifestyle risk factors (smoking, alcohol intake, diet, or weight), except for a decreased physical activity and increased sedentary time, which reversed with the end of confinement. However, chronic pain worsened, and moderate declines in mental health, that did not seem to reverse after restrictions were lifted, were observed. Males, older adults with greater social isolation or greater feelings of loneliness, those with poorer housing conditions, as well as those with a higher prevalence of chronic morbidities were at increased risk of developing unhealthier lifestyles or mental health declines with confinement. On the other hand, previously having a greater adherence to the Mediterranean diet and doing more physical activity protected older adults from developing unhealthier lifestyles with confinement. If an-other lockdown were imposed during this or future pandemics, public health programs should spe-cially address the needs of older individuals with male sex, greater social isolation, sub-optimal housing conditions, and chronic morbidities because of their greater vulnerability to the enacted movement restrictions. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

Second-line treatment in advanced gastric cancer : Data from the Spanish AGAMENON registry

Second-line treatments boost overall survival in advanced gastric cancer (AGC). However, there is a paucity of information as to patterns of use and the results achieved in actual clinical practice. The study population comprised patients with AGC in the AGAMENON registry who had received second-line. The objective was to describe the pattern of second-line therapies administered, progression-free survival following second-line (PFS-2), and post-progression survival since first-line (PPS). 2311 cases with 2066 progression events since first-line (89.3%) were recorded; 245 (10.6%) patients died during first-line treatment and 1326/2066 (64.1%) received a second-line. Median PFS-2 and PPS were 3.1 (95% CI, 2.9-3.3) and 5.8 months (5.5-6.3), respectively. The most widely used strategies were monoCT (56.9%), polyCT (15.0%), ramucirumab+CT (12.6%), platinum-reintroduction (8.3%), trastuzumab+CT (6.1%), and ramucirumab (1.1%). PFS-2/PPS medians gradually increased in monoCT, 2.6/5.1 months; polyCT 3.4/6.3 months; ramucirumab+CT, 4.1/6.5 months; platinum-reintroduction, 4.2/6.7 months, and for the HER2+ subgroup in particular, trastuzumab+CT, 5.2/11.7 months. Correlation between PFS since first-line and OS was moderate in the series as a whole (Kendall's τ = 0.613), lower in those subjects who received second-line (Kendall's τ = 0.539), especially with ramucirumab+CT (Kendall's τ = 0.413). This analysis reveals the diversity in second-line treatment for AGC, highlighting the effectiveness of paclitaxel-ramucirumab and, for a selected subgroup of patients, platinum reintroduction; both strategies endorsed by recent clinical guidelines

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.

Low muscle strength is an important heritable indicator of poor health linked to morbidity and mortality in older people. In a genome-wide association study meta-analysis of 256,523 Europeans aged 60 years and over from 22 cohorts we identify 15 loci associated with muscle weakness (European Working Group on Sarcopenia in Older People definition: n = 48,596 cases, 18.9% of total), including 12 loci not implicated in previous analyses of continuous measures of grip strength. Loci include genes reportedly involved in autoimmune disease (HLA-DQA1 p = 4 × 10-17), arthritis (GDF5 p = 4 × 10-13), cell cycle control and cancer protection, regulation of transcription, and others involved in the development and maintenance of the musculoskeletal system. Using Mendelian randomization we report possible overlapping causal pathways, including diabetes susceptibility, haematological parameters, and the immune system. We conclude that muscle weakness in older adults has distinct mechanisms from continuous strength, including several pathways considered to be hallmarks of ageing

Frequency and characteristics of familial melanoma in Spain: The FAM-GEM-1 Study

Similar to that observed in other countries, familial melanoma accounts for 6.6% of melanoma diagnoses in Spain. Although no differences in the multivariate analysis were found, some better prognosis factors, such as Breslow index, seem more frequent in familial melanoma, which reflect a better early detection marker and/or a different biological behavior

Virtualización del Título Propio en Olivicultura y Elaiotecnia. Elaboración de Materiales

Es conocido que España es primer país productor de aceite de oliva del mundo, con un 40 % de la producción mundial y el 50 % de la producción de la Unión Europea, siendo la provincia de Jaén, con el 38,4 % de la producción española, la mayor zona productora del mundo en aceite de oliva. Sin embargo, se trata de un sector en el que la escasa profesionalización es, tal vez, su mayor debilidad.La Universidad de Jaén, consciente del importante papel que ha de jugar como Institución dinamizadora del desarrollo de su entorno, en el que el sector del olivar y del aceite de oliva tiene una enorme importancia, considera que es urgente formar titulados universitarios de grado superior que posean conocimientos integrales y solventes en olivicultura y elaiotecnia de modo que incorporados a las empresas del sector del olivar y el aceite de oliva o creando las suyas propias, lo modernicen y desarrollen, contribuyendo a dotarlo de cultura empresarial y al desarrollo socioeconómico y, por ende, al bienestar de los ciudadanos de la provincia