Reaching the Thai People of Southeast Asia: A Model for Discipleship and Leadership Training

This thesis addresses training the Thai national leadership in discipleship and leadership qualities to develop a church planting movement with the main goal of evangelizing the unreached people groups throughout the countries of China, Vietnam, Laos, Thailand and Myanmar. The Thai have become dependent on foreign funds and though they are an independent people, they are beginning to realize that there are strings attached—with money comes control. The model will be built around a sustainable farm, which will help in developing vocational skills in order to become indigenous and autonomous. In this thesis it is my purpose to present a plan to help them reach the goal of a church planting movement by developing discipleship and leadership training

Online grooming:moves and strategies

Using transcripts of chatroom grooming interactions, this paper explores and evaluates the usefulness of Swales’ (1981) move analysis framework in contributing to the current understanding of online grooming processes. The framework is applied to seven transcripts of grooming interactions taken from perverted-justice.com. The paper presents 14 identified rhetorical moves used in chatroom grooming and explores the broad structures that grooming conversations take by presenting these structures as colour-coded visualisations which we have termed “move maps”. It also examines how some individual linguistic features are used to realise a single move termed “Assessing and Managing Risk”. The findings suggest that move analysis can usefully contribute in two key ways: determining communicative functions associated with 'grooming language' and the visualisation of variation between grooming interactions

Comorbidities and Race/Ethnicity Among Adults with Stimulant Use Disorders in Residential Treatment

Comorbid physical and mental health problems are associated with poorer substance abuse treatment outcomes; however, little is known about these conditions among stimulant abusers at treatment entry. This study compared racial and ethnic groups on baseline measures of drug use patterns, comorbid physical and mental health disorders, quality of life, and daily functioning among cocaine and stimulant abusing/dependent patients. Baseline data from a multi-site randomized clinical trial of vigorous exercise as a treatment strategy for a diverse population of stimulant abusers (N = 290) were analyzed. Significant differences between groups were found on drug use characteristics, stimulant use disorders, and comorbid mental and physical health conditions. Findings highlight the importance of integrating health and mental health services into substance abuse treatment and could help identify potential areas for intervention to improve treatment outcomes for racial and ethnic minority groups

A framework for the co-benefits and trade- offs of resilience & sustainability certification programs

Although concepts of resiliency and sustainability have long been tenets within the culture of design, their modern classification, measurement, and codification in the late 20th and early 21st century are fiercely debated. The need to reduce greenhouse gas (GHG) emissions and mitigate the impacts of global climate change influence current debates around the ways in which to operationalize sustainability and resilience within the built environment. This debate contributes to the confounding relationship between the consensus of ‘sustainability' (i.e. carbon reduction) and the myriad domains of ‘resilience' for designers, which include ecosystems, cities, communities, and individual buildings. The clarity of this debate is further attenuated in the variety of outcomes it seeks, the timescales in which it operates, and the necessary tradeoffs inherent in the process. While sustainability is concerned with resource use and the "carrying capacity of the earth” (Moffatt 2014), increases in manmade and natural disasters have focused attention on how design professionals evaluate both building's impact on the environment (sustainability) and the environment's impact on building (resilience). This paper proposes a framework for describing the synergies and discords that occur between several ‘resilience' and ‘sustainability' building certification programs (BCP). The evolution of various concepts of resilience are briefly explored and used to later inform this framework. Several BCPs are cited within this framework. A matrix showing the relationships between multiple green building rating systems and resilience rating systems is used to incorporate the interpretations of resilience cited in this paper. This comparison includes the rating system origin, application, and range of implementation as it considers resilience scholarship. The table aims to identify the problems, objectives, and co-benefits of various green building rating criteria and resilience criteria. Comparing several rating systems, the gaps and overlapping objectives in each system are identified as they relate to ‘sustainability' or ‘resiliency' outcomes

Contingent infrastructure and the dilution of ‘Chineseness’: Reframing roads and rail in Kampala and Addis Ababa

Amid growing interest in China’s role in financing and building infrastructure in Africa, there is still little research on how Chinese-financed infrastructures are negotiated and realised at the city and metropolitan scale. We compare the Light Rail Transit in Addis Ababa, Ethiopia with the expressway linking Kampala to Entebbe airport in Uganda, examining the processes of bargaining behind these transport infrastructures and their emergent effects on urban land use and city-dwellers’ mobility. We find that both projects were designed and implemented through opaque negotiations between African national elites and Chinese agencies, with little or no engagement from city authorities, leading to haphazard outcomes that are poorly integrated with broader planning. Yet we also suggest that despite being enabled and mediated by Chinese agencies, such projects do not embody a Chinese global vision. They instead reflect the entrepreneurial activities of Chinese contractors and the varying ways in which these connect with African national governments’ shifting priorities. Moreover, as they are subsumed into the urban context, these transposed infrastructures have been rapidly repurposed and their ‘Chineseness’ diluted, with one morphing into an infrastructure for the poor and the other into a site of private value extraction. We thus argue that, far from representing a domineering or neo-colonial influence, Chinese-financed infrastructures that land in institutionally complex African city-regions can be rapidly swallowed up into the political-economic landscape, producing contingent benefits and disbenefits that are far removed from the visions of any planners – Chinese or African, past or present

Significantly different clinical phenotypes associated with mutations in synthesis and transamidase+remodeling glycosylphosphatidylinositol (GPI)-anchor biosynthesis genes.

