Impactos da influenza aviária no mercado internacional de carnes

Animal infectious disease outbreaks as Avian Influenza, Foot and mouth disease and Bovine Spongiform Encephalopathy can influence trade and bring economic consequences to affected countries. For this reason, this work aims to analyze the effects on meat import demand in the years of 1997 and 2003 to 2005, the Avian Influenza outbreaks period. The analytical framework used was panel data econometrics. The results point to a reduction on chicken meat demand in 1997 and increase to the other meats, indicating a possible substitution. From 2003 on, chicken meat demand showed slight increase, as did pig meat, only bovine meat demand showed a reduction. This fact can be explained by a restriction on bovine and chicken supply caused by the imposition of sanitary barriers to the main exporting countries.Avian Influenza, Import demand, Beef, Chicken meat, Panel data, International Relations/Trade,

Cálculo do desconto do INSS sobre o salário mínimo: relato de experiência de uma aula baseada na resolução de problemas

The objective of this work is to report an experience of applying a proposal for a class that works with the theme calculation of labor discounts on the minimum wage from the perspective of the methodology of teaching-learning-evaluation Problem Solving. The methodological path is characterized by being an experience report. The theoretical framework is based on studies on the methodology of teaching-learning-assessment Problem Solving from the perspective of Norma Allevato and Lourdes Onuchic; in addition to studies on Financial Education in basic education. As main results, we point out and verify with a class planned with the methodology of teaching-learning-evaluation Problem Solving, the students became more involved and actively participated in the learning process of the mathematical content. In addition to evaluating the learning process itself. In conclusion, it is pointed out that the teaching methodology presented highlights some relevant, practical and theoretical aspects such as group work, concepts and contents related to the construction of mathematical knowledge that was carried out in a more meaningful and effective way by the students.El objetivo de este trabajo es relatar una experiencia de aplicación de una propuesta de clase que trabaja el tema cálculo de bonificaciones laborales al salario mínimo desde la perspectiva de la metodología de enseñanza-aprendizaje-evaluación Resolución de Problemas. El camino metodológico se caracteriza por ser un relato de experiencia. El marco teórico se basa en estudios sobre la metodología de enseñanza-aprendizaje-evaluación de Resolución de Problemas desde la perspectiva de Norma Allevato y Lourdes Onuchic; además de estudios sobre Educación Financiera en la educación básica. Como principales resultados, señalamos y verificamos con una clase planificada con la metodología de enseñanza-aprendizaje-evaluación Resolución de Problemas, los estudiantes se involucraron más y participaron activamente en el proceso de aprendizaje del contenido matemático. Además de evaluar el propio proceso de aprendizaje. Como conclusión, se señala que la metodología de enseñanza presentada destaca algunos aspectos prácticos y teóricos relevantes como el trabajo en grupo, conceptos y contenidos relacionados con la construcción del conocimiento matemático que se llevó a cabo de manera más significativa y eficaz por parte de los estudiantes.O objetivo deste trabalho é relatar uma experiência de uma aplicação de uma proposta de aula que trabalhe com o tema cálculos dos descontos trabalhistas no salário mínimo sob a ótica da metodologia de ensino-aprendizagem-avaliação Resolução de Problemas. O percurso metodológico é caracterizado por ser um relato de experiência. O referencial teórico é pautado em estudos sobre a metodologia de ensino-aprendizagem-avaliação Resolução de Problemas na perspectiva de Norma Allevato e Lourdes Onuchic; além de estudos sobre Educação Financeira no ensino básico. Como principais resultados, apontamos e verificamos com uma aula planejada com a metodologia de ensino-aprendizagem-avaliação Resolução de Problemas, os alunos se envolveram mais e participaram ativamente do processo de aprendizagem do conteúdo matemático. Além deles avaliarem o próprio processo de aprendizagem. Em conclusão, aponta-se que a metodologia de ensino apresentada destaca alguns aspectos relevantes, práticos e teóricos como o trabalho em grupo, conceitos e conteúdos relacionados a construção de conhecimento matemático que foi realizada de forma mais significativa e efetiva pelos alunos

Surgical treatment of gynecomastia: a critical analysis

INTRODUCTION: The gynecomastia is an increase in male breast and an important impact on quality of life. However, it is a condition likely to be modified. OBJECTIVE: To analyze the surgical treatment of gynecomastia pointing the major complications. METHODS: Two hundred and eighty-four patients underwent surgery to correct gynecomastia from January 1998 to September 2008, 94.37% of patients were grade I and II and 5.63%, grade III. RESULTS: 3.87% patients had seromas and 2.11%, hematoma (p<0.001). Patients grade I and II had keloids in incision of liposuction (0.74%) and patients grade III presented are olar enlargement. CONCLUSION: The techniques used for treatment of gynecomastia were considered safe and effective with low complication rate.INTRODUÇÃO: A ginecomastia é o aumento no tamanho da glândula mamária masculina, que pode ser fisiológico ou patológico, sendo condição passível de correção. OBJETIVO: Analisar o tratamento cirúrgico da ginecomastia, apontando suas principais complicações. MÉTODO: Duzentos e oitenta e quatro pacientes foram submetidos a cirurgia para correção da ginecomastia entre janeiro de 1998 e setembro de 2008, sendo 94,37% dos pacientes graus I e II e 5,63%, grau III. RESULTADOS: Em relação ao total de pacientes, 3,87% apresentaram seroma e 2,11%, hematoma (p<0,001). A análise dos pacientes graus I e II revela que 0,74% apresentaram cicatrizes hipertróficas nas incisões de lipoaspiração (p<0,001). Dentre os pacientes submetidos à técnica de Davidson, 18,75% apresentaram alargamento do complexo aréolo-mamilar (p=0,108) e foram submetidos a cirurgia para correção. CONCLUSÃO: As técnicas utilizadas para correção de ginecomastia se mostraram eficazes e seguras

The protective effect of Canova homeopathic medicine in cyclophosphamide-treated non-human primates

Background: Canova activates macrophages and indirectly induces lymphocyte proliferation. Here we evaluated the effects of Canova in cyclophosphamide-treated non-human primates.Methods: Twelve Cebus apella were evaluated. Four animals were treated with Canova only. Eight animals were treated with two doses of cyclophosphamide (50 mg/kg) and four of these animals received Canova. Body weight, biochemistry and hematologic analyses were performed for 40 days. Micronucleus and comet assays were performed for the evaluation of DNA damage.Results: We observed that cyclophosphamide induced abnormal WBC count in all animals. However, the group treated with cyclophosphamide plus Canova presented a higher leukocyte count than that which received only cyclophosphamide. Cyclophosphamide induced micronucleus and DNA damage in all animals. the frequency of these alterations was significantly lower in the Canova group than in the group without this medicine.Conclusions: Our results demonstrated that Canova treatment minimizes cyclophosphamide myelotoxicity in C. apella. (C) 2012 Elsevier B.V. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo, Disciplina Genet, Dept Morfol & Genet, BR-04023900 São Paulo, BrazilUniv São Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP, BrazilFed Univ Para, Lab Citogenet Humana, Inst Ciencias Biol, BR-66059 Belem, Para, BrazilUniversidade Federal de São Paulo, Disciplina Ginecol, Dept Tocoginecol, BR-04039032 São Paulo, BrazilFed Univ Para, Serv Cirurgia, Hosp Univ Joao de Barros Barreto, BR-66073000 Belem, Para, BrazilMinist Saude, Ctr Nacl Primatas, BR-77030000 Ananindeua, PA, BrazilUniv Fed Piaui, Lab Genet & Biol Mol, BR-64202020 Parnaiba, PI, BrazilUniversidade Federal de São Paulo, Disciplina Genet, Dept Morfol & Genet, BR-04023900 São Paulo, BrazilUniversidade Federal de São Paulo, Disciplina Ginecol, Dept Tocoginecol, BR-04039032 São Paulo, BrazilCNPq: 550885/2007-2Web of Scienc

Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital

OBJECTIVES: To prospectively evaluate demographic, anthropometric and health-related quality of life (HRQoL) in pediatric patients with laboratory-confirmed coronavirus disease 2019 (COVID-19) METHODS: This was a longitudinal observational study of surviving pediatric post-COVID-19 patients (n=53) and pediatric subjects without laboratory-confirmed COVID-19 included as controls (n=52) was performed. RESULTS: The median duration between COVID-19 diagnosis (n=53) and follow-up was 4.4 months (0.8-10.7). Twenty-three of 53 (43%) patients reported at least one persistent symptom at the longitudinal follow-up visit and 12/53 (23%) had long COVID-19, with at least one symptom lasting for &gt;12 weeks. The most frequently reported symptoms at the longitudinal follow-up visit were headache (19%), severe recurrent headache (9%), tiredness (9%), dyspnea (8%), and concentration difficulty (4%). At the longitudinal follow-up visit, the frequencies of anemia (11%&nbsp;versus&nbsp;0%,&nbsp;p=0.030), lymphopenia (42%&nbsp;versus&nbsp;18%,&nbsp;p=0.020), C-reactive protein level of &gt;30 mg/L (35%&nbsp;versus&nbsp;0%,&nbsp;p=0.0001), and D-dimer level of &gt;1000 ng/mL (43%&nbsp;versus&nbsp;6%,&nbsp;p=0.0004) significantly reduced compared with baseline values. Chest X-ray abnormalities (11%&nbsp;versus&nbsp;2%,&nbsp;p=0.178) and cardiac alterations on echocardiogram (33%&nbsp;versus&nbsp;22%,&nbsp;p=0.462) were similar at both visits. Comparison of characteristic data between patients with COVID-19 at the longitudinal follow-up visit and controls showed similar age (p=0.962), proportion of male sex (p=0.907), ethnicity (p=0.566), family minimum monthly wage (p=0.664), body mass index (p=0.601), and pediatric pre-existing chronic conditions (p=1.000). The Pediatric Quality of Live Inventory 4.0 scores, median physical score (69 [0-100]&nbsp;versus&nbsp;81 [34-100],&nbsp;p=0.012), and school score (60 [15-100]&nbsp;versus&nbsp;70 [15-95],&nbsp;p=0.028) were significantly lower in pediatric patients with COVID-19 at the longitudinal follow-up visit than in controls. CONCLUSIONS: Pediatric patients with COVID-19 showed a longitudinal impact on HRQoL parameters, particularly in physical/school domains, reinforcing the need for a prospective multidisciplinary approach for these patients. These data highlight the importance of closer monitoring of children and adolescents by the clinical team after COVID-19