BACKGROUND: Defects in the glycosylphosphatidylinositol (GPI) biosynthesis pathway can result in a group of congenital disorders of glycosylation known as the inherited GPI deficiencies (IGDs). To date, defects in 22 of the 29 genes in the GPI biosynthesis pathway have been identified in IGDs. The early phase of the biosynthetic pathway assembles the GPI anchor (Synthesis stage) and the late phase transfers the GPI anchor to a nascent peptide in the endoplasmic reticulum (ER) (Transamidase stage), stabilizes the anchor in the ER membrane using fatty acid remodeling and then traffics the GPI-anchored protein to the cell surface (Remodeling stage). RESULTS: We addressed the hypothesis that disease-associated variants in either the Synthesis stage or Transamidase+Remodeling-stage GPI pathway genes have distinct phenotypic spectra. We reviewed clinical data from 58 publications describing 152 individual patients and encoded the phenotypic information using the Human Phenotype Ontology (HPO). We showed statistically significant differences between the Synthesis and Transamidase+Remodeling Groups in the frequencies of phenotypes in the musculoskeletal system, cleft palate, nose phenotypes, and cognitive disability. Finally, we hypothesized that phenotypic defects in the IGDs are likely to be at least partially related to defective GPI anchoring of their target proteins. Twenty-two of one hundred forty-two proteins that receive a GPI anchor are associated with one or more Mendelian diseases and 12 show some phenotypic overlap with the IGDs, represented by 34 HPO terms. Interestingly, GPC3 and GPC6, members of the glypican family of heparan sulfate proteoglycans bound to the plasma membrane through a covalent GPI linkage, are associated with 25 of these phenotypic abnormalities. CONCLUSIONS: IGDs associated with Synthesis and Transamidase+Remodeling stages of the GPI biosynthesis pathway have significantly different phenotypic spectra. GPC2 and GPC6 genes may represent a GPI target of general disruption to the GPI biosynthesis pathway that contributes to the phenotypes of some IGDs

The Effect of Attractiveness on Food Sharing Preferences in Human Mating Markets

The current study explored how physical attractiveness affects food sharing by studying payment preferences for hypothetical romantic dinner dates (a hypothetical mating market). We analyzed payment preferences, self-rated attractiveness, and rated attractiveness for hypothetical dates in 416 participants. We hypothesized that (1) men would be more likely to prefer to pay than would women, (2) attractive individuals of both sexes would be less willing to pay, and (3) preferences to enter an exchange would be influenced by the attractiveness of prospective partners such that (3a) men would prefer to pay for attractive women, and (3b) women would prefer to be paid for by attractive men. All hypotheses were supported by our results. Individuals with higher self-rated attractiveness were more likely to prefer that their date would pay for the meal, and we found clear sex differences in how the attractiveness of potential dates affected payment preferences. Male participants preferred to pay for dates that had higher facial attractiveness, while female participants preferred that attractive men would pay. Individuals show condition dependent financial preferences consistent with the provisioning hypothesis in this mating market that are adaptive to evaluations of their own quality and that of prospective partners

More than a Metric:How Training Load is Used in Elite Sport for Athlete Management

Training load monitoring is a core aspect of modern-day sport science practice. Collecting, cleaning, analysing, interpreting, and disseminating load data is usually undertaken with a view to improve player performance and/or manage injury risk. To target these outcomes, practitioners attempt to optimise load at different stages throughout the training process, like adjusting individual sessions, planning day-to-day, periodising the season, and managing athletes with a long-term view. With greater investment in training load monitoring comes greater expectations, as stakeholders count on practitioners to transform data into informed, meaningful decisions. In this editorial we highlight how training load monitoring has many potential applications and cannot be simply reduced to one metric and/or calculation. With experience across a variety of sporting backgrounds, this editorial details the challenges and contextual factors that must be considered when interpreting such data. It further demonstrates the need for those working with athletes to develop strong communication channels with all stakeholders in the decision-making process. Importantly, this editorial highlights the complexity associated with using training load for managing injury risk and explores the potential for framing training load with a performance and training progression mindset.</p