Determinants of intensive insulin therapeutic regimens in patients with type 1 diabetes: data from a nationwide multicenter survey in Brazil

Background: To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D).Methods: This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups.Results: We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used therapeutic regimen. CSII was used by 37 (1.2%) patients and IT by 2,669 (90.2%) patients. More patients on IT performed self-monitoring of blood glucose and were treated at the tertiary care level compared to CT patients (p < 0.001). the majority of patients from all groups had HbA1c levels above the target. Overweight or obesity was not associated with insulin regimen. Logistic regression analysis showed that economic status, age, ethnicity, and level of care were associated with IT (p < 0.001).Conclusions: Given the prevalence of intensive treatment for T1D in Brazil, more effective therapeutic strategies are needed for long term-health benefits.Farmanguinhos/Fundacao Oswaldo Cruz/National Health MinistryBrazilian Diabetes SocietyFundacao do Amparo a Pesquisa do Estado do Rio de JaneiroConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Estado Rio de Janeiro, Unit Diabet, BR-20551030 Rio de Janeiro, BrazilBaurus Diabet Assoc, São Paulo, BrazilFed Univ São Paulo State, Diabet Unit, São Paulo, BrazilFed Univ Hosp Porto Alegre, Porto Alegre, BrazilUniv Hosp São Paulo, Diabet Unit, São Paulo, BrazilUniv Fed Rio de Janeiro, Rio de Janeiro, BrazilUniv Fed Ceara, Fortaleza, Ceara, BrazilSanta Casa Misericordia, Belo Horizonte, MG, BrazilSanta Casa Misericordia São Paulo, São Paulo, BrazilUniv Fed Amazonas, Manaus, Amazonas, BrazilHosp Geral de Bonsucesso, Rio de Janeiro, BrazilHosp Univ Clementino Fraga Filho IPPMG, Rio de Janeiro, BrazilUniv Hosp São Paulo, São Paulo, BrazilFac Ciencias Med Santa Casa São Paulo, São Paulo, BrazilUniv São Paulo, Inst Crianca, Hosp Clin, São Paulo, BrazilUniv São Paulo, Fac Med Ribeirao Preto, Hosp Clin, Ribeirao Preto, BrazilAmbulatorio Fac Estadual Med Sao Jose Rio Preto, Ribeirao Preto, BrazilEscola Paulista Med, Ctr Diabet, Ribeirao Preto, BrazilClin Endocrinol Santa Casa Belo Horizonte, Belo Horizonte, MG, BrazilUniv Estadual Londrina, Londrina, BrazilUniv Fed Parana, Hosp Clin, Porto Alegre, RS, BrazilInst Crianca Com Diabet Rio Grande Sul, Rio Grande Do Sul, RS, BrazilGrp Hosp Conceicao, Inst Crianca Com Diabet, Porto Alegre, RS, BrazilHosp Univ Santa Catarina, Florianopolis, SC, BrazilInst Diabet Endocrinol Joinville, Joinville, BrazilHosp Reg Taguatinga, Brasilia, DF, BrazilHosp Geral Goiania, Goiania, Go, BrazilCtr Diabet & Endocrinol Estado Bahia, Goiania, Go, BrazilUniv Fed Maranhao, Sao Luis, BrazilCtr Integrado Diabet & Hipertensao Ceara, Fortaleza, Ceara, BrazilUniv Fed Sergipe, Aracaju, BrazilHosp Univ Alcides Carneiro, Campina Grande, BrazilHosp Univ Joao de Barros Barreto, Belem, Para, BrazilFed Univ São Paulo State, Diabet Unit, São Paulo, BrazilUniv Hosp São Paulo, Diabet Unit, São Paulo, BrazilUniv Hosp São Paulo, São Paulo, BrazilEscola Paulista Med, Ctr Diabet, Ribeirao Preto, BrazilWeb of Scienc

Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group

Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities